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2024-3-29 18:04:26
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ANCHISI S, Guerra J, Mottet-Osman G, Garcin D, et. Mismatches in Influenza A virus vRNA panhandle prevent RIG-I sensing by impairing RNA/RIG-I complex formation. J Virol. 2015 Oct 7. pii: JVI.01671-15..  Abstract  
submitted by kickingbird at Oct, 13, 2015 from J Virol. 2015 Oct 7. pii: JVI.01671-15. (via http://www.ncbi.nlm.nih.gov/pubmed/26446607)
Influenza virus RNA promoter panhandle structures are believed to be sensed by RIG-I. The occurrence of mismatches in this dsRNA structure raises questions about their effect on innate sensing. Our results ...

PICHYANGKUL S, Yongvanitchit K, Limsalakpetch A, K. Tissue Distribution of Memory T and B Cells in Rhesus Monkeys following Influenza A Infection. J Immunol. 2015 Sep 25..  Abstract  
submitted by kickingbird at Oct, 9, 2015 from J Immunol. 2015 Sep 25. (via http://www.ncbi.nlm.nih.gov/pubmed/26408671)
Studies of influenza-specific immune responses in humans have largely assessed systemic responses involving serum Ab and peripheral blood T cell responses. However, recent evidence indicates that tissue-resident ...

FERGUSON L, Eckard L, Epperson WB, Long LP, et al. Influenza D virus infection in Mississippi beef cattle. Virology. 2015 Sep 16;486:28-34. doi:.  Abstract  
submitted by kickingbird at Sep, 27, 2015 from Virology. 2015 Sep 16;486:28-34. doi: (via http://www.ncbi.nlm.nih.gov/pubmed/26386554)
A new member of the Orthomyxoviridae family, influenza D virus (IDV), was first reported in swine in the Midwest region of the United States. This study aims to extend our knowledge on the IDV epidemiology ...

FULTON BO, Palese P, Heaton NS. Replication competent influenza B reporter viruses as tools for screening antivirals and antibodies. J Virol. 2015 Sep 23..  Abstract  
submitted by kickingbird at Sep, 27, 2015 from J Virol. 2015 Sep 23. (via http://www.ncbi.nlm.nih.gov/pubmed/26401044)
Influenza B virus is a human pathogen responsible for significant health and economic burden. Research into this pathogen has been limited by the lack of reporter viruses. Here we describe the development ...

OKUYA K, Kawabata T, Nagano K, Tsukiyama-Kohara K,. Isolation and characterization of influenza A viruses from environmental water at an overwintering site of migratory birds in Japan. Arch Virol. 2015 Sep 21..  Abstract  
submitted by kickingbird at Sep, 27, 2015 from Arch Virol. 2015 Sep 21. (via http://www.ncbi.nlm.nih.gov/pubmed/26392284)
The Izumi plain in Kagoshima prefecture, Japan, is an overwintering site of more than 10,000 cranes. The wet paddy areas are artificially created to provide roosting sites for the cranes every winter. ...

VAN POUCKE S, Doedt J, Baumann J, Qiu Y, et al. Role of Substitutions in the Hemagglutinin in the Emergence of the 1968 Pandemic Influenza Virus. J Virol. 2015 Sep 16. pii: JVI.01292-15..  Abstract  
submitted by kickingbird at Sep, 21, 2015 from J Virol. 2015 Sep 16. pii: JVI.01292-15. (via http://www.ncbi.nlm.nih.gov/pubmed/26378170)
Hemagglutinin (HA) of H3N2/1968 pandemic influenza viruses differed from putative avian precursor by seven amino acid substitutions. Substitutions Q226L and G228S are known to be essential for avian-to-mammalian ...

TRAVANTY E, Zhou B, Zhang H, Di YP, et al. Differential susceptibility of human lung primary cells to H1N1 influenza viruses. J Virol. 2015 Sep 16..  Abstract  
submitted by kickingbird at Sep, 21, 2015 from J Virol. 2015 Sep 16. (via http://www.ncbi.nlm.nih.gov/pubmed/26378172)
Human alveolar epithelial cells (AECs) and alveolar macrophages (AMs) are the first lines of lung defense. In this study we report that AECs are the direct targets for H1N1 viruses that have circulated ...

TAYLOR G, Abdesselam K, Pelude L, Fernandes R, et. Epidemiological features of influenza in Canadian adult intensive care unit patients. Epidemiol Infect. 2015 Sep 18:1-10..  Abstract  
submitted by kickingbird at Sep, 21, 2015 from Epidemiol Infect. 2015 Sep 18:1-10. (via http://www.ncbi.nlm.nih.gov/pubmed/26384310)
To identify predictive factors and mortality of patients with influenza admitted to intensive care units (ICU) we carried out a prospective cohort study of patients hospitalized with laboratory-confirmed ...

LEI H, Peng X, Zhao D, Jiao H, et al. Cross-protection of Lactococcus lactis-displayed HA2 subunit against homologous and heterologous influenza A viruses in mice. Arch Virol. 2015 Sep 11.  Abstract  
submitted by kickingbird at Sep, 21, 2015 from Arch Virol. 2015 Sep 11 (via http://www.ncbi.nlm.nih.gov/pubmed/26358264)
Current influenza vaccines provide strain-specific protection against homologous subtypes and need to be updated annually. Therefore, it is essential to develop a universal vaccine that would induce broadly ...

WEISS R, Laengle J, Sachet M, Shurygina AP, et al. Interleukin-24 inhibits influenza A virus replication in vitro through induction of toll-like receptor 3 dependent apoptosis. Antiviral Res. 2015 Sep 11..  Abstract  
submitted by kickingbird at Sep, 21, 2015 from Antiviral Res. 2015 Sep 11. (via http://www.ncbi.nlm.nih.gov/pubmed/26367324)
New anti-viral agents and strategies are urgently needed to fight rapidly mutating viruses, as vaccine programs cannot react fast enough to prevent pandemics. Recently, we have shown that interleukin-24 ...

Yuan J, Lau EH, Li K, Leung YH, Yang Z, Xie C, et. Effect of live poultry market closure on avian influenza A(H7N9) virus activity in Guangzhou, China, 2014. Emerg Infect Dis. 2015 Oct.  Abstract  
submitted by kickingbird at Sep, 9, 2015 from Emerg Infect Dis. 2015 Oct (via http://wwwnc.cdc.gov/eid/article/21/10/15-0623_article)
We assessed the effect of closing live poultry markets in China on influenza A(H7N9) virus detection and viability. Intensive sampling was carried out before, during, and after a 2-week citywide market ...

LI Q, Wang X, Sun Z, Hu J, et al. Adaptive mutations in PB2 gene contribute to the high virulence of a natural reassortant H5N2 avian influenza virus in mice. Virus Res. 2015 Aug 24;210:255-263.  Abstract  
submitted by kickingbird at Sep, 7, 2015 from Virus Res. 2015 Aug 24;210:255-263 (via http://www.ncbi.nlm.nih.gov/pubmed/26315686)
The highly pathogenic A/chicken/Hebei/1102/2010 (HB10) H5N2 virus is a natural reassortant derived from circulating H5N1 and endemic H9N2 avian influenza viruses (AIV). To evaluate the potential of its ...

WILSON JR, Guo Z, Tzeng WP, Garten RJ, et al. Diverse antigenic site targeting of influenza hemagglutinin in the murine antibody recall response to A(H1N1)pdm09 virus. Virology. 2015 Aug 25;485:252-262. doi: 10.1016/j.  Abstract  
submitted by kickingbird at Sep, 7, 2015 from Virology. 2015 Aug 25;485:252-262. doi: 10.1016/j (via http://www.ncbi.nlm.nih.gov/pubmed/26318247)
Here we define the epitopes on HA that are targeted by a group of 9 recombinant monoclonal antibodies (rmAbs) isolated from memory B cells of mice, immunized by infection with A(H1N1)pdm09 virus followed ...

HOFFMANN J, Otte A, Thiele S, Lotter H, et al. Sex differences in H7N9 influenza A virus pathogenesis. Vaccine. 2015 Aug 25. pii: S0264-410X(15)01171-8.  Abstract  
submitted by kickingbird at Sep, 7, 2015 from Vaccine. 2015 Aug 25. pii: S0264-410X(15)01171-8 (via http://www.ncbi.nlm.nih.gov/pubmed/26319064)
Sex, gender and age have an impact on incidence and severity of several infectious diseases. Here, we analyzed reported human cases of avian H7N9 influenza A virus infections for potential sex-dependent ...

WIERSMA LC, Vogelzang-van Trierum SE, Kreijtz JH,. Heterosubtypic immunity to H7N9 influenza virus in isogenic guinea pigs after infection with pandemic H1N1 virus. Vaccine. 2015 Aug 25. pii: S0264-410X(15)01165-2.  Abstract  
submitted by kickingbird at Sep, 7, 2015 from Vaccine. 2015 Aug 25. pii: S0264-410X(15)01165-2 (via http://www.ncbi.nlm.nih.gov/pubmed/26319067)
Heterosubtypic immunity is defined as immune-mediated (partial) protection against an influenza virus induced by an influenza virus of another subtype to which the host has not previously been exposed. ...

BOIRON K, Sarazin M, Debin M, Raude J, et al. Opinion about seasonal influenza vaccination among the general population 3 years after the A(H1N1)pdm2009 influenza pandemic. Vaccine. 2015 Aug 28. pii: S0264-410X.  Abstract  
submitted by kickingbird at Sep, 7, 2015 from Vaccine. 2015 Aug 28. pii: S0264-410X (via http://www.ncbi.nlm.nih.gov/pubmed/26322844)
OBJECTIVE: To assess the opinions of the French general population about seasonal influenza vaccination three years after the A(H1N1)pdm 09 pandemic and identify factors associated with a neutral or ...

ZHAO D, Fukuyama S, Yamada S, Lopes TJ, et al. Molecular determinants of virulence and stability of a reporter-expressing H5N1 influenza A virus. J Virol. 2015 Sep 2. pii: JVI.01886-15..  Abstract  
submitted by kickingbird at Sep, 7, 2015 from J Virol. 2015 Sep 2. pii: JVI.01886-15. (via http://www.ncbi.nlm.nih.gov/pubmed/26339046)
We previously reported that an H5N1 virus carrying the Venus reporter gene, which was inserted into the NS gene segment from A/Puerto Rico/8/1934 (H1N1) virus (Venus-H5N1 virus), became more lethal to ...

VERHAGEN JH, Hofle U, van Amerongen G, van de Bild. Long-term effect of serial infections with H13 and H16 low pathogenic avian influenza viruses in black-headed gulls. J Virol. 2015 Sep 2. pii: JVI.01765-15..  Abstract  
submitted by kickingbird at Sep, 7, 2015 from J Virol. 2015 Sep 2. pii: JVI.01765-15. (via http://www.ncbi.nlm.nih.gov/pubmed/26339062)
Infections of domestic and wild birds with low pathogenic avian influenza viruses (LPAIV) have been associated with protective immunity to subsequent infection. However, the degree and duration of immunity ...

WIERSMA LC, Kreijtz JH, Vogelzang-van Trierum SE,. Virus replication kinetics and pathogenesis of infection with H7N9 influenza virus in isogenic guinea pigs upon intratracheal inoculation. Vaccine. 2015 Aug 22. pii: S0264-410X(15)01177-9..  Abstract  
submitted by kickingbird at Aug, 30, 2015 from Vaccine. 2015 Aug 22. pii: S0264-410X(15)01177-9. (via http://www.ncbi.nlm.nih.gov/pubmed/26307235)
Since 2013, avian influenza viruses of subtype H7N9 have been transmitted from poultry to humans in China and caused severe disease. Concerns persist over the pandemic potential of this virus and further ...

SU WC, Hsu SF, Lee YY, Jeng KS, et al. A Nucleolar Protein, Ribosomal RNA Processing 1 Homolog B (RRP1B), Enhances the Recruitment of Cellular mRNA in Influenza Virus Transcription. J Virol. 2015 Aug 26. pii: JVI.01487-15.  Abstract  
submitted by kickingbird at Aug, 30, 2015 from J Virol. 2015 Aug 26. pii: JVI.01487-15 (via http://www.ncbi.nlm.nih.gov/pubmed/26311876)
Influenza A virus (IAV) undergoes RNA transcription by a unique capped mRNA-dependent transcription, which is carried out by the viral RNA-dependent RNA polymerase (RdRp), consisting of the viral PA, PB1 ...

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