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Graaf A, et al. A viral race for primacy: co-infection of a natural pair of low and highly pathogenic H7N7 avian influenza viruses in chickens and embryonated chicken eggs. Emerg Microbes Infect. 2018 Dec 5;7(1):204.  Abstract  
submitted by kickingbird at Dec, 9, 2018 from Emerg Microbes Infect. 2018 Dec 5;7(1):204 (via https://www.ncbi.nlm.nih.gov/pubmed/30514922)
Highly pathogenic avian influenza virus (HPAIV) infection in poultry caused devastating mortality and economic losses. HPAIV of subtypes H5 and H7 emerge from precursor viruses of low pathogenicity (LP) ...

Vahey MD, Fletcher DA. Low-Fidelity Assembly of Influenza A Virus Promotes Escape from Host Cells. Cell. 2018 Nov 27.  Abstract  
submitted by kickingbird at Dec, 9, 2018 from Cell. 2018 Nov 27 (via https://www.ncbi.nlm.nih.gov/pubmed/30503209)
Influenza viruses inhabit a wide range of host environments using a limited repertoire of protein components. Unlike viruses with stereotyped shapes, influenza produces virions with significant morphological ...

Zhang X, et al. Tissue tropisms opt for transmissible reassortants during avian and swine influenza A virus co-infection in swine. PLoS Pathog. 2018 Dec 3;14(12).  Abstract  
submitted by kickingbird at Dec, 9, 2018 from PLoS Pathog. 2018 Dec 3;14(12) (via https://www.ncbi.nlm.nih.gov/pubmed/30507946)
Genetic reassortment between influenza A viruses (IAVs) facilitate emergence of pandemic strains, and swine are proposed as a "mixing vessel" for generating reassortants of avian and mammalian IAVs that ...

He W, et al. Emergence and adaptation of H3N2 canine influenza virus from avian influenza virus: An overlooked role of dogs in interspecies transmission. Transbound Emerg Dis. 2018 Dec 6..  Abstract  
submitted by kickingbird at Dec, 9, 2018 from Transbound Emerg Dis. 2018 Dec 6. (via https://www.ncbi.nlm.nih.gov/pubmed/30520554)
H3N2 CIV originated from avian species and emerged in dogs in Asia around 2005 where it became enzootic before reaching the USA in 2015. To investigate the key aspects of the evolution of H3N2 CIV regarding ...

Tan KS, et al. Comparative Transcriptomic and Metagenomic Analyses of Influenza Virus-Infected Nasal Epithelial Cells From Multiple Individuals Reveal Specific Nasal-Initiated Signatures. Front Microbiol. 2018 Nov 14;9:2685.  Abstract  
submitted by kickingbird at Dec, 6, 2018 from Front Microbiol. 2018 Nov 14;9:2685 (via https://www.ncbi.nlm.nih.gov/pubmed/30487780)
In vitro and in vivo research based on cell lines and animals are likely to be insufficient in elucidating authentic biological and physiological phenomena mimicking human systems, especially for generating ...

Job ER, et al. Broadened immunity against influenza by vaccination with computationally designed influenza virus N1 neuraminidase constructs. NPJ Vaccines. 2018 Nov 29;3:55.  Abstract  
submitted by kickingbird at Dec, 6, 2018 from NPJ Vaccines. 2018 Nov 29;3:55 (via https://www.ncbi.nlm.nih.gov/pubmed/30510776)
Split inactivated influenza vaccines remain one of the primary preventative strategies against severe influenza disease in the population. However, current vaccines are only effective against a limited ...

Long JS, Mistry B, Haslam SM, Barclay WS. Host and viral determinants of influenza A virus species specificity. Nat Rev Microbiol. 2018 Nov 28.  Abstract  
submitted by kickingbird at Dec, 6, 2018 from Nat Rev Microbiol. 2018 Nov 28 (via https://www.nature.com/articles/s41579-018-0115-z)
Influenza A viruses cause pandemics when they cross between species and an antigenically novel virus acquires the ability to infect and transmit between these new hosts. The timing of pandemics is currently ...

Upadhyay BP, et al. Etiology of Coinfections in Children with Influenza during 2015/16 Winter Season in Nepal. Int J Microbiol. 2018 Oct 28;2018:8945142.  Abstract  
submitted by kickingbird at Dec, 6, 2018 from Int J Microbiol. 2018 Oct 28;2018:8945142 (via https://www.ncbi.nlm.nih.gov/pubmed/30510579)
Acute respiratory infections (ARIs) are one of the major public health problems in developing countries like Nepal. Besides the influenza, several other pathogens are responsible for acute respiratory ...

?van?arová P, Betáková T. Conserved methionine 165 of matrix protein contributes to the nuclear import and is essential for influenza A virus replication. Virol J. 2018 Dec 3;15(1):187.  Abstract  
submitted by kickingbird at Dec, 6, 2018 from Virol J. 2018 Dec 3;15(1):187 (via https://www.ncbi.nlm.nih.gov/pubmed/30509291)
BACKGROUND: The influenza matrix protein (M1) layer under the viral membrane plays multiple roles in virus assembly and infection. N-domain and C-domain are connected by a loop region, which consists of ...

Ampomah PB, et al. Annexins in Influenza Virus Replication and Pathogenesis. Front Pharmacol. 2018 Nov 15;9:1282.  Abstract  
submitted by kickingbird at Dec, 6, 2018 from Front Pharmacol. 2018 Nov 15;9:1282 (via https://www.ncbi.nlm.nih.gov/pubmed/30498445)
Influenza A viruses (IAVs) are important human respiratory pathogens which cause seasonal or periodic endemic infections. IAV can result in severe or fatal clinical complications including pneumonia and ...

Zhou J, et al. Identification and characterization of GLDC as host susceptibility gene to severe influenza. EMBO Mol Med. 2018 Nov 28..  Abstract  
submitted by kickingbird at Dec, 4, 2018 from EMBO Mol Med. 2018 Nov 28. (via https://www.ncbi.nlm.nih.gov/pubmed/30498026)
Glycine decarboxylase (GLDC) was prioritized as a candidate susceptibility gene to severe influenza in humans. The higher expression of GLDC derived from genetic variations may confer a higher risk to ...

Boyle CC, et al. Inflammation and dimensions of reward processing following exposure to the influenza vaccine. Psychoneuroendocrinology. 2018 Nov 20;102:16-23..  Abstract  
submitted by kickingbird at Dec, 4, 2018 from Psychoneuroendocrinology. 2018 Nov 20;102:16-23. (via https://www.ncbi.nlm.nih.gov/pubmed/30496908)
BACKGROUND: Alterations in reward processing are a central feature of depression and may be influenced by inflammation. Indeed, inflammation is associated with deficits in reward-related processes in animal ...

Sanyal M, et al. Diminished B-cell response after repeat influenza vaccination. J Infect Dis. 2018 Nov 28..  Abstract  
submitted by kickingbird at Dec, 4, 2018 from J Infect Dis. 2018 Nov 28. (via https://www.ncbi.nlm.nih.gov/pubmed/30496437)
Annual vaccination with influenza vaccines is recommended for protection against influenza in the United States. Past clinical studies and meta-analysis, however, have reported conflicting results on the ...

Chaimayo C, et al. Specificity and functional interplay between influenza virus PA-X and NS1 shutoff activity. PLoS Pathog. 2018 Nov 29;14(11):e1007465.  Abstract  
submitted by kickingbird at Dec, 4, 2018 from PLoS Pathog. 2018 Nov 29;14(11):e1007465 (via https://www.ncbi.nlm.nih.gov/pubmed/30496325)
Influenza A viruses modulate host antiviral responses to promote viral growth and pathogenicity. Through viral PA-X and NS1 proteins, the virus is capable of suppressing host protein synthesis, termed ...

Souza CK, et al. Serological surveillance and factors associated with influenza A virus in backyard pigs in Southern Brazil. Zoonoses Public Health. 2018 Nov 28.  Abstract  
submitted by kickingbird at Dec, 4, 2018 from Zoonoses Public Health. 2018 Nov 28 (via https://www.ncbi.nlm.nih.gov/pubmed/30485723)
Backyard pig populations are not monitored for influenza A virus (IAV) in Brazil and there are limited data about seroprevalence and risk factors in these populations. Our goal was to assess possible factors ...

Hagenaars TJ, et al. Risk of poultry compartments for transmission of Highly Pathogenic Avian Influenza. PLoS One. 2018 Nov 28;13(11):e0207076..  Abstract  
submitted by kickingbird at Dec, 4, 2018 from PLoS One. 2018 Nov 28;13(11):e0207076. (via https://www.ncbi.nlm.nih.gov/pubmed/30485292)
When outbreaks of Highly Pathogenic Avian Influenza (HPAI) occur in OIE member countries with until then disease-free status, member countries can use 'compartmentalisation'. A compartment may be defined ...

Landman WJM, Germeraad EA, Kense MJ. An avian influenza virus H6N1 outbreak in commercial layers: case report and reproduction of the disease. Avian Pathol. 2018 Nov 28:1-35..  Abstract  
submitted by kickingbird at Dec, 4, 2018 from Avian Pathol. 2018 Nov 28:1-35. (via https://www.ncbi.nlm.nih.gov/pubmed/30484684)
An outbreak of low pathogenic avian influenza (LPAI) subtype H6N1 (intravenous pathogenicity index?=?0.11) infection occurred in four productive brown layer flocks on three farms in the Netherlands within ...

Oladipo EK, Oloke JK, Adeniji JA. Intravenous pathogenicity of influenza virus A/H5N1/2014 isolated from pig in Ogbomoso, Nigeria. Open Vet J. 2018;8(3):347-350..  Abstract  
submitted by kickingbird at Dec, 4, 2018 from Open Vet J. 2018;8(3):347-350. (via https://www.ncbi.nlm.nih.gov/pubmed/30483460)
Understanding the pathogenicity of avian influenza viruses in poultry is an important scientific and public health challenge because of antigenic shift/drift and a source of novel, potentially human-pathogenic ...

Imai K, et al. Whole Genome Sequencing of Influenza A and B Viruses With the MinION Sequencer in the Clinical Setting: A Pilot Study. Front Microbiol. 2018 Nov 13;9:2748..  Abstract  
submitted by kickingbird at Dec, 4, 2018 from Front Microbiol. 2018 Nov 13;9:2748. (via https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6243006/)
Introduction: Whole genome sequencing (WGS) of influenza viruses is important for preparing vaccines and coping with newly emerging viruses. However, WGS is difficult to perform using conventional next-generation ...

Rimondi A, et al. Evidence of a fixed internal gene constellation in influenza A viruses isolated from wild birds in Argentina (2006-2016). Emerg Microbes Infect. 2018 Nov 28;7(1):194.  Abstract  
submitted by kickingbird at Dec, 4, 2018 from Emerg Microbes Infect. 2018 Nov 28;7(1):194 (via https://www.ncbi.nlm.nih.gov/pubmed/30482896)
Wild aquatic birds are the major reservoir of influenza A virus. Cloacal swabs and feces samples (n?=?6595) were collected from 62 bird species in Argentina from 2006 to 2016 and screened for influenza ...

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