Ortigoza MB, Mobini CL, Rocha HL, Bartlett S, Loom. Inhibiting influenza virus transmission using a broadly acting neuraminidase that targets host sialic acids in the upper respiratory tract. mBio. 2024 Jan 11:e0220323. Abstract
submitted by kickingbird at Jan, 12, 2024 from mBio. 2024 Jan 11:e0220323 (via https://journals.asm.org/doi/10.1128/mbio.02203-23)
Influenza virus transmission studies have historically focused on viral mutations that alter hemagglutinin binding to sialic acid (SA) receptors in vitro. However, SA binding preference does not fully ... Lyashko AV, Timofeeva TA, Rudneva IA, Lomakina NF,. Antigenic Architecture of the H7N2 Influenza Virus Hemagglutinin Belonging to the North American Lineage. Int J Mol Sci. 2023 Dec 22;25(1):212. Abstract
submitted by kickingbird at Jan, 12, 2024 from Int J Mol Sci. 2023 Dec 22;25(1):212 (via https://www.mdpi.com/1422-0067/25/1/212)
The North American low pathogenic H7N2 avian influenza A viruses, which lack the 220-loop in the hemagglutinin (HA), possess dual receptor specificity for avian- and human-like receptors. The purpose of ... Si X, Wang L, Mengersen K, Hu W. Epidemiological features of seasonal influenza transmission among 11 climate zones in Chinese Mainland. Infect Dis Poverty. 2024 Jan 10;13(1):4. Abstract
submitted by kickingbird at Jan, 12, 2024 from Infect Dis Poverty. 2024 Jan 10;13(1):4 (via https://idpjournal.biomedcentral.com/articles/10.1186/s40249)
Background: Previous studies provided some evidence of meteorological factors influence seasonal influenza transmission patterns varying across regions and latitudes. However, research on seasonal influenza ... Maya-Badillo BA, Orta-Pineda G, Zavala-Vasco D, Ri. Influenza A virus antibodies in dogs, hunting dogs, and backyard pigs in Campeche, Mexico. Zoonoses Public Health. 2024 Jan 9. Abstract
submitted by kickingbird at Jan, 11, 2024 from Zoonoses Public Health. 2024 Jan 9 (via https://onlinelibrary.wiley.com/doi/10.1111/zph.13110)
Aims: This study aimed to identify exposure to human, swine, and avian influenza A virus subtypes in rural companion and hunting dogs, backyard pigs, and feral pigs.Methods and results: The study took ... Kayano T, Kobayashi T, Fujiwara S, Okada Y, Nishiu. Survey of exposure to stranded dolphins in Japan to investigate an outbreak of suspected infection with highly pathogenic avian influenza (H5N1) clade 2.3.4.4(b) in humans. New Microbes New Infect. 2023 Dec 16;56:101214. Abstract
submitted by kickingbird at Jan, 10, 2024 from New Microbes New Infect. 2023 Dec 16;56:101214 (via https://www.sciencedirect.com/science/article/pii/S205229752)
Background: A highly pathogenic avian influenza (HPAI) A (H5N1) virus has been detected in domestic and wild animals worldwide. The incidence of HPAI infections in sea mammals has been increasing, as is ... Jang SG, Kim YI, Casel MAB, Choi JH, Gil JR, Rollo. HA N193D substitution in the HPAI H5N1 virus alters receptor binding affinity and enhances virulence in mammalian hosts. Emerg Microbes Infect. 2024 Jan 8:2302854. Abstract
submitted by kickingbird at Jan, 9, 2024 from Emerg Microbes Infect. 2024 Jan 8:2302854 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2024.2)
During the 2021/2022 winter season, we isolated highly pathogenic avian influenza (HPAI) H5N1 viruses harboring an amino acid substitution from Asparagine(N) to Aspartic acid (D) at residue 193 of the ... Howard LM, Jensen TL, Goll JB, Gelber CE, Bradley. Metabolomic Signatures Differentiate Immune Responses in Avian Influenza Vaccine Recipients. J Infect Dis. 2024 Jan 5:jiad611. Abstract
submitted by kickingbird at Jan, 6, 2024 from J Infect Dis. 2024 Jan 5:jiad611 (via https://academic.oup.com/jid/advance-article-abstract/doi/10)
Background: Avian influenza viruses pose significant risk to human health. Vaccines targeting the hemagglutinin of these viruses are poorly immunogenic without the use of adjuvants.Methods: Twenty healthy ... Jin, K., Dai, Z., Shi, P. et al.. Severe pneumonia with co-infection of H5N1 and SARS-CoV-2: a case report. BMC Infect Dis 24, 31 (2024). Abstract
submitted by kickingbird at Jan, 6, 2024 from BMC Infect Dis 24, 31 (2024) (via https://bmcinfectdis.biomedcentral.com/articles/10.1186/s128)
BackgroundThe H5N1 influenza virus is a cause of severe pneumonia. Co-infection of influenza virus and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may lead to poor prognosis of patients ... Wang Q, Liu Z, Zeng X, Zheng Y, Lan L, Wang X, Lai. Integrated analysis of miRNA-mRNA expression of newly emerging swine H3N2 influenza virus cross-species infection with tree shrews. Virol J. 2024 Jan 4;21(1):4. Abstract
submitted by kickingbird at Jan, 5, 2024 from Virol J. 2024 Jan 4;21(1):4 (via https://virologyj.biomedcentral.com/articles/10.1186/s12985-)
Background: Cross-species transmission of zoonotic IAVs to humans is potentially widespread and lethal, posing a great threat to human health, and their cross-species transmission mechanism has attracted ... Elli S, Raffaini G, Guerrini M, Kosakovsky Pond S,. Molecular modeling and phylogenetic analyses highlight the role of amino acid 347 of the N1 subtype neuraminidase in influenza virus host range and interspecies adaptation. Front Microbiol. 2023 Dec 19;14:1309156. Abstract
submitted by kickingbird at Jan, 5, 2024 from Front Microbiol. 2023 Dec 19;14:1309156 (via https://www.frontiersin.org/articles/10.3389/fmicb.2023.1309)
The N1 neuraminidases (NAs) of avian and pandemic human influenza viruses contain tyrosine and asparagine, respectively, at position 347 on the rim of the catalytic site; the biological significance of ... Nu?ez IA, Jang H, Huang Y, Kelvin A, Ross TM. Influenza virus immune imprinting dictates the clinical outcomes in ferrets challenged with highly pathogenic avian influenza virus H5N1. Front Vet Sci. 2023 Dec 19;10:1286758. Abstract
submitted by kickingbird at Jan, 5, 2024 from Front Vet Sci. 2023 Dec 19;10:1286758 (via https://www.frontiersin.org/articles/10.3389/fvets.2023.1286)
Zoonotic transmission of H5N1 highly pathogenic avian influenza virus (HPAIV) into the human population is an increasing global threat. The recent 2022 HPAIV outbreak significantly highlighted this possibility, ... Hohensee L, Scheibner D, Sch?fer A, Shelton H, Met. The role of PB1-F2 in adaptation of high pathogenicity avian influenza virus H7N7 in chickens. Vet Res. 2024 Jan 3;55(1):5. Abstract
submitted by kickingbird at Jan, 5, 2024 from Vet Res. 2024 Jan 3;55(1):5 (via https://veterinaryresearch.biomedcentral.com/articles/10.118)
Avian influenza viruses (AIV) of the H7N7 subtype are enzootic in the wild bird reservoir in Europe, cause infections in poultry, and have sporadically infected humans. The non-structural protein PB1-F2 ... Chen X, Huang Y, Gao P, Wu F, Han Y, Zhang C, Hu Z. Engineering of novel hemagglutinin biosensors for rapid detection and drug screening of Influenza A H7N9 virus. Int J Biol Macromol. 2023 Dec 30:129126. Abstract
submitted by kickingbird at Jan, 3, 2024 from Int J Biol Macromol. 2023 Dec 30:129126 (via https://www.sciencedirect.com/science/article/abs/pii/S01418)
New pathogenic influenza virus strains are constantly emerging, posing a serious risk to both human health and economic growth. To effectively control the spread of this virus, there is an urgent need ... El-Kafrawy SA, Alsayed SM, Faizo AA, Bajrai LH, Ut. Genetic diversity and molecular analysis of human influenza virus among pilgrims during Hajj. Heliyon. 2023 Dec 2;10(1):e23027. Abstract
submitted by kickingbird at Jan, 3, 2024 from Heliyon. 2023 Dec 2;10(1):e23027 (via https://www.cell.com/heliyon/fulltext/S2405-8440(23)10235-0)
The risk of transmission of respiratory tract infections is considerably enhanced at mass gathering (MG) religious events. Hajj is an annual Islamic MG event with approximately 3 million Muslim pilgrims ... Tan M, Zeng X, Xie Y, Li X, Liu J, Yang J, Yang L,. Reported human infections of H9N2 avian influenza virus in China in 2021. Front Public Health. 2023 Dec 8;11:1255969. Abstract
submitted by kickingbird at Dec, 30, 2023 from Front Public Health. 2023 Dec 8;11:1255969 (via https://www.frontiersin.org/articles/10.3389/fpubh.2023.1255)
Introduction: The continued emergence of human infections of H9N2 avian influenza virus (AIV) poses a serious threat to public health. The prevalent Y280/G9 lineage of H9N2 AIV in Chinese poultry can directly ... Li H, Sun Z, Zheng T, Chen M, Lei X, Yu X, Ning Z. CD46 inhibits the replication of swine influenza viruses by promoting the production of type I IFNs in PK-15 cells. Vet Res Commun. 2023 Dec 28. Abstract
submitted by kickingbird at Dec, 29, 2023 from Vet Res Commun. 2023 Dec 28 (via https://link.springer.com/article/10.1007/s11259-023-10289-6)
Swine flu caused by swine influenza A virus (swIAV) is an acute respiratory viral disease that is spreading in swine herds worldwide. Although the effect of some host factors on replication of swIAV has ... Rashid F, Xie Z, Li M, Xie Z, Luo S, Xie L. Roles and functions of IAV proteins in host immune evasion. Front Immunol. 2023 Dec 13;14:1323560. Abstract
submitted by kickingbird at Dec, 28, 2023 from Front Immunol. 2023 Dec 13;14:1323560 (via https://www.frontiersin.org/articles/10.3389/fimmu.2023.1323)
Influenza A viruses (IAVs) evade the immune system of the host by several regulatory mechanisms. Their genomes consist of eight single-stranded segments, including nonstructural proteins (NS), basic polymerase ... Nguyen DT, Sumner KM, Nguyen TTM, Phan MQ, Hoang T. Avian influenza A(H5) virus circulation in live bird markets in Vietnam, 2017-2022. Influenza Other Respir Viruses. 2023 Dec;17(12):e1. Abstract
submitted by kickingbird at Dec, 28, 2023 from Influenza Other Respir Viruses. 2023 Dec;17(12):e1 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.13245)
Background: Highly pathogenic avian influenza A(H5) human infections are a global concern, with many A(H5) human cases detected in Vietnam, including a case in October 2022. Using avian influenza virus ... Finney J, Moseman AP, Kong S, Watanabe A, Song S,. Protective human antibodies against a conserved epitope in pre- and postfusion influenza hemagglutinin. Proc Natl Acad Sci U S A. 2024 Jan 2;121(1):e23169. Abstract
submitted by kickingbird at Dec, 27, 2023 from Proc Natl Acad Sci U S A. 2024 Jan 2;121(1):e23169 (via https://www.pnas.org/doi/10.1073/pnas.2316964120)
Phylogenetically and antigenically distinct influenza A and B viruses (IAV and IBV) circulate in human populations, causing widespread morbidity. Antibodies (Abs) that bind epitopes conserved in both IAV ... Daulagala P, Cheng SMS, Chin A, Luk LLH, Leung K,. Avian Influenza A(H5N1) Neuraminidase Inhibition Antibodies in Healthy Adults after Exposure to Influenza A(H1N1)pdm09. Emerg Infect Dis. 2024 Jan;30(1):168-171. Abstract
submitted by kickingbird at Dec, 27, 2023 from Emerg Infect Dis. 2024 Jan;30(1):168-171 (via https://wwwnc.cdc.gov/eid/article/30/1/23-0756_article)
We detected high titers of cross-reactive neuraminidase inhibition antibodies to influenza A(H5N1) virus clade 2.3.4.4b in 96.8% (61/63) of serum samples from healthy adults in Hong Kong in 2020. In contrast, ... 8178 items, 20/Page, Page[46/409][|<<] [|<] [41] [42] [43] [44] [45] [46] [47] [48] [49] [50] [>|] [>>|] |
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