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2019-12-8 0:57:57
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Chastagner A, Enouf V, Peroz D, et al. Bidirectional Human-Swine Transmission of Seasonal Influenza A(H1N1)pdm09 Virus in Pig Herd, France, 2018. Emerg Infect Dis. 2019;25(10):1940-1943.  Abstract  
submitted by kickingbird at Sep, 22, 2019 from Emerg Infect Dis. 2019;25(10):1940-1943 (via https://wwwnc.cdc.gov/eid/article/25/10/19-0068_article)
In 2018, a veterinarian became sick shortly after swabbing sows exhibiting respiratory syndrome on a farm in France. Epidemiologic data and genetic analyses revealed consecutive human-to-swine and swine-to-human ...

Wille M, Lisovski S, Risely A, et al. Serologic Evidence of Exposure to Highly Pathogenic Avian Influenza H5 Viruses in Migratory Shorebirds, Australia. Emerg Infect Dis. 2019;25(10):1903-1910.  Abstract  
submitted by kickingbird at Sep, 22, 2019 from Emerg Infect Dis. 2019;25(10):1903-1910 (via https://wwwnc.cdc.gov/eid/article/25/10/19-0699_article)
Highly pathogenic avian influenza (HPAI) H5Nx viruses of the goose/Guangdong/96 lineage continue to cause outbreaks in poultry and wild birds globally. Shorebirds, known reservoirs of avian influenza viruses, ...

Weese J, Anderson M, Berhane Y, et al. Emergence and Containment of Canine Influenza Virus A(H3N2), Ontario, Canada, 2017~2018. Emerg Infect Dis. 2019;25(10):1810-1816.  Abstract  
submitted by kickingbird at Sep, 22, 2019 from Emerg Infect Dis. 2019;25(10):1810-1816 (via https://wwwnc.cdc.gov/eid/article/25/10/19-0196_article)
Canine influenza virus (CIV) A(H3N2) was identified in 104 dogs in Ontario, Canada, during December 28, 2017~October 30, 2018, in distinct epidemiologic clusters. High morbidity rates occurred within groups ...

Bai R, et al. Antigenic Variation of Avian Influenza A(H5N6) Viruses, Guangdong Province, China, 2014-2018. Emerg Infect Dis. 2019 Oct;25(10):1932-1945.  Abstract  
submitted by kickingbird at Sep, 22, 2019 from Emerg Infect Dis. 2019 Oct;25(10):1932-1945 (via https://wwwnc.cdc.gov/eid/article/25/10/19-0274_article)
Market surveillance showed continuing circulation of avian influenza A(H5N6) virus in live poultry markets in Guangdong Province in 2017, despite compulsory vaccination for avian influenza A(H5Nx) and ...

Pohlmann A, et al. Genetic Characterization and Zoonotic Potential of Highly Pathogenic Avian Influenza Virus A(H5N6/H5N5), Germany, 2017-2018. Emerg Infect Dis. 2019 Oct;25(10):1973-1976..  Abstract  
submitted by kickingbird at Sep, 22, 2019 from Emerg Infect Dis. 2019 Oct;25(10):1973-1976. (via https://wwwnc.cdc.gov/eid/article/25/10/18-1931_article)
We genetically characterized highly pathogenic avian influenza virus A(H5N6) clade 2.3.4.4b isolates found in Germany in 2017-2018 and assessed pathogenicity of representative H5N5 and H5N6 viruses in ...

Sheng T, Sun Y, Sun J, Prinz RA, Peng D, et al. Role of TGF-β-activated kinase 1 (TAK1) activation in H5N1 influenza A virus-induced c-Jun terminal kinase activation and virus replication. Virology. 2019 Sep 10;537:263-271.  Abstract  
submitted by kickingbird at Sep, 22, 2019 from Virology. 2019 Sep 10;537:263-271 (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
Activation of c-Jun terminal kinase (JNK) by the nonstructural protein 1 (NS1) of the H5N1 subtype of influenza A virus (IAV) plays an important role in inducing autophagy and virus replication. However, ...

Hirotsu N, et al. Baloxavir marboxil in Japanese pediatric patients with influenza: safety and clinical and virologic outcomes. Clin Infect Dis. 2019 Sep 20..  Abstract  
submitted by kickingbird at Sep, 22, 2019 from Clin Infect Dis. 2019 Sep 20. (via https://academic.oup.com/cid/advance-article/doi/10.1093/cid)
BACKGROUND: We assessed the safety and effectiveness of baloxavir marboxil administration in Japanese children with influenza.METHODS: This open-label study administered one weigth-adjusted dose of baloxavir ...

Yu Z, Cheng K, He H, Wu J. A novel reassortant influenza A (H1N1) virus infection in swine in Shandong Province, eastern China. Transbound Emerg Dis. 2019 Sep 19..  Abstract  
submitted by kickingbird at Sep, 21, 2019 from Transbound Emerg Dis. 2019 Sep 19. (via https://onlinelibrary.wiley.com/doi/abs/10.1111/tbed.13360)
Influenza A (H1N1) viruses are distributed worldwide and pose a threat to public health. Swine, as a natural host and mixing vessel of influenza A (H1N1) virus, play a critical role in the transmission ...

Blackburn RM, et al. Nosocomial transmission of influenza: A retrospective cross-sectional study using next generation sequencing at a hospital in England (2012-2014). Influenza Other Respir Viruses. 2019 Sep 19.  Abstract  
submitted by kickingbird at Sep, 21, 2019 from Influenza Other Respir Viruses. 2019 Sep 19 (via https://onlinelibrary.wiley.com/doi/full/10.1111/irv.12679)
BACKGROUND: The extent of transmission of influenza in hospital settings is poorly understood. Next generation sequencing may improve this by providing information on the genetic relatedness of viral strains.OBJECTIVES: ...

Gao S, Zhang W, Lu C, Cao M, Cen S, Peng Y, Deng T. Identification of a type-specific promoter element that differentiates between influenza A and B viruses. J Virol. 2019 Sep 18.  Abstract  
submitted by kickingbird at Sep, 21, 2019 from J Virol. 2019 Sep 18 (via https://jvi.asm.org/content/early/2019/09/12/JVI.01164-19)
Type A and type B influenza viruses (FluA and FluB) are two major human pathogens that share common structural and functional features. FluA and FluB could reassort within each type but never between them. ...

Carter C, et al. Safety and immunogenicity of investigational seasonal influenza hemagglutinin DNA vaccine followed by trivalent inactivated vaccine administered intradermally or intramuscularly in healthy adults: An. PLoS One. 2019 Sep 18;14(9):e0222178..  Abstract  
submitted by kickingbird at Sep, 21, 2019 from PLoS One. 2019 Sep 18;14(9):e0222178. (via https://journals.plos.org/plosone/article?id=10.1371/journal)
BACKGROUND: Seasonal influenza results in significant morbidity and mortality worldwide, but the currently licensed inactivated vaccines generally have low vaccine efficacies and could be improved. In ...

Ma J, Yang N, Gu H, Bai L, Sun J, Gu S, Gu J. Effect of closure of live poultry markets in China on prevention and control of human infection with H7N9 avian influenza: a case study of four cities in Jiangsu Province. J Public Health Policy. 2019 Sep 16.  Abstract  
submitted by kickingbird at Sep, 21, 2019 from J Public Health Policy. 2019 Sep 16 (via https://link.springer.com/article/10.1057%2Fs41271-019-00185)
As of August 2017, China had encountered five seasonal epidemics of H7N9 avian influenza. To prevent people from contracting H7N9 avian influenza, most cities closed live poultry markets (LPMs) to cut ...

Ciminski K, et al. Bat influenza viruses transmit among bats but are poorly adapted to non-bat species. Nat Microbiol. 2019 Sep 16..  Abstract  
submitted by kickingbird at Sep, 21, 2019 from Nat Microbiol. 2019 Sep 16. (via https://www.nature.com/articles/s41564-019-0556-9)
Major histocompatibility complex class II (MHC-II) molecules of multiple species function as cell-entry receptors for the haemagglutinin-like H18 protein of the bat H18N11 influenza A virus, enabling tropism ...

Nemoto M, et al. Mutated influenza A virus exhibiting reduced susceptibility to baloxavir marboxil from an experimentally infected horse.. J Gen Virol. 2019 Sep 17..  Abstract  
submitted by kickingbird at Sep, 21, 2019 from J Gen Virol. 2019 Sep 17. (via https://www.ncbi.nlm.nih.gov/pubmed/31526451)
Baloxavir marboxil (BXM), an inhibitor of the cap-dependent endonuclease of the influenza virus polymerase acidic protein (PA), exerts an antiviral effect against influenza A virus. It has been available ...

Kandeil A, et al. Active surveillance and genetic evolution of avian influenza viruses in Egypt, 2016-2018. Emerg Microbes Infect. 2019;8(1):1370-1382.  Abstract  
submitted by kickingbird at Sep, 21, 2019 from Emerg Microbes Infect. 2019;8(1):1370-1382 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2019.1)
Egypt is a hotspot for avian influenza virus (AIV) due to the endemicity of H5N1 and H9N2 viruses. AIVs were isolated from 329 samples collected in 2016-2018; 48% were H9N2, 37.1% were H5N8, 7.6% were ...

H?nemann M, et al. Influenza B virus infections in Western Saxony, Germany in three consecutive seasons between 2015 and 2018: Analysis of molecular and clinical features. Vaccine. 2019 Sep 11..  Abstract  
submitted by kickingbird at Sep, 21, 2019 from Vaccine. 2019 Sep 11. (via https://www.sciencedirect.com/science/article/pii/S0264410X1)
BACKGROUND: The impact of annual influenza epidemics and prevailing strains varies worldwide and regional. The majority of vaccines used contained two influenza A strains and only one influenza B strain ...

Costantino V, Trent M, MacIntyre CR. Modelling of optimal timing for influenza vaccination as a function of intraseasonal waning of immunity and vaccine coverage. Vaccine. 2019 Sep 11.  Abstract  
submitted by kickingbird at Sep, 21, 2019 from Vaccine. 2019 Sep 11 (via https://www.sciencedirect.com/science/article/pii/S0264410X1)
The influenza season in Australia usually peaks in August. Vaccination is recommended beginning in March-April. Recent studies suggest that vaccine effectiveness may wane over a given influenza season, ...

Caini S, et al. The epidemiological signature of influenza B virus and its B/Victoria and B/Yamagata lineages in the 21st century. PLoS One. 2019 Sep 12;14(9):e0222381..  Abstract  
submitted by kickingbird at Sep, 14, 2019 from PLoS One. 2019 Sep 12;14(9):e0222381. (via https://journals.plos.org/plosone/article?id=10.1371/journal)
We describe the epidemiological characteristics, pattern of circulation, and geographical distribution of influenza B viruses and its lineages using data from the Global Influenza B Study. We included ...

Wang W, et al. Generation of a protective murine monoclonal antibody against the stem of influenza hemagglutinins from group 1 viruses and identification of resistance mutations against it. PLoS One. 2019 Sep 12;14(9):e0222436..  Abstract  
submitted by kickingbird at Sep, 14, 2019 from PLoS One. 2019 Sep 12;14(9):e0222436. (via https://journals.plos.org/plosone/article?id=10.1371/journal)
Vaccines that elicit broadly cross-neutralizing antibodies, including antibodies that target the conserved stem of hemagglutinin (HA), are being developed as a strategy for next-generation influenza vaccines ...

Youk S, et al. Rapid evolution of Mexican H7N3 highly pathogenic avian influenza viruses in poultry. PLoS One. 2019 Sep 12;14(9):e0222457..  Abstract  
submitted by kickingbird at Sep, 14, 2019 from PLoS One. 2019 Sep 12;14(9):e0222457. (via https://journals.plos.org/plosone/article?id=10.1371/journal)
Highly pathogenic avian influenza (HPAI) virus subtype H7N3 has been circulating in poultry in Mexico since 2012 and vaccination has been used to control the disease. In this study, eight Mexican H7N3 ...

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