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2024-5-18 23:22:54
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Parmley EJ, Bastien N, Booth TF, Bowes V, Buck PA,. Wild Bird Influenza Survey, Canada, 2005. Emerg Infect Dis. 2008 Jan.  Abstract  
submitted by kickingbird at Jan, 22, 2008 from Emerg Infect Dis. 2008 Jan (via http://www.cdc.gov/EID/content/14/1/84.htm)
AbstractOf 4,268 wild ducks sampled in Canada in 2005, real-time reverse transcriptase–PCR detected influenza A matrix protein (M1) gene sequence in 37% and H5 gene sequence in 5%. Mallards accounted for ...

WHO. Update on Avian Influenza A (H5N1) Virus Infection in Humans. NEJM.  Full Text  
submitted by kickingbird at Jan, 17, 2008 from NEJM (via http://content.nejm.org/cgi/content/full/358/3/261)
The unprecedented epizootic of avian influenza A (H5N1) viruses among birds continues to cause human disease with high mortality and to pose the threat of a pandemic. This review updates a 2005 report ...

Ngunjiri JM, Sekellick MJ, Marcus PI.. Clonogenic Assay of Type A Influenza Viruses Reveals Noninfectious Cell-Killing (Apoptosis-Inducing) Particlesa. J Virol. 2008 Jan 9.  Abstract  
submitted by kickingbird at Jan, 17, 2008 from J Virol. 2008 Jan 9 (via http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=Pub)
Clonogenic (single-cell plating) assays were used to define and quantify subpopulations of two genetically closely related variants of influenza virus A/TK/OR/71 that differed primarily in the size of ...

Anwar T, Khan AU.. Identification of a casein kinase II phosphorylation domain in NS1 protein of H5N1 influenza virus.. Bioinformation. 2007 Oct 3;2(2):57-61.  Full Text  
submitted by kickingbird at Jan, 15, 2008 from Bioinformation. 2007 Oct 3;2(2):57-61 (via http://www.ncbi.nlm.nih.gov/pubmed/18188421?ordinalpos=1&ito)
Influenza virus causes febrile respiratory illness. The infection results in significant mortality, morbidity and economic disruption. In this bioinformatics study, we used the NS1 (the conserved nonstructural) ...

Liao YC, Lee MS, Ko CY, Hsiung CA.. Bioinformatics models for predicting antigenic variants of influenza A/H3N2 virus. Bioinformatics. 2008 Jan 10.  Abstract  
submitted by kickingbird at Jan, 15, 2008 from Bioinformatics. 2008 Jan 10 (via http://www.ncbi.nlm.nih.gov/pubmed/18187440?ordinalpos=3&ito)
MOTIVATION: Continual and accumulated mutations in hemagglutinin (HA) protein of influenza A virus generate novel antigenic strains that cause annual epidemics. RESULTS: We propose a model by incorporating ...

Ng SS, Li OT, Cheung TK, Peiris JM, Poon LL. Heterologous influenza vRNA segments with identical non-coding sequences stimulate viral RNA replication in trans. Virol J. 2008 Jan 11;5(1):2.  Abstract  
submitted by kickingbird at Jan, 15, 2008 from Virol J. 2008 Jan 11;5(1):2 (via http://www.ncbi.nlm.nih.gov/pubmed/18186945?ordinalpos=4&ito)
ABSTRACT: The initiation of transcription and replication of influenza A virus requires the 5' and 3' ends of vRNA. Here, the role of segment-specific non-coding sequences of influenza A virus on viral ...

Wang Q, Cheng F, Lu M, Tian X, Ma J.. Crystal Structure of Unliganded Influenza B Virus Hemagglutinin. J Virol. 2008 Jan 9.  Abstract  
submitted by kickingbird at Jan, 15, 2008 from J Virol. 2008 Jan 9 (via http://www.ncbi.nlm.nih.gov/pubmed/18184701?ordinalpos=10&it)
Here we report the crystal structure of hemagglutinin (HA) from influenza B/HK/8/73 virus determined to 2.8 A. At a sequence identity of approximately 25% to influenza A virus HAs, B/HK HA shares a similar ...

Djikeng A, Halpin RA, Kuzmickas R, Depasse J, Feld. Viral genome sequencing by random priming methods. BMC Genomics. 2008 Jan 7;9(1):5.  Full Text  
submitted by kickingbird at Jan, 11, 2008 from BMC Genomics. 2008 Jan 7;9(1):5 (via http://www.ncbi.nlm.nih.gov/pubmed/18179705?ordinalpos=10&it)
Most emerging health threats are of zoonotic origin. For the overwhelming majority, their causative agents are RNA viruses which include but are not limited to HIV, Influenza, SARS, Ebola, Dengue, and ...

Mazur I, Anhlan D, Mitzner D, Wixler L, Schubert U. The proapoptotic influenza A virus protein PB1-F2 regulates viral polymerase activity by interaction with the PB1 protein. Cell Microbiol. 2008 Jan 7.  Abstract  
submitted by kickingbird at Jan, 11, 2008 from Cell Microbiol. 2008 Jan 7 (via http://www.ncbi.nlm.nih.gov/pubmed/18182088?ordinalpos=4&ito)
The 11(th) influenza A virus protein PB1-F2 was previously shown to enhance apoptosis in response to cytotoxic stimuli. The 87 amino acid protein that is encoded by an alternative reading frame of the ...

Aarthi Chandrasekaran, etc.,al. Glycan topology determines human adaptation of avian H5N1 virus hemagglutinin. Nature Biotechnology 26, 107 - 113 (2007).  Abstract  
submitted by kickingbird at Jan, 9, 2008 from Nature Biotechnology 26, 107 - 113 (2007) (via http://www.nature.com/nbt/journal/v26/n1/abs/nbt1375.html)
A switch in specificity of avian influenza A viruses' hemagglutinin (HA) from avian-like (2-3 sialylated glycans) to human-like (2-6 sialylated glycans) receptors is believed to be associated with their ...

Shen CH, Ge Q, Talay O, Eisen HN, García-Sastre A,. Loss of IL-7R and IL-15R Expression Is Associated with Disappearance of Memory T Cells in Respiratory Tract following Influenza Infection. J Immunol. 2008 Jan 1;180(1):171-8.  Abstract  
submitted by kickingbird at Jan, 9, 2008 from J Immunol. 2008 Jan 1;180(1):171-8 (via http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=Pub)
Following influenza virus infection, memory CD8 T cells are found in both lymphoid and nonlymphoid organs, where they exhibit striking differences in survival. We have assessed persistence, phenotype, ...

Zhou J, Matsuoka M, Cantor H, Homer R, Enelow RI.. Cutting Edge: Engagement of NKG2A on CD8+ Effector T Cells Limits Immunopathology in Influenza Pneumonia. J Immunol. 2008 Jan 1;180(1):25-9.  Abstract  
submitted by kickingbird at Jan, 9, 2008 from J Immunol. 2008 Jan 1;180(1):25-9 (via http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=Pub)
Influenza pneumonia results in considerable lung injury, a significant component of which is mediated by CD8(+) T cell Ag recognition in the distal airways and alveoli. TNF-alpha produced by Ag-specific ...

Itoh Y, Ozaki H, Tsuchiya H, Okamoto K, Torii R, S. A vaccine prepared from a non-pathogenic H5N1 avian influenza virus strain confers protective immunity against highly pathogenic avian influenza virus infection in cynomolgus macaques. Vaccine. 2007 Dec 3.  Abstract  
submitted by kickingbird at Jan, 7, 2008 from Vaccine. 2007 Dec 3 (via http://www.ncbi.nlm.nih.gov/pubmed/18164788?ordinalpos=25&it)
In order to prepare for the emergence of pandemic influenza viruses, we have established an influenza virus library that contains non-pathogenic influenza A virus strains with 135 combinations of 15 hemagglutinin ...

Heikkinen LS, Kazlauskas A, Melén K, Wagner R, Zie. Avian and 1918 Spanish influenza A virus NS1 proteins bind to Crk/CrkL SH3 domains to activate host cell signalling. J Biol Chem. 2007 Dec 28.  Abstract  
submitted by kickingbird at Jan, 7, 2008 from J Biol Chem. 2007 Dec 28 (via http://www.ncbi.nlm.nih.gov/pubmed/18165234?ordinalpos=24&it)
Nonstructural protein 1 (NS1) is an important virulence factor of the influenza A virus. We observed that NS1 proteins of the 1918 pandemic virus (A/Brevig Mission/1/18) and many avian influenza A viruses ...

Gabriel G, Garn H, Wegmann M, Renz H, Herwig A, Kl. The potential of a protease activation mutant of a highly pathogenic avian influenza virus for a pandemic live vaccine. Vaccine. 2007 Dec 10.  Abstract  
submitted by kickingbird at Jan, 7, 2008 from Vaccine. 2007 Dec 10 (via http://www.ncbi.nlm.nih.gov/pubmed/18164519?ordinalpos=26&it)
The most effective countermeasure against a pandemic originating from a highly pathogenic avian influenza virus (HPAIV) is immunoprophylaxis of the human population. We present here a new approach for ...

Zohari S, Gyarmati P, Thorén P, Czifra G, Br?jer C. Genetic characterization of the NS gene indicates co-circulation of two sub-lineages of highly pathogenic avian influenza virus of H5N1 subtype in Northern Europe in 2006. Virus Genes. 2008 Jan 3.  Abstract  
submitted by kickingbird at Jan, 7, 2008 from Virus Genes. 2008 Jan 3 (via http://www.ncbi.nlm.nih.gov/pubmed/18172752?ordinalpos=7&ito)
The non-structural (NS) gene of highly pathogenic avian influenza viruses of the H5N1 subtype (HPAI-H5N1) isolated in Baltic Sea area of Sweden in 2006 was studied. The phylogenetic analysis data demonstrated ...

Baras B, Stittelaar KJ, Simon JH, Thoolen RJ, Moss. Cross-Protection against Lethal H5N1 Challenge in Ferrets with an Adjuvanted Pandemic Influenza Vaccine. PLoS ONE. 2008 Jan 2;3(1):e1401.  Full Text  
submitted by kickingbird at Jan, 7, 2008 from PLoS ONE. 2008 Jan 2;3(1):e1401 (via http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pub)
BACKGROUND: Unprecedented spread between birds and mammals of highly pathogenic avian influenza viruses (HPAI) of the H5N1 subtype has resulted in hundreds of human infections with a high fatality rate. ...

Yang L, Wong CM, Lau EH, Chan KP, Ou CQ, Peiris JS. Synchrony of clinical and laboratory surveillance for influenza in Hong Kong. PLoS ONE. 2008 Jan 2;3(1):e1399.  Full Text  
submitted by kickingbird at Jan, 7, 2008 from PLoS ONE. 2008 Jan 2;3(1):e1399 (via http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pub)
BACKGROUND: Consultation rates of influenza-like illness (ILI) in an outpatient setting have been regarded as a good indicator of influenza virus activity in the community. As ILI-like symptoms may be ...

Lin JH, Tseng CP, Chen YJ, Lin CY, Chang SS, Wu HS. Rapid differentiation of influenza A virus subtypes and genetic screening for virus variants by high-resolution melting analysis. J Clin Microbiol. 2008 Jan 3.  Abstract  
submitted by kickingbird at Jan, 7, 2008 from J Clin Microbiol. 2008 Jan 3 (via http://www.ncbi.nlm.nih.gov/pubmed/18174299?ordinalpos=1&ito)
We assess the use of high-resolution melting (HRM) analysis for rapid identification of influenza A virus subtype and detection of newly emerging virus variant. The viral matrix gene was amplified by LightCycler ...

Sotirios Tsiodras, Theodoros Kelesidis,etc.,al. Human infections associated with wild birds. J Infect, published online Dec 21.  Abstract  
submitted by kickingbird at Dec, 29, 2007 from J Infect, published online Dec 21 (via http://www.journalofinfection.com/article/PIIS01634453070081)
Summary Introduction Wild birds and especially migratory species can become long-distance vectors for a wide range of microorganisms. The objective of the current paper is to summarize available literature ...

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