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Prokopyeva E, et al. Experimental Infection Using Mouse-Adapted Influenza B Virus in a Mouse Model. Viruses. 2020 Apr 21;12(4)..  Abstract  
submitted by kickingbird at Apr, 30, 2020 from Viruses. 2020 Apr 21;12(4). (via https://www.ncbi.nlm.nih.gov/pubmed/32326238)
Every year, influenza B viruses (IBVs) contribute to annual illness, and infection can lead to serious respiratory disease among humans. More attention is needed in several areas, such as increasing virulence ...

Lei N, et al. IFITM3 Affects the Level of Antibody Response after Influenza Vaccination. Emerg Microbes Infect. 2020 Apr 23:1-29.  Abstract  
submitted by kickingbird at Apr, 24, 2020 from Emerg Microbes Infect. 2020 Apr 23:1-29 (via https://www.ncbi.nlm.nih.gov/pubmed/32321380)
Interferon-induced transmembrane protein 3 (IFITM3) as an antiviral factor can inhibit replication of several viruses including influenza virus. A single-nucleotide polymorphism rs12252-C of IFITM3 results ...

Lambertz RLO, et al. H2 influenza A virus is not pathogenic in Tmprss2 knock-out mice. Virol J. 2020 Apr 22;17(1):56.  Abstract  
submitted by kickingbird at Apr, 24, 2020 from Virol J. 2020 Apr 22;17(1):56 (via https://www.ncbi.nlm.nih.gov/pubmed/32321537)
The host cell protease TMPRSS2 cleaves the influenza A virus (IAV) hemagglutinin (HA). Several reports have described resistance of Tmprss2-/- knock-out (KO) mice to IAV infection but IAV of the H2 subtype ...

Chen L, Han XD, Li YL, Zhang CX, Xing XQ. Severity and outcomes of influenza-related pneumonia in type A and B strains in China, 2013-2019. Infect Dis Poverty. 2020 Apr 22;9(1):42..  Abstract  
submitted by kickingbird at Apr, 24, 2020 from Infect Dis Poverty. 2020 Apr 22;9(1):42. (via https://www.ncbi.nlm.nih.gov/pubmed/32321576)
BACKGROUND: Inconsistencies exist regarding the severity of illness caused by different influenza strains. The aim of this study was to compare the clinical outcomes of hospitalized adults and adolescents ...

Rahim MMA, et al. Defective influenza A virus RNA products mediate MAVS-dependent upregulation of human leukocyte antigen class I proteins. J Virol. 2020 Apr 22. pii: JVI.00165-20.  Abstract  
submitted by kickingbird at Apr, 24, 2020 from J Virol. 2020 Apr 22. pii: JVI.00165-20 (via https://www.ncbi.nlm.nih.gov/pubmed/32321802)
Influenza A virus (IAV) increases presentation of class I human leukocyte antigen (HLA) proteins that limit antiviral responses mediated by natural killer (NK) cells, but molecular mechanisms have not ...

Verhagen JH, et al. Phylogeography and antigenic diversity of low pathogenic avian influenza H13 and H16 viruses. J Virol. 2020 Apr 22. pii: JVI.00537-20..  Abstract  
submitted by kickingbird at Apr, 24, 2020 from J Virol. 2020 Apr 22. pii: JVI.00537-20. (via https://www.ncbi.nlm.nih.gov/pubmed/32321814)
Low pathogenic avian influenza viruses (LPAIVs) are genetically highly variable and have diversified into multiple evolutionary lineages that are primarily associated with wild bird reservoirs. Antigenic ...

Kim HO, et al. Host Cell Mimic Polymersomes for Rapid Detection of Highly Pathogenic Influenza Virus via a Viral Fusion and Cell Entry Mechanism. Adv Funct Mater. 2018 Aug 22;28(34):1800960.  Abstract  
submitted by kickingbird at Apr, 23, 2020 from Adv Funct Mater. 2018 Aug 22;28(34):1800960 (via https://www.ncbi.nlm.nih.gov/pubmed/32313543)
Highly pathogenic avian influenza virus (HPAIV) infections have occurred continuously and crossed the species barrier to humans, leading to fatalities. A polymerase chain reaction based molecular test ...

Shittu I, et al. First detection of highly pathogenic H5N6 avian influenza virus on the African continent. Emerg Microbes Infect. 2020 Apr 20:1-14..  Abstract  
submitted by kickingbird at Apr, 23, 2020 from Emerg Microbes Infect. 2020 Apr 20:1-14. (via https://www.ncbi.nlm.nih.gov/pubmed/32312185)
Since 2013, highly pathogenic avian influenza (HPAI) subtype H5N6 (clade 2.3.4.4) has been reported in wild birds and poultry in Asia as well as in other parts of the globe. In Africa, information on the ...

Whitman J, Jayaprakash C. Stochastic modeling of influenza spread dynamics with recurrences. PLoS One. 2020 Apr 21;15(4):e0231521.  Abstract  
submitted by kickingbird at Apr, 23, 2020 from PLoS One. 2020 Apr 21;15(4):e0231521 (via https://www.ncbi.nlm.nih.gov/pubmed/32315318)
We present results of a study of a simple, stochastic, agent-based model of influenza A infection, simulating its dynamics over the course of one flu season. Building on an early work of Bartlett, we define ...

Zachreson C, Fair KM, Harding N, Prokopenko M. Interfering with influenza: nonlinear coupling of reactive and static mitigation strategies. J R Soc Interface. 2020 Apr;17(165):20190728..  Abstract  
submitted by kickingbird at Apr, 23, 2020 from J R Soc Interface. 2020 Apr;17(165):20190728. (via https://www.ncbi.nlm.nih.gov/pubmed/32316882)
When new, highly infectious strains of influenza emerge, global pandemics can occur before an effective vaccine is developed. Without a strain-specific vaccine, pandemics can only be mitigated by employing ...

Cowling BJ, et al. Impact assessment of non-pharmaceutical interventions against coronavirus disease 2019 and influenza in Hong Kong: an observational study. Lancet Public Health. 2020 Apr 17..  Abstract  
submitted by kickingbird at Apr, 23, 2020 from Lancet Public Health. 2020 Apr 17. (via https://www.ncbi.nlm.nih.gov/pubmed/32311320)
BACKGROUND: A range of public health measures have been implemented to suppress local transmission of coronavirus disease 2019 (COVID-19) in Hong Kong. We examined the effect of these interventions and ...

Wu J, et al. Disulfide isomerase ERp57 improves the stability and immunogenicity of H3N2 influenza virus hemagglutinin. Virol J. 2020 Apr 21;17(1):55..  Abstract  
submitted by kickingbird at Apr, 23, 2020 from Virol J. 2020 Apr 21;17(1):55. (via https://www.ncbi.nlm.nih.gov/pubmed/32316996)
BACKGROUND: Hemagglutinin (HA), as the surface immunogenic protein, is the most important component of influenza viruses. Previous studies showed that the stability of HA was significant for HA's immunogenicity, ...

Nakakita SI, et al. Preparation and Detection of Glycan-Binding Activity of Influenza Virus. Methods Mol Biol. 2020;2132:567-583..  Abstract  
submitted by kickingbird at Apr, 21, 2020 from Methods Mol Biol. 2020;2132:567-583. (via https://www.ncbi.nlm.nih.gov/pubmed/32306357)
We describe a method to detect influenza virus using an evanescent-field-activated fluorescence scanner type glycan array and ELISA system. Neoglycoprotein was prepared by combination of organic chemistry ...

Dudalski N, et al. Experimental Investigation of Far Field Human Cough Airflows from Healthy and: Influenza-Infected Subjects. Indoor Air. 2020 Apr 18.  Abstract  
submitted by kickingbird at Apr, 21, 2020 from Indoor Air. 2020 Apr 18 (via https://www.ncbi.nlm.nih.gov/pubmed/32304605)
Seasonal influenza epidemics have been responsible for causing increased economic expenditures and many deaths worldwide. Evidence exists to support the claim that the virus can be spread through the air, ...

Liu Q, et al. Global gene expression analysis data of chicken dendritic cells infected with H9N2 avian influenza virus. Data Brief. 2020 Mar 16;30:105430.  Abstract  
submitted by kickingbird at Apr, 20, 2020 from Data Brief. 2020 Mar 16;30:105430 (via https://www.ncbi.nlm.nih.gov/pubmed/32300615)
This data article reports the global gene expression analysis data of chicken DCs infected with H9N2 avian influenza virus (AIV) compared with mock infection. The differentially expressed genes (DEGs), ...

Wang Q, et al. Long-term clinical prognosis of human infections with avian influenza A(H7N9) viruses in China after hospitalization. EClinicalMedicine. 2020 Feb 19;20:100282..  Abstract  
submitted by kickingbird at Apr, 20, 2020 from EClinicalMedicine. 2020 Feb 19;20:100282. (via https://www.ncbi.nlm.nih.gov/pubmed/32300739)
Background: Mainland China has experienced five epidemics of human cases of avian influenza A(H7N9) virus infection since 2013. We conducted a prospective study to assess long-term clinical, pulmonary ...

Dos Santos Bezerra R, et al. Detection of Influenza A(H3N2) Virus RNA in Donated Blood. Emerg Infect Dis. 2020 Apr 18;26(7)..  Abstract  
submitted by kickingbird at Apr, 20, 2020 from Emerg Infect Dis. 2020 Apr 18;26(7). (via https://www.ncbi.nlm.nih.gov/pubmed/32304372)
Influenza A virus infection has rarely been documented to cause viremia. In 28 blood donations in Brazil that were deferred because of postdonation information, we identified influenza A(H3N2) virus RNA ...

Wandzik JM, et al. A Structure-Based Model for the Complete Transcription Cycle of Influenza Polymerase. Cell. 2020 Apr 16..  Abstract  
submitted by kickingbird at Apr, 20, 2020 from Cell. 2020 Apr 16. (via https://www.ncbi.nlm.nih.gov/pubmed/32304664)
Influenza polymerase uses unique mechanisms to synthesize capped and polyadenylated mRNAs from the genomic viral RNA (vRNA) template, which is packaged inside ribonucleoprotein particles (vRNPs). Here, ...

Thompson AJ, et al. Human Influenza Virus Hemagglutinins Contain Conserved Oligomannose N-Linked Glycans Allowing Potent Neutralization by Lectins. Cell Host Microbe. 2020 Apr 10.  Abstract  
submitted by kickingbird at Apr, 18, 2020 from Cell Host Microbe. 2020 Apr 10 (via https://www.ncbi.nlm.nih.gov/pubmed/32298658)
Hemagglutinins (HAs) from human influenza viruses adapt to bind α2-6-linked sialosides, overcoming a receptor-defined species barrier distinct from the α2-3 specificity of avian virus progenitors. Additionally, ...

Walker AP, Sharps J, Fodor E. Mutation of an influenza virus polymerase 3´ RNA promoter binding site inhibits transcription elongation. J Virol. 2020 Apr 15. pii: JVI.00498-20..  Abstract  
submitted by kickingbird at Apr, 18, 2020 from J Virol. 2020 Apr 15. pii: JVI.00498-20. (via https://jvi.asm.org/content/early/2020/04/09/JVI.00498-20)
Influenza A virus encodes a viral RNA-dependent RNA polymerase (FluPolA), which is responsible for transcribing and replicating the negative-sense viral RNA (vRNA) genome. FluPolA transcribes vRNA using ...

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