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Boumart Z, et al. Pathogenicity and Full Genome Sequencing of the Avian Influenza H9N2 Moroccan Isolate 2016. Avian Dis. 2018 Nov 16;63(1):24-30.  Abstract  
submitted by kickingbird at Jul, 2, 2019 from Avian Dis. 2018 Nov 16;63(1):24-30 (via https://bioone.org/journals/Avian-Diseases/volume-63/issue-1)
In Morocco in early 2016, a low pathogenic avian influenza virus serotype H9N2 caused large economic losses to the poultry industry, with specific clinical symptoms and high mortality rates on infected ...

Mu?oz-Aguayo J, et al. Environmental Sampling for Influenza A Viruses in Turkey Barns. Avian Dis. 2018 Nov 9;63(1):17-23.  Abstract  
submitted by kickingbird at Jul, 2, 2019 from Avian Dis. 2018 Nov 9;63(1):17-23 (via https://bioone.org/journals/Avian-Diseases/volume-63/issue-1)
We have examined a variety of sampling strategies for detecting pathogens in turkey flocks undergoing infections with low pathogenicity avian influenza virus (LPAIV). We found that viral RNA was widely ...

Guo F, et al. Adaptive Evolution of Human-Isolated H5Nx Avian Influenza A Viruses. Front Microbiol. 2019 Jun 12;10:1328.  Abstract  
submitted by kickingbird at Jul, 2, 2019 from Front Microbiol. 2019 Jun 12;10:1328 (via https://www.frontiersin.org/articles/10.3389/fmicb.2019.0132)
Avian influenza A viruses (AIVs) H5N1, first identified in 1996, are highly pathogenic in domestic poultry and continue to occasionally infect humans. In this study, we sought to identify genetic changes ...

Spackman E, et al. Clade 2.3.4.4 H5 North American Highly Pathogenic Avian Influenza Viruses Infect, but Do Not Cause Clinical Signs in, American Black Ducks (Anas rubripes).. Avian Dis. 2019 Jan 18;63(2):366-370.  Abstract  
submitted by kickingbird at Jul, 2, 2019 from Avian Dis. 2019 Jan 18;63(2):366-370 (via https://www.ncbi.nlm.nih.gov/pubmed/31251539)
Highly pathogenic avian influenza virus (HPAIV) from the goose/Guangdong/1996 clade 2.3.4.4 H5 lineage spread from Asia into North America in 2014, most likely by wild bird migrations. Although several ...

Chen X, Li C, Sun HT, Ma J, Qi Y, Qin SY. Prevalence of avian influenza viruses and their associated antibodies in wild birds in China: A systematic review and meta-analysis. Microb Pathog. 2019 Jun 26:103613.  Abstract  
submitted by kickingbird at Jul, 2, 2019 from Microb Pathog. 2019 Jun 26:103613 (via https://www.sciencedirect.com/science/article/pii/S088240101)
Avian influenza viruses (AIVs) in wild birds pose a pandemic threat to humans and to the poultry industry. To assess AIV and AIV antibody prevalence in wild birds in China, a systematic review and meta-analysis ...

He CQ, He M, He HB, Wang HM, Ding NZ. The matrix segment of the "Spanish flu" virus originated from intragenic recombination between avian and human influenza A viruses. Transbound Emerg Dis. 2019 Jun 26.  Abstract  
submitted by kickingbird at Jun, 28, 2019 from Transbound Emerg Dis. 2019 Jun 26 (via https://onlinelibrary.wiley.com/doi/abs/10.1111/tbed.13282)
The 1918 Spanish flu virus has claimed more than 50 million lives. However, the mechanism of its high pathogenicity remains elusive; and the origin of the virus is controversial. The matrix (M) segment ...

Mine J, et al. Phylogeographic evidence for the inter-and intracontinental dissemination of avian influenza viruses via migration flyways. PLoS One. 2019 Jun 26;14(6):e0218506..  Abstract  
submitted by kickingbird at Jun, 28, 2019 from PLoS One. 2019 Jun 26;14(6):e0218506. (via https://journals.plos.org/plosone/article?id=10.1371/journal)
Genetically related highly pathogenic avian influenza viruses (HPAIVs) of H5N6 subtype caused outbreaks simultaneously in East Asia and Europe-geographically distinct regions-during winter 2017-2018. This ...

Zhuang Q, et al. Diversity and distribution of type A influenza viruses: an updated panorama analysis based on protein sequences. Virol J. 2019 Jun 26;16(1):85.  Abstract  
submitted by kickingbird at Jun, 28, 2019 from Virol J. 2019 Jun 26;16(1):85 (via https://virologyj.biomedcentral.com/articles/10.1186/s12985-)
BACKGROUND: Type A influenza viruses (IAVs) cause significant infections in humans and multiple species of animals including pigs, horses, birds, dogs and some marine animals. They are of complicated phylogenetic ...

Sanz Fadrique R, et al. Guillain-Barré syndrome and influenza vaccines: current evidence. Rev Esp Quimioter. 2019 Jun 20..  Abstract  
submitted by kickingbird at Jun, 25, 2019 from Rev Esp Quimioter. 2019 Jun 20. (via https://www.ncbi.nlm.nih.gov/pubmed/31232571)
OBJECTIVE: Guillain-Barré Syndrome (GBS) as a consequence of influenza vaccination is a relevant topic, yet to be clarified, which raises concern both amongst health care personnel and the general population. ...

Leach S, et al. Requirement for memory B cell activation in protection from heterologous influenza virus reinfection. Int Immunol. 2019 Jun 20..  Abstract  
submitted by kickingbird at Jun, 25, 2019 from Int Immunol. 2019 Jun 20. (via https://academic.oup.com/intimm/advance-article-abstract/doi)
While two memory compartments, memory B cells and long-lived plasma cells, are thought to contribute to the successful establishment of memory recall responses, the unique roles of each cellular compartment ...

Yuan HT, et al. A rare case of influenza A (H3N2)-associated encephalitis with seizure. Am J Emerg Med. 2019 Jun 16..  Abstract  
submitted by kickingbird at Jun, 25, 2019 from Am J Emerg Med. 2019 Jun 16. (via https://www.ajemjournal.com/article/S0735-6757(19)30406-1/fu)
Influenza-associated acute encephalopathy (IAE) is more prevalent in children than in adults and often results in neurological sequelae or even death. Diagnosis of IAE is difficult as clinical presentation ...

Yan HX, Xu HF, He WJ, Xie Y, Dong GY.. Phylogenetic analysis of HA and NA genes of influenza H1N1 viruses from 1918 to 2017. Acta Virol. 2019;63(2):195-202..  Abstract  
submitted by kickingbird at Jun, 25, 2019 from Acta Virol. 2019;63(2):195-202. (via https://www.ncbi.nlm.nih.gov/pubmed/31230448)
The 1918 "Spanish" pandemic is the earliest known influenza H1N1 virus. Since then H1N1 viruses circulated between humans and animals continuously. With the increased amount of samples of H1N1 viruses ...

Ma MJ, et al. Characterization of antibody and memory T cell response in H7N9 survivors: A cross-sectional analysis. Clin Microbiol Infect. 2019 Jun 20.  Abstract  
submitted by kickingbird at Jun, 25, 2019 from Clin Microbiol Infect. 2019 Jun 20 (via https://www.clinicalmicrobiologyandinfection.com/article/S11)
OBJECTIVES: Despite the importance of immunological memory for protective immunity against viral infection, whether H7N9-specific antibodies and memory T-cell responses remain detectable years after the ...

Adams SE, et al. Effect of influenza H1N1 neuraminidase V116A and I117V mutations on NA activity and sensitivity to NA inhibitors. Antiviral Res. 2019 Jun 19:104539..  Abstract  
submitted by kickingbird at Jun, 24, 2019 from Antiviral Res. 2019 Jun 19:104539. (via https://www.sciencedirect.com/science/article/pii/S016635421)
Neuraminidase inhibitors (NAIs) play a key role in the management of influenza. Given the limited number of FDA-approved anti-influenza drugs, evaluation of potential drug-resistant variants is of high ...

Dane H, et al. Detection of influenza D virus in bovine respiratory disease samples, U.K. Transbound Emerg Dis. 2019 Jun 22.  Abstract  
submitted by kickingbird at Jun, 24, 2019 from Transbound Emerg Dis. 2019 Jun 22 (via https://onlinelibrary.wiley.com/doi/abs/10.1111/tbed.13273)
Influenza D is a newly described virus of cattle, pigs and small ruminants first detected in North America during 2011. Cattle have been shown to be the main viral reservoir and mounting evidence indicates ...

Nemoto M, et al. A single amino acid change in hemagglutinin reduces the cross-reactivity of antiserum against an equine influenza vaccine strain. Arch Virol. 2019 Jun 21..  Abstract  
submitted by kickingbird at Jun, 24, 2019 from Arch Virol. 2019 Jun 21. (via https://link.springer.com/article/10.1007%2Fs00705-019-04328)
Equine influenza virus is an important pathogen for the horse industry because of its economic impact, and vaccination is a key control measure. Our previous work suggested that a mutation at position ...

Prier JE, et al. Early T-BET Expression Ensures an Appropriate CD8+ Lineage-Specific Transcriptional Landscape after Influenza A Virus Infection. J Immunol. 2019 Jun 21..  Abstract  
submitted by kickingbird at Jun, 24, 2019 from J Immunol. 2019 Jun 21. (via https://www.jimmunol.org/content/early/2019/06/21/jimmunol.1)
Virus infection triggers large-scale changes in the phenotype and function of naive CD8+ T cells, resulting in the generation of effector and memory T cells that are then critical for immune clearance. ...

Xiao Y, et al. Deep sequencing of 2009 influenza A/H1N1 virus isolated from volunteer human challenge study participants and natural infections. Virology. 2019 Jun 13;534:96-107..  Abstract  
submitted by kickingbird at Jun, 23, 2019 from Virology. 2019 Jun 13;534:96-107. (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
Nasal wash samples from 15 human volunteers challenged with GMP manufactured influenza A/California/04/2009(H1N1) and from 5 naturally infected influenza patients of the 2009 pandemic were deep sequenced ...

Gianchecchi E, et al. How to assess the effectiveness of nasal influenza vaccines? Role and measurement of sIgA in mucosal secretions. Influenza Other Respir Viruses. 2019 Jun 21..  Abstract  
submitted by kickingbird at Jun, 23, 2019 from Influenza Other Respir Viruses. 2019 Jun 21. (via https://onlinelibrary.wiley.com/doi/full/10.1111/irv.12664)
Secretory IgAs (sIgA) constitute the principal isotype of antibodies present in nasal and mucosal secretions. They are secreted by plasma cells adjacent to the mucosal epithelial cells, the site where ...

Xu X, et al. Update: Influenza Activity in the United States During the 2018-19 Season and Composition of the 2019-20 Influenza Vaccine. MMWR Morb Mortal Wkly Rep. 2019 Jun 21;68(24):544-.  Abstract  
submitted by kickingbird at Jun, 23, 2019 from MMWR Morb Mortal Wkly Rep. 2019 Jun 21;68(24):544- (via https://www.cdc.gov/mmwr/volumes/68/wr/mm6824a3.htm?s_cid=mm)
Influenza activity* in the United States during the 2018-19 season (September 30, 2018-May 18, 2019) was of moderate severity (1). Nationally, influenza-like illness (ILI)? activity began increasing in ...

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