Hu J, Zeng Z, Chen X, Zhang M, Hu Z, Gu M, Wang X,. Phosphorylation of PB2 at serine 181 restricts viral replication and virulence of the highly pathogenic H5N1 avian influenza virus in mice. Virol Sin. 2023 Dec 14:S1995-820X(23)00155-4. Abstract
submitted by kickingbird at Dec, 18, 2023 from Virol Sin. 2023 Dec 14:S1995-820X(23)00155-4 (via https://www.sciencedirect.com/science/article/pii/S1995820X2)
Influenza A virus (IAV) still poses a pandemic threat to public health, causing a high mortality rate annually and during pandemic years. Posttranslational modification of the viral protein plays a substantial ... Chenavier F, Estrozi LF, Teulon JM, Zarkadas E, Fr. Cryo-EM structure of influenza helical nucleocapsid reveals NP-NP and NP-RNA interactions as a model for the genome encapsidation. Sci Adv. 2023 Dec 15;9(50):eadj9974. Abstract
submitted by kickingbird at Dec, 17, 2023 from Sci Adv. 2023 Dec 15;9(50):eadj9974 (via https://www.science.org/doi/10.1126/sciadv.adj9974)
Influenza virus genome encapsidation is essential for the formation of a helical viral ribonucleoprotein (vRNP) complex composed of nucleoproteins (NP), the trimeric polymerase, and the viral genome. Although ... Dosey A, Ellis D, Boyoglu-Barnum S, Syeda H, Saund. Combinatorial immune refocusing within the influenza hemagglutinin RBD improves cross-neutralizing antibody responses. Cell Rep. 2023 Dec 13;42(12):113553. Abstract
submitted by kickingbird at Dec, 17, 2023 from Cell Rep. 2023 Dec 13;42(12):113553 (via https://www.cell.com/cell-reports/fulltext/S2211-1247(23)015)
The receptor-binding domain (RBD) of influenza virus hemagglutinin (HA) elicits potently neutralizing yet mostly strain-specific antibodies. Here, we evaluate the ability of several immunofocusing techniques ... Bialy D, Richardson S, Chrzastek K, Bhat S, Polo N. Recombinant A(H6N1)-H274Y avian influenza virus with dual drug resistance does not require permissive mutations to retain the replicative fitness in vitro and in ovo. Virology. 2023 Dec 2;590:109954. Abstract
submitted by kickingbird at Dec, 14, 2023 from Virology. 2023 Dec 2;590:109954 (via https://www.sciencedirect.com/science/article/pii/S004268222)
The possible emergence of drug-resistant avian flu raises concerns over the limited effectiveness of currently approved antivirals (neuraminidase inhibitors - NAIs) in the hypothetical event of a zoonotic ... Trov?o NS, Khan SM, Lemey P, Nelson MI, Cherry JL. Comparative evolution of influenza A virus H1 and H3 head and stalk domains across host species. mBio. 2023 Dec 11:e0264923. Abstract
submitted by kickingbird at Dec, 12, 2023 from mBio. 2023 Dec 11:e0264923 (via https://journals.asm.org/doi/10.1128/mbio.02649-23)
For decades, researchers have studied the rapid evolution of influenza A viruses for vaccine design and as a useful model system for the study of host/parasite evolution. By performing an exhaustive analysis ... Guan W, Qu R, Shen L, Mai K, Pan W, Lin Z, Chen L,. Baloxavir marboxil use for critical human infection of avian influenza A H5N6 virus. Med. 2023 Dec 5:S2666-6340(23)00361-6. Abstract
submitted by kickingbird at Dec, 11, 2023 from Med. 2023 Dec 5:S2666-6340(23)00361-6 (via https://www.cell.com/med/fulltext/S2666-6340(23)00361-6)
Background: Recent outbreaks of avian influenza and ongoing virus reassortment have drawn focus on spill-over infections. The increase in human infections with highly pathogenic avian influenza H5N6 virus ... Lijuan Liang, etc.,al. Genetic variation and evolution of influenza viruses isolated from co-infection cases in Guangdong Province. DOI: 10.3760/cma.j.cn112309-20230717-00213. Abstract
submitted by kickingbird at Dec, 11, 2023 from DOI: 10.3760/cma.j.cn112309-20230717-00213 (via https://rs.yiigle.com/cmaid/1482234)
Objective To analyze and reveal the genetic evolution and variation of influenza viruses in cases of co-infection in Guangdong Province.Methods Throat swab samples were collected from four cases of H1N1pdm ... Wang X, Zheng H, Gao R, Ren L, Jin M, Ji Z, Wang X. Genetically Related Avian Influenza H7N9 Viruses Exhibit Different Pathogenicity in Mice. Animals (Basel). 2023 Nov 28;13(23):3680. Abstract
submitted by kickingbird at Dec, 10, 2023 from Animals (Basel). 2023 Nov 28;13(23):3680 (via https://www.mdpi.com/2076-2615/13/23/3680)
Avian influenza viruses can cross species barriers and adapt to mammals. The H7N9 subtype AIV that emerged in China in 2013 caused 1568 human infections, with a mortality rate of nearly 40%. We conducted ... Zhao W, Liu X, Zhang X, Qiu Z, Jiao J, Li Y, Gao R. Virulence and transmission characteristics of clade 2.3.4.4b H5N6 subtype avian influenza viruses possessing different internal gene constellations. Virulence. 2023 Dec;14(1):2250065. Abstract
submitted by kickingbird at Dec, 9, 2023 from Virulence. 2023 Dec;14(1):2250065 (via https://www.tandfonline.com/doi/full/10.1080/21505594.2023.2)
Clade 2.3.4.4 H5N6 avian influenza virus (AIV) has been predominant in poultry in China, and the circulating haemagglutinin (HA) gene has changed from clade 2.3.4.4h to clade 2.3.4.4b in recent years. ... Caceres CJ, Gay LC, Faccin FC, Pérez DR. Use of Reverse Genetics for the Generation of Recombinant Influenza Viruses Carrying Nanoluciferase. Methods Mol Biol. 2024;2733:47-74. Abstract
submitted by kickingbird at Dec, 9, 2023 from Methods Mol Biol. 2024;2733:47-74 (via https://link.springer.com/protocol/10.1007/978-1-0716-3533-9)
Influenza A (FLUAV) and influenza B (FLUBV) viruses are human and/or animal pathogens widely studied due to their importance to public health and animal production. Both FLUAV and FLUBV possess a genome ... Kessler S, García-Sastre A, Schwemmle M, Ciminski. Reverse Genetics of Bat Influenza A Viruses. Methods Mol Biol. 2024;2733:75-86. Abstract
submitted by kickingbird at Dec, 9, 2023 from Methods Mol Biol. 2024;2733:75-86 (via https://link.springer.com/protocol/10.1007/978-1-0716-3533-9)
New World fruit bats were recently found to harbor two distinct and previously unknown influenza A viruses (IAVs) of the subtypes H17N10 and H18N11. Although viral genome sequences were detected in the ... Zhang L, Shao Y, Wang Y, Yang Q, Guo J, Gao GF, De. Twenty natural amino acid substitution screening at the last residue 121 of influenza A virus NS2 protein reveals the critical role of NS2 in promoting virus genome replication by coordinating with vi. J Virol. 2023 Dec 6:e0116623. Abstract
submitted by kickingbird at Dec, 7, 2023 from J Virol. 2023 Dec 6:e0116623 (via https://journals.asm.org/doi/10.1128/jvi.01166-23)
The intrinsic mechanisms of influenza RNA polymerase (FluPol) in catalyzing viral genome transcription and replication have been largely resolved. However, the mechanisms of how transcription and replication ... Chua SCJH, Cui J, Sachaphibulkij K, Tan ISL, Tan H. The ER-Golgi transport of influenza virus through NS1-Sec13 association during virus replication. Microbiol Spectr. 2023 Dec 1:e0260923. Abstract
submitted by kickingbird at Dec, 2, 2023 from Microbiol Spectr. 2023 Dec 1:e0260923 (via https://journals.asm.org/doi/10.1128/spectrum.02609-23)
Influenza A virus is a respiratory virus that can cause complications such as acute bronchitis and secondary bacterial pneumonia. Drug therapies and vaccines are available against influenza, albeit limited ... Hu Y, Jiang L, Wang G, Song Y, Shan Z, Wang X, Den. M6PR interacts with the HA2 subunit of influenza A virus to facilitate the fusion of viral and endosomal membranes. Sci China Life Sci. 2023 Nov 22. Abstract
submitted by kickingbird at Dec, 2, 2023 from Sci China Life Sci. 2023 Nov 22 (via https://link.springer.com/article/10.1007/s11427-023-2471-4)
Influenza A virus (IAV) commandeers numerous host cellular factors for successful replication. However, very few host factors have been revealed to be involved in the fusion of viral envelope and late ... Kang S, Vu TH, Heo J, Kim C, Lillehoj HS, Hong YH. Analysis of miRNA expression in the trachea of Ri chicken infected with the highly pathogenic avian influenza H5N1 virus. J Vet Sci. 2023 Sep;24(5):e73. Abstract
submitted by kickingbird at Dec, 1, 2023 from J Vet Sci. 2023 Sep;24(5):e73 (via https://vetsci.org/DOIx.php?id=10.4142/jvs.23141)
Background: Highly pathogenic avian influenza virus (HPAIV) is considered a global threat to both human health and the poultry industry. MicroRNAs (miRNA) can modulate the immune system by affecting gene ... K?nig S, Schroeder J, Nietzsche S, Heinekamp T, Br. The influenza A virus promotes fungal growth of Aspergillus fumigatus via direct interaction in vitro. Microbes Infect. 2023 Nov 24:105264. Abstract
submitted by kickingbird at Nov, 29, 2023 from Microbes Infect. 2023 Nov 24:105264 (via https://www.sciencedirect.com/science/article/pii/S128645792)
Seasonal influenza A virus (IAV) infections still pose a major burden for public health worldwide. Severe disease progression or even death is often related to superinfections of the virus and a secondary ... Liao Q, Shen J, Chen Y, Shu Y. Mendelian randomization study on the causal effect of serum IgA levels on H7N9 avian influenza A virus susceptibility. J Med Virol. 2023 Nov;95(11):e29266. Abstract
submitted by kickingbird at Nov, 29, 2023 from J Med Virol. 2023 Nov;95(11):e29266 (via https://onlinelibrary.wiley.com/doi/10.1002/jmv.29266)
Avian influenza A viruses (IAVs) that cross the species barrier to infect humans have the potential to initiate a new pandemic. However, the host factors influencing avian IAV infection remain poorly understood. ... Van Reeth K, Parys A, Gracia JCM, Trus I, Chiers K. Sequential vaccinations with divergent H1N1 influenza virus strains induce multi-H1 clade neutralizing antibodies in swine. Nat Commun. 2023 Nov 27;14(1):7745. Abstract
submitted by kickingbird at Nov, 29, 2023 from Nat Commun. 2023 Nov 27;14(1):7745 (via https://www.nature.com/articles/s41467-023-43339-3)
Vaccines that protect against any H1N1 influenza A virus strain would be advantageous for use in pigs and humans. Here, we try to induce a pan-H1N1 antibody response in pigs by sequential vaccination with ... Komu JG, Nguyen HD, Takeda Y, Fukumoto S, Imai K,. Challenges for Precise Subtyping and Sequencing of a H5N1 Clade 2.3.4.4b Highly Pathogenic Avian Influenza Virus Isolated in Japan in the 2022-2023 Season Using Classical Serological and Molecular Met. Viruses. 2023 Nov 18;15(11):2274. Abstract
submitted by kickingbird at Nov, 29, 2023 from Viruses. 2023 Nov 18;15(11):2274 (via https://www.mdpi.com/1999-4915/15/11/2274)
The continuous evolution of H5Nx highly pathogenic avian influenza viruses (HPAIVs) is a major concern for accurate diagnosis. We encountered some challenges in subtyping and sequencing a recently isolated ... Nan Chen, etc.,al. Establishment of an in vivo neutralization model based on H5N1 pseudovirus. DOI: 10.3760/cma.j.cn112309-20230206-00023. Abstract
submitted by kickingbird at Nov, 27, 2023 from DOI: 10.3760/cma.j.cn112309-20230206-00023 (via https://rs.yiigle.com/cmaid/1464197)
Objective To establish an in vivo infection model of H5N1 pseudovirus and to detect the neutralizing activity of FHA3 antibody using this model.Methods Based on the sequence information of hemagglutinin ... 5131 items, 20/Page, Page[9/257][|<<] [|<] [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [>|] [>>|] |
Related Pages:
Browse by Category
Learn about the flu news, articles, events and more
Subscribe to the weekly F.I.C newsletter!
|
- 
