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2024-5-5 23:05:40
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Fontana J, Steven AC.. At low pH, Influenza virus matrix protein M1 undergoes a conformational change prior to dissociating from the membrane. J Virol. 2013 Mar 6.  Abstract  
submitted by kickingbird at Mar, 10, 2013 from J Virol. 2013 Mar 6 (via http://www.ncbi.nlm.nih.gov/pubmed/23468509)
The M1 matrix protein of influenza A virus, which plays multiple roles in virion assembly and infection, underlies the viral envelope. However, previous studies have given differing accounts of the number ...

GOVORKOVA EA, Baranovich T, Seiler P, Armstrong J,. Antiviral resistance among highly pathogenic influenza A (H5N1) viruses isolated worldwide in 2002-2012 shows need for continued monitoring. Antiviral Res. 2013 Feb 28..  Abstract  
submitted by kickingbird at Mar, 10, 2013 from Antiviral Res. 2013 Feb 28. (via http://www.ncbi.nlm.nih.gov/pubmed/23458714)
Highly pathogenic (HP) H5N1 influenza viruses are evolving pathogens with the potential to cause sustained human-to-human transmission and pandemic virus spread. Specific antiviral drugs can play an important ...

Tamerius JD, Shaman J, Alonso WJ, et al.. Environmental Predictors of Seasonal Influenza Epidemics across Temperate and Tropical Climates. PLoS Pathog 9(3): e1003194. doi:10.1371/journal.pp.  Abstract  
submitted by kickingbird at Mar, 10, 2013 from PLoS Pathog 9(3): e1003194. doi:10.1371/journal.pp (via http://www.plospathogens.org/article/info:doi/10.1371/journa)
Abstract Human influenza infections exhibit a strong seasonal cycle in temperate regions. Recent laboratory and epidemiological evidence suggests that low specific humidity conditions facilitate the ...

Amesh A. Adalja. ECMO for Severe Influenza:Description of a Large French Cohort Study. Center for Biosecurity of UPMC.  Abstract  
submitted by kickingbird at Mar, 9, 2013 from Center for Biosecurity of UPMC (via http://www.upmc-biosecurity.org/)
When a young otherwise healthy individual develops severe acute respiratory distress syndrome (ARDS), rescue therapies are often employed to improve oxygenation, with extra-corporeal membrane oxygenation ...

M Morita, etc.,al. The Lipid Mediator Protectin D1 Inhibits Influenza Virus Replication and Improves Severe Influenza. Cell, 07 March 2013.  Abstract  
submitted by kickingbird at Mar, 8, 2013 from Cell, 07 March 2013 (via http://www.cell.com/retrieve/pii/S009286741300216X?cc=y)
Influenza A viruses are a major cause of mortality. Given the potential for future lethal pandemics, effective drugs are needed for the treatment of severe influenza such as that caused by H5N1 viruses. ...

L Pena, etc.,al. Influenza viruses with rearranged genomes as live-attenuated vaccines. J Virol, published online Feb 28.  Abstract  
submitted by kickingbird at Mar, 8, 2013 from J Virol, published online Feb 28 (via http://jvi.asm.org/content/early/2013/02/20/JVI.02490-12.sho)
H5N1 and H9N2 avian influenza subtypes top the World Health Organization's list for the greatest pandemic potential. Inactivated H5N1 vaccines induce limited immune responses and, in the case of live attenuated ...

Noti JD, Blachere FM, McMillen CM, Lindsley WG, Ka. High Humidity Leads to Loss of Infectious Influenza Virus from Simulated Coughs. PLoS ONE 8(2): e57485. doi:10.1371/journal.pone.00.  Abstract  
submitted by kickingbird at Mar, 8, 2013 from PLoS ONE 8(2): e57485. doi:10.1371/journal.pone.00 (via http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjourna)
Abstract Background The role of relative humidity in the aerosol transmission of influenza was examined in a simulated examination room containing coughing and breathing manikins. Methods Nebulized ...

ME Sundaram, etc.,al. Vitamin D is not associated with serologic response to influenza vaccine in adults over 50 years old. Vaccine, published online Feb 28.  Abstract  
submitted by kickingbird at Mar, 8, 2013 from Vaccine, published online Feb 28 (via http://www.sciencedirect.com/science/article/pii/S0264410X13)
Abstract Vitamin D deficiency has been implicated in risk of respiratory illness. We determined whether serum vitamin D levels are related to influenza vaccine response measured by hemagglutinin antibody ...

Dobrovolny HM, Reddy MB, Kamal MA, Rayner CR, Beau. Assessing Mathematical Models of Influenza Infections Using Features of the Immune Response. PLoS ONE 8(2): e57088. doi:10.1371/journal.pone.00.  Abstract  
submitted by kickingbird at Mar, 8, 2013 from PLoS ONE 8(2): e57088. doi:10.1371/journal.pone.00 (via http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjourna)
The role of the host immune response in determining the severity and duration of an influenza infection is still unclear. In order to identify severity factors and more accurately predict the course of ...

EJ Nicoli, etc.,al. Influenza and RSV make a modest contribution to invasive pneumococcal disease incidence in the UK. J Infect, published online Mar 5.  Abstract  
submitted by kickingbird at Mar, 8, 2013 from J Infect, published online Mar 5 (via http://www.sciencedirect.com/science/article/pii/S0163445313)
Summary Objectives The common seasonality of incidence of invasive pneumococcal disease (IPD) and viral respiratory infections has long been recognized, however, the extent to which this affects the ...

Wilson HM, Hall JS, Flint PL, Franson JC, Ely CR,. High Seroprevalence of Antibodies to Avian Influenza Viruses among Wild Waterfowl in Alaska: Implications for Surveillance. PLoS ONE 8(3): e58308. doi:10.1371/journal.pone.00.  Abstract  
submitted by kickingbird at Mar, 7, 2013 from PLoS ONE 8(3): e58308. doi:10.1371/journal.pone.00 (via http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjourna)
We examined seroprevalence (presence of detectable antibodies in serum) for avian influenza viruses (AIV) among 4,485 birds, from 11 species of wild waterfowl in Alaska (1998–2010), sampled during breeding/molting ...

Suzanne E. Ohmit,etc.,al. Influenza Vaccine Effectiveness in the Community and the Household. Clin Infect Dis. (2013).  Abstract  
submitted by kickingbird at Mar, 7, 2013 from Clin Infect Dis. (2013) (via http://cid.oxfordjournals.org/content/early/2013/02/14/cid.c)
Background.?There is a recognized need to determine influenza vaccine effectiveness on an annual basis and a long history of studying respiratory illnesses in households. Methods.?We recruited 328 households ...

YAMAMOTO N, Soda K, Sakoda Y, Okamatsu M, et al. Proteins of duck influenza virus responsible for acquisition of pathogenicity in chickens. Virus Res. 2013 Feb 19. pii: S0168-1702(13)00050-6.  Abstract  
submitted by kickingbird at Mar, 6, 2013 from Virus Res. 2013 Feb 19. pii: S0168-1702(13)00050-6 (via http://www.ncbi.nlm.nih.gov/pubmed/23434880)
Influenza virus rgVac1sub-P0 (H5N1) (rgVac1-P0), in which a pair of dibasic amino acid residues was introduced at the cleavage site of the HA of a reassortant of H5N2 and H7N1 viruses of duck origin, was ...

Zaraket H, Bridges OA, Russell CJ.. The pH of Activation of the Hemagglutinin Protein Regulates H5N1 Influenza Virus Replication and Pathogenesis in Mice. J Virol. 2013 Feb 28.  Abstract  
submitted by kickingbird at Mar, 6, 2013 from J Virol. 2013 Feb 28 (via http://www.ncbi.nlm.nih.gov/pubmed/23449784)
After receptor binding and internalization during influenza virus entry, the hemagglutinin (HA) protein is triggered by low pH to undergo irreversible conformational changes that mediate membrane fusion. ...

TSE LV, Marcano VC, Huang W, Pocwierz MS, et al. Plasmin-mediated activation of pandemic H1N1 influenza virus hemagglutinin independent of the viral neuraminidase. J Virol. 2013 Feb 28.  Abstract  
submitted by kickingbird at Mar, 6, 2013 from J Virol. 2013 Feb 28 (via http://www.ncbi.nlm.nih.gov/pubmed/23449787)
Influenza virus is well recognized to modulate host tropism and pathogenesis based on mutations in the proteolytic cleavage site of the viral hemagglutinin (HA), which activates HA and exposes the fusion ...

DERMODY TS, Sandri-Goldin RM, Shenk T. A New Determinant of H5N1 Influenza Virus Pathogenesis in Mammals. J Virol. 2013 Feb 28.  Abstract  
submitted by kickingbird at Mar, 6, 2013 from J Virol. 2013 Feb 28 (via http://www.ncbi.nlm.nih.gov/pubmed/23449798)
In this issue of the Journal of Virology, we publish a paper by Hassan Zaraket, Olga A. Bridges, and Charles J. Russell from St. Jude Children's Research Hospital reporting a sequence polymorphism in the ...

TAKEMAE N, Nguyen T, Ngo LT, Hiromoto Y, et al. Antigenic variation of H1N1, H1N2 and H3N2 swine influenza viruses in Japan and Vietnam. Arch Virol. 2013 Feb 23.  Abstract  
submitted by kickingbird at Mar, 6, 2013 from Arch Virol. 2013 Feb 23 (via http://www.ncbi.nlm.nih.gov/pubmed/23435952)
The antigenicity of the influenza A virus hemagglutinin is responsible for vaccine efficacy in protecting pigs against swine influenza virus (SIV) infection. However, the antigenicity of SIV strains currently ...

H.K.K. Perera et al. Swine Influenza in Sri Lanka. EID Volume 19, Number 3—March 2013.  Abstract  
submitted by kickingbird at Mar, 2, 2013 from EID Volume 19, Number 3—March 2013 (via http://wwwnc.cdc.gov/eid/article/19/3/12-0945_article.htm)
Abstract To study influenza viruses in pigs in Sri Lanka, we examined samples from pigs at slaughterhouses. Influenza (H3N2) and A(H1N1)pdm09 viruses were prevalent during 2004–2005 and 2009–2012, respectively. ...

R. Bodewes et al. Recurring Influenza B Virus Infections in Seals. EID Volume 19, Number 3—March 2013.  Abstract  
submitted by kickingbird at Mar, 2, 2013 from EID Volume 19, Number 3—March 2013 (via http://wwwnc.cdc.gov/eid/article/19/3/12-0965_article.htm)
To the Editor: Until 1999, influenza B virus was considered to infect humans only. However, more recent data proved that harbor seals (Phoca vitulina) and gray seals (Halichoerus grypus) also can be infected ...

Elizabeth Miller,etc.,al. Risk of narcolepsy in children and young people receiving AS03 adjuvanted pandemic A/H1N1 2009 influenza vaccine: retrospective analysis. BMJ 2013;346:f794.  Abstract  
submitted by kickingbird at Feb, 28, 2013 from BMJ 2013;346:f794 (via http://www.bmj.com/content/346/bmj.f794)
Objective To evaluate the risk of narcolepsy in children and adolescents in England targeted for vaccination with ASO3 adjuvanted pandemic A/H1N1 2009 vaccine (Pandemrix) from October 2009. Design Retrospective ...

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