Dreier C, et al. Mutations in the H7 HA and PB1 genes of avian influenza a viruses increase viral pathogenicity and contact transmission in guinea pigs. Emerg Microbes Infect. 2019;8(1):1324-1336.. Abstract
submitted by kickingbird at Sep, 12, 2019 from Emerg Microbes Infect. 2019;8(1):1324-1336. (via https://www.tandfonline.com/doi/full/10.1080/22221751.2019.1)
Avian influenza A viruses (AIV) of the H7 subtype continue to evolve posing a pandemic threat. However, molecular markers of H7N7 AIV pathogenicity and transmission in mammals remain poorly understood. ... Acosta E, et al. Determinants of Influenza Mortality Trends: Age-Period-Cohort Analysis of Influenza Mortality in the United States, 1959-2016. Demography. 2019 Sep 9. Abstract
submitted by kickingbird at Sep, 12, 2019 from Demography. 2019 Sep 9 (via https://link.springer.com/article/10.1007%2Fs13524-019-00809)
This study examines the roles of age, period, and cohort in influenza mortality trends over the years 1959-2016 in the United States. First, we use Serfling models based on Lexis surfaces to highlight ... Nakamura K, et al. Systematic evaluation of suspension MDCK cells, adherent MDCK cells, and LLC-MK2 cells for preparing influenza vaccine seed virus. Vaccine. 2019 Sep 6.. Abstract
submitted by kickingbird at Sep, 12, 2019 from Vaccine. 2019 Sep 6. (via https://www.sciencedirect.com/science/article/pii/S0264410X1)
Suspension Madin-Darby canine kidney (MDCK) cells (MDCK-N), adherent MDCK cells (MDCK-C), and adherent rhesus monkey kidney LLC-MK2 cells (LLC-MK2D) were systematically evaluated for the preparation of ... Zhang S, et al. Influenza A virus infection induces liver injury in mice. Microb Pathog.2019 Sep 7:103736.. Abstract
submitted by kickingbird at Sep, 12, 2019 from Microb Pathog.2019 Sep 7:103736. (via https://www.sciencedirect.com/science/article/pii/S088240101)
Respiratory infections such as SARS-CoV in humans are often accompanied by mild and self-limiting hepatitis. As a respiratory disease, influenza A virus (IAV) infection can lead to hepatitis, but the mechanism ... Guan L, et al. H3N2 avian influenza viruses detected in live poultry markets in China bind to human-type receptors and transmit in guinea pigs and ferrets. Emerg Microbes Infect. 2019;8(1):1280-1290. Abstract
submitted by kickingbird at Sep, 11, 2019 from Emerg Microbes Infect. 2019;8(1):1280-1290 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2019.1)
The H3N2 influenza viruses became widespread in humans during the 1968 H3N2 pandemic and have been a major cause of influenza epidemics ever since. Different lineages of H3N2 influenza viruses are also ... Liu R, et al. Genetic and antigenic characteristics of a human influenza C virus clinical isolate. J Med Virol. 2019 Sep 9. Abstract
submitted by kickingbird at Sep, 11, 2019 from J Med Virol. 2019 Sep 9 (via https://onlinelibrary.wiley.com/doi/abs/10.1002/jmv.25589)
Unlike influenza A and B viruses that infect humans and cause severe diseases in seasonal epidemics, influenza C virus (ICV) is a ubiquitous childhood pathogen typically causing mild respiratory symptoms. ... Li J, et al. Delayed peak of human infections and ongoing reassortment of H7N9 avian influenza virus in the newly affected western Chineses provinces during Wave Five. Int J Infect Dis. 2019 Sep 6.. Abstract
submitted by kickingbird at Sep, 11, 2019 from Int J Infect Dis. 2019 Sep 6. (via https://www.ijidonline.com/article/S1201-9712(19)30363-7/pdf)
OBJECTIVES: Eight additional provinces in western China reported human infections for the first time during the fifth wave of human H7N9 infections. Our study aimed to analyze the epidemiological and virological ... Zhang H, et al. Novel influenza polymerase PB2 inhibitors for the treatment of influenza A infection. Bioorg Med Chem Lett. 2019 Aug 24:126639.. Abstract
submitted by kickingbird at Sep, 10, 2019 from Bioorg Med Chem Lett. 2019 Aug 24:126639. (via https://www.sciencedirect.com/science/article/pii/S0960894X1)
Exploration of the chemical space of known influenza polymerase PB2 inhibitor Pimodivir, was performed by our group. We synthesized and identified compounds 16a and 16b, two novel thienopyrimidine derivatives ... Olguin-Perglione C, et al. Multifocal outbreak of equine influenza in vaccinated horses in Argentina in 2018: Epidemiological aspects and molecular characterisation of the involved virus strains. Equine Vet J. 2019 Sep 8.. Abstract
submitted by kickingbird at Sep, 10, 2019 from Equine Vet J. 2019 Sep 8. (via https://onlinelibrary.wiley.com/doi/abs/10.1111/evj.13176)
BACKGROUND: Equine influenza is an important cause of respiratory disease of horses worldwide. The equine influenza virus (EIV) undergoes antigenic drift through the accumulation of amino acid substitutions ... Leyson C, et al. Pathogenicity and genomic changes of a 2016 European H5N8 highly pathogenic avian influenza virus (clade 2.3.4.4) in experimentally infected mallards and chickens. Virology. 2019 Aug 22;537:172-185. Abstract
submitted by kickingbird at Sep, 9, 2019 from Virology. 2019 Aug 22;537:172-185 (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
Highly pathogenic avian influenza H5N8 clade 2.3.4.4 virus caused outbreaks in poultry and unusually high mortality in wild birds in 2016-2017. The pathobiology of one of these viruses was examined in ... Zhang S, et al. p-STAT1 regulates the influenza A virus replication and inflammatory response in vitro and vivo. Virology. 2019 Aug 25;537:110-120. Abstract
submitted by kickingbird at Sep, 9, 2019 from Virology. 2019 Aug 25;537:110-120 (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
nfluenza A virus infection activates various intracellular signaling pathways, which is mediated by the transcription factors. Here, a quantitative phosphoproteomic analysis of A549?cells after infection ... Adlhoch C, et al. Estimation of the number of exposed people during highly pathogenic avian influenza virus outbreaks in EU/EEA countries, October 2016-September 2018. Zoonoses Public Health. 2019 Sep 6.. Abstract
submitted by kickingbird at Sep, 9, 2019 from Zoonoses Public Health. 2019 Sep 6. (via https://onlinelibrary.wiley.com/doi/full/10.1111/zph.12629)
We estimated that more than 11,000 people were exposed to highly pathogenic avian influenza viruses in EU/EEA countries over the outbreak period October 2016-September 2018 by cross-linking data submitted ... Jané M, et al. Epidemiological and clinical characteristics of children hospitalized due to influenza A and B in the south of Europe, 2010-2016. Sci Rep. 2019 Sep 6;9(1):12853.. Abstract
submitted by kickingbird at Sep, 9, 2019 from Sci Rep. 2019 Sep 6;9(1):12853. (via https://www.nature.com/articles/s41598-019-49273-z)
Influenza produces annual epidemics that affect 5-15% of the world population. Complications and hospitalizations are more frequent in childhood. This study describes and analyses the epidemiological and ... Jansen JM, et al. Influenza virus-specific CD4+ and CD8+ T cell-mediated immunity induced by infection and vaccination. J Clin Virol. 2019 Aug 24;119:44-52. Abstract
submitted by kickingbird at Sep, 9, 2019 from J Clin Virol. 2019 Aug 24;119:44-52 (via https://www.ncbi.nlm.nih.gov/pubmed/31491709)
Influenza A and B virus infections are a major cause of respiratory disease in humans and are responsible for substantial morbidity and mortality worldwide. Vaccination against influenza mainly aims at ... Palekar RS, et al. Burden of influenza-associated respiratory hospitalizations in the Americas, 2010-2015. PLoS One. 2019 Sep 6;14(9):e0221479.. Abstract
submitted by kickingbird at Sep, 9, 2019 from PLoS One. 2019 Sep 6;14(9):e0221479. (via https://journals.plos.org/plosone/article?id=10.1371/journal)
BACKGROUND: Despite having influenza vaccination policies and programs, countries in the Americas underutilize seasonal influenza vaccine, in part because of insufficient evidence about severe influenza ... Zhang T, et al. First Detection of a Novel Reassortant Avian Influenza A(H5N6) Clade 2.3.2.1c Virus, Isolated from a Wild Bird in China. Microbiol Resour Announc. 2019 Sep 5;8(36). Abstract
submitted by kickingbird at Sep, 9, 2019 from Microbiol Resour Announc. 2019 Sep 5;8(36) (via https://mra.asm.org/content/8/36/e00797-19)
We report the first isolation of a reassortant clade 2.3.2.1c avian influenza A(H5N6) virus isolated from a wild bird sample in Jiangxi, China, in 2016. Sequence analyses indicated that this virus most ... Zak AJ, Hill BD, Rizvi SM, Smith MR, Yang M, Wen F. Enhancing the Yield and Quality of Influenza Virus-like Particles (VLPs) Produced in Insect Cells by Inhibiting Cytopathic Effects of Matrix Protein M2. ACS Synth Biol. 2019 Sep 5.. Abstract
submitted by kickingbird at Sep, 9, 2019 from ACS Synth Biol. 2019 Sep 5. (via https://pubs.acs.org/doi/10.1021/acssynbio.9b00111)
To provide broader protection and eliminate the need for annual update of influenza vaccines, biomolecular engineering of influenza virus-like particles (VLPs) to display more conserved influenza proteins ... Fan H, et al. Structures of influenza A virus RNA polymerase offer insight into viral genome replication. Nature. 2019 Sep 4.. Abstract
submitted by kickingbird at Sep, 9, 2019 from Nature. 2019 Sep 4. (via https://www.nature.com/articles/s41586-019-1530-7)
Influenza A viruses are responsible for seasonal epidemics, and pandemics can arise from the transmission of novel zoonotic influenza A viruses to humans1,2. Influenza A viruses contain a segmented negative-sense ... Li J, et al. Amino acid substitutions in antigenic region B of hemagglutinin play a critical role in the antigenic drift of subclade 2.3.4.4 highly pathogenic H5NX influenza viruses. Transbound Emerg Dis. 2019 Sep 4.. Abstract
submitted by kickingbird at Sep, 9, 2019 from Transbound Emerg Dis. 2019 Sep 4. (via https://onlinelibrary.wiley.com/doi/abs/10.1111/tbed.13347)
As one of the important control strategies for highly pathogenic avian influenza (HPAI) in China, vaccination has been implemented compulsively in poultry flocks since 2004. However, the emergence and ... Umberto M, et al. Avian Influenza H5N8 Outbreak in African Penguins (Spheniscus demersus), Namibia, 2019. J Wildl Dis. 2019 Sep 4. Abstract
submitted by kickingbird at Sep, 9, 2019 from J Wildl Dis. 2019 Sep 4 (via https://www.ncbi.nlm.nih.gov/pubmed/31483707)
In January 2019, high mortalities were reported among African Penguins (Spheniscus demersus) in a breeding colony on Halifax Island, Namibia, Africa. Analysis of samples by reverse transcription quantitative ... 7583 items, 20/Page, Page[143/380][|<<] [|<] [141] [142] [143] [144] [145] [146] [147] [148] [149] [150] [>|] [>>|] |
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