Lee K, Song D, Lyoo KS. Mammalian adaptation and zoonotic risk of influenza A viruses in companion animals. J Vet Sci. 2025 Nov;26(6):e80. Abstract submitted by kickingbird at 8 days ago from J Vet Sci. 2025 Nov;26(6):e80 (via https://vetsci.org/DOIx.php?id=10.4142/jvs.25153) Importance: Since the early 2000s, companion animals emerged as unexpected players in influenza A virus ecology. Canine influenza viruses and the increasing detection of highly pathogenic avian influenza ... Richard A. Neher, etc.,al. [preprint]Nomenclature for tracking of genetic variation of seasonal influenza viruses. https://doi.org/10.64898/2025.12.06.25341755. Abstract submitted by kickingbird at 8 days ago from https://doi.org/10.64898/2025.12.06.25341755 (via https://www.medrxiv.org/content/10.64898/2025.12.06.25341755) Background: Genomic surveillance of human seasonal influenza viruses is an essential component of the Global Influenza Surveillance and Response system (GISRS) and informs the recommendations for the seasonal ... Li, ZN., Liu, F., Jung, YJ. et al. Pre-existing cross-reactive immunity to highly pathogenic avian influenza 2.3.4.4b A(H5N1) virus in the United States. Nat Commun 16, 10954 (2025). Abstract submitted by kickingbird at 9 days ago from Nat Commun 16, 10954 (2025) (via https://link.springer.com/article/10.1038/s41467-025-66431-2) The unprecedented 2.3.4.4b. A(H5N1) outbreak in dairy cattle, poultry, and spillover to humans in the United States (US) poses a major public health threat. Population immunity is a critical component ... Son, SE., An, SH., Lee, CY. et al. Evolutionary trajectories and zoonotic potential of a PB2 mutation triad (I147T, K339T, and A588T) in avian influenza viruses. Vet Res (2025). Abstract submitted by kickingbird at 9 days ago from Vet Res (2025) (via https://link.springer.com/article/10.1186/s13567-025-01680-z) Efficient replication of influenza A viruses (IAVs) requires balanced activities of hemagglutinin (HA), neuraminidase (NA), and the RNA polymerase complex, whose functions are strongly influenced by PB2 ... Agustina Rimondi, etc.,al. [preprint]Persistence and spillback of mammal-adapted H5N1 genotype B3.2 viruses among South American seabirds and marine mammals. https://doi.org/10.21203/rs.3.rs-7960151/v1. Abstract submitted by kickingbird at 9 days ago from https://doi.org/10.21203/rs.3.rs-7960151/v1 (via https://www.researchsquare.com/article/rs-7960151/v1) The arrival of H5N1 clade 2.3.4.4b genotype B3.2 in South America marks an unprecedented geographic expansion of highly pathogenic avian influenza viruses. The continent remains the only region with sustained ... Wang, X., Zhang, X., Chen, C. et al. Comparison of efficacy, safety, immune response of dNS1 LAIV and cold-adapted LAIV in a mouse model. npj Vaccines (2025). Abstract submitted by kickingbird at 9 days ago from npj Vaccines (2025) (via https://link.springer.com/article/10.1038/s41541-025-01320-9) Influenza remains a significant global public health concern. Live-attenuated influenza vaccines (LAIVs) are recognized as effective interventions for influenza prevention. Currently, two types of LAIVs ... Douros A, Cui Y, Dell´Aniello S, Suissa S, B. Influenza Immunization at Midlife and the Risk of Parkinson Disease. JAMA Netw Open. 2025 Dec 1;8(12):e2547140. Abstract submitted by kickingbird at 9 days ago from JAMA Netw Open. 2025 Dec 1;8(12):e2547140 (via https://jamanetwork.com/journals/jamanetworkopen/fullarticle) Importance: Influenza infection could be associated with a long-term increase in the risk of Parkinson disease (PD). However, the benefit of influenza immunization as a preventive measure for PD remains ... Hu J, Li J, You W, Liu L, Chen H. Disruption of the local vRNA structure at the end of HA encoding region interferes with the selective packaging of influenza A virus genome. Biochem Biophys Res Commun. 2025 Dec 3;795:153082. Abstract submitted by kickingbird at 9 days ago from Biochem Biophys Res Commun. 2025 Dec 3;795:153082 (via https://www.sciencedirect.com/science/article/abs/pii/S00062) Influenza A virus (IAV) selectively packages eight distinct viral RNA (vRNA) segments into progeny virions through segment-specific packaging signals located in the noncoding regions and their adjacent ... Jin Y, Cui H, Jiang L, et al. From Surfaces to Spillover: Environmental Persistence and Indirect Transmission of Influenza A(H3N8) Virus. Microorganisms. 2025; 13(12):2782. Abstract submitted by kickingbird at 10 days ago from Microorganisms. 2025; 13(12):2782 (via https://www.mdpi.com/2076-2607/13/12/2782) Avian influenza viruses (AIVs) pose a significant zoonotic threat, with the emerging H3N8 subtype raising increasing concern due to sporadic human infections. Current strategies for risk assessment of ... David C. Brice, etc.,al. Immunogenicity and efficacy of commercial poultry avian influenza vaccines against HPAI A(H5N1) clade 2.3.4.4b viruses in Mexico. Virology. Abstract submitted by kickingbird at 10 days ago from Virology (via https://www.sciencedirect.com/science/article/abs/pii/S00426) The high-pathogenicity avian influenza A (H5N1) viruses of clade 2.3.4.4 b have been detected in domestic poultry and wild birds in Mexico. Vaccination with H5 vaccines has been implemented as a complementary ... Jingjing Zhang, etc.,al. Genomic and structural characterization of a reassortant H9N2 avian influenza virus from a human case. International Journal of Infectious Diseases. Abstract submitted by kickingbird at 10 days ago from International Journal of Infectious Diseases (via https://www.sciencedirect.com/science/article/pii/S120197122) BackgroundThe H9N2 subtype of avian influenza virus (AIV) is widely distributed in poultry and occasionally infects humans, posing a potential public health risk. While most infections are mild, severe ... Liedes, O., Reinholm, A., Ekstr?m, N. et al. Influenza A(H5N8) vaccine induces humoral and cell-mediated immunity against highly pathogenic avian influenza clade 2.3.4.4b A(H5N1) viruses in at-risk individuals. Nat Microbiol (2025). Abstract submitted by kickingbird at 11 days ago from Nat Microbiol (2025) (via https://www.nature.com/articles/s41564-025-02183-5) Finland faced an outbreak of highly pathogenic clade 2.3.4.4b A(H5N1) avian influenza in 2023, which spread from wild birds to fur farms. Vaccinations of at-risk individuals began in June 2024 using the ... Kephart, S.M., Awatramani, K.F., Saunders, M.I. et. Host switching mutations in H5N1 influenza hemagglutinin suppress site-specific activation dynamics. Nat Commun (2025). Abstract submitted by kickingbird at 11 days ago from Nat Commun (2025) (via https://link.springer.com/article/10.1038/s41467-025-66926-y) Increase in human H5N1 spillover infections resulting from dissemination of highly pathogenic avian influenza (HPAI) virus into bird and mammal populations raises concerns about HPAI gaining human transmissibility. ... Saubi N, Andrés C, Prats-Méndez I, González-Sánche. Expansion of influenza A(H1N1)pdm09 NA:S247N viruses with reduced susceptibility to oseltamivir, Catalonia, Spain, and in Europe, July to October 2025. Euro Surveill. 2025 Dec;30(48). Abstract submitted by kickingbird at 11 days ago from Euro Surveill. 2025 Dec;30(48) (via https://www.eurosurveillance.org/content/10.2807/1560-7917.E) Between July and October 2025, among the total 117 influenza A(H1N1)pdm09 strains characterised in Catalonia, 20% to 100% per week were carrying the NA:S247N substitution. The mutation, conferring reduced ... Harrell TL, Alvarez-Narvaez S, Porto-Fett ACS, Vin. Inactivation of avian influenza virus in yogurt made from raw milk. Food Microbiol. 2026 Apr;135:104975. Abstract submitted by kickingbird at 11 days ago from Food Microbiol. 2026 Apr;135:104975 (via https://www.sciencedirect.com/science/article/pii/S074000202) In March 2024, highly pathogenic avian influenza (HPAIV) H5N1 was first detected in U.S. dairy cattle and has since spread to herds across at least 17 states. Infected cows typically present with mastitis, ... Matyszewska D, Kapu?cińska M, Fontaine P. Elucidating the nature of the interactions of oseltamivir with the 2D model of influenza A virus lipid envelope. Colloids Surf B Biointerfaces. 2025 Nov 29;259:115. Abstract submitted by kickingbird at 11 days ago from Colloids Surf B Biointerfaces. 2025 Nov 29;259:115 (via https://www.sciencedirect.com/science/article/pii/S092777652) This study investigates the molecular interactions of the antiviral agent oseltamivir phosphate (OSL) with a two-dimensional (2D) Langmuir monolayer model of the influenza A (AH1N1) virus lipid envelope. ... Reeves C, Miura SST, Chappell AR, Banaag A, Coles. Trends in influenza vaccination uptake in a universally insured population in the united states, 2017-2023. Vaccine. 2025 Dec 3;71:128052. Abstract submitted by kickingbird at 11 days ago from Vaccine. 2025 Dec 3;71:128052 (via https://www.sciencedirect.com/science/article/abs/pii/S02644) Background: Annual vaccination against seasonal influenza is recommended for all persons ages ≥6 months in the U.S., as it is effective in reducing influenza-related illness and death. However, data show ... Qian Zhang, etc.,al. Autoantibodies neutralizing type I IFNs in a fatal case of H5N1 avian influenza. J Exp Med 2 March 2026; 223 (3): e20251962. Abstract submitted by kickingbird at 11 days ago from J Exp Med 2 March 2026; 223 (3): e20251962 (via https://rupress.org/jem/article/223/3/e20251962/278557/Autoa) Avian influenza A virus (IAV) H5N1 is an emerging threat of human pandemic. We describe a 71-year-old man who died of H5N1 pneumonia in Louisiana and whose blood contained autoantibodies neutralizing type ... An Y, Ding X, Tian Y, Zhang M, Ma Y, Wu X, Cai M,. High-throughput pseudovirus neutralisation maps the antigenic landscape of influenza A/H1N1 viruses. EBioMedicine. 2025 Dec 2;122:106047. Abstract submitted by kickingbird at 12 days ago from EBioMedicine. 2025 Dec 2;122:106047 (via https://www.thelancet.com/journals/ebiom/article/PIIS2352-39) Background: The continuous mutations in the haemagglutinin gene in A/H1N1 influenza viruses drives antigenic drift, necessitating frequent vaccine updates. Pseudovirus systems, with their flexible HA protein ... Huddleston J, Bedford T. Timely vaccine strain selection and genomic surveillance improve evolutionary forecast accuracy of seasonal influenza A/H3N2. Elife. 2025 Dec 4;14:RP104282. Abstract submitted by kickingbird at 12 days ago from Elife. 2025 Dec 4;14:RP104282 (via https://elifesciences.org/articles/104282) Evolutionary forecasting models inform seasonal influenza vaccine design by predicting which current genetic variants will dominate in the influenza season 12 months later. 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