Bajic G, et al. Autoreactivity profiles of influenza hemagglutinin broadly neutralizing antibodies. Sci Rep. 2019 Mar 5;9(1):3492.. Abstract
submitted by kickingbird at Mar, 8, 2019 from Sci Rep. 2019 Mar 5;9(1):3492. (via https://www.nature.com/articles/s41598-019-40175-8)
Epitope-focused approaches for selective clonal induction of broadly neutralizing antibodies (bnAbs) inform most current vaccine strategies for influenza virus and other rapidly evolving pathogens. The ...
Taniguchi K, et al. Inhibition of avian-origin influenza A(H7N9) virus by the novel cap-dependent endonuclease inhibitor baloxavir marboxil. Sci Rep. 2019 Mar 5;9(1):3466.. Abstract
submitted by kickingbird at Mar, 8, 2019 from Sci Rep. 2019 Mar 5;9(1):3466. (via https://www.nature.com/articles/s41598-019-39683-4)
Human infections with avian-origin influenza A(H7N9) virus represent a serious threat to global health; however, treatment options are limited. Here, we show the inhibitory effects of baloxavir acid (BXA) ...
Bragstad K, et al. Community spread and late season increased incidence of oseltamivir-resistant influenza A(H1N1) viruses in Norway 2016. Influenza Other Respir Viruses. 2019 Mar 4.. Abstract
submitted by kickingbird at Mar, 8, 2019 from Influenza Other Respir Viruses. 2019 Mar 4. (via https://onlinelibrary.wiley.com/doi/full/10.1111/irv.12637)
BACKGROUND: Antiviral resistance in Norwegian influenza viruses is rare. Only one A(H1N1)pdm09 virus from May 2015 had been found resistant to oseltamivir since the introduction of these viruses in 2009.OBJECTIVES: ...
Uyeki TM, et al. Clinical Practice Guidelines by the Infectious Diseases Society of America: 2018 Update on Diagnosis, Treatment, Chemoprophylaxis, and Institutional Outbreak Management of Seasonal Influenza. Clin Infect Dis. 2019 Mar 5;68(6):895-902. Abstract
submitted by kickingbird at Mar, 8, 2019 from Clin Infect Dis. 2019 Mar 5;68(6):895-902 (via https://academic.oup.com/cid/article/68/6/895/5369363)
Seasonal influenza A and B virus epidemics are associated with significant morbidity and mortality each year in the United States and worldwide. One study estimated that during 2010–2016, the seasonal ...
Nu?ez IA, Ross TM. A review of H5Nx avian influenza viruses. Ther Adv Vaccines Immunother. 2019 Feb 22;7:251513. Abstract
submitted by kickingbird at Mar, 7, 2019 from Ther Adv Vaccines Immunother. 2019 Feb 22;7:251513 (via https://journals.sagepub.com/doi/10.1177/2515135518821625)
Highly pathogenic avian influenza viruses (HPAIVs), originating from the A/goose/Guangdong/1/1996 H5 subtype, naturally circulate in wild-bird populations, particularly waterfowl, and often spill over ...
Pramuwidyatama MG, et al. A Systematic Evaluation of Measures Against Highly Pathogenic Avian Influenza (HPAI) in Indonesia. Front Vet Sci. 2019 Feb 18;6:33.. Abstract
submitted by kickingbird at Mar, 7, 2019 from Front Vet Sci. 2019 Feb 18;6:33. (via https://www.frontiersin.org/articles/10.3389/fvets.2019.0003)
Over the past years, many different control measures have been implemented to prevent HPAI infection. The national plan with numerous measures lead to problems in terms of prioritization and budget allocation. ...
Kouam MK, Tchouankui HN, Ngapagna AN. Epidemiological Features of Highly Pathogenic Avian Influenza in Cameroon. Vet Med Int. 2019 Jan 27;2019:3796369.. Abstract
submitted by kickingbird at Mar, 7, 2019 from Vet Med Int. 2019 Jan 27;2019:3796369. (via https://www.hindawi.com/journals/vmi/2019/3796369/)
The epidemiology of avian influenza is unknown in Cameroon despite the two outbreaks that occurred in 2006 and 2016-2017, respectively. In order to fill the gap, an attempt was made to provide some basic ...
Ainslie KEC, Haber M, Orenstein WA. Bias of influenza vaccine effectiveness estimates from test-negative studies conducted during an influenza pandemic. Vaccine. 2019 Mar 1.. Abstract
submitted by kickingbird at Mar, 7, 2019 from Vaccine. 2019 Mar 1. (via https://www.sciencedirect.com/science/article/pii/S0264410X1)
Test-negative (TN) studies have become the most widely used study design for the estimation of influenza vaccine effectiveness (VE) and are easily incorporated into existing influenza surveillance networks. ...
Chen R, Fang Z, Huang Y. Neuropsychiatric events in an adult patient with influenza a (H3N2) treated with oseltamivir (Tamiflu): a case report. BMC Infect Dis. 2019 Mar 4;19(1):224. Abstract
submitted by kickingbird at Mar, 7, 2019 from BMC Infect Dis. 2019 Mar 4;19(1):224 (via https://bmcinfectdis.biomedcentral.com/articles/10.1186/s128)
BACKGROUND: Total four influenza pandemics have happened since twentieth century, and currently influenza is in the seasonal epidemic around the world, with a sharp increase in its incidence each year. ...
Singh M, et al. Impact of demographic disparities in social distancing and vaccination on influenza epidemics in urban and rural regions of the United States. BMC Infect Dis. 2019 Mar 4;19(1):221.. Abstract
submitted by kickingbird at Mar, 7, 2019 from BMC Infect Dis. 2019 Mar 4;19(1):221. (via https://bmcinfectdis.biomedcentral.com/articles/10.1186/s128)
BACKGROUND: Self-protective behaviors of social distancing and vaccination uptake vary by demographics and affect the transmission dynamics of influenza in the United States. By incorporating the socio-behavioral ...
Ianevski A, et al. Low Temperature and Low UV Indexes Correlated with Peaks of Influenza Virus Activity in Northern Europe during 2010~2018. Viruses. 2019 Mar 1;11(3).. Abstract
submitted by kickingbird at Mar, 7, 2019 from Viruses. 2019 Mar 1;11(3). (via https://www.mdpi.com/1999-4915/11/3/207)
With the increasing pace of global warming, it is important to understand the role of meteorological factors in influenza virus (IV) epidemics. In this study, we investigated the impact of temperature, ...
Beale DJ, et al. Untargeted metabolomics analysis of the upper respiratory tract of ferrets following influenza A virus infection and oseltamivir treatment. Metabolomics. 2019 Mar 1;15(3):33. Abstract
submitted by kickingbird at Mar, 5, 2019 from Metabolomics. 2019 Mar 1;15(3):33 (via https://link.springer.com/article/10.1007%2Fs11306-019-1499-)
INTRODUCTION: Influenza is a highly contagious respiratory disease that causes high global morbidity and mortality each year. The dynamics of an influenza infection on the host metabolism, and how metabolism ...
Zhang D, et al. The effectiveness of influenza vaccination in preventing hospitalizations in elderly in Beijing, 2016~18. Vaccine. 2019 Feb 28.. Abstract
submitted by kickingbird at Mar, 5, 2019 from Vaccine. 2019 Feb 28. (via https://www.sciencedirect.com/science/article/pii/S0264410X1)
BACKGROUND: Influenza vaccinations play an important role in preventing influenza related hospitalizations. The objective of this study was to estimate the effectiveness of vaccination in protecting Beijing ...
Joanna A. Pulit-Penaloza, et al. Sowing the Seeds of a Pandemic? Mammalian Pathogenicity and Transmissibility of H1 Variant Influenza Viruses from the Swine Reservoir. Trop Med Infect Dis. 2019 Feb 27;4(1).. Abstract
submitted by kickingbird at Mar, 4, 2019 from Trop Med Infect Dis. 2019 Feb 27;4(1). (via https://www.mdpi.com/2414-6366/4/1/41)
Emergence of genetically and antigenically diverse strains of influenza to which the human population has no or limited immunity necessitates continuous risk assessments to determine the likelihood of ...
Sisteré-Oró M, et al. Conserved HA-peptide NG34 formulated in pCMV-CTLA4-Ig reduces viral shedding in pigs after a heterosubtypic influenza virus SwH3N2 challenge. PLoS One. 2019 Mar 1;14(3):e0212431. Abstract
submitted by kickingbird at Mar, 4, 2019 from PLoS One. 2019 Mar 1;14(3):e0212431 (via https://journals.plos.org/plosone/article?id=10.1371/journal)
Swine influenza viruses (SIVs), the causal agents of swine influenza, are not only important to control due to the economic losses in the swine industry, but also can be pandemic pathogens. Vaccination ...
Zhang Y, Yakob L, Bonsall MB, Hu W. Predicting seasonal influenza epidemics using cross-hemisphere influenza surveillance data and local internet query data. Sci Rep. 2019 Mar 1;9(1):3262.. Abstract
submitted by kickingbird at Mar, 3, 2019 from Sci Rep. 2019 Mar 1;9(1):3262. (via https://www.nature.com/articles/s41598-019-39871-2)
Can early warning systems be developed to predict influenza epidemics? Using Australian influenza surveillance and local internet search query data, this study investigated whether seasonal influenza epidemics ...
Umut Karakus, et al. MHC class II proteins mediate cross-species entry of bat influenza viruses. Nature 20 Feb, 2019. Abstract
submitted by kickingbird at Mar, 3, 2019 from Nature 20 Feb, 2019 (via https://www.nature.com/articles/s41586-019-0955-3)
Zoonotic influenza A viruses of avian origin can cause severe disease in individuals, or even global pandemics, and thus pose a threat to human populations. Waterfowl and shorebirds are believed to be ...
Barnes B, et al. Modelling high pathogenic avian influenza outbreaks in the commercial poultry industry. Theor Popul Biol. 2019 Feb 27.. Abstract
submitted by kickingbird at Mar, 3, 2019 from Theor Popul Biol. 2019 Feb 27. (via https://www.sciencedirect.com/science/article/pii/S004058091)
Highly pathogenic avian influenza (HPAI) outbreaks are devastating to poultry industries and pose a risk to human health. There is concern that demand for free-range poultry products could increase the ...
Lim KS, et al. Direct visualization of avian influenza H5N1 Hemagglutinin precursor and its conformational change by high-speed atomic force microscopy. Biochim Biophys Acta Gen Subj. 2019 Feb 27.. Abstract
submitted by kickingbird at Mar, 3, 2019 from Biochim Biophys Acta Gen Subj. 2019 Feb 27. (via https://www.sciencedirect.com/science/article/pii/S030441651)
BACKGROUND: Hemagglutinin (HA) of influenza A is one of the key virulence factors that mediates the release of viral components in host cells. HA is initially synthesized as a trimeric precursor (HA0) ...
Paulino J, Pang X, Hung I, Zhou HX, Cross TA. Influenza A M2 Channel Clustering at High Protein/Lipid Ratios: Viral Budding Implications. Biophys J. 2019 Feb 10. Abstract
submitted by kickingbird at Mar, 3, 2019 from Biophys J. 2019 Feb 10 (via https://www.cell.com/biophysj/fulltext/S0006-3495(19)30114-6)
Protein dynamics in crowded environments is important for understanding protein functions in vivo and is especially relevant for membrane proteins because of the roles of protein-protein interactions in ...
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