Felipe Pe?a-Mosca, etc.,al. [preprint]The impact of influenza A H5N1 virus infection in dairy cows. https://doi.org/10.21203/rs.3.rs-6101018/v1
We investigated the impact of influenza A-H5N1 virus infection in a dairy herd. Clinical disease, which lasted for about three weeks, was recorded in 20.0% (777/3,876) of the adult cows. Milk losses of ~900 kg per cow were recorded in affected cows during a 60 day-post-outbreak period. Seroprevalence was 89.4% (570/637) in the herd, with 76.1% (485/637) of seropositive animals being subclinically infected. Clinically affected cows presented an increased risk of death (6 times) and of premature herd removal (3.6 times), when compared to non-clinical cows. Economic losses due to decreased milk production, mortality and early herd removal were estimated at $950 per clinically affected cow for a total cost of approximately $737,500 for the herd during the observation period. Our results demonstrate a long-lasting production impact and significant financial consequences of HPAI H5N1 virus infection to dairy farms.
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