Reimering S, McHardy AC. Software for Characterizing the Antigenic and Genetic Evolution of Human Influenza Viruses. Methods Mol Biol. 2018;1836:551-565. Abstract
submitted by kickingbird at Aug, 31, 2018 from Methods Mol Biol. 2018;1836:551-565 (via https://www.ncbi.nlm.nih.gov/pubmed/30151591)
Influenza viruses are rapidly evolving pathogens causing annual epidemics and occasional pandemics. The accumulation of amino acid substitutions allows the virus to adapt to changing environments like ... Finn A. Clinical Trials of Influenza Vaccines: Special Challenges. Methods Mol Biol. 2018;1836:567-573. Abstract
submitted by kickingbird at Aug, 31, 2018 from Methods Mol Biol. 2018;1836:567-573 (via https://www.ncbi.nlm.nih.gov/pubmed/30151592)
Clinical trials of vaccines differ from those of drugs both practically and ethically. Influenza vaccine trials pose additional challenges which flow from the seasonality of the disease and vaccine programmes ... Imperiale MJ, Howard D, Casadevall A. The Silver Lining in Gain-of-Function Experiments with Pathogens of Pandemic Potential. Methods Mol Biol. 2018;1836:575-587.. Abstract
submitted by kickingbird at Aug, 31, 2018 from Methods Mol Biol. 2018;1836:575-587. (via https://www.ncbi.nlm.nih.gov/pubmed/30151593)
Half a decade after the contentious "gain-of-function" (GOF) debate of 2012 that followed experimentation showing that highly pathogenic avian influenza virus could become mammalian transmissible, it is ... Lipsitch M. Why Do Exceptionally Dangerous Gain-of-Function Experiments in Influenza?. Methods Mol Biol. 2018;1836:589-608. Abstract
submitted by kickingbird at Aug, 31, 2018 from Methods Mol Biol. 2018;1836:589-608 (via https://www.ncbi.nlm.nih.gov/pubmed/30151594)
This chapter makes the case against performing exceptionally dangerous gain-of-function experiments that are designed to create potentially pandemic and novel strains of influenza, for example, by enhancing ... Yu J, etc.,al. Influenza-Associated Hospitalization in Children Younger Than Five Years of Age in Suzhou, China, 2011- 2016. Pediatr Infect Dis J. 2018 Aug 27.. Abstract
submitted by kickingbird at Aug, 31, 2018 from Pediatr Infect Dis J. 2018 Aug 27. (via https://www.ncbi.nlm.nih.gov/pubmed/30153228)
BACKGROUND: Studying the burden and risk factors associated with severe illness from influenza infection in young children in eastern China will contribute to future cost-effectiveness analyses of local ... Tian T, etc.,al. H3N2 influenza virus infection enhances Oncostatin M expression in human nasal epithelium. Exp Cell Res. 2018 Aug 21. Abstract
submitted by kickingbird at Aug, 31, 2018 from Exp Cell Res. 2018 Aug 21 (via https://www.ncbi.nlm.nih.gov/pubmed/30142324)
Tight junctions (TJs) alteration is commonly seen in airway inflammatory diseases. Oncostatin M (OSM) is an inflammatory mediator associated with chronic rhinosinusitis with nasal polyps (CRSwNP). We have ... Belser JA, Maines TR, Tumpey TM. Importance of 1918 virus reconstruction to current assessments of pandemic risk. Virology. 2018 Aug 21;524:45-55. Abstract
submitted by kickingbird at Aug, 31, 2018 from Virology. 2018 Aug 21;524:45-55 (via https://www.ncbi.nlm.nih.gov/pubmed/30142572)
Reconstruction of the 1918 influenza virus has facilitated considerable advancements in our understanding of this extraordinary pandemic virus. However, the benefits of virus reconstruction are not limited ... D´Agostino I, etc.,al. Synthesis and biological evaluation of a library of hybrid derivatives as inhibitors of influenza virus PA-PB1 interaction. Eur J Med Chem. 2018 Aug 13;157:743-758. Abstract
submitted by kickingbird at Aug, 31, 2018 from Eur J Med Chem. 2018 Aug 13;157:743-758 (via https://www.ncbi.nlm.nih.gov/pubmed/30142611)
The limited treatment options against influenza virus along with the growing public health concerns regarding the continuous emergence of drug-resistant viruses make essential the development of new anti-flu ... Kronstad LM, Seiler C, Vergara R, Holmes SP. Differential Induction of IFN-α and Modulation of CD112 and CD54 Expression Govern the Magnitude of NK Cell IFN-γ Response to Influenza A Viruses. J Immunol. 2018 Aug 24. pii: ji1800161.. Abstract
submitted by kickingbird at Aug, 31, 2018 from J Immunol. 2018 Aug 24. pii: ji1800161. (via https://www.ncbi.nlm.nih.gov/pubmed/30143589)
In human and murine studies, IFN-γ is a critical mediator immunity to influenza. IFN-γ production is critical for viral clearance and the development of adaptive immune responses, yet excessive production ... Coletti P, Poletto C, Turbelin C, Blanchon T. Shifting patterns of seasonal influenza epidemics. Sci Rep. 2018 Aug 24;8(1):12786. Abstract
submitted by kickingbird at Aug, 31, 2018 from Sci Rep. 2018 Aug 24;8(1):12786 (via https://www.ncbi.nlm.nih.gov/pubmed/30143689)
Seasonal waves of influenza display a complex spatiotemporal pattern resulting from the interplay of biological, sociodemographic, and environmental factors. At country level many studies characterized ... Ermolenko EI, etc.,al. Anti-Influenza Activity of Enterocin B In vitro and Protective Effect of Bacteriocinogenic Enterococcal Probiotic Strain on Influenza Infection in Mouse Model. Probiotics Antimicrob Proteins. 2018 Aug 24.. Abstract
submitted by kickingbird at Aug, 31, 2018 from Probiotics Antimicrob Proteins. 2018 Aug 24. (via https://www.ncbi.nlm.nih.gov/pubmed/30143997)
In spite of scientific evidence demonstrating the antiviral activity of lactic-acids bacteria, little is known about the mechanism of their action. Previously, several bacteriocins isolated from lactic ... Newall AT, Chen C, Wood JG, Stockwell MS. Within-season influenza vaccine waning suggests potential net benefits to delayed vaccination in older adults in the United States. Vaccine. 2018 Aug 23. pii: S0264-410X(18)31114-9. Abstract
submitted by kickingbird at Aug, 31, 2018 from Vaccine. 2018 Aug 23. pii: S0264-410X(18)31114-9 (via https://www.ncbi.nlm.nih.gov/pubmed/30146403)
BACKGROUND: There is growing evidence that there is within (intra-) season waning of influenza vaccine protection in older adults, suggesting there may be a benefit to giving influenza vaccine closer to ... Ismail ZM, El-Deeb AH, El-Safty MM, Hussein HA. Enhanced pathogenicity of low-pathogenic H9N2 avian influenza virus after vaccination with infectious bronchitis live attenuated vaccine. Vet World. 2018 Jul;11(7):977-985. Abstract
submitted by kickingbird at Aug, 31, 2018 from Vet World. 2018 Jul;11(7):977-985 (via https://www.ncbi.nlm.nih.gov/pubmed/30147269)
Aim: In the present study, two experiments were carried out for studying the pathogenicity of H9N2 avian influenza virus (AIV) in broiler chickens after vaccination with different live respiratory viral ... Veerapandian R, Snyder JD, Samarasinghe AE. Influenza in Asthmatics: For Better or for Worse?. Front Immunol. 2018 Aug 10;9:1843. Abstract
submitted by kickingbird at Aug, 31, 2018 from Front Immunol. 2018 Aug 10;9:1843 (via https://www.ncbi.nlm.nih.gov/pubmed/30147697)
Asthma and influenza are two pathologic conditions of the respiratory tract that affect millions worldwide. Influenza virus of the 2009 pandemic was highly transmissible and caused severe respiratory disease ... Chan YD, Wong ML, Au KW, Chuang SK. Seasonal influenza vaccine effectiveness at primary care level, Hong Kong SAR, 2017/2018 winter. Hum Vaccin Immunother. 2018 Aug 27. Abstract
submitted by kickingbird at Aug, 31, 2018 from Hum Vaccin Immunother. 2018 Aug 27 (via https://www.ncbi.nlm.nih.gov/pubmed/30148689)
The 2017/18 winter influenza season in Hong Kong SAR started in early January 2018, predominated by influenza B/Yamagata. We collaborated with private medical practitioners of our sentinel surveillance ... Zheng D, Gao F, Zhao C, Ding Y, Cao Y. Comparative effectiveness of H7N9 vaccines in healthy individuals. Hum Vaccin Immunother. 2018 Aug 27.. Abstract
submitted by kickingbird at Aug, 31, 2018 from Hum Vaccin Immunother. 2018 Aug 27. (via https://www.ncbi.nlm.nih.gov/pubmed/30148691)
BACKGROUND: Avian H7N9 influenza viruses possess a potential pandemic threat to public health worldwide, and have caused severe infection and high mortality in humans. A series of clinical trials of H7N9 ... Parra-Rojas C, etc.,al. Neuraminidase Inhibitors in Influenza Treatment and Prevention?Is It Time to Call It a Day?. Viruses. 2018 Aug 25;10(9).. Abstract
submitted by kickingbird at Aug, 31, 2018 from Viruses. 2018 Aug 25;10(9). (via https://www.ncbi.nlm.nih.gov/pubmed/30149615)
Stockpiling neuraminidase inhibitors (NAIs) such as oseltamivir and zanamivir is part of a global effort to be prepared for an influenza pandemic. However, the contribution of NAIs for the treatment and ... Benkaroun J, Robertson GJ, Whitney H, Lang AS. Analysis of the Variability in the Non-Coding Regions of Influenza A Viruses. Vet Sci. 2018 Aug 25;5(3).. Abstract
submitted by kickingbird at Aug, 31, 2018 from Vet Sci. 2018 Aug 25;5(3). (via https://www.ncbi.nlm.nih.gov/pubmed/30149635)
The genomes of influenza A viruses (IAVs) comprise eight negative-sense single-stranded RNA segments. In addition to the protein-coding region, each segment possesses 5' and 3' non-coding regions (NCR) ... Grohskopf LA, Sokolow LZ, Broder KR, Walter E. Prevention and Control of Seasonal Influenza with Vaccines: Recommendations of the Advisory Committee on Immunization Practices-United States, 2018-19 Influenza Season. MMWR Recomm Rep. 2018 Aug 24;67(3):1-20. Abstract
submitted by kickingbird at Aug, 31, 2018 from MMWR Recomm Rep. 2018 Aug 24;67(3):1-20 (via https://www.ncbi.nlm.nih.gov/pubmed/30141464)
This report updates the 2017-18 recommendations of the Advisory Committee on Immunization Practices (ACIP) regarding the use of seasonal influenza vaccines in the United States (MMWR Recomm Rep 2017;66[No. ... Ni Y, Guo J, Turner D, Tizard I. An Improved Inactivated Influenza Vaccine with Enhanced Cross Protection. Front Immunol. 2018 Aug 9;9:1815.. Abstract
submitted by kickingbird at Aug, 31, 2018 from Front Immunol. 2018 Aug 9;9:1815. (via https://www.ncbi.nlm.nih.gov/pubmed/30140267)
Current inactivated influenza vaccines are strain-specific and poorly effective against variant or mismatched viruses. They are standardized based on their hemagglutinin (HA) or ability to induce strain-specific ... 8181 items, 20/Page, Page[230/410][|<<] [|<] [221] [222] [223] [224] [225] [226] [227] [228] [229] [230] [>|] [>>|] |
Related Pages:
Browse by Category
Learn about the flu news, articles, events and more
Subscribe to the weekly F.I.C newsletter!
|
- 
