J?rhult JD, Muradrasoli S, Wahlgren J, S?derstr?m. Environmental Levels of the Antiviral Oseltamivir Induce Development of Resistance Mutation H274Y in Influenza A/H1N1 Virus in Mallards. PLoS ONE 6(9): e24742. doi:10.1371/journal.pone.00. Abstract
submitted by kickingbird at Sep, 20, 2011 from PLoS ONE 6(9): e24742. doi:10.1371/journal.pone.00 (via http://www.plosone.org/article/info:doi/10.1371/journal.pone)
Oseltamivir (Tamiflu?) is the most widely used drug against influenza infections and is extensively stockpiled worldwide as part of pandemic preparedness plans. However, resistance is a growing problem ... Gregory C. Gray, etc.,al. Evidence for Subclinical Avian Influenza Virus Infections Among Rural Thai Villagers. Clin Infect Dis. (2011) 53 (8): e107-e116.. Full Text
submitted by kickingbird at Sep, 17, 2011 from Clin Infect Dis. (2011) 53 (8): e107-e116. (via http://cid.oxfordjournals.org/content/53/8/e107.full)
Background.?Regions of Thailand reported sporadic outbreaks of A/H5N1 highly pathogenic avian influenza (HPAI) among poultry between 2004 and 2008. Kamphaeng Phet Province, in north-central Thailand had ... E. ROLLAND-HARRIS,etc.,al. Hospitalization of pregnant women with pandemic A(H1N1) 2009 influenza in Canada. Epidemiology and Infection. Abstract
submitted by kickingbird at Sep, 17, 2011 from Epidemiology and Infection (via http://journals.cambridge.org/action/displayAbstract?fromPag)
This article describes the epidemiology of pandemic A(H1N1) 2009 influenza in all Canadian pregnant women admitted to hospital, and compares it with historical inter-pandemic influenza activity. We used ... CHOU YY, Albrecht RA, Pica N, Lowen AC, et al.. The M segment of the 2009 new pandemic H1N1 influenza virus is critical for its high transmission efficiency in the guinea pig model. J Virol. 2011 Aug 31. Abstract
submitted by kickingbird at Sep, 7, 2011 from J Virol. 2011 Aug 31 (via http://www.ncbi.nlm.nih.gov/pubmed/21880744)
A remarkable feature of the 2009 pandemic H1N1 influenza virus is its efficient transmissibility in humans compared to precursor strains from the triple reassortant swine influenza virus lineage, which ... CHAN RW, Kang SS, Yen HL, Li AC, et al.. Tissue tropism of swine influenza viruses and reassortants in ex vivo cultures of the human respiratory tract and conjunctiva. J Virol. 2011 Aug 31. Abstract
submitted by kickingbird at Sep, 7, 2011 from J Virol. 2011 Aug 31 (via http://www.ncbi.nlm.nih.gov/pubmed/21880750)
The 2009 pandemic influenza H1N1 (H1N1pdm) virus was generated by reassortment of swine influenza viruses of different lineages. This was the first influenza pandemic to emerge in over four decades and ... OZAWA M, Victor ST, Taft AS, Yamada S, et al. Replication-incompetent influenza A viruses that stably express a foreign gene. J Gen Virol. 2011 Aug 31.. Abstract
submitted by kickingbird at Sep, 7, 2011 from J Gen Virol. 2011 Aug 31. (via http://www.ncbi.nlm.nih.gov/pubmed/21880840)
A biologically contained influenza A virus that stably expresses a foreign gene can be effectively traced, used to generate a novel multivalent vaccine, and have its replication easily assessed, all while ... Ohshima N, Iba Y, Kubota-Koketsu R, Asano Y, Okuno. Naturally occurring antibodies in a human can neutralize a broad spectrum of influenza strains including H3, H1, H2 and H5. J Virol. 2011 Aug 24.. Abstract
submitted by kickingbird at Aug, 29, 2011 from J Virol. 2011 Aug 24. (via http://www.ncbi.nlm.nih.gov/pubmed/21865387)
Influenza A viruses are classified into 16 subtypes according to serotypes of hemagglutinin (HA). It is generally thought that neutralizing antibodies (Abs) are not broadly cross-reactive among HA subtypes. ... Marcelin G, Aldridge JR, Duan S, Ghoneim HE, Rehg. Fatal outcome of pandemic H1N1 2009 influenza virus infection is associated with immunopathology and impaired lung repair, not enhanced viral burden in pregnant mice. J Virol. 2011 Aug 24.. Abstract
submitted by kickingbird at Aug, 29, 2011 from J Virol. 2011 Aug 24. (via http://www.ncbi.nlm.nih.gov/pubmed/21865394)
Pandemic A (H1N1) 2009 influenza virus (pH1N1) infection in pregnant women can be severe. The mechanisms that affect infection outcome in this population are not well understood. To address this, pregnant ... Khurana S, Wu J, Verma N, Verma S, Raghunandan R,. H5N1 virus-like particle vaccine elicits cross-reactive neutralizing antibodies in humans that preferentially bind to oligomeric form of influenza hemagglutinin. J Virol. 2011 Aug 24. Abstract
submitted by kickingbird at Aug, 29, 2011 from J Virol. 2011 Aug 24 (via http://www.ncbi.nlm.nih.gov/pubmed/21865396)
Transmission of pathogenic avian influenza viruses (AIV) from wild birds to domestic poultry and humans is continuing in multiple countries around the world. In preparation for a potential AIV pandemic, ... Li C, Bankhead A 3rd, Eisfeld AJ, Hatta Y, Jeng S,. Host Regulatory Network Response to Infection with Highly Pathogenic H5N1 Avian Influenza Virus. J Virol. 2011 Aug 24. Abstract
submitted by kickingbird at Aug, 29, 2011 from J Virol. 2011 Aug 24 (via http://www.ncbi.nlm.nih.gov/pubmed/21865398)
Over the last decade, more than half of humans infected with highly pathogenic avian influenza (HPAI) H5N1 viruses have died, and yet virus-induced host signaling has yet to be clearly elucidated. Airway ... Lee HK, Lee CK, Loh TP, Tang JW, Tambyah PA, Koay. A high-resolution melting approach to efficient identification and quantification of H275Y mutant influenza H1N1/2009 in mixed virus population samples. J Clin Microbiol. 2011 Aug 24.. Abstract
submitted by kickingbird at Aug, 29, 2011 from J Clin Microbiol. 2011 Aug 24. (via http://www.ncbi.nlm.nih.gov/pubmed/21865430)
The single nucleotide variant (SNV), 823C to T (His275Tyr), responsible for oseltamivir drug-resistance has been detected in some isolates of the influenza A/H1N1/2009 virus. Early detection of the presence ... Han, F., Lin, L., Warby, S. C., Faraco, J., Li, J.. Narcolepsy onset is seasonal and increased following the 2009 H1N1 pandemic in china. Annals of Neurology. doi: 10.1002/ana.22587. Abstract
submitted by kickingbird at Aug, 25, 2011 from Annals of Neurology. doi: 10.1002/ana.22587 (via http://onlinelibrary.wiley.com/doi/10.1002/ana.22587/abstrac)
Abstract
Objective:
Narcolepsy is caused by the loss of hypocretin/orexin neurons in the hypothalamus, which is likely the result of an autoimmune process. Recently, concern has been raised over ... Justin Lessler,etc.,al. Location-specific patterns of exposure to recent pre-pandemic strains of influenza A in southern China. Nature Communications 2, 423 doi:10.1038/ncomms143. Abstract
submitted by kickingbird at Aug, 12, 2011 from Nature Communications 2, 423 doi:10.1038/ncomms143 (via http://www.nature.com/ncomms/journal/v2/n8/full/ncomms1432.h)
Variation in influenza incidence between locations is commonly observed on large spatial scales. It is unclear whether such variation occurs on smaller spatial scales and whether it is the result of heterogeneities ... Hui-Ling Yen, Chi-Hui Liang, Chung-Yi Wu, Heather. Hemagglutinin–neuraminidase balance confers respiratory-droplet transmissibility of the pandemic H1N1 influenza virus in ferrets. pnas.1111000108. Abstract
submitted by kickingbird at Aug, 12, 2011 from pnas.1111000108 (via http://www.pnas.org/content/early/2011/08/05/1111000108.abst)
A novel reassortant derived from North American triple-reassortant (TRsw) and Eurasian swine (EAsw) influenza viruses acquired sustained human-to-human transmissibility and caused the 2009 influenza pandemic. ... Guan R, Ma LC, Leonard PG, Amer BR, Sridharan H, Z. Structural basis for the sequence-specific recognition of human ISG15 by the NS1 protein of influenza B virus.. Proc Natl Acad Sci U S A. 2011 Aug 1.. Abstract
submitted by kickingbird at Aug, 12, 2011 from Proc Natl Acad Sci U S A. 2011 Aug 1. (via http://www.ncbi.nlm.nih.gov/pubmed/21808041)
Interferon-induced ISG15 conjugation plays an important antiviral role against several viruses, including influenza viruses. The NS1 protein of influenza B virus (NS1B) specifically binds only human and ... Meroz D, Yoon SW, Ducatez MF, Fabrizio TP, Webby R. Putative amino acid determinants of the emergence of the 2009 influenza A (H1N1) virus in the human population. Proc Natl Acad Sci U S A. 2011 Aug 1.. Abstract
submitted by kickingbird at Aug, 12, 2011 from Proc Natl Acad Sci U S A. 2011 Aug 1. (via http://www.ncbi.nlm.nih.gov/pubmed/21808039)
The emergence of the unique H1N1 influenza A virus in 2009 resulted in a pandemic that has spread to over 200 countries. The constellation of molecular factors leading to the emergence of this strain is ... Lalle E, Bordi L, Meschi S, Selleri M, Valli MB, P. Comparison of two real-time RT-PCR-based systems for the detection and typing of the pandemic influenza A virus, 2009. J Virol Methods. 2011 Jul 21. Abstract
submitted by kickingbird at Aug, 12, 2011 from J Virol Methods. 2011 Jul 21 (via http://www.ncbi.nlm.nih.gov/pubmed/21807027)
During the 2009 pandemic the Virology Laboratory of L. Spallanzani, Rome, Italy, adopted a real-time RT-PCR developed by the Centers for Disease Control and Prevention (CDC), Atlanta, Georgia to diagnose ... Zhirnov OP, Klenk HD, Wright PF.. Aprotinin and similar protease inhibitors as drugs against influenza. Antiviral Res. 2011 Jul 23. Abstract
submitted by kickingbird at Aug, 12, 2011 from Antiviral Res. 2011 Jul 23 (via http://www.ncbi.nlm.nih.gov/pubmed/21802447)
Efforts to develop new antiviral chemotherapeutic approaches are focusing on compounds that target either influenza virus replication itself or host factor(s) that are critical to influenza replication. ... Fiebig L, Soyka J, Buda S, Buchholz U, Dehnert M,. Avian influenza A(H5N1) in humans: new insights from a line list of World Health Organization confirmed cases, September 2006 to August 2010. Eurosurveillance, Volume 16, Issue 32, 11 August 2. Abstract
submitted by kickingbird at Aug, 12, 2011 from Eurosurveillance, Volume 16, Issue 32, 11 August 2 (via http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=1)
Introduction
Avian influenza (AI) has received public attention since 1997 when human infections and thereof six fatal cases due to the highly pathogenic avian influenza A(H5N1) virus strain were ... Kimble JB, Sorrell E, Shao H, Martin PL, Perez DR.. Compatibility of H9N2 avian influenza surface genes and 2009 pandemic H1N1 internal genes for transmission in the ferret model. Proc Natl Acad Sci U S A. 2011 Jul 5. Abstract
submitted by kickingbird at Jul, 13, 2011 from Proc Natl Acad Sci U S A. 2011 Jul 5 (via http://www.ncbi.nlm.nih.gov/pubmed/21730147)
In 2009, a novel H1N1 influenza (pH1N1) virus caused the first influenza pandemic in 40 y. The virus was identified as a triple reassortant between avian, swine, and human influenza viruses, highlighting ... 7516 items, 20/Page, Page[283/376][|<<] [|<] [281] [282] [283] [284] [285] [286] [287] [288] [289] [290] [>|] [>>|] |
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