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2019-9-22 10:58:51
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Ang JC, et al. Comparative Immunogenicity of the 2014-2015 Northern Hemisphere Trivalent IIV and LAIV against Influenza A Viruses in Children. Vaccines (Basel). 2019 Aug 12;7(3)..  Abstract  
submitted by kickingbird at Aug, 15, 2019 from Vaccines (Basel). 2019 Aug 12;7(3). (via https://www.mdpi.com/2076-393X/7/3/87)
Both inactivated influenza vaccines (IIV) and live-attenuated influenza vaccines (LAIV) have been recommended for administration to children. Children are a high-risk group for severe influenza, and a ...

Zhao Y, et al. Airborne transmission may have played a role in the spread of 2015 highly pathogenic avian influenza outbreaks in the United States. Sci Rep. 2019 Aug 13;9(1):11755..  Abstract  
submitted by kickingbird at Aug, 15, 2019 from Sci Rep. 2019 Aug 13;9(1):11755. (via https://www.nature.com/articles/s41598-019-47788-z)
The unprecedented 2015 outbreaks of highly pathogenic avian influenza (HPAI) H5N2 in the U.S. devastated its poultry industry and resulted in over $3 billion economic impacts. Today HPAI continues eroding ...

Biuso F, et al. Use of lentiviral pseudotypes as an alternative to reassortant or Triton X-100-treated wild-type Influenza viruses in the neuraminidase inhibition enzyme-linked lectin assay. Influenza Other Respir Viruses. 2019 Sep;13(5):504.  Abstract  
submitted by kickingbird at Aug, 15, 2019 from Influenza Other Respir Viruses. 2019 Sep;13(5):504 (via https://onlinelibrary.wiley.com/doi/full/10.1111/irv.12669)
BACKGROUND: Formulation of neuraminidase (NA) within influenza vaccines is gaining importance in light of recent human studies. The enzyme-linked lectin assay (ELLA) is considered a reliable assay to evaluate ...

Zhao P, et al. Semiaquatic mammals might be intermediate hosts to spread avian influenza viruses from avian to human. Sci Rep. 2019 Aug 12;9(1):11641.  Abstract  
submitted by kickingbird at Aug, 15, 2019 from Sci Rep. 2019 Aug 12;9(1):11641 (via https://www.nature.com/articles/s41598-019-48255-5)
Avian influenza A viruses (AIVs) can occasionally transmit to mammals and lead to the development of human pandemic. A species of mammal is considered as a mixing vessel in the process of host adaptation. ...

Hideshima S, et al. Glycan-immobilized dual-channel field effect transistor biosensor for the rapid identification of pandemic influenza viral particles. Sci Rep. 2019 Aug 12;9(1):11616.  Abstract  
submitted by kickingbird at Aug, 15, 2019 from Sci Rep. 2019 Aug 12;9(1):11616 (via https://www.nature.com/articles/s41598-019-48076-6)
Pandemic influenza, triggered by the mutation of a highly pathogenic avian influenza virus (IFV), has caused considerable damage to public health. In order to identify such pandemic IFVs, antibodies that ...

Dumm RE, Heaton NS. The Development and Use of Reporter Influenza B Viruses. Viruses. 2019 Aug 9;11(8)..  Abstract  
submitted by kickingbird at Aug, 15, 2019 from Viruses. 2019 Aug 9;11(8). (via https://www.mdpi.com/1999-4915/11/8/736)
Influenza B viruses (IBVs) are major contributors to total human influenza disease, responsible for ~1/3 of all infections. These viruses, however, are relatively less studied than the related influenza ...

De Vlugt C, Sikora D, Rocheleau L, Pelchat M. Priming and realignment by the influenza a virus RdRp is dependent on the length of the host primers and the extent of base pairing to viral RNA. Virology. 2019 Aug 2;536:91-100..  Abstract  
submitted by kickingbird at Aug, 15, 2019 from Virology. 2019 Aug 2;536:91-100. (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
Initiation of influenza A virus (IAV) transcription depends on RNA primers derived from host RNAs. During this process, some primers are elongated by a few nucleotides, realigned on the viral RNA templates ...

Lai CC, et al. Evaluation of novel disposable bioreactors on pandemic influenza virus production. PLoS One. 2019 Aug 12;14(8):e0220803..  Abstract  
submitted by kickingbird at Aug, 15, 2019 from PLoS One. 2019 Aug 12;14(8):e0220803. (via https://journals.plos.org/plosone/article?id=10.1371/journal)
Since 1997, the highly pathogenic influenza H5N1 virus has spread from Hong Kong. According to the WHO bulletin report, the H5N1 virus is a zoonotic disease threat that has infected more than 850 humans, ...

Xiong J, Zhao P, Yang P, Yan Q, Jiang L. Evolutionary dynamics of the H7N9 avian influenza virus based on large-scale sequence analysis. PLoS One. 2019 Aug 12;14(8):e0220249..  Abstract  
submitted by kickingbird at Aug, 15, 2019 from PLoS One. 2019 Aug 12;14(8):e0220249. (via https://journals.plos.org/plosone/article?id=10.1371/journal)
Since 2013, epidemics caused by novel H7N9 avian influenza A viruses (AIVs) have become a considerable public health issue. This study investigated the evolution of these viruses at the population level. ...

Khan S, et al. Use of an Influenza Antigen Microarray to Measure the Breadth of Serum Antibodies Across Virus Subtypes. J Vis Exp. 2019 Jul 26;(149)..  Abstract  
submitted by kickingbird at Aug, 15, 2019 from J Vis Exp. 2019 Jul 26;(149). (via https://www.jove.com/video/59973/use-an-influenza-antigen-mi)
The influenza virus remains a significant cause of mortality worldwide due to the limited effectiveness of currently available vaccines. A key challenge to the development of universal influenza vaccines ...

Li X, et al. Characterization of avian influenza H5N3 reassortants isolated from migratory waterfowl and domestic ducks in China from 2015 to 2018. Transbound Emerg Dis. 2019 Aug 11..  Abstract  
submitted by kickingbird at Aug, 15, 2019 from Transbound Emerg Dis. 2019 Aug 11. (via https://onlinelibrary.wiley.com/doi/abs/10.1111/tbed.13324)
Wild and domestic aquatic birds are the natural reservoirs of avian influenza viruses (AIVs). All subtypes of AIVs, including 16 hemagglutinin (HA) and nine neuraminidase (NA), have been isolated from ...

Trost JF, et al. A conserved histidine in Group-1 influenza subtype hemagglutinin proteins is essential for membrane fusion activity. Virology. 2019 Aug 6;536:78-90..  Abstract  
submitted by kickingbird at Aug, 15, 2019 from Virology. 2019 Aug 6;536:78-90. (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
Influenza A viruses enter host cells through the endocytic pathway, where acidification triggers conformational changes of the viral hemagglutinin (HA) to drive membrane fusion. During this process, the ...

Gouma S, Weirick M, Hensley SE. Potential antigenic mismatch of the H3N2 component of the 2019 Southern Hemisphere influenza vaccine. Clin Infect Dis. 2019 Aug 11..  Abstract  
submitted by kickingbird at Aug, 15, 2019 from Clin Infect Dis. 2019 Aug 11. (via https://academic.oup.com/cid/advance-article-abstract/doi/10)
Here, we find that the egg-adapted H3N2 component of the 2019 Southern Hemisphere influenza vaccine elicits an antibody response in ferrets that is highly focused on antigenic site A of hemagglutinin. ...

Ge Y, et al. The evolution and characterization of influenza A(H7N9) virus under the selective pressure of peramivir. Virology. 2019 Aug 6;536:58-67..  Abstract  
submitted by kickingbird at Aug, 15, 2019 from Virology. 2019 Aug 6;536:58-67. (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
Human infection with H7N9 virus has provoked global public health concern due to the substantial morbidity and mortality. Neuraminidase inhibitors (NAIs) are used as first-line drugs to treat the infection. ...

Garvey MI, et al. Lessons learnt from influenza POCT implementation in an AMU. J Hosp Infect. 2019 Aug 6.  Abstract  
submitted by kickingbird at Aug, 15, 2019 from J Hosp Infect. 2019 Aug 6 (via https://www.journalofhospitalinfection.com/article/S0195-670)
Influenza point of care tests (POCT) can speed up diagnosis and improve management of patients with influenza.1-3 Young et al discussed the impact of a POCT for influenza in an emergency department.4 The ...

Van Bennekom CM, Kerr SM, Mitchell AA. Oseltamivir exposure in pregnancy and the risk of specific birth defects. Birth Defects Res. 2019 Aug 8.  Abstract  
submitted by kickingbird at Aug, 11, 2019 from Birth Defects Res. 2019 Aug 8 (via https://onlinelibrary.wiley.com/doi/abs/10.1002/bdr2.1563)
BACKGROUND: Influenza during pregnancy contributes to maternal morbidity and mortality. Neuraminidase inhibitors, including oseltamivir, are recommended for treating women with influenza during pregnancy.METHODS: ...

Chambers CD, et al. Oseltamivir use in pregnancy: Risk of birth defects, preterm delivery, and small for gestational age infants. Birth Defects Res. 2019 Aug 8.  Abstract  
submitted by kickingbird at Aug, 11, 2019 from Birth Defects Res. 2019 Aug 8 (via https://onlinelibrary.wiley.com/doi/abs/10.1002/bdr2.1566)
BACKGROUND: Influenza infection during pregnancy increases risks for adverse outcomes for both mother and fetus. For this reason, treatment for infection or postexposure prophylaxis with a neuraminidase ...

Chang KH, et al. Gulllain-Barre Syndrome After Trivalent Influenza Vaccination in Adults. Front Neurol. 2019 Jul 24;10:768..  Abstract  
submitted by kickingbird at Aug, 11, 2019 from Front Neurol. 2019 Jul 24;10:768. (via https://www.frontiersin.org/articles/10.3389/fneur.2019.0076)
Lines of evidence suggest trivalent influenza vaccination may be associated with Guillain-Barre syndrome (GBS), an immune-mediated acute inflammatory neuropathy. On the other hand, this vaccination protects ...

Chang J, et al. octoFLU: Automated Classification for the Evolutionary Origin of Influenza A Virus Gene Sequences Detected in U.S. Swine. Microbiol Resour Announc. 2019 Aug 8;8(32)..  Abstract  
submitted by kickingbird at Aug, 11, 2019 from Microbiol Resour Announc. 2019 Aug 8;8(32). (via https://mra.asm.org/content/8/32/e00673-19)
The diversity of the 8 genes of influenza A viruses (IAV) in swine reflects introductions from nonswine hosts and subsequent antigenic drift and shift. Here, we curated a data set and present a pipeline ...

Palekar R, et al. Patterns of influenza B circulation in Latin America and the Caribbean, 2010~2017. PLoS One. 2019 Aug 8;14(8):e0219595.  Abstract  
submitted by kickingbird at Aug, 11, 2019 from PLoS One. 2019 Aug 8;14(8):e0219595 (via https://journals.plos.org/plosone/article?id=10.1371/journal)
OBJECTIVE: There are limited published data about the circulation of influenza B/Victoria and B/Yamagata in Latin America and the Caribbean (LAC) and most countries have a vaccine policy that includes ...

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