Ichimiya T, Okamatsu M, Kinoshita T, Kobayashi D,. Sulfated glycans containing NeuAcα2-3Gal facilitate the propagation of human H1N1 influenza A viruses in eggs. Virology. 2021 Jun 25;562:29-39. Abstract
submitted by kickingbird at Jul, 12, 2021 from Virology. 2021 Jun 25;562:29-39 (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
When human influenza viruses are isolated and passaged in chicken embryos, variants with amino acid substitutions around the receptor binding site of hemagglutinin (HA) are selected; however, the mechanisms ... Wang Y, Yuan C, Xu X, Chong TH, Zhang L, Cheung PP. The mechanism of action of T-705 as a unique delayed chain terminator on influenza viral polymerase transcription. Biophys Chem. 2021 Jun 25;277:106652. Abstract
submitted by kickingbird at Jul, 10, 2021 from Biophys Chem. 2021 Jun 25;277:106652 (via https://www.sciencedirect.com/science/article/abs/pii/S03014)
Favipiravir (T-705) has been developed as a potent anti-influenza drug and exhibited a strong inhibition effect against a broad spectrum of RNA viruses. Its active form, ribofuranosyl-triphosphate (T-705-RTP), ... Leyson CM, Youk S, Ferreira HL, Suarez DL, Pantin-. Multiple gene segments are associated with enhanced virulence of clade 2.3.4.4 H5N8 highly pathogenic avian influenza virus in mallards. J Virol. 2021 Jul 7:JVI0095521. Abstract
submitted by kickingbird at Jul, 8, 2021 from J Virol. 2021 Jul 7:JVI0095521 (via https://journals.asm.org/doi/10.1128/JVI.00955-21)
Highly pathogenic avian influenza (HPAI) viruses from the H5Nx Goose/Guangdong/96 lineage continue to cause outbreaks in domestic and wild bird populations. Two distinct genetic groups of H5N8 HPAI viruses, ... Yu JL, Hou S, Feng YT, Bu G, Chen QQ, Meng ZQ, Din. Emergence of a young case infected with avian influenza A (H5N6) in Anhui Province, East China during the COVID-19 pandemic. J Med Virol. 2021 Jul 7. Abstract
submitted by kickingbird at Jul, 8, 2021 from J Med Virol. 2021 Jul 7 (via https://onlinelibrary.wiley.com/doi/10.1002/jmv.27179)
In the context of the COVID-19 pandemic, we investigated the epidemiological and clinical characteristics of a young patient infected by avian influenza A (H5N6) virus in Anhui Province, East China, and ... Kang YM, Cho HK, Kim JH, Lee SJ, Park SJ, Kim DY,. Single dose of multi-clade virus-like particle vaccine protects chickens against clade 2.3.2.1 and clade 2.3.4.4 highly pathogenic avian influenza viruses. Sci Rep. 2021 Jul 2;11(1):13786. Abstract
submitted by kickingbird at Jul, 7, 2021 from Sci Rep. 2021 Jul 2;11(1):13786 (via https://www.nature.com/articles/s41598-021-93060-8)
Virus-like particles (VLPs) are recognized as an alternative vaccine platform that provide effective protection against various highly pathogenic avian influenza viruses (HPAIVs). Here, we developed multi-clade ... Rahman MM, Nooruzzaman M, Kabiraj CK, Mumu TT, Das. Surveillance on respiratory diseases reveals enzootic circulation of both H5 and H9 avian influenza viruses in small-scale commercial layer farms of Bangladesh. Zoonoses Public Health. 2021 Jul 4.. Abstract
submitted by kickingbird at Jul, 7, 2021 from Zoonoses Public Health. 2021 Jul 4. (via https://onlinelibrary.wiley.com/doi/10.1111/zph.12879)
Poultry production in Bangladesh has been experiencing H5N1 highly pathogenic avian influenza (HPAI) and H9N2 low pathogenic avian influenza (LPAI) for the last 14 years. Vaccination of chickens against ... Bissinger T, Wu Y, Marichal-Gallardo P, Riedel D,. Towards integrated production of an influenza A vaccine candidate with MDCK suspension cells. Biotechnol Bioeng. 2021 Jul 5. Abstract
submitted by kickingbird at Jul, 7, 2021 from Biotechnol Bioeng. 2021 Jul 5 (via https://onlinelibrary.wiley.com/doi/10.1002/bit.27876)
Seasonal influenza epidemics occur both in northern and southern hemispheres every year. Despite the differences in influenza virus surface antigens and virulence of seasonal subtypes, manufacturers are ... Cáceres CJ, Cardenas-Garcia S, Jain A, Gay LC, Car. Development of a Novel Live Attenuated Influenza A Virus Vaccine Encoding the IgA-Inducing Protein. Vaccines (Basel). 2021 Jun 27;9(7):703. Abstract
submitted by kickingbird at Jul, 4, 2021 from Vaccines (Basel). 2021 Jun 27;9(7):703 (via https://www.mdpi.com/2076-393X/9/7/703)
Live attenuated influenza virus (LAIV) vaccines elicit a combination of systemic and mucosal immunity by mimicking a natural infection. To further enhance protective mucosal responses, we incorporated ... Yoo DS, Chun B, Min KD, Lim JS, Moon OK, Lee KN. Elucidating the Local Transmission Dynamics of Highly Pathogenic Avian Influenza H5N6 in the Republic of Korea by Integrating Phylogenetic Information. Pathogens. 2021 Jun 2;10(6):691. Abstract
submitted by kickingbird at Jul, 4, 2021 from Pathogens. 2021 Jun 2;10(6):691 (via https://www.mdpi.com/2076-0817/10/6/691)
Highly pathogenic avian influenza (HPAI) virus is one of the most virulent and infectious pathogens of poultry. As a response to HPAI epidemics, veterinary authorities implement preemptive depopulation ... Liang Y, Krog JS, Ryt-Hansen P, Pedersen AG, Kvisg. Molecular Characterization of Highly Pathogenic Avian Influenza Viruses H5N6 Detected in Denmark in 2018-2019. Viruses. 2021 Jun 2;13(6):1052. Abstract
submitted by kickingbird at Jul, 4, 2021 from Viruses. 2021 Jun 2;13(6):1052 (via https://www.mdpi.com/1999-4915/13/6/1052)
Beginning in late 2017, highly pathogenic avian influenza (HPAI) H5N6 viruses caused outbreaks in wild birds and poultry in several European countries. H5N6 viruses were detected in 43 wild birds found ... Jeong S, Kwon JH, Lee SH, Kim YJ, Jeong JH, Park J. Subclinical Infection and Transmission of Clade 2.3.4.4 H5N6 Highly Pathogenic Avian Influenza Virus in Mandarin Duck (Aix galericulata) and Domestic Pigeon (Columbia livia domestica). Viruses. 2021 Jun 4;13(6):1069. Abstract
submitted by kickingbird at Jul, 4, 2021 from Viruses. 2021 Jun 4;13(6):1069 (via https://www.mdpi.com/1999-4915/13/6/1069)
Since 2014, H5Nx clade 2.3.4.4 highly pathogenic avian influenza viruses (HPAIV) have caused outbreaks in wild birds and poultry in multiple continents, including Asia, Europe, Africa, and North America. ... White CL, Chiem K, Perez DR, Santos J, Cardenas Ga. A New Master Donor Virus for the Development of Live-Attenuated Influenza B Virus Vaccines. Viruses. 2021 Jun 30;13(7):1278. Abstract
submitted by kickingbird at Jul, 4, 2021 from Viruses. 2021 Jun 30;13(7):1278 (via https://www.mdpi.com/1999-4915/13/7/1278)
Influenza B viruses (IBV) circulate annually, with young children, the elderly and immunocompromised individuals being at high risk. Yearly vaccinations are recommended to protect against seasonally influenza ... Bolton JS, Klim H, Wellens J, Edmans M, Obolski U,. An Antigenic Thrift-Based Approach to Influenza Vaccine Design. Vaccines (Basel). 2021 Jun 16;9(6):657. Abstract
submitted by kickingbird at Jul, 4, 2021 from Vaccines (Basel). 2021 Jun 16;9(6):657 (via https://www.mdpi.com/2076-393X/9/6/657)
The antigenic drift theory states that influenza evolves via the gradual accumulation of mutations, decreasing a host's immune protection against previous strains. Influenza vaccines are designed accordingly, ... Wiggins KB, Smith MA, Schultz-Cherry S. The Nature of Immune Responses to Influenza Vaccination in High-Risk Populations. Viruses. 2021 Jun 9;13(6):1109. Abstract
submitted by kickingbird at Jul, 4, 2021 from Viruses. 2021 Jun 9;13(6):1109 (via https://www.mdpi.com/1999-4915/13/6/1109)
The current pandemic has brought a renewed appreciation for the critical importance of vaccines for the promotion of both individual and public health. Influenza vaccines have been our primary tool for ... Chrzastek K, Segovia K, Torchetti M, Killian ML, P. Virus Adaptation Following Experimental Infection of Chickens with a Domestic Duck Low Pathogenic Avian Influenza Isolate from the 2017 USA H7N9 Outbreak Identifies Polymorphic Mutations in Multiple G. Viruses. 2021 Jun 18;13(6):1166. Abstract
submitted by kickingbird at Jul, 4, 2021 from Viruses. 2021 Jun 18;13(6):1166 (via https://www.mdpi.com/1999-4915/13/6/1166)
In March 2017, highly pathogenic (HP) and low pathogenic (LP) avian influenza virus (AIV) subtype H7N9 were detected from poultry farms and backyard birds in several states in the southeast United States. ... Soh YQS, Malone KD, Eguia RT, Bloom JD. Comprehensive Profiling of Mutations to Influenza Virus PB2 That Confer Resistance to the Cap-Binding Inhibitor Pimodivir. Viruses. 2021 Jun 22;13(7):1196. Abstract
submitted by kickingbird at Jul, 4, 2021 from Viruses. 2021 Jun 22;13(7):1196 (via https://www.mdpi.com/1999-4915/13/7/1196)
Antivirals are used not only in the current treatment of influenza but are also stockpiled as a first line of defense against novel influenza strains for which vaccines have yet to be developed. Identifying ... Xiao Y, Zhang W, Pan M, Bauer DLV, Bi Y, Cao M, Fo. A synergistic effect between 3´ terminal noncoding and adjacent coding regions of influenza A virus HA segment on template preference. J Virol. 2021 Jun 30:JVI0087821. Abstract
submitted by kickingbird at Jul, 2, 2021 from J Virol. 2021 Jun 30:JVI0087821 (via https://journals.asm.org/doi/10.1128/JVI.00878-21)
The influenza A virus genome is comprised of eight single-stranded negative-sense viral RNA (vRNA) segments. Each of the eight vRNA segments contains segment-specific nonconserved noncoding regions (NCRs) ... Yu J, Huang C, Sheng Z, Wang Z, Li F, Wang D. Identification of One Critical Amino Acid Residue of the Nucleoprotein as a Determinant for in vitro Viral Replication Fitness of Influenza D Virus. J Virol. 2021 Jun 30:JVI0097121. Abstract
submitted by kickingbird at Jul, 2, 2021 from J Virol. 2021 Jun 30:JVI0097121 (via https://journals.asm.org/doi/10.1128/JVI.00971-21)
The newly identified influenza D virus (IDV) of the Orthomyxoviridae family has a wide host range with broad geographical distribution. Despite the first appearance in U.S. pig herds in 2011, subsequent ... Wang Y, Niu S, Zhang B, Yang C, Zhou Z. The whole genome analysis for the first human infection with H10N3 influenza virus in China. J Infect. 2021 Jun 27:S0163-4453(21)00318-2. Abstract
submitted by kickingbird at Jul, 2, 2021 from J Infect. 2021 Jun 27:S0163-4453(21)00318-2 (via https://www.journalofinfection.com/article/S0163-4453(21)003)
A strain of H10N3 influenza virus, A/Jiangsu/428/2021/H10N3, was isolated from patient in Jiangsu province, eastern China. Phylogenetic analysis illustrated this human H10N3 virus was a low pathogenic ... Cui J, Cui P, Shi J, Fan W, Xing X, Gu W, Zhang Y,. Continued evolution of H6 avian influenza viruses isolated from farms in China between 2014 and 2018. Transbound Emerg Dis. 2021 Jun 30. Abstract
submitted by kickingbird at Jul, 2, 2021 from Transbound Emerg Dis. 2021 Jun 30 (via https://onlinelibrary.wiley.com/doi/10.1111/tbed.14212)
H6 avian influenza virus (AIV) is one of the most prevalent AIV subtypes in the world. Our previous studies have demonstrated that H6 AIVs isolated from live poultry markets pose a potential threat to ... 7725 items, 20/Page, Page[95/387][|<<] [|<] [91] [92] [93] [94] [95] [96] [97] [98] [99] [100] [>|] [>>|] |
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