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2025-4-1 2:23:53
Article

Huizi Li, etc.,al. Chicken C4BPM facilitates replication of H5N1 and H9N2 Avian Influenza Viruses by inhibiting the production of type I interferons. Poultry Science, Volume 104, Issue 3, March 2025.  Abstract  
submitted by kickingbird at Feb, 21, 2025 from Poultry Science, Volume 104, Issue 3, March 2025 (via https://www.sciencedirect.com/science/article/pii/S003257912)
Avian influenza viruses (AIVs) are potential pandemic of global concern, posing a major threat to both the poultry industry and human health. Host factors play a key role in the replication of AIVs, while ...

Samson Oladokun, Mohammadali Alizadeh, Amirul I Ma. Influenza A Virus Subtype H9N2 Infection Induces Respiratory Microbiota Dysbiosis in Chickens via Type-I Interferon-Mediated Mechanisms. FEMS Microbes, 2025;, xtaf001.  Abstract  
submitted by kickingbird at Feb, 21, 2025 from FEMS Microbes, 2025;, xtaf001 (via https://academic.oup.com/femsmicrobes/advance-article/doi/10)
Avian influenza virus (AIV) poses significant threats to poultry and human health. This study investigates the impact of H9N2 AIV infection on the respiratory microbiota of chickens using 16S rRNA gene ...

Albert Perlas, Tim Reska, Guillaume Croville, Ferr. Improvements in RNA and DNA nanopore sequencing allow for rapid genetic characterization of avian influenza. Virus Evolution, 2025;, veaf010.  Abstract  
submitted by kickingbird at Feb, 21, 2025 from Virus Evolution, 2025;, veaf010 (via https://academic.oup.com/ve/advance-article/doi/10.1093/ve/v)
Avian influenza virus (AIV) currently causes a panzootic with extensive mortality in wild birds, poultry, and wild mammals, thus posing a major threat to global health and underscoring the need for efficient ...

Kilany WH, Safwat M, Zain El-Abideen MA, Hisham I,. Multivalent Inactivated Vaccine Protects Chickens from Distinct Clades of Highly Pathogenic Avian Influenza Subtypes H5N1 and H5N8. Vaccines. 2025; 13(2):204.  Abstract  
submitted by kickingbird at Feb, 21, 2025 from Vaccines. 2025; 13(2):204 (via https://www.mdpi.com/2076-393X/13/2/204)
Background/Objective: Highly pathogenic avian influenza (HPAI) H5 subtype remains a significant menace to both the poultry industry and human public health. Biosecurity and mass vaccination of susceptible ...

Zhou S, Zhang Y, Liu S, Peng C, Shang J, Tian J, L. Pathogenicity of Novel H3 Avian Influenza Viruses in Chickens and Development of a Promising Vaccine. Viruses. 2025; 17(3):288.  Abstract  
submitted by kickingbird at Feb, 21, 2025 from Viruses. 2025; 17(3):288 (via https://www.mdpi.com/1999-4915/17/3/288)
Since 2022, three cases of human infections of novel H3N8 avian influenza viruses (AIVs) have been confirmed in China. Given the potential for significant public health implications, the prompt detection ...

Naraharisetti R, Weinberg M, Stoddard B, et al. Highly Pathogenic Avian Influenza A(H5N1) Virus Infection of Indoor Domestic Cats Within Dairy Industry Worker Households - Michigan, May 2024. MMWR Morb Mortal Wkly Rep 2025;74:61-65.  Abstract  
submitted by kickingbird at Feb, 21, 2025 from MMWR Morb Mortal Wkly Rep 2025;74:61-65 (via https://www.cdc.gov/mmwr/volumes/74/wr/mm7405a2.htm)
Highly pathogenic avian influenza (HPAI) A(H5N1) virus, clade 2.3.4.4b, genotype B3.13 infection has been documented in cats on U.S. dairy cattle farms. In May 2024, the detection of HPAI A(H5N1) virus ...

Li X, Li L, Tian J, Su R, Sun J, Li Y, Wang L, Zho. SREBP2-dependent lipid droplet formation enhances viral replication and deteriorates lung injury in mice following IAV infection. Emerg Microbes Infect. 2025 Feb 19:2470371.  Abstract  
submitted by kickingbird at Feb, 20, 2025 from Emerg Microbes Infect. 2025 Feb 19:2470371 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2)
Influenza A virus (IAV) is a significant zoonotic pathogen that poses a considerable challenge to public health due to its continuous mutations. Lipid droplets (LDs) have been shown to play an important ...

Llanos-Soto SG, Yaffy D, Pavlak M, Ivanek R. Transmission dynamics of highly pathogenic avian influenza among multiple waterfowl species and backyard poultry: the impact of the stopover period. Sci Rep. 2025 Feb 18;15(1):5861.  Abstract  
submitted by kickingbird at Feb, 20, 2025 from Sci Rep. 2025 Feb 18;15(1):5861 (via https://www.nature.com/articles/s41598-025-89827-y)
Spillover of Highly Pathogenic Avian Influenza (HPAI) to backyard poultry via migratory birds threatens the poultry industry and public health. To improve the understanding of spillover events, we developed ...

Wang L, Bu S, Meng H, Zhang X, Zhou H, Xu C, Hao Z. Lateral flow biosensor development for the visual identification of H1N1 virus based on primer extension nucleic acid isothermal amplification and M13mp18 single-stranded DNA. Mikrochim Acta. 2025 Feb 18;192(3):171.  Abstract  
submitted by kickingbird at Feb, 20, 2025 from Mikrochim Acta. 2025 Feb 18;192(3):171 (via https://link.springer.com/article/10.1007/s00604-025-07031-1)
A lateral flow biosensor was developed based on newly established primer extension nucleic acid isothermal amplification (PEIA) and M13mp18 single-stranded DNA (ssDNA) to visually identify the H1N1 virus. ...

Skaarup KG, Davidovski FS, Durukan E, Modin D, Las. Cardiac Characteristics of Hospitalized Influenza Patients: An Interim Analysis From the FluHeart Study. Influenza Other Respir Viruses. 2025 Feb;19(2):e70.  Abstract  
submitted by kickingbird at Feb, 20, 2025 from Influenza Other Respir Viruses. 2025 Feb;19(2):e70 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.70067)
Background: Influenza infection has been associated with multiple cardiac complications including acute heart failure and myocardial infarction. The FluHeart study aims to uncover the potential effect ...

Signore AV, Joseph T, Ranadheera C, Erdelyan CNG,. Neuraminidase reassortment and oseltamivir resistance in clade 2.3.4.4b A(H5N1) viruses circulating among Canadian poultry, 2024. Emerg Microbes Infect. 2025 Feb 18:2469643.  Abstract  
submitted by kickingbird at Feb, 20, 2025 from Emerg Microbes Infect. 2025 Feb 18:2469643 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2)
We report the detection of a clade 2.3.4.4b A(H5N1) reassortant virus with a neuraminidase surface protein derived from a North American lineage low-pathogenic avian influenza virus. This virus caused ...

Ibrahim S, Spackman E, Suarez DL, Goraichuk IV, Le. Evaluation of an N1 NA antibody-specific enzyme-linked lectin assay for detection of H5N1 highly pathogenic avian influenza virus infection in vaccinated birds. J Virol Methods. 2025 Feb 14:115127.  Abstract  
submitted by kickingbird at Feb, 18, 2025 from J Virol Methods. 2025 Feb 14:115127 (via https://www.sciencedirect.com/science/article/pii/S016609342)
Unprecedented H5N1 highly pathogenic avian influenza (HPAI) outbreaks are occurring around the world and there is growing interest in the use of vaccines in affected regions. Vaccination when properly ...

Wu J, Zhang X, Zhao Y, Zhang S, Wang Y, Yang W, Li. North American-Origin Influenza A (H10) viruses in Eurasian Wild Birds (2022-2024): Implications for the Emergence of Human H10N5 Virus. Emerg Microbes Infect. 2025 Feb 17:2465308.  Abstract  
submitted by kickingbird at Feb, 18, 2025 from Emerg Microbes Infect. 2025 Feb 17:2465308 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2)
During our surveillance of avian influenza viruses (AIVs) in wild birds across China, H10Nx viruses were isolated from diverse migratory flyways between 2022 and 2024. We identified one wild-bird H10N5 ...

Cheng Z, Sun Y, Shen Y, Wu X, Pan L, Wu H, Bai Y,. A Single Mutation at Position 214 of Influenza B Hemagglutinin Enhances Cross-Neutralization. Emerg Microbes Infect. 2025 Feb 17:2467770.  Abstract  
submitted by kickingbird at Feb, 18, 2025 from Emerg Microbes Infect. 2025 Feb 17:2467770 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2)
High variability of influenza B virus (IBV) hemagglutinin (HA) impairs the cross- neutralization ability of vaccines, leading to reduce efficacy. We identified significant differences in cross-neutralization ...

Oona Liedes, etc.,al. [preprint]Inactivated Zoonotic Influenza A(H5N8) Vaccine Induces Robust Antibody Responses Against Recent Highly Pathogenic Avian Influenza Clade 2.3.4.4b A(H5N1) Viruses. https://doi.org/10.1101/2025.02.12.25322044.  Abstract  
submitted by kickingbird at Feb, 17, 2025 from https://doi.org/10.1101/2025.02.12.25322044 (via https://www.medrxiv.org/content/10.1101/2025.02.12.25322044v)
In 2023, Finland faced an outbreak of highly pathogenic avian influenza caused by clade 2.3.4.4b A(H5N1) viruses, which spread from wild birds to fur farms. Vaccinations of individuals at-risk, such as ...

Han J, Kim S, Kang D, Lee SH, Cho AY, Lee H, Kwon. Near-Infrared Long-Lived Luminescent Nanoparticle-Based Time-Gated Imaging for Background-Free Detection of Avian Influenza Virus. ACS Sens. 2025 Feb 15.  Abstract  
submitted by kickingbird at Feb, 17, 2025 from ACS Sens. 2025 Feb 15 (via https://pubs.acs.org/doi/10.1021/acssensors.4c03202)
Near-infrared (NIR)-to-NIR upconversion nanoparticles (UCNPs) are promising materials for biomedical imaging and sensing applications. However, UCNPs with long lifetimes continue to face the limitation ...

Chen C, Li M, Guo A, Guo P, Zhang W, Gu C, Wen G,. Addressing unexpected bacterial RNA safety concerns of E. coli produced influenza NP through CpG loaded mutant. NPJ Vaccines. 2025 Feb 15;10(1):32.  Abstract  
submitted by kickingbird at Feb, 17, 2025 from NPJ Vaccines. 2025 Feb 15;10(1):32 (via https://www.nature.com/articles/s41541-025-01087-z)
Influenza virus nucleoprotein (NP) is a promising target for universal influenza vaccines due to its conservation and high immunogenicity. Here, we uncovered a previously unknown factor that E. coli-produced ...

Briand, Francois-Xavier, Palumbo, Lo?c, Martenot,. Highly Pathogenic Clade 2.3.4.4b H5N1 Influenza Virus in Seabirds in France, 2022~2023. Transboundary and Emerging Diseases, 2025, 8895883.  Abstract  
submitted by kickingbird at Feb, 16, 2025 from Transboundary and Emerging Diseases, 2025, 8895883 (via https://onlinelibrary.wiley.com/doi/10.1155/tbed/8895883)
In 2022, a very high number of wild bird deaths associated with the detection of highly pathogenic (HP) H5 avian influenza virus (AIV) lineage Gs/GD/96, clade 2.3.4.4b viruses were unusually observed in ...

Quertermous BP, Williams DJ, Bruce J, Sekmen M, Zh. Serious Neurologic Events with Seasonal Influenza in Young Children. Acad Pediatr. 2025 Feb 12:102801.  Abstract  
submitted by kickingbird at Feb, 16, 2025 from Acad Pediatr. 2025 Feb 12:102801 (via https://www.academicpedsjnl.net/article/S1876-2859(25)00026-)
Objective: The objective of this study was to determine the population-based incidence of influenza-associated serious neurologic events in children Methods: We conducted a retrospective cohort of children ...

Kobayashi D, Hiono T, Arakawa H, Kaji H, Ohkawara. Deglycosylation and truncation in the neuraminidase stalk are functionally equivalent in enhancing the pathogenicity of a high pathogenicity avian influenza virus in chickens. J Virol. 2025 Feb 14:e0147824.  Abstract  
submitted by kickingbird at Feb, 15, 2025 from J Virol. 2025 Feb 14:e0147824 (via https://journals.asm.org/doi/10.1128/jvi.01478-24)
Influenza A viruses with fewer amino acids in the neuraminidase (NA) stalk domain are primarily isolated from chickens rather than wild ducks, indicating that a shortened NA stalk is considered an adaptation ...

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