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2020-1-23 22:05:44

Baranovskaya I, et al. Changes in RNA secondary structure affect NS1 protein expression during early stage influenza virus infection. Virol J. 2019 Dec 21;16(1):162..  Abstract  
submitted by kickingbird at Dec, 23, 2019 from Virol J. 2019 Dec 21;16(1):162. (via https://virologyj.biomedcentral.com/articles/10.1186/s12985-)
RNA secondary structures play a key role in splicing, gene expression, microRNA biogenesis, RNA editing, and other biological processes. The importance of RNA structures has been demonstrated in the life ...

Yao L, et al. Persistence of H7N9 virus antibody response 2 years after infection. Influenza Other Respir Viruses. 2019 Dec 19..  Abstract  
submitted by kickingbird at Dec, 21, 2019 from Influenza Other Respir Viruses. 2019 Dec 19. (via https://onlinelibrary.wiley.com/doi/full/10.1111/irv.12702)
We measured antibodies against H7N9 virus 2 years after infection in 14 patients who were infected during October 2016-September 2017. Approximately 2 years after infection, antibody titers ≥10 were detectable ...

Hassan KE, et al. Novel Reassortant Highly Pathogenic Avian Influenza A(H5N2) Virus in Broiler Chickens, Egypt. Emerg Infect Dis. 2020 Jan;26(1):129-133..  Abstract  
submitted by kickingbird at Dec, 21, 2019 from Emerg Infect Dis. 2020 Jan;26(1):129-133. (via https://wwwnc.cdc.gov/eid/article/26/1/19-0570_article)
We detected a novel reassortant highly pathogenic avian influenza A(H5N2) virus in 3 poultry farms in Egypt. The virus carried genome segments of a pigeon H9N2 influenza virus detected in 2014, a nucleoprotein ...

Chu DKW, et al. Influenza A Virus Infections in Dromedary Camels, Nigeria and Ethiopia, 2015-2017. Emerg Infect Dis. 2020 Jan;26(1):173-176.  Abstract  
submitted by kickingbird at Dec, 21, 2019 from Emerg Infect Dis. 2020 Jan;26(1):173-176 (via https://wwwnc.cdc.gov/eid/article/26/1/19-1165_article)
We examined nasal swabs and serum samples acquired from dromedary camels in Nigeria and Ethiopia during 2015-2017 for evidence of influenza virus infection. We detected antibodies against influenza A(H1N1) ...

Jiang W, et al. Antigenic Variant of Highly Pathogenic Avian Influenza A(H7N9) Virus, China, 2019. Emerg Infect Dis. 2020 Feb 17;26(2).  Abstract  
submitted by kickingbird at Dec, 21, 2019 from Emerg Infect Dis. 2020 Feb 17;26(2) (via https://wwwnc.cdc.gov/eid/article/26/2/19-1105_article)
In China, influenza A(H7N9) virus appeared in 2013, then mutated into a highly pathogenic virus, causing outbreaks among poultry and cases in humans. Since September 2017, extensive use of the corresponding ...

Murakami S, et al. Influenza D Virus of New Phylogenetic Lineage, Japan. Emerg Infect Dis. 2020 Jan;26(1):168-171..  Abstract  
submitted by kickingbird at Dec, 21, 2019 from Emerg Infect Dis. 2020 Jan;26(1):168-171. (via https://wwwnc.cdc.gov/eid/article/26/1/19-1092_article)
Influenza D virus (IDV) can potentially cause respiratory diseases in livestock. We isolated a new IDV strain from diseased cattle in Japan; this strain is phylogenetically and antigenically distinguished ...

Tepper V, et al. Influenza A/H4N2 mallard infection experiments further indicate zanamivir as less prone to induce environmental resistance development than oseltamivir. J Gen Virol. 2019 Dec 19.  Abstract  
submitted by kickingbird at Dec, 21, 2019 from J Gen Virol. 2019 Dec 19 (via https://www.microbiologyresearch.org/content/journal/jgv/10.)
Neuraminidase inhibitors (NAIs) are the gold standard treatment for influenza A virus (IAV). Oseltamivir is mostly used, followed by zanamivir (ZA). NAIs are not readily degraded in conventional wastewater ...

Jia R, Liu S, Xu J, Liang X. IL16 deficiency enhances Th1 and cytotoxic T lymphocyte response against influenza A virus infection. Biosci Trends. 2019 Dec 18.  Abstract  
submitted by kickingbird at Dec, 21, 2019 from Biosci Trends. 2019 Dec 18 (via https://www.jstage.jst.go.jp/article/bst/advpub/0/advpub_201)
Influenza A virus (IAV) is the major cause of seasonal epidemics and flu outbreaks worldwide. Given that interleukin 16 (IL16) can regulate T cell function and is one of the signature markers for virus ...

Abolnik C, Strydom C, Rauff DL, Wandrag DBR, Petty. Continuing evolution of H6N2 influenza a virus in South African chickens and the implications for diagnosis and control. BMC Vet Res. 2019 Dec 18;15(1):455..  Abstract  
submitted by kickingbird at Dec, 21, 2019 from BMC Vet Res. 2019 Dec 18;15(1):455. (via https://bmcvetres.biomedcentral.com/articles/10.1186/s12917-)
BACKGROUND: The threat of poultry-origin H6 avian influenza viruses to human health emphasizes the importance of monitoring their evolution. South Africa's H6N2 epidemic in chickens began in 2001 and two ...

Mu?oz-Moreno R, et al. Viral Fitness Landscapes in Diverse Host Species Reveal Multiple Evolutionary Lines for the NS1 Gene of Influenza A Viruses. Cell Rep. 2019 Dec 17;29(12):3997-4009.e5..  Abstract  
submitted by kickingbird at Dec, 21, 2019 from Cell Rep. 2019 Dec 17;29(12):3997-4009.e5. (via https://www.cell.com/cell-reports/fulltext/S2211-1247(19)315)
Influenza A viruses (IAVs) have a remarkable tropism in their ability to circulate in both mammalian and avian species. The IAV NS1 protein is a multifunctional virulence factor that inhibits the type ...

Li M, Feng S, Lv S, Luo J, Guo J, Sun J, He H. Highly pathogenic H5N6 avian influenza virus outbreak in Pavo cristatus in Jiangxi Province, China. Emerg Microbes Infect. 2019;8(1):377-380..  Abstract  
submitted by kickingbird at Dec, 21, 2019 from Emerg Microbes Infect. 2019;8(1):377-380. (via https://www.tandfonline.com/doi/full/10.1080/22221751.2019.1)
Highly pathogenic avian influenza (HPAI) is a persistent threat to poultry, wild birds, humans, and other mammals. The continually evolving HPAI H5N6 virus has induced great losses in breeding industries ...

Mohamed W, Ito K, Omori R. Estimating Transmission Potential of H5N1 Viruses Among Humans in Egypt Using Phylogeny, Genetic Distance and Sampling Time Interval. Front Microbiol. 2019 Dec 3;10:2765.  Abstract  
submitted by kickingbird at Dec, 21, 2019 from Front Microbiol. 2019 Dec 3;10:2765 (via https://www.frontiersin.org/articles/10.3389/fmicb.2019.0276)
In 2014 and 2015, the number of human cases of H5N1 avian influenza virus infections had increased dramatically in Egypt. This increase might be related to increase in the transmission potential of the ...

Li G, et al. Insulin-Like Growth Factor 1 Regulates Acute Inflammatory Lung Injury Mediated by Influenza Virus Infection. Front Microbiol. 2019 Nov 26;10:2541..  Abstract  
submitted by kickingbird at Dec, 21, 2019 from Front Microbiol. 2019 Nov 26;10:2541. (via https://www.frontiersin.org/articles/10.3389/fmicb.2019.0254)
The acute inflammatory lung injury is an important cause of death due to influenza A virus (IAV) infection. Insulin-like growth factor 1 (IGF1) played an important role in the regulation of inflammation ...

Li YT, et al. Avian influenza viruses in humans: lessons from past outbreaks. Br Med Bull. 2019 Dec 14.  Abstract  
submitted by kickingbird at Dec, 21, 2019 from Br Med Bull. 2019 Dec 14 (via https://academic.oup.com/bmb/advance-article-abstract/doi/10)
BACKGROUND: Human infections with avian influenza viruses (AIV) represent a persistent public health threat. The principal risk factor governing human infection with AIV is from direct contact with infected ...

Kuwahara T, Yamayoshi S, Noda T, Kawaoka Y. G Protein Pathway Suppressor 1 Promotes Influenza Virus Polymerase Activity by Activating the NF-κB Signaling Pathway. MBio. 2019 Dec 17;10(6). pii: e02867-19..  Abstract  
submitted by kickingbird at Dec, 21, 2019 from MBio. 2019 Dec 17;10(6). pii: e02867-19. (via https://mbio.asm.org/content/10/6/e02867-19)
Influenza virus relies heavily on cellular machinery to replicate in host cells. Therefore, to better understand the influenza virus life cycle, it is important to identify which host proteins are involved ...

Konstantinidi A, et al. The boundary lipid around DMPC-spanning influenza A M2 transmembrane domain channels: Its structure and potential for drug accommodation. Biochim Biophys Acta Biomembr. 2019 Dec 14:183156..  Abstract  
submitted by kickingbird at Dec, 21, 2019 from Biochim Biophys Acta Biomembr. 2019 Dec 14:183156. (via https://www.sciencedirect.com/science/article/pii/S000527361)
We have investigated the perturbation of influenza A M2TM in DMPC bilayers. We have shown that (a) DSC and SAXS detect changes in membrane organization caused by small changes (micromolar) in M2TM or aminoadamantane ...

Jureka AS, et al. The influenza NS1 protein modulates RIG-I activation via a strain-specific direct interaction with the second CARD of RIG-I. J Biol Chem. 2019 Dec 16..  Abstract  
submitted by kickingbird at Dec, 21, 2019 from J Biol Chem. 2019 Dec 16. (via http://www.jbc.org/content/early/2019/12/16/jbc.RA119.011410)
A critical role of the influenza A virus non-structural protein 1 (NS1) is to antagonize the host cellular antiviral response. NS1 accomplishes this role through numerous interactions with host proteins ...

McCarthy KR, et al. Affinity maturation in a human humoral response to influenza hemagglutinin. PNAS 2019 Dec 16.  Abstract  
submitted by kickingbird at Dec, 21, 2019 from PNAS 2019 Dec 16 (via https://www.ncbi.nlm.nih.gov/pubmed/31843892)
Affinity maturation of the B cell antigen receptor (BCR) is a conserved and crucial component of the adaptive immune response. BCR lineages, inferred from paired heavy- and light-chain sequences of rearranged ...

Nickbakhsh S, et al. Virus-virus interactions impact the population dynamics of influenza and the common cold. PNAS 2019 Dec 16.  Abstract  
submitted by kickingbird at Dec, 21, 2019 from PNAS 2019 Dec 16 (via https://www.pnas.org/content/early/2019/12/10/1911083116)
The human respiratory tract hosts a diverse community of cocirculating viruses that are responsible for acute respiratory infections. This shared niche provides the opportunity for virus-virus interactions ...

Virk RK, et al. Divergent evolutionary trajectories of influenza B viruses underlie their contemporaneous epidemic activity. PNAS 2019 Dec 16.  Abstract  
submitted by kickingbird at Dec, 21, 2019 from PNAS 2019 Dec 16 (via https://www.pnas.org/content/early/2019/12/13/1916585116)
Influenza B viruses have circulated in humans for over 80 y, causing a significant disease burden. Two antigenically distinct lineages ("B/Victoria/2/87-like" and "B/Yamagata/16/88-like," termed Victoria ...

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