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2024-3-19 11:01:13
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Pulit-Penaloza JA, Brock N, Belser JA, Sun X, Papp. Highly pathogenic avian influenza A(H5N1) virus of clade 2.3.4.4b isolated from a human case in Chile causes fatal disease and transmits between co-housed ferrets. Emerg Microbes Infect. 2024 Mar 17:2332667.  Abstract  
submitted by kickingbird at 14 hours ago from Emerg Microbes Infect. 2024 Mar 17:2332667 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2024.2)
Clade 2.3.4.4b highly pathogenic avian influenza A(H5N1) viruses have caused large outbreaks within avian populations on five continents, with concurrent spillover into a variety of mammalian species. ...

Domnich A, Orsi A, Signori A, Chironna M, Manini I. Waning intra-season vaccine effectiveness against influenza A(H3N2) underlines the need for more durable protection. Expert Rev Vaccines. 2024 Jan-Dec;23(1):380-388.  Abstract  
submitted by kickingbird at 14 hours ago from Expert Rev Vaccines. 2024 Jan-Dec;23(1):380-388 (via https://www.tandfonline.com/doi/full/10.1080/14760584.2024.2)
Background: The question of whether influenza vaccine effectiveness (VE) wanes over the winter season is still open and some contradictory findings have been reported. This study investigated the possible ...

Leung RC, Ip JD, Chen LL, Chan WM, To KK. Global emergence of neuraminidase inhibitor-resistant influenza A(H1N1)pdm09 viruses with I223V and S247N mutations: implications for antiviral resistance monitoring. Lancet Microbe. 2024 Mar 14:S2666-5247(24)00037-5.  Abstract  
submitted by kickingbird at 22 hours ago from Lancet Microbe. 2024 Mar 14:S2666-5247(24)00037-5 (via https://www.thelancet.com/journals/lanmic/article/PIIS2666-5)
Neuraminidase inhibitors (NAIs), such as oseltamivir and zanamivir, serve as the primary treatment for influenza virus infection. NAI-resistant influenza A(H1N1) strains were widespread during the 2008–09 ...

Song W, Zhao L, Liu S, Jia Y, Ma L, Liao M, Dai M. Analysis of H5N8 influenza virus infection in chicken with mApple reporter genes in vivo and in vitro. Vet Microbiol. 2024 Mar 11;292:110052.  Abstract  
submitted by kickingbird at 22 hours ago from Vet Microbiol. 2024 Mar 11;292:110052 (via https://www.sciencedirect.com/science/article/abs/pii/S03781)
H5N8 highly pathogenic avian influenza virus (HPAIV) has caused huge losses to the global poultry industry and critically threatens public health. Chickens are the important host for the transmission. ...

Lagan P, Hamil M, Cull S, Hanrahan A, Wregor RM, L. Swine influenza A virus infection dynamics and evolution in intensive pig production systems. Virus Evol. 2024 Feb 27;10(1):veae017.  Abstract  
submitted by kickingbird at 3 days ago from Virus Evol. 2024 Feb 27;10(1):veae017 (via https://academic.oup.com/ve/article/10/1/veae017/7615508)
Swine influenza A virus (swIAV) is one of the main viral pathogens responsible for respiratory disease in farmed pigs. While outbreaks are often epidemic in nature, increasing reports suggest that continuous, ...

Schmidt K, Ben Moussa M, Buckrell S, Rahal A, Ches. National Influenza Annual Report, Canada, 2022-2023: Canada´s first fall epidemic since the 2019-2020 season. Can Commun Dis Rep. 2023 Oct 1;49(10):413-424.  Abstract  
submitted by kickingbird at 3 days ago from Can Commun Dis Rep. 2023 Oct 1;49(10):413-424 (via https://www.canada.ca/content/dam/phac-aspc/documents/servic)
Coinciding with the beginning of the coronavirus disease 2019 (COVID-19) pandemic in March 2020, Canadian seasonal influenza circulation was suppressed, which was a trend reported globally. Canada saw ...

Kim HJ, Han CW, Jeong MS, Jang SB. Cryo-EM structure of Influenza A virus NS1 and antiviral protein kinase PKR complex. Biochem Biophys Res Commun. 2024 Mar 5;706:149728.  Abstract  
submitted by kickingbird at 3 days ago from Biochem Biophys Res Commun. 2024 Mar 5;706:149728 (via https://www.sciencedirect.com/science/article/abs/pii/S00062)
Influenza A virus is the cause of a widespread human disease with high morbidity and mortality rates. The influenza virus encodes non-structural protein 1 (NS1), an exceedingly multifunctional virulence ...

Arruda B, Baker ALV, Buckley A, Anderson TK, Torch. Divergent Pathogenesis and Transmission of Highly Pathogenic Avian Influenza A(H5N1) in Swine. Emerg Infect Dis. 2024 Mar 13;30(4).  Abstract  
submitted by kickingbird at 4 days ago from Emerg Infect Dis. 2024 Mar 13;30(4) (via https://pubmed.ncbi.nlm.nih.gov/38478379/)
Highly pathogenic avian influenza (HPAI) viruses have potential to cross species barriers and cause pandemics. Since 2022, HPAI A(H5N1) belonging to the goose/Guangdong 2.3.4.4b hemagglutinin phylogenetic ...

Heindl MR, Rupp A-L, Schwerdtner M, Bestle D, Harb. ACE2 acts as a novel regulator of TMPRSS2-catalyzed proteolytic activation of influenza A virus in airway cells. J Virol. 2024 Mar 12:e0010224.  Abstract  
submitted by kickingbird at 6 days ago from J Virol. 2024 Mar 12:e0010224 (via https://journals.asm.org/doi/10.1128/jvi.00102-24)
The transmembrane serine protease 2 (TMPRSS2) activates the outer structural proteins of a number of respiratory viruses including influenza A virus (IAV), parainfluenza viruses, and various coronaviruses ...

Spruit CM, Palme DI, Li T, Ríos Carrasco M, Gabarr. Complex N-glycans are important for interspecies transmission of H7 influenza A viruses. J Virol. 2024 Mar 12:e0194123.  Abstract  
submitted by kickingbird at 6 days ago from J Virol. 2024 Mar 12:e0194123 (via https://journals.asm.org/doi/10.1128/jvi.01941-23)
Influenza A viruses (IAVs) can overcome species barriers by adaptation of the receptor-binding site of the hemagglutinin (HA). To initiate infection, HAs bind to glycan receptors with terminal sialic acids, ...

Larbi I, Marwa A, Souai O, Tougorti H, Butcher GD,. Phylogeographic Dynamics of H9N2 Avian Influenza Viruses in Tunisia. Virus Res. 2024 Mar 9:199348.  Abstract  
submitted by kickingbird at 6 days ago from Virus Res. 2024 Mar 9:199348 (via https://pubmed.ncbi.nlm.nih.gov/38467378/)
Avian influenza virus subtype H9N2 is endemic in commercial poultry in Tunisia. This subtype affects poultry and wild birds in Tunisia and poses a potential zoonotic risk. Tunisian H9N2 strains carry, ...

Wen F, Yan Z, Chen G, Chen Y, Wang N, Li Z, Guo J,. Recent H9N2 avian influenza virus lost hemagglutination activity due to a K141N substitution in hemagglutinin. J Virol. 2024 Mar 11:e0024824.  Abstract  
submitted by kickingbird at 7 days ago from J Virol. 2024 Mar 11:e0024824 (via https://journals.asm.org/doi/10.1128/jvi.00248-24)
The H9N2 avian influenza virus (AIV) represents a significant risk to both the poultry industry and public health. Our surveillance efforts in China have revealed a growing trend of recent H9N2 AIV strains ...

Plaza PI, Gamarra-Toledo V, Rodríguez Euguí J, Ros. Pacific and Atlantic sea lion mortality caused by highly pathogenic Avian Influenza A(H5N1) in South America. Travel Med Infect Dis. 2024 Mar 8:102712.  Abstract  
submitted by kickingbird at 8 days ago from Travel Med Infect Dis. 2024 Mar 8:102712 (via https://www.sciencedirect.com/science/article/pii/S147789392)
We describe the evolution of the outbreak of Highly Pathogenic Avian Influenza (HPAI) A(H5N1) in sea lions (Otaria flavescens) of South America. At least 24,000 sea lions died in Peru, Chile, Argentina, ...

Koutsakos M, Rockman S, Krammer F. Is eradication of influenza B viruses possible?. Lancet Infect Dis. 2024 Mar 4:S1473-3099(24)00132-.  Abstract  
submitted by kickingbird at 9 days ago from Lancet Infect Dis. 2024 Mar 4:S1473-3099(24)00132- (via https://www.thelancet.com/journals/laninf/article/PIIS1473-3)
Influenza B virus infections account for a substantial proportion of cases of influenza annually, with a high morbidity and mortality burden, especially in children (aged 0–18 years). Influenza B virus, ...

Kim JY, Jeong S, Kim DW, Lee DW, Lee DH, Kim D, Kw. Genomic epidemiology of highly pathogenic avian influenza A (H5N1) virus in wild birds in South Korea during 2021-2022: Changes in viral epidemic patterns. Virus Evol. 2024 Feb 7;10(1):veae014..  Abstract  
submitted by kickingbird at 9 days ago from Virus Evol. 2024 Feb 7;10(1):veae014. (via https://academic.oup.com/ve/article/10/1/veae014/7606456)
Clade 2.3.4.4b highly pathogenic avian influenza A (HPAI) viruses have been detected in wild birds worldwide, causing recurrent outbreaks since 2016. During the winter of 2021-2022, we detected one H5N8 ...

Mao Q, Li Z, Li Y, Zhang Y, Liu S, Yin X, Peng C,. H5N1 high pathogenicity avian influenza virus in migratory birds exhibiting low pathogenicity in mallards increases its risk of transmission and spread in poultry. Vet Microbiol. 2024 Mar 2;292:110038.  Abstract  
submitted by kickingbird at 9 days ago from Vet Microbiol. 2024 Mar 2;292:110038 (via https://www.sciencedirect.com/science/article/abs/pii/S03781)
In 2020, an H5N1 avian influenza virus of clade 2.3.4.4b was detected in Europe for the first time and was spread throughout the world by wild migratory birds, resulting in the culling of an unprecedented ...

Lim WW, Shuo F, Wong SS, Sullivan SG, Cowling BJ. Hemagglutination inhibition antibody titers mediate influenza vaccine efficacy against symptomatic influenza A(H1N1), A(H3N2), and B/Victoria infections. J Infect Dis. 2024 Mar 7:jiae122.  Abstract  
submitted by kickingbird at 11 days ago from J Infect Dis. 2024 Mar 7:jiae122 (via https://academic.oup.com/jid/advance-article-abstract/doi/10)
Background: The hemagglutination inhibition antibody (HAI) titer mediates only a part of vaccine-induced protection against influenza virus infections. Using causal mediation analysis, we quantified the ...

Tapia R, Brito B, Saavedra M, Mena J, García-Salum. Novel influenza A viruses in pigs with zoonotic potential, Chile. Microbiol Spectr. 2024 Mar 6:e0218123.  Abstract  
submitted by kickingbird at 12 days ago from Microbiol Spectr. 2024 Mar 6:e0218123 (via https://journals.asm.org/doi/10.1128/spectrum.02181-23)
Novel H1N2 and H3N2 swine influenza A viruses (IAVs) have recently been identified in Chile. The objective of this study was to evaluate their zoonotic potential. We perform phylogenetic analyses to determine ...

Tan M, Zhang Y, Bo H, Li X, Zou S, Yang L, Liu J,. Rapid adaptive substitution of L226Q in HA protein increases the pathogenicity of H9N2 viruses in mice. Infect Med (Beijing). 2024 Feb 13;3(1):100090.  Abstract  
submitted by kickingbird at 12 days ago from Infect Med (Beijing). 2024 Feb 13;3(1):100090 (via https://www.sciencedirect.com/science/article/pii/S2772431X2)
Background: Since the first human infection with H9N2 virus was reported in 1998, the number of cases of H9N2 infection has exceeded one hundred by 2021. However, there is no systematic description of ...

Sanogo IN, Guinat C, Dellicour S, Diakité MA, Nian. Genetic insights of H9N2 avian influenza viruses circulating in Mali and phylogeographic patterns in Northern and Western Africa. Virus Evol. 2024 Feb 19;10(1):veae011.  Abstract  
submitted by kickingbird at 13 days ago from Virus Evol. 2024 Feb 19;10(1):veae011 (via https://academic.oup.com/ve/article/10/1/veae011/7610485)
Avian influenza viruses (AIVs) of the H9N2 subtype have become widespread in Western Africa since their first detection in 2017 in Burkina Faso. However, the genetic characteristics and diffusion patterns ...

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