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2024-5-1 17:23:25
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Briggs K, Kapczynski DR. Comparative analysis of PB2 residue 627E/K/V in H5 subtypes of avian influenza viruses isolated from birds and mammals. Front Vet Sci. 2023 Sep 1;10:1250952.  Abstract  
submitted by kickingbird at Sep, 19, 2023 from Front Vet Sci. 2023 Sep 1;10:1250952 (via https://www.frontiersin.org/articles/10.3389/fvets.2023.1250)
Avian influenza viruses (AIVs) are naturally found in wild birds, primarily in migratory waterfowl. Although species barriers exist, many AIVs have demonstrated the ability to jump from bird species to ...

Gao R, Pascua PNQ, Nguyen HT, Chesnokov A, Champio. New insights into the neuraminidase-mediated hemagglutination activity of influenza A(H3N2) viruses. Antiviral Res. 2023 Sep 15:105719.  Abstract  
submitted by kickingbird at Sep, 19, 2023 from Antiviral Res. 2023 Sep 15:105719 (via https://www.sciencedirect.com/science/article/pii/S016635422)
Influenza virus neuraminidase (NA) can act as a receptor-binding protein, a role commonly attributed to hemagglutinin (HA). In influenza A(H3N2) viruses, three NA amino acid residues have previously been ...

Jung Kj?r L, Ward MP, Boklund AE, Larsen LE, Hjuls. Using surveillance data for early warning modelling of highly pathogenic avian influenza in Europe reveals a seasonal shift in transmission, 2016-2022. Sci Rep. 2023 Sep 16;13(1):15396.  Abstract  
submitted by kickingbird at Sep, 18, 2023 from Sci Rep. 2023 Sep 16;13(1):15396 (via https://www.nature.com/articles/s41598-023-42660-7)
Avian influenza in wild birds and poultry flocks constitutes a problem for animal welfare, food security and public health. In recent years there have been increasing numbers of outbreaks in Europe, with ...

Patyk KA, Fields VL, Beam AL, Branan MA, McGuigan. Investigation of risk factors for introduction of highly pathogenic avian influenza H5N1 infection among commercial turkey operations in the United States, 2022: a case-control study. Front Vet Sci. 2023 Aug 30;10:1229071.  Abstract  
submitted by kickingbird at Sep, 17, 2023 from Front Vet Sci. 2023 Aug 30;10:1229071 (via https://www.frontiersin.org/articles/10.3389/fvets.2023.1229)
Introduction: The 2022-2023 highly pathogenic avian influenza (HPAI) H5N1 outbreak in the United States (U.S.) is the largest and most costly animal health event in U.S. history. Approximately 70% of commercial ...

Zhu W, Gu L. Clinical, epidemiological, and genomic characteristics of a seasonal influenza A virus outbreak in Beijing: A descriptive study. J Med Virol. 2023 Sep;95(9):e29106.  Abstract  
submitted by kickingbird at Sep, 17, 2023 from J Med Virol. 2023 Sep;95(9):e29106 (via https://onlinelibrary.wiley.com/doi/10.1002/jmv.29106)
China experienced a severe influenza season that began at the end of February 2023. The aim of this post hoc analysis was to investigate the clinical, epidemiological, and genomic features of this outbreak ...

Hewawaduge C, Kwon J, Sivasankar C, Park JY, Senev. Salmonella delivers H9N2 influenza virus antigens via a prokaryotic and eukaryotic dual-expression vector and elicits bivalent protection against avian influenza and fowl typhoid. Dev Comp Immunol. 2023 Sep 13:105058.  Abstract  
submitted by kickingbird at Sep, 17, 2023 from Dev Comp Immunol. 2023 Sep 13:105058 (via https://www.sciencedirect.com/science/article/abs/pii/S01453)
The H9N2 avian influenza virus significantly affects the health of poultry and humans. We identified a prokaryotic and eukaryotic dual-expression vector system, pJHL270, that can provide simultaneous MHC ...

Yu J, Sreenivasan C, Sheng Z, Zhai SL, Wollman JW,. A recombinant chimeric influenza virus vaccine expressing the consensus H3 hemagglutinin elicits broad hemagglutination inhibition antibodies against divergent swine H3N2 influenza viruses. Vaccine. 2023 Sep 7:S0264-410X(23)01060-5.  Abstract  
submitted by kickingbird at Sep, 12, 2023 from Vaccine. 2023 Sep 7:S0264-410X(23)01060-5 (via https://pubmed.ncbi.nlm.nih.gov/37689544/)
The global distribution and ongoing evolution of type A swine influenza virus (IAV-S) continue to pose significant challenges against developing broadly protective vaccines to control swine influenza. ...

Chen YQ, Su GM, Zhang JH, Li B, Ma KX, Zhang X, Hu. HVT-vectored H7 vaccine protects chickens from lethal infection with the highly pathogenic H7N9 Avian influenza virus. Vet Microbiol. 2023 Aug 20;285:109852.  Abstract  
submitted by kickingbird at Sep, 10, 2023 from Vet Microbiol. 2023 Aug 20;285:109852 (via https://www.sciencedirect.com/science/article/abs/pii/S03781)
Since mid-2016, the highly pathogenic H7N9 subtype avian influenza virus (AIV) has threatened both public health and the poultry industry. Although a vaccination strategy has been deemed imperative to ...

Brian R Wasik, Evin Rothschild, etc.,al. Understanding the divergent evolution and epidemiology of H3N8 influenza viruses in dogs and horses. Virus Evolution, Volume 9, Issue 2, 2023.  Abstract  
submitted by kickingbird at Sep, 10, 2023 from Virus Evolution, Volume 9, Issue 2, 2023 (via https://academic.oup.com/ve/article/9/2/vead052/7262942)
Cross-species virus transmission events can lead to dire public health emergencies in the form of epidemics and pandemics. One example in animals is the emergence of the H3N8 equine influenza virus (EIV), ...

Xiong F, Zhang C, Shang B, Zheng M, Wang Q, Ding Y. An mRNA-based broad-spectrum vaccine candidate confers cross-protection against heterosubtypic influenza A viruses. Emerg Microbes Infect. 2023 Sep 6:2256422.  Abstract  
submitted by kickingbird at Sep, 10, 2023 from Emerg Microbes Infect. 2023 Sep 6:2256422 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2023.2)
Influenza virus is a prominent cause of respiratory illness in humans. Current influenza vaccines offer strain-specific immunity, while provide limited protection against drifted strains. Broad-spectrum ...

Leguia M, Garcia-Glaessner A, Mu?oz-Saavedra B, Ju. Highly pathogenic avian influenza A (H5N1) in marine mammals and seabirds in Peru. Nat Commun. 2023 Sep 7;14(1):5489.  Abstract  
submitted by kickingbird at Sep, 10, 2023 from Nat Commun. 2023 Sep 7;14(1):5489 (via https://www.nature.com/articles/s41467-023-41182-0)
Highly pathogenic avian influenza (HPAI) A/H5N1 viruses (lineage 2.3.4.4b) are rapidly invading the Americas, threatening wildlife, poultry, and potentially evolving into the next global pandemic. In November ...

Liu X, Zhao T, Wang L, Yang Z, Luo C, Li M, Luo H,. A mosaic influenza virus-like particles vaccine provides broad humoral and cellular immune responses against influenza A viruses. NPJ Vaccines. 2023 Sep 7;8(1):132..  Abstract  
submitted by kickingbird at Sep, 10, 2023 from NPJ Vaccines. 2023 Sep 7;8(1):132. (via https://www.nature.com/articles/s41541-023-00728-5)
The development of a universal influenza vaccine to elicit broad immune responses is essential in reducing disease burden and pandemic impact. In this study, the mosaic vaccine design strategy and genetic ...

Le Y, Zhang J, Gong Z, Zhang Z, Nian X, Li X, Yu D. TRAF3 deficiency in MDCK cells improved sensitivity to the influenza A virus. Heliyon. 2023 Aug 21;9(9):e19246.  Abstract  
submitted by kickingbird at Sep, 10, 2023 from Heliyon. 2023 Aug 21;9(9):e19246 (via https://www.cell.com/heliyon/fulltext/S2405-8440(23)06454-X)
Tumor necrosis factor receptor-associated factor 3 (TRAF3), an adaptor protein, has significant and varying effects on immunity depending on cell types. The role of TRAF3 in Madin-Darby Canine Kidney Epithelial ...

Mirolo M, Pohlmann A, Ahrens AK, Kühl B, Rubio-Gar. Highly pathogenic avian influenza A virus (HPAIV) H5N1 infection in two European grey seals ( Halichoerus grypus) with encephalitis. Emerg Microbes Infect. 2023 Sep 8:2257810.  Abstract  
submitted by kickingbird at Sep, 10, 2023 from Emerg Microbes Infect. 2023 Sep 8:2257810 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2023.2)
Recent reports documenting sporadic infections in carnivorous mammals worldwide with highly pathogenic avian influenza virus (HPAIV) H5N1 clade 2.3.4.4b have raised concerns about the potential risk of ...

Bauer L, Benavides FFW, Veldhuis Kroeze EJB, de Wi. The neuropathogenesis of highly pathogenic avian influenza H5Nx viruses in mammalian species including humans. Trends Neurosci. 2023 Sep 6:S0166-2236(23)00190-X.  Abstract  
submitted by kickingbird at Sep, 10, 2023 from Trends Neurosci. 2023 Sep 6:S0166-2236(23)00190-X (via https://www.cell.com/trends/neurosciences/fulltext/S0166-223)
Circulation of highly pathogenic avian influenza (HPAI) H5Nx viruses of the A/Goose/Guangdong/1/96 lineage in birds regularly causes infections of mammals, including humans. In many mammalian species, ...

Lee HJ, Ryu G, Lee KI. Symptomatic Differences between Influenza A/H3N2 and A/H1N1 in Korea. J Clin Med. 2023 Aug 30;12(17):5651.  Abstract  
submitted by kickingbird at Sep, 10, 2023 from J Clin Med. 2023 Aug 30;12(17):5651 (via https://www.mdpi.com/2077-0383/12/17/5651)
Limited understanding exists regarding clinical distinctions between influenza A/H3N2 and A/H1N1 subtypes, particularly in primary health care. We conducted a comparative analysis of symptomatic characteristics ...

Honglei Sun, et.,al. Airborne transmission of human-isolated avian H3N8 influenza virus between ferrets. Cell. 2023 Sep 4.  Abstract  
submitted by kickingbird at Sep, 5, 2023 from Cell. 2023 Sep 4 (via https://www.cell.com/cell/fulltext/S0092-8674(23)00891-7)
H3N8 avian influenza viruses (AIVs) in China caused two confirmed human infections in 2022, followed by a fatal case reported in 2023. H3N8 viruses are widespread in chicken flocks; however, the zoonotic ...

Hassan DMZ, Sturm-Ramirez DK, Islam DMS, Afreen DS. Interpretation of molecular detection of avian influenza A virus in respiratory specimens collected from live bird market workers in Dhaka, Bangladesh: Infection or contamination?. Int J Infect Dis. 2023 Aug 29:S1201-9712(23)00706-.  Abstract  
submitted by kickingbird at Sep, 4, 2023 from Int J Infect Dis. 2023 Aug 29:S1201-9712(23)00706- (via https://www.ijidonline.com/article/S1201-9712(23)00706-3/ful)
Background: Interpreting rRT-PCR results for human avian influenza A virus (AIV) detection in contaminated settings like live bird markets (LBMs) without serology or viral culture poses a challenge.Methods: ...

Moreno A, Bonfante F, Bortolami A, Cassaniti I, Ca. Asymptomatic infection with clade 2.3.4.4b highly pathogenic avian influenza A(H5N1) in carnivore pets, Italy, April 2023. Euro Surveill. 2023 Aug;28(35).  Abstract  
submitted by kickingbird at Sep, 1, 2023 from Euro Surveill. 2023 Aug;28(35) (via https://pubmed.ncbi.nlm.nih.gov/37650905/)
In April 2023, an outbreak of clade 2.3.4.4b highly pathogenic avian influenza A(H5N1) viruses carrying the T271A mammalian adaptive mutation in the PB2 protein was detected in a backyard poultry farm ...

Kutter JS, Linster M, de Meulder D, Bestebroer TM,. Continued adaptation of A/H2N2 viruses during pandemic circulation in humans. J Gen Virol. 2023 Aug;104(8).  Abstract  
submitted by kickingbird at Sep, 1, 2023 from J Gen Virol. 2023 Aug;104(8) (via https://www.microbiologyresearch.org/content/journal/jgv/10.)
Influenza A viruses of the H2N2 subtype sparked a pandemic in 1957 and circulated in humans until 1968. Because A/H2N2 viruses still circulate in wild birds worldwide and human population immunity is low, ...

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