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2026-9-21 21:31:14
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WPRO. Avian Influenza Weekly Update # 1062: 18 September 2026. WHO.  Abstract  
submitted by kickingbird at 8 hours ago from WHO (via https://cdn.who.int/media/docs/default-source/wpro---documen)
Avian influenza subtype A(HxNy) normally spreads in birds but can also infect humans. Human infections are primarily acquired through direct contact with infected poultry or contaminated environments. ...

Xie Y, Choi T, Al-Aly Z. Effectiveness of the 2025-2026 seasonal influenza vaccine among U.S. veterans: an observational study. EClinicalMedicine. 2026 Sep 10;100:104183.  Abstract  
submitted by kickingbird at 9 hours ago from EClinicalMedicine. 2026 Sep 10;100:104183 (via https://www.thelancet.com/journals/eclinm/article/PIIS2589-5)
Background: Annual vaccination is the primary strategy for preventing adverse clinical outcomes associated with seasonal influenza, but vaccine effectiveness varies by season with the degree of antigenic ...

Yujia Huang, etc.,al. Streamlined CRISPR-based assays for detection and subtyping of H5 and H7 avian influenza. iScience.  Abstract  
submitted by kickingbird at 2 days ago from iScience (via https://www.sciencedirect.com/science/article/pii/S258900422)
Avian influenza viruses (AIVs) are zoonotic pathogens that pose an increasing global threat due to their potential for significant economic losses in agriculture, and the risk of a pandemic should human-to-human ...

Ga, E., Xie, X., Hwang, J. et al. Host-specific effects of a pandemic H1N1 M gene on canine H3N2 influenza virus replication and immune responses. Sci Rep (2026).  Abstract  
submitted by kickingbird at 2 days ago from Sci Rep (2026) (via https://link.springer.com/article/10.1038/s41598-026-70452-2)
The emergence of novel influenza strains through reverse-zoonotic transmission poses potential risks to both animal and human health. This study characterized a naturally isolated reassortant canine H3N2 ...

Zeka E. Glucs, etc.,al. Rapid Decline of Nesting Peregrine Falcons in the San Francisco Bay Region of California Synchronous with an Outbreak of H5N1 Highly Pathogenic Avian Influenza. J. of Raptor Research, 60(3):1-11 (2026).  Abstract  
submitted by kickingbird at 2 days ago from J. of Raptor Research, 60(3):1-11 (2026) (via https://bioone.org/journals/journal-of-raptor-research/volum)
After rebounding from near extirpation during the organochlorine era, breeding Peregrine Falcons (Falco peregrinus, hereafter peregrines) in California are again facing adversity, this time consistent ...

Stephanie K. Lamb, etc.,al. Clinical Management of a Highly Pathogenic Avian Influenza H5N1 Outbreak in California Condors (Gymnogyps californianus) in Northern Arizona. Journal of Avian Medicine and Surgery.  Abstract  
submitted by kickingbird at 2 days ago from Journal of Avian Medicine and Surgery (via https://bioone.org/journals/journal-of-avian-medicine-and-su)
The California condor (Gymnogyps californianus) is a highly endangered scavenging bird that has been subject to many anthropogenic challenges in its free-living environment, including lead toxicosis, trash ...

Storms SM, Rathmann J, Hemker L, Vieson M, Wang L. Detection of Highly Pathogenic Avian Influenza A(H5N1) Virus in Cat and Rats during Outbreak in Backyard Poultry, United States, 2025. Emerg Infect Dis. 2026 Oct.  Abstract  
submitted by kickingbird at 3 days ago from Emerg Infect Dis. 2026 Oct (via https://wwwnc.cdc.gov/eid/article/32/10/26-0418_article)
In 2025, highly pathogenic avian influenza A(H5N1) virus was detected in a poultry flock in Illinois, USA. Quantitative reverse transcription PCR, sequencing, and histopathology on cat and rat samples ...

Wan Z, Jiang W, Cao X, Guo X, He X, Zhang J, Chu X. Novel emerging reassortant H6 avian influenza viruses with internal genes from G57 genotype of H9N2 pose potential zoonotic risk. Emerg Microbes Infect. 2026 Dec;15(1):2732846.  Abstract  
submitted by kickingbird at 3 days ago from Emerg Microbes Infect. 2026 Dec;15(1):2732846 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2026.2)
In recent decades, multiple novel reassortant avian influenza viruses (AIVs) carrying internal genes derived from H9N2 viruses have emerged in poultry in China and have repeatedly caused human infections, ...

Fan, M., Liu, Z., Deng, L. et al. LncFENIX restricts influenza A virus replication by impairing PDIA3-mediated oxidative folding of hemagglutinin. Cell Commun Signal (2026).  Abstract  
submitted by kickingbird at 3 days ago from Cell Commun Signal (2026) (via https://link.springer.com/article/10.1186/s12964-026-03228-w)
BackgroundInfluenza A virus (IAV) relies on host endoplasmic reticulum (ER) homeostasis machinery to support the oxidative folding and maturation of viral glycoproteins. Although long non-coding RNAs (lncRNAs) ...

McGinness, H.M., Jackson, M.V., King, D. et al. Environmental water management and H5 bird flu in waterbirds: context and scenarios for decision-making. Wetlands Ecol Manage 34, 84 (2026).  Abstract  
submitted by kickingbird at 3 days ago from Wetlands Ecol Manage 34, 84 (2026) (via https://link.springer.com/article/10.1007/s11273-026-10193-1)
The impact of animal viruses has dramatically increased over the last decade globally, exemplified by the disruption caused by the recent panzootic of high pathogenicity avian influenza (HPAI) H5N1 clade ...

Defaye B, Lamarque M, Moreau J, Gelle T, Imbert C,. Circulation of avian influenza viruses in migratory birds in Europe and in Africa: a systematic review. Emerg Microbes Infect. 2026 Dec;15(1):2728774.  Abstract  
submitted by kickingbird at 3 days ago from Emerg Microbes Infect. 2026 Dec;15(1):2728774 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2026.2)
Avian influenza virus (AIV) is an increasing driver of the emergence and re-emergence of outbreaks in both animal and human populations worldwide. Its circulation is influenced by migratory birds, human ...

Seibert, B.A., Parish, M.A., Talukdar, S.N. et al. Trimester-dependent vertical transmission of H5N1 influenza virus through placental and mammary routes impairs offspring development. Nat Commun 17, 9968 (2026).  Abstract  
submitted by kickingbird at 3 days ago from Nat Commun 17, 9968 (2026) (via https://www.nature.com/articles/s41467-026-76891-9)
Avian influenza H5N1 has pandemic potential and historically causes more severe disease in pregnant women than the general population. With increasing transmission of H5N1 detected among placental mammals, ...

Caroline Kikawa, etc.,al. [preprint]Near real-time data on the human neutralizing antibody landscape to influenza virus in summer of 2026 shows antigenic advance of H3N2 subclade K region D mutants and H1N1 D.3.1.1 Sa mutants. https://doi.org/10.64898/2026.09.15.751855.  Abstract  
submitted by kickingbird at 3 days ago from https://doi.org/10.64898/2026.09.15.751855 (via https://www.biorxiv.org/content/10.64898/2026.09.15.751855v1)
Human seasonal influenza evolves rapidly, necessitating twice yearly decisions about whether to update the strains in the vaccine. To help inform this decision, we have been using high-throughput sequencing-based ...

Elizabeth B White, Caroline A O’Neil, Melissa S St. Influenza mitigation recommendations, symptoms, and viral RNA shedding durations- 2023-24 and 2024-25 seasons. American Journal of Epidemiology, 2026.  Abstract  
submitted by kickingbird at 4 days ago from American Journal of Epidemiology, 2026 (via https://academic.oup.com/aje/advance-article-abstract/doi/10)
In March 2024, CDC released symptom-based isolation guidance for viral respiratory illnesses including influenza: isolation from others until fever-free for 24 hours and other symptoms are improving, followed ...

de Araujo J, Thomazelli LM, Fabrizio TP, Fenner GO. Detection of Divergent Highly Pathogenic Avian Influenza A(H5N1) Clade 2.3.4.4b Virus, Sao Paulo, Brazil, 2025. Emerg Infect Dis. 2026 Oct.  Abstract  
submitted by kickingbird at 4 days ago from Emerg Infect Dis. 2026 Oct (via https://wwwnc.cdc.gov/eid/article/32/10/26-0723_article)
In 2025, we detected highly pathogenic avian influenza H5N1 virus in dead waterfowl at Ibirapuera Park, S?o Paulo, Brazil. Genomic characterization indicated a reassortant virus that emerged from locally ...

Sch?n J, Breithaupt A, Halwe NJ, Hertel M, Ahrens. Experimental Highly Pathogenic Avian Influenza A(H5N1) Clade 2.3.4.4b Virus Infection in Alpacas, 2026. Emerg Infect Dis. 2026 Oct.  Abstract  
submitted by kickingbird at 4 days ago from Emerg Infect Dis. 2026 Oct (via https://wwwnc.cdc.gov/eid/article/32/10/26-0491_article)
Highly pathogenic avian influenza (HPAI) A(H5N1) clade 2.3.4.4b virus continues to spread globally and sporadically transmits from avian reservoirs to mammalian hosts. In May 2024, H5N1 infections in young ...

Byrne AMP, Carnegie L, Lewis NS, Barr IG, Karlsson. Reassortment of Highly Pathogenic Avian Influenza as a Driver for Zoonotic Spillover, Asia. Emerg Infect Dis. 2026 Oct.  Abstract  
submitted by kickingbird at 4 days ago from Emerg Infect Dis. 2026 Oct (via https://wwwnc.cdc.gov/eid/article/32/10/26-0067_article)
Highly pathogenic avian influenza H5Nx viruses remain a major zoonotic threat, yet global attention has focused largely on clade 2.3.4.4b, potentially overlooking major changes within long-endemic H5N1 ...

Yang J, Chen C, Zhang Z, Li J, Cui W, Jiang Y, Wan. Genetic Characteristics and Pathogenicity of Recent G4 Eurasian Avian-like H1N1 Swine Influenza Viruses in China. Veterinary Sciences. 2026; 13(9):936.  Abstract  
submitted by kickingbird at 5 days ago from Veterinary Sciences. 2026; 13(9):936 (via https://www.mdpi.com/2306-7381/13/9/936)
G4 Eurasian avian-like H1N1 (G4 EA-H1N1) swine influenza viruses continue to be detected in pigs in China and remain a concern because of their reassortant genomes and zoonotic potential. Here, six H1N1 ...

Augustyniak A, Czy?ewska-Dors E, ?agowski D, Domań. Clinical Course, Laboratory Findings, and Tissue Distribution of Highly Pathogenic Avian Influenza A(H5N1) Virus in a Naturally Infected Domestic Cat. Viruses. 2026; 18(9):1031.  Abstract  
submitted by kickingbird at 5 days ago from Viruses. 2026; 18(9):1031 (via https://www.mdpi.com/1999-4915/18/9/1031)
In June 2023, Poland experienced an unprecedented outbreak of highly pathogenic avian influenza (HPAI) H5N1 virus infections in cats, raising concerns about the role of cats in HPAI H5N1 virus ecology ...

Gabiden A, Mutaliyeva A, Usserbayev A, Yermekbayev. Antigenic and Molecular Genetic Evolution of Influenza Viruses in Kazakhstan from 2017 to 2025. Biology. 2026; 15(18):1640.  Abstract  
submitted by kickingbird at 5 days ago from Biology. 2026; 15(18):1640 (via https://www.mdpi.com/2079-7737/15/18/1640)
Influenza viruses continuously evolve, which can change their circulation patterns and reduce recognition by existing immunity and vaccine-induced antibodies. Continuous surveillance is therefore important ...

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