Mohan T, Nguyen HT, Kniss K, Mishin VP, Merced-Mor. Cluster of Oseltamivir-Resistant and Hemagglutinin Antigenically Drifted Influenza A(H1N1)pdm09 Viruses, Texas, USA, January 2020. Emerg Infect Dis. 2021 Jul;27(7):1953-1957. Abstract submitted by kickingbird at Jun, 22, 2021 from Emerg Infect Dis. 2021 Jul;27(7):1953-1957 (via https://wwwnc.cdc.gov/eid/article/27/7/20-4593_article) Four cases of oseltamivir-resistant influenza A(H1N1)pdm09 virus infection were detected among inhabitants of a border detention center in Texas, USA. Hemagglutinin of these viruses belongs to 6B.1A5A-156K ... Pedruzzi G, Rouzine IM. An evolution-based high-fidelity method of epistasis measurement: Theory and application to influenza. PLoS Pathog. 2021 Jun 21;17(6):e1009669. Abstract submitted by kickingbird at Jun, 22, 2021 from PLoS Pathog. 2021 Jun 21;17(6):e1009669 (via https://journals.plos.org/plospathogens/article?id=10.1371/j) Linkage effects in a multi-locus population strongly influence its evolution. The models based on the traveling wave approach enable us to predict the average speed of evolution and the statistics of phylogeny. ... Miyauchi K, Adachi Y, Tonouchi K, Yajima T, Harada. Influenza virus infection expands the breadth of antibody responses through IL-4 signalling in B cells. Nat Commun. 2021 Jun 18;12(1):3789. Abstract submitted by kickingbird at Jun, 20, 2021 from Nat Commun. 2021 Jun 18;12(1):3789 (via https://www.nature.com/articles/s41467-021-24090-z) Influenza viruses are a major public health problem. Vaccines are the best available countermeasure to induce effective immunity against infection with seasonal influenza viruses; however, the breadth ... Sun H, Liu J, Xiao Y, Duan Y, Yang J, Chen Y, Yu Y. Pathogenicity of novel reassortant Eurasian avian-like H1N1 influenza virus in pigs. Virology. 2021 Jun 6;561:28-35. Abstract submitted by kickingbird at Jun, 19, 2021 from Virology. 2021 Jun 6;561:28-35 (via https://www.sciencedirect.com/science/article/abs/pii/S00426) Reassortant Eurasian avian-like (EA) H1N1 virus, possessing 2009 pandemic (pdm/09) and triple-reassortant (TR)-derived internal genes, namely G4 genotype, has replaced the G1 genotype EA H1N1 virus (all ... Pyankova OG, Susloparov IM, Moiseeva AA, Kolosova. Isolation of clade 2.3.4.4b A(H5N8), a highly pathogenic avian influenza virus, from a worker during an outbreak on a poultry farm, Russia, December 2020. Euro Surveill. 2021 Jun;26(24). Abstract submitted by kickingbird at Jun, 19, 2021 from Euro Surveill. 2021 Jun;26(24) (via https://www.eurosurveillance.org/content/10.2807/1560-7917.E) This study presents the isolation of influenza A(H5N8) virus clade 2.3.4.4b from a poultry worker during an outbreak of highly pathogenic avian influenza A(H5N8) among chickens at a poultry farm in Astrakhan, ... Yadav M, Igarashi M, Yamamoto N. Dynamic residue interaction network analysis of the oseltamivir binding site of N1 neuraminidase and its H274Y mutation site conferring drug resistance in influenza A virus. PeerJ. 2021 Jun 2;9:e11552. Abstract submitted by kickingbird at Jun, 19, 2021 from PeerJ. 2021 Jun 2;9:e11552 (via https://peerj.com/articles/11552/) Background: Oseltamivir (OTV)-resistant influenza virus exhibits His-to-Tyr mutation at residue 274 (H274Y) in N1 neuraminidase (NA). However, the molecular mechanisms by which the H274Y mutation in NA ... Zhang J, Li X, Wang X, Ye H, Li B, Chen Y, Chen J,. Genomic evolution, transmission dynamics, and pathogenicity of avian influenza A (H5N8) viruses emerging in China, 2020. Virus Evol. 2021 May 6;7(1):veab046. Abstract submitted by kickingbird at Jun, 19, 2021 from Virus Evol. 2021 May 6;7(1):veab046 (via https://academic.oup.com/ve/article/7/1/veab046/6270935) Multiple recent outbreaks of highly pathogenic H5N8 viruses originating in aquatic birds frequently occurred in most European countries, Russia, South Korea, and Japan during the winter of 2020-21, and ... Kavian N, Hachim A, Cowling BJ, Valkenburg SA. Repeated influenza vaccination provides cumulative protection from distinct H3N2 viruses. Clin Transl Immunology. 2021 Jun 13;10(6):e1297. Abstract submitted by kickingbird at Jun, 18, 2021 from Clin Transl Immunology. 2021 Jun 13;10(6):e1297 (via https://onlinelibrary.wiley.com/doi/10.1002/cti2.1297) Objectives: Current inactivated influenza vaccines provide suboptimal protection against antigenic drift, and repeated annual vaccinations shape antibody specificity but the effect on protection from infection ... Yu Y, Wu M, Cui X, Xu F, Wen F, Pan L, Li S, Sun H. Pathogenicity and transmissibility of current H3N2 swine influenza virus in Southern China: A zoonotic potential. Transbound Emerg Dis. 2021 Jun 15. Abstract submitted by kickingbird at Jun, 17, 2021 from Transbound Emerg Dis. 2021 Jun 15 (via https://onlinelibrary.wiley.com/doi/10.1111/tbed.14190) Swine are considered as "mixing vessels" of influenza A viruses and play an important role in the generation of novel influenza pandemics. In this study, we described that the H3N2 swine influenza (swH3N2) ... Blumenkrantz DR, Mehoke T, Shaw-Saliba K, Powell H. Identification of H3N2 NA and PB1-F2 genetic variants and their association with disease symptoms during the 2014-15 influenza season. Virus Evol. 2021 Jun 4;7(1):veab047. Abstract submitted by kickingbird at Jun, 17, 2021 from Virus Evol. 2021 Jun 4;7(1):veab047 (via https://academic.oup.com/ve/article/7/1/veab047/6272594) The 2014-15 influenza season saw the emergence of an H3N2 antigenic drift variant that formed the 3C.2a HA clade. Whole viral genomes were sequenced from nasopharyngeal swabs of ninety-four patients with ... Ghabeshi S, Ebrahimie E, Yavarian J, Salimi V, Sha. Molecular characterization of low pathogenic avian influenza H9N2 virus during co-circulation with newly-emerged highly pathogenic avian influenza H5N8 virus in Iran. Acta Virol. 2021;65(2):200-211. Abstract submitted by kickingbird at Jun, 17, 2021 from Acta Virol. 2021;65(2):200-211 (via https://pubmed.ncbi.nlm.nih.gov/34130471/) Identification of molecular characteristics of low pathogenic avian influenza (LPAI) H9N2 virus provides insights into the evolution of this subtype due to the modulation of genomic characteristics in ... Guthmiller JJ, Utset HA, Henry C, Li L, Zheng NY,. An Egg-Derived Sulfated N-Acetyllactosamine Glycan Is an Antigenic Decoy of Influenza Virus Vaccines. mBio. 2021 Jun 15:e0083821. Abstract submitted by kickingbird at Jun, 16, 2021 from mBio. 2021 Jun 15:e0083821 (via https://journals.asm.org/doi/10.1128/mBio.00838-21) Influenza viruses grown in eggs for the purposes of vaccine generation often acquire mutations during egg adaptation or possess different glycosylation patterns than viruses circulating among humans. Here, ... Kwon JH, Lee DH, Criado MF, Killmaster L, Ali MZ,. Genetic evolution and transmission dynamics of clade 2.3.2.1a highly pathogenic avian influenza A/H5N1 viruses in Bangladesh. Virus Evol. 2020 Jun 13;6(2):veaa046. Abstract submitted by kickingbird at Jun, 16, 2021 from Virus Evol. 2020 Jun 13;6(2):veaa046 (via https://academic.oup.com/ve/article/6/2/veaa046/5857140) Asian lineage A/H5N1 highly pathogenic avian influenza viruses (HPAIVs) have been responsible for continuous outbreaks in Bangladesh since 2007. Although clades 2.2.2 and 2.3.4.2 HPAIVs have disappeared ... Zhao T, Asawa K, Masuda T, Honda A, Kushiro K, Cab. Fluorescent polymeric nanoparticle for ratiometric temperature sensing allows real-time monitoring in influenza virus-infected cells. J Colloid Interface Sci. 2021 Jun 1;601:825-832. Abstract submitted by kickingbird at Jun, 15, 2021 from J Colloid Interface Sci. 2021 Jun 1;601:825-832 (via https://www.sciencedirect.com/science/article/abs/pii/S00219) Temperature is a key indicator of infection and disease, however, it is difficult to measure at a cellular level. Nanoparticles are applied to measure the cellular temperature, and enhancement of the stability ... Madslien K, Moldal T, Gjerset B, Gudmundsson S, Fo. First detection of highly pathogenic avian influenza virus in Norway. BMC Vet Res. 2021 Jun 12;17(1):218. Abstract submitted by kickingbird at Jun, 15, 2021 from BMC Vet Res. 2021 Jun 12;17(1):218 (via https://bmcvetres.biomedcentral.com/articles/10.1186/s12917-) Background: Several outbreaks of highly pathogenic avian influenza (HPAI) caused by influenza A virus of subtype H5N8 have been reported in wild birds and poultry in Europe during autumn 2020. Norway is ... Song W, Guo J, Ni X, Wu J, Xia W, He F, Wang X, Fa. Changes of avian influenza virus subtypes before and after vaccination in live poultry in Nanchang, China from 2016 to 2019. Microbes Infect. 2021 Jun 8:104848. Abstract submitted by kickingbird at Jun, 15, 2021 from Microbes Infect. 2021 Jun 8:104848 (via https://www.sciencedirect.com/science/article/pii/S128645792) We investigated fluctuations in the detection rates of avian influenza virus (AIV) subtypes H5, H7, and H9 in live bird markets (LBMs) in Nanchang city, Chinese province Jiangxi, before and after the Chinese ... Schroff P, Hovey JR, Tharumia Jagadeesan C, Nagala. Cardiac Tamponade Secondary to Influenza B Infection. Cureus. 2021 May 7;13(5):e14888. Abstract submitted by kickingbird at Jun, 12, 2021 from Cureus. 2021 May 7;13(5):e14888 (via https://www.cureus.com/articles/58416-cardiac-tamponade-seco) Every year, Influenza infection contributes to significant morbidity and mortality carrying a huge economic burden. Extra-pulmonary manifestations are increasingly being recognized. We present a 29-year-old ... Ferrara F, Del Rosario JMM, da Costa KAS, Kinsley. Development of Lentiviral Vectors Pseudotyped With Influenza B Hemagglutinins: Application in Vaccine Immunogenicity, mAb Potency, and Sero-Surveillance Studies. Front Immunol. 2021 May 24;12:661379. Abstract submitted by kickingbird at Jun, 12, 2021 from Front Immunol. 2021 May 24;12:661379 (via https://www.frontiersin.org/articles/10.3389/fimmu.2021.6613) Influenza B viruses (IBV) cause respiratory disease epidemics in humans and are therefore components of seasonal influenza vaccines. Serological methods are employed to evaluate vaccine immunogenicity ... Xing L, Chen Y, Chen B, Bu L, Liu Y, Zeng Z, Guan. Antigenic Drift of the Hemagglutinin from an Influenza A (H1N1) pdm09 Clinical Isolate Increases its Pathogenicity In Vitro. Virol Sin. 2021 Jun 9:1–8. doi: 10.1007/s12250-021. Abstract submitted by kickingbird at Jun, 12, 2021 from Virol Sin. 2021 Jun 9:1–8. doi: 10.1007/s12250-021 (via https://link.springer.com/article/10.1007/s12250-021-00401-y) The influenza A (H1N1) pdm09 virus emerged in 2009 and has been continuously circulating in humans for over ten years. Here, we analyzed a clinical influenza A (H1N1) pdm09-infected patient case hospitalized ... Liu S, Mok BW, Deng S, Liu H, Wang P, Song W, Chen. Mammalian cells use the autophagy process to restrict avian influenza virus replication. Cell Rep. 2021 Jun 8;35(10):109213. Abstract submitted by kickingbird at Jun, 12, 2021 from Cell Rep. 2021 Jun 8;35(10):109213 (via https://www.cell.com/cell-reports/fulltext/S2211-1247(21)005) Host adaptive mutations in the influenza A virus (IAV) PB2 protein are critical for human infection, but their molecular action is not well understood. 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