Berger KA, et al. The Geographic Variation of Surveillance and Zoonotic Spillover Potential of Influenza Viruses in Domestic Poultry and Swine. Open Forum Infect Dis. 2018 Nov 27. Abstract
submitted by kickingbird at 12 days ago from Open Forum Infect Dis. 2018 Nov 27 (via https://www.ncbi.nlm.nih.gov/pubmed/30619908)
Background: Avian and swine influenza viruses circulate worldwide and pose threats to both animal and human health. The design of global surveillance strategies is hindered by information gaps on the geospatial ...
Dadak M, et al. Varying Patterns of CNS Imaging in Influenza A Encephalopathy in Childhood. Clin Neuroradiol. 2019 Jan 4. Abstract
submitted by kickingbird at 14 days ago from Clin Neuroradiol. 2019 Jan 4 (via https://www.ncbi.nlm.nih.gov/pubmed/30610262)
PURPOSE: The brain imaging findings in children with neurological complications associated with influenza A infections are presented and analyzed and pathological imaging changes including atypical intracerebral ...
Peci A, et al. Effect of absolute and relative humidity, temperature and wind speed on influenza activity in Toronto, Canada. Appl Environ Microbiol. 2019 Jan 4. Abstract
submitted by kickingbird at 14 days ago from Appl Environ Microbiol. 2019 Jan 4 (via https://www.ncbi.nlm.nih.gov/pubmed/30610079)
The occurrence of influenza in different climates is shown to be associated with multiple meteorological factors. Incidence of influenza has been reported to increase during rainy seasons in tropical climates ...
Peretz A, Azrad M, Blum A. Influenza virus and Atherosclerosis. QJM. 2019 Jan 3.. Abstract
submitted by kickingbird at 14 days ago from QJM. 2019 Jan 3. (via https://www.ncbi.nlm.nih.gov/pubmed/30605546)
Influenza viruses infect the upper respiratory system, causing usually a self-limited disease with mild respiratory symptoms. Acute lung injury, pulmonary microvascular leakage and cardiovascular collapse ...
Yoo BW, Kim CO, Izu A, Arora AK, Heijnen E. Phase 4, Post-Marketing Safety Surveillance of the MF59-Adjuvanted Influenza Vaccines FLUAD? and VANTAFLU? in South Korean Subjects Aged ≥65 Years. Infect Chemother. 2018 Dec;50(4):301-310. Abstract
submitted by kickingbird at 14 days ago from Infect Chemother. 2018 Dec;50(4):301-310 (via https://www.ncbi.nlm.nih.gov/pubmed/30600653)
BACKGROUD: Influenza vaccination is recommended for adults aged ≥65 years as they are at high risk of significant morbidity and mortality. This open-label, multicenter, post-marketing surveillance study ...
Saito S, et al. Development and evaluation of a new real-time RT-PCR assay for detecting the latest H9N2 influenza viruses capable of causing human infection. Microbiol Immunol. 2019 Jan 1.. Abstract
submitted by kickingbird at Jan, 4, 2019 from Microbiol Immunol. 2019 Jan 1. (via https://www.ncbi.nlm.nih.gov/pubmed/30599081)
The H9N2 subtype of avian influenza A viruses (AIVs) has spread among domestic poultry and wild bird worldwide. H9N2 AIV is sporadically transmitted to humans from avian species. A total of 42 laboratory-confirmed ...
Zhou X, Yin R, Kwoh CK, Zheng J. A context-free encoding scheme of protein sequences for predicting antigenicity of diverse influenza A viruses. BMC Genomics. 2018 Dec 31;19. Abstract
submitted by kickingbird at Jan, 4, 2019 from BMC Genomics. 2018 Dec 31;19 (via https://www.ncbi.nlm.nih.gov/pubmed/30598102)
BACKGROUND: The evolution of influenza A viruses leads to the antigenic changes. Serological diagnosis of the antigenicity is usually labor-intensive, time-consuming and not suitable for early-stage detection. ...
Peng Q, et al. Impact of the variations in potential glycosylation sites of the hemagglutinin of H9N2 influenza virus. Virus Genes. 2018 Dec 29.. Abstract
submitted by kickingbird at Jan, 1, 2019 from Virus Genes. 2018 Dec 29. (via https://www.ncbi.nlm.nih.gov/pubmed/30594968)
Variations in the potential glycosylation sites were observed in hemagglutinin (HA) sequences of H9N2 avian influenza virus isolated in China, deposited in the Influenza Virus Resource of NCBI before 2017, ...
Li Z, et al. A novel linear epitope crossing Group 1 and Group 2 influenza A viruses located in the helix A of HA2 derived from H7N9. Vet Microbiol. 2019 Jan;228:39-44.. Abstract
submitted by kickingbird at Dec, 30, 2018 from Vet Microbiol. 2019 Jan;228:39-44. (via https://www.ncbi.nlm.nih.gov/pubmed/30593378)
In this research, four monoclonal antibodies (mAbs) were first generated as an immunogen by using the GST fusion protein that carries the fusion peptide and helix A derived from H7N9 influenza A virus ...
Wang Z, et al. Pre-exposure with influenza A virus A/WSN/1933(H1N1) resulted in viral shedding reduction from pigs challenged with either swine H1N1 or H3N2 virus. Vet Microbiol. 2019 Jan;228:26-31. Abstract
submitted by kickingbird at Dec, 30, 2018 from Vet Microbiol. 2019 Jan;228:26-31 (via https://www.ncbi.nlm.nih.gov/pubmed/30593376)
There is an urgent need to develop a broad-spectrum vaccine that can effectively prevent or eliminate the spread of co-circulating swine influenza virus strains in multiple lineages or subtypes. We describe ...
An SH, Lee CY, Choi JG, Lee YJ, Kim JH, Kwon HJ. Generation of highly productive and mammalian nonpathogenic recombinant H9N2 avian influenza viruses by optimization of 3´end promoter and NS genome. Vet Microbiol. 2019 Jan;228:213-218.. Abstract
submitted by kickingbird at Dec, 30, 2018 from Vet Microbiol. 2019 Jan;228:213-218. (via https://www.ncbi.nlm.nih.gov/pubmed/30593370)
We developed A/PR/8/34 (PR8) virus-based reverse genetics system in which six internal genes of PR8 and attenuated hemagglutinin and intact neuraminidase genes of field avian influenza viruses (AIVs) have ...
Fleming-Canepa X, et al. Duck innate immune responses to high and low pathogenicity H5 avian influenza viruses. Vet Microbiol. 2019 Jan;228:101-111. Abstract
submitted by kickingbird at Dec, 30, 2018 from Vet Microbiol. 2019 Jan;228:101-111 (via https://www.ncbi.nlm.nih.gov/pubmed/30593354)
Ducks are the reservoir host of influenza A viruses, and are permissive for replication of most strains, yet can elicit robust innate immune responses to highly pathogenic strains. Tissue tropism and viral ...
Yu Z, He H, Cheng K, Wu J, Gao Y, Chen W, et al. Genetic characterization of an H13N2 low pathogenic avian influenza virus isolated from gulls in China. Transbound Emerg Dis. 2018 Dec 22.. Abstract
submitted by kickingbird at Dec, 25, 2018 from Transbound Emerg Dis. 2018 Dec 22. (via https://www.ncbi.nlm.nih.gov/pubmed/30578616)
Low pathogenic avian influenza viruses circulate in wild birds but are occasionally transmitted to other species, including poultry, mammals, and humans. To date, infections with low pathogenic avian influenza ...
Rahim MN, Klewes L, Zahedi-Amiri A, et al. Global Interactomics Connect Nuclear Mitotic Apparatus Protein NUMA1 to Influenza Virus Maturation. Viruses. 2018 Dec 19;10(12). Abstract
submitted by kickingbird at Dec, 24, 2018 from Viruses. 2018 Dec 19;10(12) (via https://www.ncbi.nlm.nih.gov/pubmed/30572664)
Influenza A virus (IAV) infections remain a major human health threat. IAV has enormous genetic plasticity and can rapidly escape virus-targeted anti-viral strategies. Thus, there is increasing interest ...
Skibinski DAG, et al. Induction of Human T-cell and Cytokine Responses Following Vaccination with a Novel Influenza Vaccine. Sci Rep. 2018 Dec 20;8(1):18007. Abstract
submitted by kickingbird at Dec, 24, 2018 from Sci Rep. 2018 Dec 20;8(1):18007 (via https://www.ncbi.nlm.nih.gov/pubmed/30573748)
Cell mediated immunity plays a vital role in defense against influenza infection in humans. Less is known about the role of vaccine-induced cell mediated immunity and the cytokine responses elicited. We ...
Pawestri HA, Nugraha AA, Hariastuti NI, Setiawaty. Detection of neuraminidase inhibitor-resistant influenza A (H1N1)pdm09 viruses obtained from influenza surveillance in Indonesia. SAGE Open Med. 2018 Dec 10;6:2050312118818293. Abstract
submitted by kickingbird at Dec, 24, 2018 from SAGE Open Med. 2018 Dec 10;6:2050312118818293 (via https://www.ncbi.nlm.nih.gov/pubmed/30574303)
Background: Influenza antiviral resistance has been shown to occur in many countries and is commonly found in influenza A(H1N1)pdm09 and A(H3N2). In this study, we monitored and investigated the neuraminidase ...
Briand FX, et al. Identification of a Divergent Avian Influenza H3N2 Virus from Domestic Ducks in France. Microbiol Resour Announc. 2018 Dec 13;7(23). Abstract
submitted by kickingbird at Dec, 24, 2018 from Microbiol Resour Announc. 2018 Dec 13;7(23) (via https://www.ncbi.nlm.nih.gov/pubmed/30574576)
An avian influenza H3N2 virus was isolated from domestic ducks in France in 2016. Although this French H3N2 virus possesses traits of an avian virus, the genetic distances observed for hemagglutinin (HA) ...
Yoshihara K, et al. Influenza B associated Paediatric Acute Respiratory Infection Hospitalization in Central Vietnam. Influenza Other Respir Viruses. 2018 Dec 21. Abstract
submitted by kickingbird at Dec, 24, 2018 from Influenza Other Respir Viruses. 2018 Dec 21 (via https://www.ncbi.nlm.nih.gov/pubmed/30575288)
BACKGROUND: Influenza B is one of the major etiologies for acute respiratory infections (ARI) among children worldwide; however, its clinical-epidemiological information is limited. We aimed to investigate ...
Yin R, Tran VH, Zhou X, Zheng J, Kwoh CK. Predicting antigenic variants of H1N1 influenza virus based on epidemics and pandemics using a stacking model. PLoS One. 2018 Dec 21;13(12):e0207777.. Abstract
submitted by kickingbird at Dec, 24, 2018 from PLoS One. 2018 Dec 21;13(12):e0207777. (via https://www.ncbi.nlm.nih.gov/pubmed/30576319)
H1N1 is the earliest emerging subtype of influenza A viruses with available genomic sequences, has caused several pandemics and seasonal epidemics, resulting in millions of deaths and enormous economic ...
Hong BT, Cheng YE, Cheng TJ, Fang JM. Boronate, trifluoroborate, sulfone, sulfinate and sulfonate congeners of oseltamivir carboxylic acid: Synthesis and anti-influenza activity. Eur J Med Chem. 2018 Dec 13;163:710-721. Abstract
submitted by kickingbird at Dec, 24, 2018 from Eur J Med Chem. 2018 Dec 13;163:710-721 (via https://www.ncbi.nlm.nih.gov/pubmed/30576902)
Tamiflu readily undergoes endogenous hydrolysis to give oseltamivir carboxylic acid (OC) as the active anti-influenza agent to inhibit the viral neuraminidase (NA). GOC is derived from OC by replacing ...
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