McKimm-Breschkin JL, Barrett S, Wong FYK. Identification of Indonesian clade 2.1 highly pathogenic influenza A(H5N1) viruses with N294S and S246N neuraminidase substitutions which further reduce oseltamivir susceptibility. Antiviral Res. 2018 Mar 21. Abstract
submitted by kickingbird at Mar, 29, 2018 from Antiviral Res. 2018 Mar 21 (via https://www.sciencedirect.com/science/article/pii/S016635421)
We have tested the in vitro susceptibility to the neuraminidase (NA) inhibitors of 96 highly pathogenic clade 2.1 A(H5N1) viruses from Indonesia, isolated between 2008 and 2011. HPAI virus samples obtained ... Yang W, Cummings MJ, Bakamutumaho B. Dynamics of Influenza in Tropical Africa: Temperature, Humidity, and Co-circulating (sub)types. Influenza Other Respir Viruses. 2018 Mar 23.. Abstract
submitted by kickingbird at Mar, 29, 2018 from Influenza Other Respir Viruses. 2018 Mar 23. (via https://www.ncbi.nlm.nih.gov/pubmed/29573157)
BACKGROUND: The association of influenza with meteorological variables in tropical climates remains controversial. Here we investigate the impact of weather conditions on influenza in the tropics and factors ... Moore J, Ahmed H, Antia R. High dimensional random walks can appear low dimensional: application to influenza H3N2 evolution. J Theor Biol. 2018 Mar 20. Abstract
submitted by kickingbird at Mar, 29, 2018 from J Theor Biol. 2018 Mar 20 (via https://www.ncbi.nlm.nih.gov/pubmed/29571708)
One important feature of the mammalian immune system is the highly specific binding of antigens to antibodies. Antibodies generated in response to one infection may also provide some level of cross immunity ... Abdul-Cader MS, Ehiremen G, Nagy E, Abdul-Careem. Low pathogenic avian influenza virus infection increases the staining intensity of KUL01+ cells including macrophages yet decrease of the staining intensity of KUL01+ cells using clodronate liposomes. Vet Immunol Immunopathol. 2018 Apr. Abstract
submitted by kickingbird at Mar, 29, 2018 from Vet Immunol Immunopathol. 2018 Apr (via https://www.ncbi.nlm.nih.gov/pubmed/29571516)
The effect of depletion of macrophages using clodronate liposomes as well as macrophage response following viral infections have been studied in various mouse-virus infection models, but they have not ... Nemoto M, Yamanaka T, Bannai H, Tsujimura K, Kokad. Complete Genomic Sequences of H3N8 Equine Influenza Virus Strains Used as Vaccine Strains in Japan. Genome Announc 6:e00172-18. Abstract
submitted by kickingbird at Mar, 29, 2018 from Genome Announc 6:e00172-18 (via http://genomea.asm.org/content/6/12/e00172-18)
We sequenced the eight segments of influenza A virus strains A/equine/Ibaraki/1/2007 and A/equine/Yokohama/aq13/2010, which are strains of the Florida sublineage clades 1 and 2 of the H3N8 subtype equine ... Yang W, Cummings MJ, Bakamutumaho B, Kayiwa J. Transmission dynamics of influenza in two major cities of Uganda. Epidemics. 2018 Mar 19. Abstract
submitted by kickingbird at Mar, 29, 2018 from Epidemics. 2018 Mar 19 (via https://www.sciencedirect.com/science/article/pii/S175543651)
In this paper, we report the epidemic characteristics of the three co-circulating influenza viruses (i.e., A/H1N1, A/H3N2, and B) in two tropical African cities—Kampala and Entebbe, Uganda—over an eight-year ... Wang J, Zeng Y, Xu S, Yang J, et al. A Naturally Occurring Deletion in the Effector Domain of H5N1 Swine Influenza Virus Nonstructural Protein 1 Regulates Viral Fitness and Host Innate Immunity. J Virol 2018 Mar 21. Abstract
submitted by kickingbird at Mar, 26, 2018 from J Virol 2018 Mar 21 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29563291/)
Nonstructural protein 1 (NS1) of influenza A virus regulates innate immune responses via various mechanisms. We previously showed that a naturally occurring deletion (the EALQR motif) in the NS1 effector ... Aljurayyan A, Puksuriwong S, Ahmed M, Sharma R, et. Activation and induction of antigen-specific T follicular helper cells (TFH) play a critical role in LAIV-induced human mucosal anti-influenza antibody response. J Virol 2018 Mar 21. Abstract
submitted by kickingbird at Mar, 26, 2018 from J Virol 2018 Mar 21 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29563292/)
There is increasing interest recently in developing intranasal vaccines against respiratory tract infections. Antibody response is critical in vaccine-induced protection and TFH is considered important ... Watanabe Y, Arai Y, Kawashita N, Ibrahim MS, et al. Characterization of H5N1 influenza virus quasispecies with adaptive hemagglutinin mutations from single-virus infections of human airway cells. J Virol 2018 Mar 21. Abstract
submitted by kickingbird at Mar, 26, 2018 from J Virol 2018 Mar 21 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29563293/)
Transmission of avian influenza (AI) viruses to mammals involves phylogenetic bottlenecks that select small numbers of variants for transmission to new host species. However, little is known about the ... Quan C, Shi W, Yang Y, Yang Y, et al. New threats of H7N9 influenza virus: the spread and evolution of highly and low pathogenic variants with high genomic diversity in Wave Five. J Virol 2018 Mar 21. Abstract
submitted by kickingbird at Mar, 26, 2018 from J Virol 2018 Mar 21 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29563296/)
H7N9 virus has caused five infection waves since it emerged in 2013. The highest number of human cases was seen in Wave Five; however, the underlying reasons have not been thoroughly elucidated. In this ... Jung KI, Pyo CW, Choi SY. Influenza A virus-induced autophagy contributes to enhancement of virus infectivity by SOD1 downregulation in alveolar epithelial cells. Biochem Biophys Res Commun 2018 Mar 16. Abstract
submitted by kickingbird at Mar, 26, 2018 from Biochem Biophys Res Commun 2018 Mar 16 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29548827/)
Infection with influenza A virus (IAV) A/WSN/1933 (H1N1) causes oxidative stress and severe lung injury. We have demonstrated that the generation of reactive oxygen species (ROS) during IAV infection is ... Cao X, Liu X, Zheng S, Xu L, et al.. Isolation and characterization of an avian-origin H3N8 canine influenza virus from a dog in eastern China. Arch Virol 2018 Mar 20. Abstract
submitted by kickingbird at Mar, 26, 2018 from Arch Virol 2018 Mar 20 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29556821/)
Previous studies have shown that dogs are susceptible to influenza A viruses, and the close contact between dogs and humans poses a threat to public health. In 2015, a novel H3N8 influenza virus was isolated ... S. Yamayoshi, etc.,al. Enhanced Replication of Highly Pathogenic Influenza A(H7N9) Virus in Humans. EID Vol 24, No. 4. Abstract
submitted by kickingbird at Mar, 22, 2018 from EID Vol 24, No. 4 (via https://wwwnc.cdc.gov/eid/article/24/4/17-1509_article)
To clarify the threat posed by emergence of highly pathogenic influenza A(H7N9) virus infection among humans, we characterized the viral polymerase complex. Polymerase basic 2–482R, polymerase basic 2–588V, ... Brianne J. Lindsay, etc.,al. Morphological characterization of a plant-made virus-like particle vaccine bearing influenza virus hemagglutinins by electron microscopy. Vaccine 14 March 2018. Abstract
submitted by kickingbird at Mar, 22, 2018 from Vaccine 14 March 2018 (via https://www.sciencedirect.com/science/article/pii/S0264410X1)
Plant-made virus-like particle (VLP) vaccines that display wild-type influenza hemagglutinin (HA) are rapidly advancing through clinical trials. Produced by transient transfection of Nicotiana benthamiana, ... Kathleen A. Stellrecht. Incidence of matrix genes mutations affecting PCR tests among influenza H3N2 clades circulating during the 2014/15 season. Diagnostic Microbiology&Infectious Diseases. Abstract
submitted by kickingbird at Mar, 22, 2018 from Diagnostic Microbiology&Infectious Diseases (via http://www.dmidjournal.com/article/S0732-8893(18)30054-3/ful)
Influenza circulating during the 2014/15 season was associated with significant drift and the emergence of new H3N2 subgroups. It was also known that mutations were accumulating in the WHO-recommended ... Kwang Il Jung, etc.,al. Influenza A virus-induced autophagy contributes to enhancement of virus infectivity by SOD1 downregulation in alveolar epithelial cells. Biochemical and Biophysical Research Communication. Abstract
submitted by kickingbird at Mar, 22, 2018 from Biochemical and Biophysical Research Communication (via https://www.sciencedirect.com/science/article/pii/S0006291X1)
Infection with influenza A virus (IAV) A/WSN/1933 (H1N1) causes oxidative stress and severe lung injury. We have demonstrated that the generation of reactive oxygen species (ROS) during IAV infection is ... Ishiguro N. et al. Clinical effectiveness of four neuraminidase inhibitors(oseltamivir, zanamivir, laninamivir,and peramivir) for children with influenza A and B in the 2014-2015 to 2016-2017 influenza seasons in Japan. J Infect Chemother. 2018 Feb 24. Abstract
submitted by kickingbird at Mar, 20, 2018 from J Infect Chemother. 2018 Feb 24 (via https://www.ncbi.nlm.nih.gov/pubmed/29487035)
The clinical effectiveness of four neuraminidase inhibitors (NAIs) (oseltamivir, zanamivir, laninamivir, and peramivir) for children aged 0 months to 18 years with influenza A and B were investigated in ... Lee IW, etc.,al. Comparison of the virulence and transmissibility of canine H3N2 influenza viruses and characterization of their canine adaptation factors. Emerg Microbes Infect. 2018 Mar 7;7(1):17. Abstract
submitted by kickingbird at Mar, 12, 2018 from Emerg Microbes Infect. 2018 Mar 7;7(1):17 (via https://www.ncbi.nlm.nih.gov/pubmed/29511200)
Recent canine influenza outbreaks have raised concerns about the generation of pathogenic variants that may pose a threat to public health. Here, we examine avian-like H3N2 canine influenza viruses (CIVs) ... Jin H, etc.,al. Evolution of H9N2 avian influenza virus in embryonated chicken eggs with or without homologous vaccine antibodies. BMC Vet Res. 2018 Mar 6;14(1):71.. Abstract
submitted by kickingbird at Mar, 12, 2018 from BMC Vet Res. 2018 Mar 6;14(1):71. (via https://www.ncbi.nlm.nih.gov/pubmed/29510698)
BACKGROUND: Vaccines constitute a unique selective pressure, different from natural selection, drives the evolution of influenza virus. In this study, A/Chicken/Shanghai/F/1998 (H9N2) was continually passaged ... Czako R, Vogel L, Sutton T, Matsuoka Y, et al. H5N2 vaccine viruses on Russian and US live attenuated influenza virus backbones demonstrate similar infectivity, immunogenicity and protection in ferrets. Vaccine 2018 Mar 1.. Abstract
submitted by kickingbird at Mar, 12, 2018 from Vaccine 2018 Mar 1. (via https://www.ncbi.nlm.nih.gov/m/pubmed/29503113/)
The continued detection of zoonotic influenza infections, most notably due to the avian influenza A H5N1 and H7N9 subtypes, underscores the need for pandemic preparedness. Decades of experience with live ... 7508 items, 20/Page, Page[216/376][|<<] [|<] [211] [212] [213] [214] [215] [216] [217] [218] [219] [220] [>|] [>>|] |
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