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2022-7-3 10:27:14
Article

Cheng J, Tao J, Li B, Shi Y, Liu H. Swine influenza virus triggers ferroptosis in A549 cells to enhance virus replication. Virol J. 2022 Jun 17;19(1):104.  Abstract  
submitted by kickingbird at 10 days ago from Virol J. 2022 Jun 17;19(1):104 (via https://virologyj.biomedcentral.com/articles/10.1186/s12985-)
Background: Recently, Influenza A virus (IAV) has been shown to activate several programmed cell death pathways that play essential roles in host defense. Indeed, cell death caused by viral infection may ...

Paul R, Han D, DeDoncker E, Prieto D. Dynamic downscaling and daily nowcasting from influenza surveillance data. Stat Med. 2022 Jun 19.  Abstract  
submitted by kickingbird at 10 days ago from Stat Med. 2022 Jun 19 (via https://onlinelibrary.wiley.com/doi/10.1002/sim.9502)
Real-time trends from surveillance data are important to assess and develop preparedness for influenza outbreaks. The overwhelming testing demand and limited capacity of testing laboratories for viral ...

Canaday LM, Resnick JD, Liu H, Powell H, McCoy AM,. HA and M2 sequences alter the replication of 2013-16 H1 live attenuated influenza vaccine infection in human nasal epithelial cell cultures. Vaccine. 2022 Jun 16:S0264-410X(22)00733-2.  Abstract  
submitted by kickingbird at 10 days ago from Vaccine. 2022 Jun 16:S0264-410X(22)00733-2 (via https://www.sciencedirect.com/science/article/pii/S0264410X2)
From 2013 to 2016, the H1N1 component of live, attenuated influenza vaccine (LAIV) performed very poorly in contrast to the inactivated influenza vaccine. We utilized a primary, differentiated human nasal ...

Pohlmann A, King J, Fusaro A, Zecchin B, Banyard A. Has Epizootic Become Enzootic? Evidence for a Fundamental Change in the Infection Dynamics of Highly Pathogenic Avian Influenza in Europe, 2021. mBio. 2022 Jun 21:e0060922.  Abstract  
submitted by kickingbird at 10 days ago from mBio. 2022 Jun 21:e0060922 (via https://journals.asm.org/doi/10.1128/mbio.00609-22)
Phylogenetic evidence from the recent resurgence of high-pathogenicity avian influenza (HPAI) virus subtype H5N1, clade 2.3.4.4b, observed in European wild birds and poultry since October 2021, suggests ...

Dean DA, Klechka L, Hossain E, Parab AR, Eaton K,. Spatial Metabolomics Reveals Localized Impact of Influenza Virus Infection on the Lung Tissue Metabolome. mSystems. 2022 Jun 22:e0035322.  Abstract  
submitted by kickingbird at 10 days ago from mSystems. 2022 Jun 22:e0035322 (via https://journals.asm.org/doi/10.1128/msystems.00353-22)
The influenza virus (IAV) is a major cause of respiratory disease, with significant infection increases in pandemic years. Vaccines are a mainstay of IAV prevention but are complicated by IAV's vast strain ...

Berhane Y, Joseph T, Lung O, Embury-Hyatt C, Xu W,. Isolation and Characterization of Novel Reassortant Influenza A(H10N7) Virus in a Harbor Seal, British Columbia, Canada. Emerg Infect Dis. 2022 Jul;28(7):1480-1484.  Abstract  
submitted by kickingbird at 10 days ago from Emerg Infect Dis. 2022 Jul;28(7):1480-1484 (via https://wwwnc.cdc.gov/eid/article/28/7/21-2302_article)
We isolated a novel reassortant influenza A(H10N7) virus from a harbor seal in British Columbia, Canada, that died from bronchointerstitial pneumonia. The virus had unique genome constellations involving ...

Sun W, Cheng SSM, Lam KNT, Kwan TC, Wong RWK, Lau. Natural Reassortment of Eurasian Avian-Like Swine H1N1 and Avian H9N2 Influenza Viruses in Pigs, China. Emerg Infect Dis. 2022 Jul;28(7):1509-1512.  Abstract  
submitted by kickingbird at 10 days ago from Emerg Infect Dis. 2022 Jul;28(7):1509-1512 (via https://wwwnc.cdc.gov/eid/article/28/7/22-0642_article)
Several zoonotic influenza A viruses detected in humans contain genes derived from avian H9N2 subtypes. We uncovered a Eurasian avian-like H1N1 swine influenza virus with polymerase basic 1 and matrix ...

Moise L, Meyers LM, Jang H, Grizotte-Lake M, Boyle. Novel H7N9 influenza immunogen design enhances mobilization of seasonal influenza T cell memory in H3N2 pre-immune mice. Hum Vaccin Immunother. 2022 Jun 15:2082191.  Abstract  
submitted by kickingbird at 15 days ago from Hum Vaccin Immunother. 2022 Jun 15:2082191 (via https://www.tandfonline.com/doi/full/10.1080/21645515.2022.2)
Strategies that improve influenza vaccine immunogenicity are critical for the development of vaccines for pandemic preparedness. Hemagglutinin (HA)-specific CD4+ T cell epitopes support protective B cell ...

Zhu R, Xu S, Sun W, Li Q, Wang S, Shi H, Liu X. HA gene amino acid mutations contribute to antigenic variation and immune escape of H9N2 influenza virus. Vet Res. 2022 Jun 15;53(1):43.  Abstract  
submitted by kickingbird at 15 days ago from Vet Res. 2022 Jun 15;53(1):43 (via https://veterinaryresearch.biomedcentral.com/articles/10.118)
Based on differences in the amino acid sequence of the protein haemagglutinin (HA), the H9N2 avian influenza virus (H9N2 virus) has been clustered into multiple lineages, and its rapidly ongoing evolution ...

Berry I, Rahman M, Flora MS, Shirin T, Alamgir ASM. Seasonality of influenza and coseasonality with avian influenza in Bangladesh, 2010-19: a retrospective, time-series analysis. Lancet Glob Health. 2022 Jun 13:S2214-109X(22)0021.  Abstract  
submitted by kickingbird at 15 days ago from Lancet Glob Health. 2022 Jun 13:S2214-109X(22)0021 (via https://www.thelancet.com/journals/langlo/article/PIIS2214-1)
Background: Seasonal and avian influenza viruses circulate among human and poultry populations in Bangladesh. However, the epidemiology of influenza is not well defined in this setting. We aimed to characterise ...

Zhuang X, Chen L, Yang S, Xia S, Xu Z, Zhang T, Ze. R848 Adjuvant Laden With Self-Assembled Nanoparticle-Based mRNA Vaccine Elicits Protective Immunity Against H5N1 in Mice. Front Immunol. 2022 May 31;13:836274.  Abstract  
submitted by kickingbird at 15 days ago from Front Immunol. 2022 May 31;13:836274 (via https://www.frontiersin.org/articles/10.3389/fimmu.2022.8362)
In order to perfect the design strategy of messenger RNA (mRNA) vaccines against the H5N1 influenza virus, we investigated whether different antigen designs and the use of adjuvants could improve the immune ...

Yoo DS, Chun BC, Hong K, Kim J. Risk Prediction of Three Different Subtypes of Highly Pathogenic Avian Influenza Outbreaks in Poultry Farms: Based on Spatial Characteristics of Infected Premises in South Korea. Front Vet Sci. 2022 May 31;9:897763.  Abstract  
submitted by kickingbird at 15 days ago from Front Vet Sci. 2022 May 31;9:897763 (via https://www.frontiersin.org/articles/10.3389/fvets.2022.8977)
From 2003 to 2017, highly pathogenic avian influenza (HPAI) epidemics, particularly H5N1, H5N8, and H5N6 infections in poultry farms, increased in South Korea. More recently, these subtypes of HPAI virus ...

Castillo-Rodríguez L, Malo-Sánchez D, Díaz-Jiménez. Economic costs of severe seasonal influenza in Colombia, 2017-2019: A multi-center analysis. PLoS One. 2022 Jun 17;17(6):e0270086.  Abstract  
submitted by kickingbird at 15 days ago from PLoS One. 2022 Jun 17;17(6):e0270086 (via https://journals.plos.org/plosone/article?id=10.1371/journal)
Objective: To estimate the economic burden of Severe Acute Respiratory Infection (SARI) in lab-confirmed influenza patients from a low-income country setting such as Colombia.Methods: A bottom-up costing ...

Cui P, Shi J, Wang C, Zhang Y, Xing X, Kong H, Yan. Global dissemination of H5N1 influenza viruses bearing the clade 2.3.4.4b HA gene and biologic analysis of the ones detected in China. Emerg Microbes Infect. 2022 Jun 14:1-41.  Abstract  
submitted by kickingbird at Jun, 15, 2022 from Emerg Microbes Infect. 2022 Jun 14:1-41 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2022.2)
H5N1 avian influenza viruses bearing the clade 2.3.4.4b hemagglutinin gene have been widely circulating in wild birds and are responsible for the loss of over 70 million domestic poultry in Europe, Africa, ...

Lublin A, Thie N, Shkoda I, Simanov L, Bar-Gal GK,. First detection of avian influenza subtype H4N6 in Israel, in a wild mallard (Anas platyrhynchos). Transbound Emerg Dis. 2022 Jun 10.  Abstract  
submitted by kickingbird at Jun, 12, 2022 from Transbound Emerg Dis. 2022 Jun 10 (via https://onlinelibrary.wiley.com/doi/10.1111/tbed.14610)
Avian influenza viruses (AIV) are a worldwide threat to animal and human health. As wild waterfowl circulate and spread these viruses around the world, investigations of AIV prevalence in wild populations ...

Lean FZX, Vitores AG, Reid SM, Banyard AC, Brown I. Gross pathology of high pathogenicity avian influenza virus H5N1 2021-2022 epizootic in naturally infected birds in the United Kingdom. One Health. 2022 Apr 27;14:100392.  Abstract  
submitted by kickingbird at Jun, 12, 2022 from One Health. 2022 Apr 27;14:100392 (via https://www.sciencedirect.com/science/article/pii/S235277142)
High pathogenicity avian influenza virus (HPAIV) clade 2.3.4.4b has re-emerged in the United Kingdom in 2021-2022 winter season, with over 90 cases of HPAIV detected among poultry and captive birds in ...

Li J, Zhang L, Bao L, Wang Y, Qiu L, Hu J, Tang R,. A broadly neutralizing human monoclonal antibody against the hemagglutinin of avian influenza virus H7N9. Chin Med J (Engl). 2022 Apr 5;135(7):799-805.  Abstract  
submitted by kickingbird at Jun, 9, 2022 from Chin Med J (Engl). 2022 Apr 5;135(7):799-805 (via https://journals.lww.com/cmj/Fulltext/2022/04050/A_broadly_n)
Background: The new emerging avian influenza A H7N9 virus, causing severe human infection with a mortality rate of around 41%. This study aims to provide a novel treatment option for the prevention and ...

Scheibner D, Breithaupt A, Luttermann C, Blaurock. Genetic Determinants for Virulence and Transmission of the Panzootic Avian Influenza Virus H5N8 Clade 2.3.4.4 in Pekin Ducks. J Virol. 2022 Jun 7:e0014922.  Abstract  
submitted by kickingbird at Jun, 9, 2022 from J Virol. 2022 Jun 7:e0014922 (via https://journals.asm.org/doi/10.1128/jvi.00149-22)
Waterfowl is the natural reservoir for avian influenza viruses (AIV), where the infection is mostly asymptomatic. In 2016, the panzootic high pathogenicity (HP) AIV H5N8 of clade 2.3.4.4B (designated H5N8-B) ...

Castro-Sanguinetti GR, Marques Simas PV, Apaza-Chi. Genetic subtyping and phylogenetic analysis of HA and NA from avian influenza virus in wild birds from Peru reveals unique features among circulating strains in America. PLoS One. 2022 Jun 7;17(6):e0268957.  Abstract  
submitted by kickingbird at Jun, 9, 2022 from PLoS One. 2022 Jun 7;17(6):e0268957 (via https://journals.plos.org/plosone/article?id=10.1371/journal)
Avian influenza virus (AIV) represents a major concern with productive implications in poultry systems but it is also a zoonotic agent that possesses an intrinsic pandemic risk. AIV is an enveloped, negative-sense ...

Pawar SD, Keng SS, Kode SS, Tare DS, Singh DK, Mul. A novel reassortant avian influenza H4N6 virus isolated from an environmental sample during a surveillance in Maharashtra, India. Indian J Med Res. 2021 Jun;154(6):871-887.  Abstract  
submitted by kickingbird at Jun, 7, 2022 from Indian J Med Res. 2021 Jun;154(6):871-887 (via https://journals.lww.com/ijmr/Fulltext/2021/12000/A_novel_re)
Background & objectives: Low pathogenic avian influenza (LPAI) viruses cause mild clinical illness in domestic birds. Migratory birds are a known reservoir for all subtypes of avian influenza (AI) viruses. ...

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