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2024-7-18 1:24:31
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Bertran K, Pérez-Ramírez E, Busquets N, Dolz R, Ra. Pathogenesis and transmissibility of highly (H7N1) and low (H7N9) pathogenic avian influenza virus infection in red-legged partridge (Alectoris rufa).. Vet Res. 2011 Feb 7;42(1):24. doi: 10.1186/1297-97.  Abstract  
submitted by kickingbird at Mar, 31, 2013 from Vet Res. 2011 Feb 7;42(1):24. doi: 10.1186/1297-97 (via http://www.ncbi.nlm.nih.gov/pubmed/21314907)
An experimental infection with highly pathogenic avian influenza virus (HPAIV) and low pathogenic avian influenza virus (LPAIV) was carried out in red-legged partridges (Alectoris rufa) in order to study ...

Pérez-Ramírez E, Gerrikagoitia X, Barral M, H?fle. Detection of low pathogenic avian influenza viruses in wild birds in Castilla-La Mancha (south central Spain).. Vet Microbiol. 2010 Dec 15;146(3-4):200-8. doi: 10.  Abstract  
submitted by kickingbird at Mar, 31, 2013 from Vet Microbiol. 2010 Dec 15;146(3-4):200-8. doi: 10 (via http://www.ncbi.nlm.nih.gov/pubmed/20605691)
The Iberian Peninsula is located along the East Atlantic and Black Sea/Mediterranean flyways and is the third ranking European country as wintering quarter for wild migrating birds after Turkey and Rumania. ...

HARRIS AK, Meyerson JR, Matsuoka Y, Kuybeda O, et. Structure and accessibility of HA trimers on intact 2009 H1N1 pandemic influenza virus to stem region-specific neutralizing antibodies. Proc Natl Acad Sci U S A. 2013 Mar 4.  Abstract  
submitted by kickingbird at Mar, 10, 2013 from Proc Natl Acad Sci U S A. 2013 Mar 4 (via http://www.ncbi.nlm.nih.gov/pubmed/23460696)
Rapid antigenic variation of HA, the major virion surface protein of influenza A virus, remains the principal challenge to the development of broader and more effective vaccines. Some regions of HA, such ...

SANTOS A, Pal S, Chacon J, Meraz K, et al. SUMOylation affects the interferon blocking activity of the influenza A non-structural protein NS1 without affecting its stability or cellular localization. J Virol. 2013 Mar 6.  Abstract  
submitted by kickingbird at Mar, 10, 2013 from J Virol. 2013 Mar 6 (via http://www.ncbi.nlm.nih.gov/pubmed/23468495)
Our pioneering studies on the interplay between the Small Ubiquitin-like MOdifier (SUMO) and influenza A virus identified the non-structural NS1 protein as the first known SUMO target of influenza virus ...

PETERSEN H, Wang Z, Lenz E, Pleschka S, et al. Reassortment of NS-segments modifies highly-pathogenic avian influenza virus interaction with avian hosts and host cells. J Virol. 2013 Mar 6.  Abstract  
submitted by kickingbird at Mar, 10, 2013 from J Virol. 2013 Mar 6 (via http://www.ncbi.nlm.nih.gov/pubmed/23468508)
Highly pathogenic avian influenza viruses (HPAIV) of subtypes H5 and H7 have caused numerous outbreaks in diverse poultry species and rising numbers of human infections. Both HPAIV subtypes support a growing ...

Fontana J, Steven AC.. At low pH, Influenza virus matrix protein M1 undergoes a conformational change prior to dissociating from the membrane. J Virol. 2013 Mar 6.  Abstract  
submitted by kickingbird at Mar, 10, 2013 from J Virol. 2013 Mar 6 (via http://www.ncbi.nlm.nih.gov/pubmed/23468509)
The M1 matrix protein of influenza A virus, which plays multiple roles in virion assembly and infection, underlies the viral envelope. However, previous studies have given differing accounts of the number ...

GOVORKOVA EA, Baranovich T, Seiler P, Armstrong J,. Antiviral resistance among highly pathogenic influenza A (H5N1) viruses isolated worldwide in 2002-2012 shows need for continued monitoring. Antiviral Res. 2013 Feb 28..  Abstract  
submitted by kickingbird at Mar, 10, 2013 from Antiviral Res. 2013 Feb 28. (via http://www.ncbi.nlm.nih.gov/pubmed/23458714)
Highly pathogenic (HP) H5N1 influenza viruses are evolving pathogens with the potential to cause sustained human-to-human transmission and pandemic virus spread. Specific antiviral drugs can play an important ...

Tamerius JD, Shaman J, Alonso WJ, et al.. Environmental Predictors of Seasonal Influenza Epidemics across Temperate and Tropical Climates. PLoS Pathog 9(3): e1003194. doi:10.1371/journal.pp.  Abstract  
submitted by kickingbird at Mar, 10, 2013 from PLoS Pathog 9(3): e1003194. doi:10.1371/journal.pp (via http://www.plospathogens.org/article/info:doi/10.1371/journa)
Abstract Human influenza infections exhibit a strong seasonal cycle in temperate regions. Recent laboratory and epidemiological evidence suggests that low specific humidity conditions facilitate the ...

Amesh A. Adalja. ECMO for Severe Influenza:Description of a Large French Cohort Study. Center for Biosecurity of UPMC.  Abstract  
submitted by kickingbird at Mar, 9, 2013 from Center for Biosecurity of UPMC (via http://www.upmc-biosecurity.org/)
When a young otherwise healthy individual develops severe acute respiratory distress syndrome (ARDS), rescue therapies are often employed to improve oxygenation, with extra-corporeal membrane oxygenation ...

M Morita, etc.,al. The Lipid Mediator Protectin D1 Inhibits Influenza Virus Replication and Improves Severe Influenza. Cell, 07 March 2013.  Abstract  
submitted by kickingbird at Mar, 8, 2013 from Cell, 07 March 2013 (via http://www.cell.com/retrieve/pii/S009286741300216X?cc=y)
Influenza A viruses are a major cause of mortality. Given the potential for future lethal pandemics, effective drugs are needed for the treatment of severe influenza such as that caused by H5N1 viruses. ...

L Pena, etc.,al. Influenza viruses with rearranged genomes as live-attenuated vaccines. J Virol, published online Feb 28.  Abstract  
submitted by kickingbird at Mar, 8, 2013 from J Virol, published online Feb 28 (via http://jvi.asm.org/content/early/2013/02/20/JVI.02490-12.sho)
H5N1 and H9N2 avian influenza subtypes top the World Health Organization's list for the greatest pandemic potential. Inactivated H5N1 vaccines induce limited immune responses and, in the case of live attenuated ...

Noti JD, Blachere FM, McMillen CM, Lindsley WG, Ka. High Humidity Leads to Loss of Infectious Influenza Virus from Simulated Coughs. PLoS ONE 8(2): e57485. doi:10.1371/journal.pone.00.  Abstract  
submitted by kickingbird at Mar, 8, 2013 from PLoS ONE 8(2): e57485. doi:10.1371/journal.pone.00 (via http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjourna)
Abstract Background The role of relative humidity in the aerosol transmission of influenza was examined in a simulated examination room containing coughing and breathing manikins. Methods Nebulized ...

ME Sundaram, etc.,al. Vitamin D is not associated with serologic response to influenza vaccine in adults over 50 years old. Vaccine, published online Feb 28.  Abstract  
submitted by kickingbird at Mar, 8, 2013 from Vaccine, published online Feb 28 (via http://www.sciencedirect.com/science/article/pii/S0264410X13)
Abstract Vitamin D deficiency has been implicated in risk of respiratory illness. We determined whether serum vitamin D levels are related to influenza vaccine response measured by hemagglutinin antibody ...

Dobrovolny HM, Reddy MB, Kamal MA, Rayner CR, Beau. Assessing Mathematical Models of Influenza Infections Using Features of the Immune Response. PLoS ONE 8(2): e57088. doi:10.1371/journal.pone.00.  Abstract  
submitted by kickingbird at Mar, 8, 2013 from PLoS ONE 8(2): e57088. doi:10.1371/journal.pone.00 (via http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjourna)
The role of the host immune response in determining the severity and duration of an influenza infection is still unclear. In order to identify severity factors and more accurately predict the course of ...

EJ Nicoli, etc.,al. Influenza and RSV make a modest contribution to invasive pneumococcal disease incidence in the UK. J Infect, published online Mar 5.  Abstract  
submitted by kickingbird at Mar, 8, 2013 from J Infect, published online Mar 5 (via http://www.sciencedirect.com/science/article/pii/S0163445313)
Summary Objectives The common seasonality of incidence of invasive pneumococcal disease (IPD) and viral respiratory infections has long been recognized, however, the extent to which this affects the ...

Wilson HM, Hall JS, Flint PL, Franson JC, Ely CR,. High Seroprevalence of Antibodies to Avian Influenza Viruses among Wild Waterfowl in Alaska: Implications for Surveillance. PLoS ONE 8(3): e58308. doi:10.1371/journal.pone.00.  Abstract  
submitted by kickingbird at Mar, 7, 2013 from PLoS ONE 8(3): e58308. doi:10.1371/journal.pone.00 (via http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjourna)
We examined seroprevalence (presence of detectable antibodies in serum) for avian influenza viruses (AIV) among 4,485 birds, from 11 species of wild waterfowl in Alaska (1998–2010), sampled during breeding/molting ...

Suzanne E. Ohmit,etc.,al. Influenza Vaccine Effectiveness in the Community and the Household. Clin Infect Dis. (2013).  Abstract  
submitted by kickingbird at Mar, 7, 2013 from Clin Infect Dis. (2013) (via http://cid.oxfordjournals.org/content/early/2013/02/14/cid.c)
Background.?There is a recognized need to determine influenza vaccine effectiveness on an annual basis and a long history of studying respiratory illnesses in households. Methods.?We recruited 328 households ...

YAMAMOTO N, Soda K, Sakoda Y, Okamatsu M, et al. Proteins of duck influenza virus responsible for acquisition of pathogenicity in chickens. Virus Res. 2013 Feb 19. pii: S0168-1702(13)00050-6.  Abstract  
submitted by kickingbird at Mar, 6, 2013 from Virus Res. 2013 Feb 19. pii: S0168-1702(13)00050-6 (via http://www.ncbi.nlm.nih.gov/pubmed/23434880)
Influenza virus rgVac1sub-P0 (H5N1) (rgVac1-P0), in which a pair of dibasic amino acid residues was introduced at the cleavage site of the HA of a reassortant of H5N2 and H7N1 viruses of duck origin, was ...

Zaraket H, Bridges OA, Russell CJ.. The pH of Activation of the Hemagglutinin Protein Regulates H5N1 Influenza Virus Replication and Pathogenesis in Mice. J Virol. 2013 Feb 28.  Abstract  
submitted by kickingbird at Mar, 6, 2013 from J Virol. 2013 Feb 28 (via http://www.ncbi.nlm.nih.gov/pubmed/23449784)
After receptor binding and internalization during influenza virus entry, the hemagglutinin (HA) protein is triggered by low pH to undergo irreversible conformational changes that mediate membrane fusion. ...

TSE LV, Marcano VC, Huang W, Pocwierz MS, et al. Plasmin-mediated activation of pandemic H1N1 influenza virus hemagglutinin independent of the viral neuraminidase. J Virol. 2013 Feb 28.  Abstract  
submitted by kickingbird at Mar, 6, 2013 from J Virol. 2013 Feb 28 (via http://www.ncbi.nlm.nih.gov/pubmed/23449787)
Influenza virus is well recognized to modulate host tropism and pathogenesis based on mutations in the proteolytic cleavage site of the viral hemagglutinin (HA), which activates HA and exposes the fusion ...

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