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2020-1-23 22:03:14

Cov├ęs-Datson EM, et al. A molecularly engineered antiviral banana lectin inhibits fusion and is efficacious against influenza virus infection in vivo. Proc Natl Acad Sci U S A. 2020 Jan 13.  Abstract  
submitted by kickingbird at 7 days ago from Proc Natl Acad Sci U S A. 2020 Jan 13 (via https://www.pnas.org/content/early/2020/01/09/1915152117)
There is a strong need for a new broad-spectrum antiinfluenza therapeutic, as vaccination and existing treatments are only moderately effective. We previously engineered a lectin, H84T banana lectin (H84T), ...

Stoimenov GM, et al. Pathological Changes in Natural Infection of Pheasants with Highly Pathogenic Avian Influenza A (H5N8) in Bulgaria. J Vet Res. 2019 Dec 19;63(4):497-502.  Abstract  
submitted by kickingbird at 8 days ago from J Vet Res. 2019 Dec 19;63(4):497-502 (via https://content.sciendo.com/view/journals/jvetres/63/4/artic)
Introduction: The study of histopathological changes caused by influenza A (H5N8) viral infection in bird species is essential for the understanding of their role in the spread of this highly infectious ...

Simusika P, et al. An evaluation of the Zambia influenza sentinel surveillance system, 2011-2017. BMC Health Serv Res. 2020 Jan 13;20(1):35..  Abstract  
submitted by kickingbird at 8 days ago from BMC Health Serv Res. 2020 Jan 13;20(1):35. (via https://bmchealthservres.biomedcentral.com/articles/10.1186/)
BACKGROUND: Over the past decade, influenza surveillance has been established in several African countries including Zambia. However, information on the on data quality and reliability of established influenza ...

Omi J, et al. The inducible amphisome isolates viral hemagglutinin and defends against influenza A virus infection. Nat Commun. 2020 Jan 9;11(1):162..  Abstract  
submitted by kickingbird at 10 days ago from Nat Commun. 2020 Jan 9;11(1):162. (via https://www.nature.com/articles/s41467-019-13974-w)
The emergence of drug-resistant influenza type A viruses (IAVs) necessitates the development of novel anti-IAV agents. Here, we target the IAV hemagglutinin (HA) protein using multivalent peptide library ...

Li B, et al. Genome-wide CRISPR screen identifies host dependency factors for influenza A virus infection. Nat Commun. 2020 Jan 9;11(1):164..  Abstract  
submitted by kickingbird at 10 days ago from Nat Commun. 2020 Jan 9;11(1):164. (via https://www.nature.com/articles/s41467-019-13965-x)
Host dependency factors that are required for influenza A virus infection may serve as therapeutic targets as the virus is less likely to bypass them under drug-mediated selection pressure. Previous attempts ...

Xu S, et al. Comparative Pathogenicity and Transmissibility of Pandemic H1N1, Avian H5N1, and Human H7N9 Influenza Viruses in Tree Shrews. Front Microbiol. 2019 Dec 20;10:2955..  Abstract  
submitted by kickingbird at 10 days ago from Front Microbiol. 2019 Dec 20;10:2955. (via https://www.frontiersin.org/articles/10.3389/fmicb.2019.0295)
Influenza A viruses (IAVs) continuously challenge the poultry industry and human health. Studies of IAVs are still hampered by the availability of suitable animal models. Chinese tree shrews (Tupaia belangeri ...

Cheng KL, et al. Avian Influenza Virus Detection Rates in Poultry and Environment at Live Poultry Markets, Guangdong, China. Emerg Infect Dis. 2020 Mar 17;26(3).  Abstract  
submitted by kickingbird at 10 days ago from Emerg Infect Dis. 2020 Mar 17;26(3) (via https://wwwnc.cdc.gov/eid/article/26/3/19-0888_article)
We report the use of environmental samples to assess avian influenza virus activity in chickens at live poultry markets in China. Results of environmental and chicken samples correlate moderately well. ...

Gao C, et al. Association Between Cardiac Injury and Mortality in Hospitalized Patients Infected With Avian Influenza A (H7N9) Virus. Crit Care Med. 2020 Jan 9..  Abstract  
submitted by kickingbird at 10 days ago from Crit Care Med. 2020 Jan 9. (via https://journals.lww.com/ccmjournal/Abstract/onlinefirst/Ass)
OBJECTIVES: To evaluate the prevalence of cardiac injury and its association with mortality in hospitalized patients infected with avian influenza A (H7N9) virus.DESIGN: Retrospective cohort study.SETTING: ...

Reeves AB, et al. Field-based method for assessing duration of infectivity for influenza A viruses in the environment. J Virol Methods. 2020 Jan 7:113818..  Abstract  
submitted by kickingbird at 10 days ago from J Virol Methods. 2020 Jan 7:113818. (via https://www.sciencedirect.com/science/article/abs/pii/S01660)
Understanding influenza A virus (IAV) persistence in wetlands is limited by a paucity of field studies relating to the maintenance of infectivity over time. The duration of IAV infectivity in water has ...

Joshi SR, Sharma A, Kim GH, Jang J. Low cost synthesis of reduced graphene oxide using biopolymer for influenza virus sensor. Mater Sci Eng C Mater Biol Appl. 2020 Mar;108:1104.  Abstract  
submitted by kickingbird at 10 days ago from Mater Sci Eng C Mater Biol Appl. 2020 Mar;108:1104 (via https://www.sciencedirect.com/science/article/abs/pii/S09284)
A biocompatible, cost-effective, and scalable reduced graphene oxide (rGO) film was obtained from shellac using thermal treatment and its structural, chemical, and electrical properties were investigated. ...

Poh ZW, et al. Modification of neutralizing epitopes of hemagglutinin for the development of broadly protective H9N2 vaccine.. Vaccine. 2020 Jan 7.  Abstract  
submitted by kickingbird at 10 days ago from Vaccine. 2020 Jan 7 (via https://www.sciencedirect.com/science/article/pii/S0264410X1)
The H9N2 avian influenza viruses cause significant economic losses in poultry worldwide and could potentially cause human pandemic. Currently, the available vaccines have limited efficacy due to antigenic ...

Masuda T, et al. An influenza-derived membrane tension-modulating peptide regulates cell movement and morphology via actin remodeling. Commun Biol. 2019 Jun 26;2(1):243.  Abstract  
submitted by kickingbird at 10 days ago from Commun Biol. 2019 Jun 26;2(1):243 (via https://www.nature.com/articles/s42003-019-0486-3)
Tension in cell membranes is closely related to various cellular events, including cell movement and morphogenesis. Therefore, modulation of membrane tension can be a new approach for manipulating cellular ...

Guo J, et al. Development and fit-for-purpose verification of an LC-MS method for quantitation of hemagglutinin and neuraminidase proteins in influenza virus-like particle vaccine candidates. Anal Biochem. 2020 Jan 8:113577..  Abstract  
submitted by kickingbird at 10 days ago from Anal Biochem. 2020 Jan 8:113577. (via https://www.sciencedirect.com/science/article/pii/S000326971)
Recombinant influenza Virus-Like Particle (VLP) vaccines are promising vaccine candidates to prevent influenza, contain two major viral antigenic glycoproteins, Hemagglutinin (HA) and Neuraminidase (NA), ...

Khalil AM, et al. Transition in genetic constellations of H3N8 and H4N6 low-pathogenic avian influenza viruses isolated from an overwintering site in Japan throughout different winter seasons. Arch Virol. 2020 Jan 10..  Abstract  
submitted by kickingbird at 10 days ago from Arch Virol. 2020 Jan 10. (via https://link.springer.com/article/10.1007%2Fs00705-019-04519)
The Izumi plain in Kagoshima Prefecture, Japan, is an overwintering site for migratory ducks and endangered cranes. We have surveyed avian influenza viruses (AIVs) in this area since 2012 and isolated ...

Luo W, et al. The fit of codon usage of human-isolated avian influenza A viruses to human. Infect Genet Evol. 2020 Jan 6:104181.  Abstract  
submitted by kickingbird at 12 days ago from Infect Genet Evol. 2020 Jan 6:104181 (via https://www.sciencedirect.com/science/article/abs/pii/S15671)
Avian influenza A viruses (AIVs) classify into 18 hemagglutinin (HA) and 11 neuraminidase (NA) subtypes. Even though H1N1 and H3N2 subtypes usually circulate among humans leading to infection, occasionally, ...

Choi EJ1, et al. The effect of mutations derived from mouse-adapted H3N2 seasonal influenza A virus to pathogenicity and host adaptation. PLoS One. 2020 Jan 9;15(1):e0227516..  Abstract  
submitted by kickingbird at 12 days ago from PLoS One. 2020 Jan 9;15(1):e0227516. (via https://journals.plos.org/plosone/article?id=10.1371/journal)
Elucidating the genetic basis of influenza A viruses (IAVs) is important to understand which mutations will determine the virulence and the host range of mammals. Here, seasonal H3N2 influenza was adapted ...

Kakogawa M, et al. Epidemiologic Survey of Avian Influenza Virus Infection in Shorebirds Captured in Hokkaido, Japan. J Wildl Dis. 2020 Jan.  Abstract  
submitted by kickingbird at 12 days ago from J Wildl Dis. 2020 Jan (via https://www.jwildlifedis.org/doi/10.7589/2019-02-052)
There is limited information about virus epidemiology of shorebirds (family Charadriidae and Scolopacidae) in the East Asia-Australasia flyway. We investigated the prevalence of avian influenza viruses ...

Xia C, et al. PARP1 enhances influenza A virus propagation by facilitating degradation of host type I interferon receptor. J Virol. 2020 Jan 8.  Abstract  
submitted by kickingbird at 12 days ago from J Virol. 2020 Jan 8 (via https://jvi.asm.org/content/early/2020/01/03/JVI.01572-19)
Influenza A virus (IAV) utilizes multiple strategies to confront or evade host type I interferon (IFN)-mediated antiviral responses in order to enhance its own propagation within the host. One such strategy ...

Rivailler P, Moisy D, Naffakh N. Multiple hosts and Influenza A viruses genetic mixing. Virologie (Montrouge). 2013 Dec 1;17(6):387-400..  Abstract  
submitted by kickingbird at 12 days ago from Virologie (Montrouge). 2013 Dec 1;17(6):387-400. (via https://www.ncbi.nlm.nih.gov/pubmed/31910604)
Influenza A viruses have a segmented, negative-stranded RNA genome. These viruses are classified according to the antigenic properties of the two glycoproteins, expressed on the surface of the virus particles, ...

Cai M, et al. The R251K Substitution in Viral Protein PB2 Increases Viral Replication and Pathogenicity of Eurasian Avian-like H1N1 Swine Influenza Viruses. Viruses. 2020 Jan 2;12(1)..  Abstract  
submitted by kickingbird at 14 days ago from Viruses. 2020 Jan 2;12(1). (via https://www.mdpi.com/1999-4915/12/1/52)
The Eurasian avian-like swine (EA) H1N1 virus has affected the Chinese swine industry, and human infection cases have been reported occasionally. However, little is known about the pathogenic mechanism ...

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