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2024-7-17 23:10:46
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Russell CJ. Hemagglutinin Stability and Its Impact on Influenza A Virus Infectivity, Pathogenicity, and Transmissibility in Avians, Mice, Swine, Seals, Ferrets, and Humans. Viruses. 2021 Apr 24;13(5):746.  Abstract  
submitted by kickingbird at May, 3, 2021 from Viruses. 2021 Apr 24;13(5):746 (via https://www.mdpi.com/1999-4915/13/5/746)
Genetically diverse influenza A viruses (IAVs) circulate in wild aquatic birds. From this reservoir, IAVs sporadically cause outbreaks, epidemics, and pandemics in wild and domestic avians, wild land and ...

Pando R, Stern S, Nemet I, Glatman-Freedman A, Sef. Diversity in the Circulation of Influenza A(H3N2) Viruses in the Northern Hemisphere in the 2018-19 Season. Vaccines (Basel). 2021 Apr 13;9(4):375.  Abstract  
submitted by kickingbird at May, 1, 2021 from Vaccines (Basel). 2021 Apr 13;9(4):375 (via https://www.mdpi.com/2076-393X/9/4/375)
While vaccination is considered the most effective means to prevent influenza infection, its seasonal effectiveness varies, depending on the circulating influenza strains. Here, we characterized the circulation ...

An M, Vitale J, Han K, Ng´ombe JN, Ji I.. Effects of Spatial Characteristics on the Spread of the Highly Pathogenic Avian Influenza (HPAI) in Korea. Int J Environ Res Public Health. 2021 Apr 13;18(8).  Abstract  
submitted by kickingbird at May, 1, 2021 from Int J Environ Res Public Health. 2021 Apr 13;18(8) (via https://www.mdpi.com/1660-4601/18/8/4081)
This paper examines the effects of regional characteristics on the spread of the highly pathogenic avian influenza (HPAI) during Korea's 2016-2017 outbreak. A spatial econometric model is used to determine ...

Weis S, Te Velthuis AJW.. Influenza Virus RNA Synthesis and the Innate Immune Response. Viruses. 2021 Apr 28;13(5):780.  Abstract  
submitted by kickingbird at May, 1, 2021 from Viruses. 2021 Apr 28;13(5):780 (via https://www.mdpi.com/1999-4915/13/5/780)
Infection with influenza A and B viruses results in a mild to severe respiratory tract infection. It is widely accepted that many factors affect the severity of influenza disease, including viral replication, ...

Lai Y, Han T, Zhan S, Jiang Y, Liu X, Li G. Antiviral Activity of Isoimperatorin Against Influenza A Virus in vitro and its Inhibition of Neuraminidase. Front Pharmacol. 2021 Apr 13;12:657826..  Abstract  
submitted by kickingbird at May, 1, 2021 from Front Pharmacol. 2021 Apr 13;12:657826. (via https://www.frontiersin.org/articles/10.3389/fphar.2021.6578)
Influenza A virus (IAV) poses a severe threat to human health and is a major public health problem worldwide. As global anti-influenza virus drug resistance has increased significantly, there is an urgent ...

Kwon JH, Criado MF, Killmaster L, Ali MZ, Giasuddi. Efficacy of two vaccines against recent emergent antigenic variants of clade 2.3.2.1a highly pathogenic avian influenza viruses in Bangladesh. Vaccine. 2021 Apr 25:S0264-410X(21)00459-X..  Abstract  
submitted by kickingbird at Apr, 30, 2021 from Vaccine. 2021 Apr 25:S0264-410X(21)00459-X. (via https://www.sciencedirect.com/science/article/pii/S0264410X2)
H5N1 highly pathogenic avian influenza viruses (HPAIVs) have caused outbreaks in poultry in Bangladesh since 2007. While clade 2.2.2 and 2.3.4.2 HPAIVs have not been detected since 2012, clade 2.3.2.1a ...

Danilenko AV, Kolosova NP, Shvalov AN, Ilyicheva T. Evaluation of HA-D222G/N polymorphism using targeted NGS analysis in A(H1N1)pdm09 influenza virus in Russia in 2018-2019. PLoS One. 2021 Apr 29;16(4):e0251019.  Abstract  
submitted by kickingbird at Apr, 30, 2021 from PLoS One. 2021 Apr 29;16(4):e0251019 (via https://journals.plos.org/plosone/article?id=10.1371/journal)
Outbreaks of influenza, which is a contagious respiratory disease, occur throughout the world annually, affecting millions of people with many fatal cases. The D222G/N mutations in the hemagglutinin (HA) ...

Yin X, Deng G, Zeng X, Cui P, Hou Y, Liu Y, Fang J. Genetic and biological properties of H7N9 avian influenza viruses detected after application of the H7N9 poultry vaccine in China. PLoS Pathog. 2021 Apr 27;17(4):e1009561.  Abstract  
submitted by kickingbird at Apr, 28, 2021 from PLoS Pathog. 2021 Apr 27;17(4):e1009561 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
The H7N9 avian influenza virus (AIV) that emerged in China have caused five waves of human infection. Further human cases have been successfully prevented since September 2017 through the use of an H7N9 ...

Xie X, Pang M, Liang S, Lin Y, Zhao Y, Qiu D, Liu. Cellular microRNAs influence replication of H3N2 canine influenza virus in infected cells. Vet Microbiol. 2021 Apr 20;257:109083.  Abstract  
submitted by kickingbird at Apr, 26, 2021 from Vet Microbiol. 2021 Apr 20;257:109083 (via https://www.sciencedirect.com/science/article/pii/S037811352)
MicroRNAs (miRNAs) are known to play important regulatory roles in host-virus interactions. Avian-origin H3N2 canine influenza virus (CIV) has emerged as the most prevalent subtype among dogs in Asia since ...

Jimenez-Bluhm P, Sepulveda A, Baumberger C, Di Pil. Evidence of influenza infection in dogs and cats in central Chile. Prev Vet Med. 2021 Apr 16;191:105349.  Abstract  
submitted by kickingbird at Apr, 25, 2021 from Prev Vet Med. 2021 Apr 16;191:105349 (via https://www.sciencedirect.com/science/article/abs/pii/S01675)
As companion animals, dogs and cats live in close contact with humans, generating the possibility of interspecies pathogen transmission events. Equine origin H3N8 and avian origin H5N1 influenza virus ...

Sch?n J, Breithaupt A, H?per D, King J, Pohlmann A. Neuraminidase-associated plasminogen recruitment enables systemic spread of natural avian Influenza viruses H3N1. PLoS Pathog. 2021 Apr 23;17(4):e1009490.  Abstract  
submitted by kickingbird at Apr, 24, 2021 from PLoS Pathog. 2021 Apr 23;17(4):e1009490 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Repeated outbreaks due to H3N1 low pathogenicity avian influenza viruses (LPAIV) in Belgium were associated with unusually high mortality in chicken in 2019. Those events caused considerable economic losses ...

Adel A, Mosaad Z, Shalaby AG, Selim K, Samy M, Abd. Molecular evolution of the hemagglutinin gene and epidemiological insight into low-pathogenic avian influenza H9N2 viruses in Egypt. Res Vet Sci. 2021 Apr 14;136:540-549.  Abstract  
submitted by kickingbird at Apr, 24, 2021 from Res Vet Sci. 2021 Apr 14;136:540-549 (via https://www.sciencedirect.com/science/article/abs/pii/S00345)
Despite the low pathogenicity of the H9N2 avian influenza viruses, they can induce severe economic losses in various poultry sectors in conjunction with other factors. In Egypt, low-pathogenic avian influenza ...

Ferreira JB, Poljak Z, Friendship R, Nagy é, Widem. Assessment of exposure to influenza A viruses in pigs between weaning and market age. Vet Res. 2021 Apr 21;52(1):60.  Abstract  
submitted by kickingbird at Apr, 23, 2021 from Vet Res. 2021 Apr 21;52(1):60 (via https://veterinaryresearch.biomedcentral.com/articles/10.118)
Influenza A viruses (IAVs) are common causes of respiratory infection in pigs. The objective of this study was to characterize the circulation of IAVs between weaning and market age on the basis of development ...

Kubota-Koketsu R, Yunoki M, Okuno Y, Ikuta K. Virus Neutralization by Human Intravenous Immunoglobulin Against Influenza Virus Subtypes A/H5 and A/H7. Biologics. 2021 Apr 13;15:87-94.  Abstract  
submitted by kickingbird at Apr, 22, 2021 from Biologics. 2021 Apr 13;15:87-94 (via https://www.dovepress.com/virus-neutralization-by-human-intr)
Purpose: Highly pathogenic avian influenza viruses are a threat to human health. Although donor populations have not experienced pandemic, they have been immunized by natural infections and/or vaccinations ...

Gao J, Wan H, Li X, Rakic Martinez M, Klenow L, Ga. Balancing the influenza neuraminidase and hemagglutinin responses by exchanging the vaccine virus backbone. PLoS Pathog. 2021 Apr 19;17(4):e1009171.  Abstract  
submitted by kickingbird at Apr, 20, 2021 from PLoS Pathog. 2021 Apr 19;17(4):e1009171 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Virions are a common antigen source for many viral vaccines. One limitation to using virions is that the antigen abundance is determined by the content of each protein in the virus. This caveat especially ...

Peng C, Zhao P, Jun C, Zhu J, Li Q, Zhao H, Li Y,. Characterization of Four Novel H5N6 Avian Influenza Viruses with the Internal Genes from H5N1 and H9N2 Viruses and Experimental Challenge of Chickens Vaccinated with Current Commercially Available H5. Transbound Emerg Dis. 2021 Apr 19.  Abstract  
submitted by kickingbird at Apr, 20, 2021 from Transbound Emerg Dis. 2021 Apr 19 (via https://onlinelibrary.wiley.com/doi/10.1111/tbed.14110)
Since 2014, highly pathogenic avian influenza H5N6 viruses have been responsible for outbreaks in poultry. In this study, four H5N6 virus strains were isolated from fecal samples of sick white ducks and ...

Nolan KE, Baer LA, Karekar P, Nelson AM, Stanford. Metabolic shifts modulate lung injury caused by infection with H1N1 influenza A virus. Virology. 2021 Apr 6;559:111-119.  Abstract  
submitted by kickingbird at Apr, 19, 2021 from Virology. 2021 Apr 6;559:111-119 (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
Influenza A virus (IAV) infection alters lung epithelial cell metabolism in vitro by promoting a glycolytic shift. We hypothesized that this shift benefits the virus rather than the host and that inhibition ...

Qi Y, Guo W, Liu C, Li W, Gu Y, Li S, Chen X. Seroprevalence of influenza A (H9N2) virus infection among humans in China: A meta-analysis. Microb Pathog. 2021 Apr 14:104881.  Abstract  
submitted by kickingbird at Apr, 19, 2021 from Microb Pathog. 2021 Apr 14:104881 (via https://www.sciencedirect.com/science/article/abs/pii/S08824)
Herein, we conducted a meta-analysis aimed at comprehensively assessing avian influenza A (H9N2) virus infection seroprevalence and infection-related risk factors among humans in China. We reviewed published ...

Nenasheva VV, Nikitenko NA, Stepanenko EA, Makarov. Human TRIM14 protects transgenic mice from influenza A viral infection without activation of other innate immunity pathways. Genes Immun. 2021 Apr 16.  Abstract  
submitted by kickingbird at Apr, 18, 2021 from Genes Immun. 2021 Apr 16 (via https://pubmed.ncbi.nlm.nih.gov/33864033/)
TRIM14 is an important component of innate immunity that defends organism from various viruses. It was shown that TRIM14 restricted influenza A virus (IAV) infection in cell cultures in an interferon-independent ...

Uprety T, Sreenivasan CC, Bhattarai S, Wang D, Kau. Isolation and development of bovine primary respiratory cells as model to study influenza D virus infection. Virology. 2021 Apr 11;559:89-99.  Abstract  
submitted by kickingbird at Apr, 18, 2021 from Virology. 2021 Apr 11;559:89-99 (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
Influenza D virus (IDV) is a novel type of influenza virus that infects and causes respiratory illness in bovines. Lack of host-specific in vitro model that can recapitulate morphology and physiology of ...

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