Sun H, Yao W, Wang K, Qian Y, et al.. Inhibition of neddylation pathway represses influenza virus replication and pro-inflammatory responses. Virology 2017;514:230-239. Abstract
submitted by kickingbird at Dec, 31, 2017 from Virology 2017;514:230-239 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29248752/)
The neddylation pathway belongs post-translational modifications and plays important roles in regulating viral infection and replication. To address the relationship of influenza A virus with the neddylation ... Florek NW, Campos LM, Braun KM, McLean HQ, et al. An updated influenza A(H3N2) vaccine generates limited antibody responses to previously encountered antigens in children. Vaccine 2017 Dec 14. Abstract
submitted by kickingbird at Dec, 31, 2017 from Vaccine 2017 Dec 14 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29249543/)
BACKGROUND: Influenza vaccination may provide a "back-boost" to antibodies against previously encountered strains. If the back-boost effect is common, this could allow more aggressive vaccine updates, ... Raymond DD, Bajic G, Ferdman J, Suphaphiphat P, et. Conserved epitope on influenza-virus hemagglutinin head defined by a vaccine-induced antibody. Proc Natl Acad Sci U S A 2017 Dec 18. Abstract
submitted by kickingbird at Dec, 31, 2017 from Proc Natl Acad Sci U S A 2017 Dec 18 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29255041/)
Circulating influenza viruses evade neutralization in their human hosts by acquiring escape mutations at epitopes of prevalent antibodies. A goal for next-generation influenza vaccines is to reduce escape ... Iuliano AD, Roguski KM, Chang HH, Muscatello DJ, e. Estimates of global seasonal influenza-associated respiratory mortality: a modelling study. Lancet 2017 Dec 13. Abstract
submitted by kickingbird at Dec, 31, 2017 from Lancet 2017 Dec 13 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29248255/)
BACKGROUND: Estimates of influenza-associated mortality are important for national and international decision making on public health priorities. Previous estimates of 250?000-500?000 annual influenza ... Williams JA, Gui L, Hom N, Mileant A, et al. Dissection of epitope-specific mechanisms of neutralization of influenza virus by intact IgG and Fab fragments. J Virol 2017 Dec 20. Abstract
submitted by kickingbird at Dec, 31, 2017 from J Virol 2017 Dec 20 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29263254/)
The neutralizing antibody (nAb) response against the influenza virus's hemagglutinin (HA) fusion glycoprotein is important for preventing viral infection, but we lack a comprehensive understanding of the ... Zhang J, Lao G, Zhang R, Wei Z, et al. Genetic diversity and dissemination pathways of highly pathogenic H5N6 avian influenza viruses from birds in Southwestern China along the East Asian–Australian migration flyway. J Infect 2017 Dec 12. Abstract
submitted by kickingbird at Dec, 31, 2017 from J Infect 2017 Dec 12 (via http://www.journalofinfection.com/article/S0163-4453(17)3038)
Gao and her colleagues recently reported in this journal the increasing genetic diversity of novel H5N6 avian influenza viruses (AIVs) persisting in Guangdong Province of China, which posed the serious ... Hornick EE, Banoth B, Miller AM, Zacharias ZR, et. Nlrp12 Mediates Adverse Neutrophil Recruitment during Influenza Virus Infection. J Immunol 2017 Dec 27. Abstract
submitted by kickingbird at Dec, 31, 2017 from J Immunol 2017 Dec 27 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29282312/)
Exaggerated inflammatory responses during influenza A virus (IAV) infection are typically associated with severe disease. Neutrophils are among the immune cells that can drive this excessive and detrimental ... Bhoye D, Cherian SS. Computational analysis of the effect of polymerase acidic (PA) gene mutation F35L in the 2009 pandemic influenza A (H1N1) virus on binding aspects of mononucleotides in the endonuclease domain. Arch Virol 2017 Dec 22. Abstract
submitted by kickingbird at Dec, 31, 2017 from Arch Virol 2017 Dec 22 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29273880/)
An F35L mutation in the N-terminal domain of the polymerase acidic protein (PA-Nter), which contains the active site of the endonuclease, has been reported to result in higher polymerase activity in mouse-adapted ... Yang JR, Cheng CY, Chen CY, Lin CH, et al. A virus-like particle vaccination strategy expands its tolerance to H3N2 antigenic drift by enhancing neutralizing antibodies against hemagglutinin stalk. Antiviral Res 2017;140:62-75. Abstract
submitted by kickingbird at Dec, 31, 2017 from Antiviral Res 2017;140:62-75 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28093338/)
Seasonal influenza viruses impact public health annually due to their continual evolution. However, the current inactivated seasonal vaccines provide poor protection against antigenically drifted viruses ... Li-Juan Zhang, Li Xia, Shu-Lin Liu, En-Ze Sun, Qiu. A “Driver Switchover” Mechanism of Influenza Virus Transport from Microfilaments to Microtubules. ACS Nano Publication Date (Web): December 12, 2017. Abstract
submitted by kickingbird at Dec, 25, 2017 from ACS Nano Publication Date (Web): December 12, 2017 (via http://pubs.acs.org/doi/10.1021/acsnano.7b06926)
When infecting host cells, influenza virus must move on microfilaments (MFs) at the cell periphery and then move along microtubules (MTs) through the cytosol to reach the perinuclear region for genome ... Chen L, Wang C, Luo J, Su W, Li M, Zhao N, Lyu W,. Histone Deacetylase 1 Plays an Acetylation-Independent Role in Influenza A Virus Replication. Front. Immunol., 12 December 2017. Abstract
submitted by kickingbird at Dec, 24, 2017 from Front. Immunol., 12 December 2017 (via https://www.frontiersin.org/articles/10.3389/fimmu.2017.0175)
Influenza A viruses (IAVs) take advantage of the host acetylation system for their own benefit. Whether the nucleoprotein (NP) of IAVs undergoes acetylation and the interaction between the NP and the class ... Belser JA, Brock N, Sun X, Jones J, Zanders N, Hod. Mammalian Pathogenesis and Transmission of Avian Influenza A(H7N9) Viruses, Tennessee, USA, 2017. Emerg Infect Dis. 2018 Jan;24(1):149-152. Abstract
submitted by kickingbird at Dec, 24, 2017 from Emerg Infect Dis. 2018 Jan;24(1):149-152 (via https://wwwnc.cdc.gov/eid/article/24/1/17-1574_article)
Infections with low pathogenicity and highly pathogenic avian influenza A(H7N9) viruses affected poultry in 4 states in the southeastern United States in 2017. We evaluated pathogenicity and transmission ... Tsou TP, Su CP, Huang WT, Yang JR, Liu MT.. Influenza A(H3N2) virus variants and patient characteristics during a summer influenza epidemic in Taiwan, 2017. Euro Surveill. 2017 Dec;22. Abstract
submitted by kickingbird at Dec, 24, 2017 from Euro Surveill. 2017 Dec;22 (via http://www.eurosurveillance.org/content/10.2807/1560-7917.ES)
Recently, influenza A(H3N2) virus variants carrying substitutions N121K, S144K and T135K have been reported in Canada, Denmark, Israel and the United Kingdom (UK), causing outbreaks during the northern ... Y Yan, Y Du, G Wang, K Li. Non-structural protein 1 of H3N2 influenza A virus induces nucleolar stress via interaction with nucleolin. Scientific Reports 7, Article number: 17761 (2017). Abstract
submitted by kickingbird at Dec, 24, 2017 from Scientific Reports 7, Article number: 17761 (2017) (via http://www.nature.com/articles/s41598-017-18087-2)
The nucleolus is a stress sensor associated with cell cycle progression and a central hub for the replication of pathogenic RNA viruses. However, the role of nucleolus in influenza A virus infection ... W Cheng, etc.,al. Comparison of the three waves of avian influenza A(H7N9) virus circulation since live poultry markets were permanently closed in the main urban areas in Zhejiang Province July, 2014~June, 2017. doi: 10.1111/irv.12532. Abstract
submitted by kickingbird at Dec, 20, 2017 from doi: 10.1111/irv.12532 (via http://onlinelibrary.wiley.com/doi/10.1111/irv.12532/abstrac)
Summary
Background
The sudden increase of the number of human cases infected with avian influenza A(H7N9) virus after September, 2016 raised global concern.
Objectives
To assess the changes of epidemiological ... Luo S, et al. surveillance of live poultry markets for low pathogenic avian influenza viruses in guangxi province, southern china, from 2012~2015. Sci Rep. 2017. Abstract
submitted by kickingbird at Dec, 19, 2017 from Sci Rep. 2017 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29242521/)
Infections with low pathogenic avian influenza viruses (LPAIVs) can be mild or asymptomatic in poultry; however, in humans, LPAIVs can cause severe infections and death, as demonstrated by the H7N9 and ... Herrera-Rodriguez J, Meijerhof T, Niesters HG, Stj. A novel peptide-based vaccine candidate with protective efficacy against influenza A in a mouse model. Virology 2017;515:21-28. Abstract
submitted by kickingbird at Dec, 18, 2017 from Virology 2017;515:21-28 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29223787/)
Current influenza vaccines mainly induce antibody responses to the variable hemagglutinin proteins of the virus strains included in the vaccine. Instead, a broadly protective influenza vaccine should aim ... Ortiz JR, Hickling J, Jones R, Donabedian A, et al. Report on eighth WHO meeting on development of influenza vaccines that induce broadly protective and long-lasting immune responses: Chicago, USA, 23-24 August 2016. Vaccine 2017 Dec 5. Abstract
submitted by kickingbird at Dec, 18, 2017 from Vaccine 2017 Dec 5 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29221895/)
In August 2016, the World Health Organization (WHO) convened the "Eighth meeting on development of influenza vaccines that induce broadly protective and long-lasting immune responses" to discuss the regulatory ... Turkington HL, Juozapaitis M, Tsolakos N, Corrales. Unexpected Functional Divergence of Bat Influenza Virus NS1 Proteins. J Virol 2017 Dec 13. Abstract
submitted by kickingbird at Dec, 18, 2017 from J Virol 2017 Dec 13 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29237829/)
Recently, two influenza A virus (FLUAV) genomes were identified in Central and South American bats. These sequences exhibit notable divergence from classical FLUAV counterparts, and functionally, bat FLUAV ... Chauche C, Nogales A, Zhu H, Goldfarb D, et al. Mammalian adaptation of an avian influenza A virus involves stepwise changes in NS1. J Virol 2017 Dec 13. Abstract
submitted by kickingbird at Dec, 18, 2017 from J Virol 2017 Dec 13 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29237841/)
Influenza A viruses (IAVs) are common pathogens of birds that occasionally establish endemic infections in mammals. The processes and mechanisms that result in IAV mammalian adaptation are poorly understood. ... 7503 items, 20/Page, Page[221/376][|<<] [|<] [221] [222] [223] [224] [225] [226] [227] [228] [229] [230] [>|] [>>|] |
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