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2024-7-17 17:33:53
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Chiem K, Nogales A, Martinez-Sobrido L. Generation, Characterization, and Applications of Influenza A Reporter Viruses. Methods Mol Biol. 2022;2524:249-268.  Abstract  
submitted by kickingbird at Jul, 14, 2022 from Methods Mol Biol. 2022;2524:249-268 (via https://link.springer.com/protocol/10.1007/978-1-0716-2453-1)
Secondary experimental procedures such as immunostaining have been utilized to study wild-type influenza A viruses (IAV) but are inadequate to rapidly determine the virus in infected cells or for the high-throughput ...

Chen J, Xu L, Liu T, Xie S, Li K, Li X, Zhang M, W. Novel Reassortant Avian Influenza A(H5N6) Virus, China, 2021. Emerg Infect Dis. 2022 Jul 12;28(8).  Abstract  
submitted by kickingbird at Jul, 13, 2022 from Emerg Infect Dis. 2022 Jul 12;28(8) (via https://wwwnc.cdc.gov/eid/article/28/8/21-2241_article)
Although reports of human infection with influenza A(H5N6) increased in 2021, reports of similar H5N6 virus infection in poultry are few. We detected 10 avian influenza A(H5N6) clade 2.3.4.4b viruses in ...

Xu H, Palpant T, Weinberger C, Shaw DE. Characterizing Receptor Flexibility to Predict Mutations That Lead to Human Adaptation of Influenza Hemagglutinin. J Chem Theory Comput. 2022 Jul 11.  Abstract  
submitted by kickingbird at Jul, 13, 2022 from J Chem Theory Comput. 2022 Jul 11 (via https://pubs.acs.org/doi/10.1021/acs.jctc.1c01044)
A key step in the emergence of human pandemic influenza strains has been a switch in binding preference of the viral glycoprotein hemagglutinin (HA) from avian to human sialic acid (SA) receptors. The ...

Song H, Liu X, Gao X, Li J, Shang Y, Gao W, Li Y,. Transcriptome analysis of pre-immune state induced by interferon gamma inhibiting the replication of H9N2 avian influenza viruses in chicken embryo fibroblasts. Infect Genet Evol. 2022 Jul 7:105332.  Abstract  
submitted by kickingbird at Jul, 13, 2022 from Infect Genet Evol. 2022 Jul 7:105332 (via https://www.sciencedirect.com/science/article/pii/S156713482)
Interferon (IFN), a critical antiviral cytokine produced by pathogens-induced cells, plays an important role in host innate immune system. In this study, to investigate the inhibition effect of IFN on ...

Song Y, Zhu W, Wang Y, Deng L, Ma Y, Dong C, Gonza. Layered protein nanoparticles containing influenza B HA stalk induced sustained cross-protection against viruses spanning both viral lineages. Biomaterials. 2022 Jul 4;287:121664.  Abstract  
submitted by kickingbird at Jul, 13, 2022 from Biomaterials. 2022 Jul 4;287:121664 (via https://www.sciencedirect.com/science/article/abs/pii/S01429)
The influenza epidemics pose a significant threat to public health. Of them, type B influenza coincided with several severe flu outbreaks. The efficacy of the current seasonal flu vaccine is limited due ...

Xu W, Wang Y, Li L, Qu X, Liu Q, Li T, Wu S, Liao. Transmembrane domain of IFITM3 is responsible for its interaction with influenza virus HA 2 subunit. Xu W, Wang Y, Li L, Qu X, Liu Q, Li T, Wu S, Liao.  Abstract  
submitted by kickingbird at Jul, 11, 2022 from Xu W, Wang Y, Li L, Qu X, Liu Q, Li T, Wu S, Liao (via https://www.sciencedirect.com/science/article/pii/S1995820X2)
Interferon-inducible transmembrane protein 3 (IFITM3) inhibits influenza virus infection by blocking viral membrane fusion, but the exact mechanism remains elusive. Here, we investigated the function and ...

Baek YG, Lee YN, Park YR, Chung DH, Kwon JH, Si YJ. Evolution, Transmission, and Pathogenicity of High Pathogenicity Avian Influenza Virus A (H5N8) Clade 2.3.4.4, South Korea, 2014-2016. Front Vet Sci. 2022 Jun 21;9:906944.  Abstract  
submitted by kickingbird at Jul, 9, 2022 from Front Vet Sci. 2022 Jun 21;9:906944 (via https://www.frontiersin.org/articles/10.3389/fvets.2022.9069)
During 2014-2016, clade 2.3.4.4 H5N8 high pathogenicity avian influenza virus (HPAIV) caused the largest known avian influenza epidemic in South Korea. Based on data from earlier H5N8 outbreaks, primitive ...

Tanikawa T, Fujii K, Sugie Y, Tsunekuni R, Nakayam. Comparative susceptibility of mallard (Anas platyrhynchos) to infection with high pathogenicity avian influenza virus strains (Gs/Gd lineage) isolated in Japan in 2004-2017. Vet Microbiol. 2022 Jun 28;272:109496.  Abstract  
submitted by kickingbird at Jul, 9, 2022 from Vet Microbiol. 2022 Jun 28;272:109496 (via https://www.sciencedirect.com/science/article/pii/S037811352)
The Goose/Guangdong-lineage (Gs/Gd) H5 high pathogenicity avian influenza viruses (HPAIVs) spread among poultry and wild birds worldwide; an association has been identified between the migration of wild ...

Si L, Shen Q, Li J, Chen L, Shen J, Xiao X, Bai H,. Generation of a live attenuated influenza A vaccine by proteolysis targeting. Nat Biotechnol. 2022 Jul 4.  Abstract  
submitted by kickingbird at Jul, 7, 2022 from Nat Biotechnol. 2022 Jul 4 (via https://www.nature.com/articles/s41587-022-01381-4)
The usefulness of live attenuated virus vaccines has been limited by suboptimal immunogenicity, safety concerns or cumbersome manufacturing processes and techniques. Here we describe the generation of ...

Kakuya F, Okubo H, Fujiyasu H, Kurisawa MJ, Kinebu. Clinical effectiveness of baloxavir marboxil against influenza in three seasons. Pediatr Int. 2022 Jan;64(1):e15169..  Abstract  
submitted by kickingbird at Jul, 7, 2022 from Pediatr Int. 2022 Jan;64(1):e15169. (via https://onlinelibrary.wiley.com/doi/10.1111/ped.15169)
Background: Previous reports have not clarified the difference in clinical efficacy between baloxavir and oseltamivir against influenza.Methods: A prospective observational study was performed during 2017-2018, ...

Jamoussi A, Ayed S, Merhabene T, Doghri H, Ben Khe. Severe influenza A in a Tunisian ICU sentinel SARI centre: Epidemiological and clinical features. PLoS One. 2022 Jul 6;17(7):e0270814..  Abstract  
submitted by kickingbird at Jul, 7, 2022 from PLoS One. 2022 Jul 6;17(7):e0270814. (via https://journals.plos.org/plosone/article?id=10.1371/journal)
Introduction: Influenza A virus infection is a contagious acute respiratory infection which mostly evolves in an epidemic form, less frequently as pandemic outbreaks. It can take a severe clinical form ...

Wang C, Qu R, Zong Y, Qin C, Liu L, Gao X, Sun H,. Enhanced stability of M1 protein mediated by a phospho-resistant mutation promotes the replication of prevailing avian influenza virus in mammals. PLoS Pathog. 2022 Jul 6;18(7):e1010645..  Abstract  
submitted by kickingbird at Jul, 7, 2022 from PLoS Pathog. 2022 Jul 6;18(7):e1010645. (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Avian influenza virus (AIV) can evolve multiple strategies to combat host antiviral defenses and establish efficient infectivity in mammals, including humans. H9N2 AIV and its reassortants (such as H5N6 ...

Ding L, Chen Y, Su N, Xu X, Yin J, Qiu J, Wang J,. Comparison of acute respiratory distress syndrome in patients with COVID-19 and influenza A (H7N9) virus infection. Int J Infect Dis. 2022 Jul 3:S1201-9712(22)00387-3.  Abstract  
submitted by kickingbird at Jul, 7, 2022 from Int J Infect Dis. 2022 Jul 3:S1201-9712(22)00387-3 (via https://www.ijidonline.com/article/S1201-9712(22)00387-3/ful)
Objectives: We aimed to compared the clinical features of acute respiratory distress syndrome (ARDS) induced by COVID-19 and H7N9 virus infections.Methods: Clinical data of 100 COVID-19 patients and 46 ...

Rattanaburi S, Sawaswong V, Nimsamer P, Mayuramart. Genome characterization and mutation analysis of human influenza A virus in Thailand. Genomics Inform. 2022 Jun;20(2):e21.  Abstract  
submitted by kickingbird at Jul, 7, 2022 from Genomics Inform. 2022 Jun;20(2):e21 (via https://genominfo.org/journal/view.php?doi=10.5808/gi.21077)
The influenza A viruses have high mutation rates and cause a serious health problem worldwide. Therefore, this study focused on genome characterization of the viruses isolated from Thai patients based ...

Wen F, Zhang X, Guo J, Liang Z, Cheng Q, Wang C, Y. Emergence of H3N8 avian influenza viruses possessing tri-basic hemagglutinin cleavage sites in China. J Infect. 2022 Jul 1:S0163-4453(22)00383-8.  Abstract  
submitted by kickingbird at Jul, 6, 2022 from J Infect. 2022 Jul 1:S0163-4453(22)00383-8 (via https://www.journalofinfection.com/article/S0163-4453(22)003)
Recently, the first human case of acute respiratory distress syndrome caused by the H3N8 subtype avian influenza virus (AIV) (A/Henan/4-10CNIC/2022, Henan4-10) was documented in this journal. The H3N8 ...

Niu X, Wang H, Zhao L, Lian P, Bai Y, Li J, Qiao J. All-trans retinoic acid increases the pathogenicity of the H9N2 influenza virus in mice. Virol J. 2022 Jun 28;19(1):113.  Abstract  
submitted by kickingbird at Jul, 1, 2022 from Virol J. 2022 Jun 28;19(1):113 (via https://virologyj.biomedcentral.com/articles/10.1186/s12985-)
Background: The H9N2 virus can infect not only birds but also humans. The pathogenicity of H9N2 virus infection is determined by an excessive immune response in the lung. All-trans retinoic acid (ATRA), ...

Neveau MN, Zeller MA, Kaplan BS, Souza CK, Gauger. Genetic and Antigenic Characterization of an Expanding H3 Influenza A Virus Clade in U.S. Swine Visualized by Nextstrain. mSphere. 2022 Jun 29;7(3):e0099421.  Abstract  
submitted by kickingbird at Jul, 1, 2022 from mSphere. 2022 Jun 29;7(3):e0099421 (via https://journals.asm.org/doi/10.1128/msphere.00994-21)
Defining factors that influence spatial and temporal patterns of influenza A virus (IAV) is essential to inform vaccine strain selection and strategies to reduce the spread of potentially zoonotic swine-origin ...

Subbiah J, Oh J, Kim KH, Shin CH, Park BR, Bhatnag. A chimeric thermostable M2e and H3 stalk-based universal influenza A virus vaccine. NPJ Vaccines. 2022 Jun 29;7(1):68.  Abstract  
submitted by kickingbird at Jul, 1, 2022 from NPJ Vaccines. 2022 Jun 29;7(1):68 (via https://www.nature.com/articles/s41541-022-00498-6)
We developed a new chimeric M2e and H3 hemagglutinin (HA) stalk protein vaccine (M2e-H3 stalk) by genetic engineering of modified H3 stalk domain conjugated with conserved M2e epitopes to overcome the ...

Huang WJ, Cheng YH, Tan MJ, Liu J, Li XY, Zeng XX,. Epidemiological and virological surveillance of influenza viruses in China during 2020-2021. Infect Dis Poverty. 2022 Jun 29;11(1):74.  Abstract  
submitted by kickingbird at Jul, 1, 2022 from Infect Dis Poverty. 2022 Jun 29;11(1):74 (via https://idpjournal.biomedcentral.com/articles/10.1186/s40249)
Background: During the coronavirus disease 2019 (COVID-19) pandemic, seasonal influenza activity declined globally and remained below previous seasonal levels, but intensified in China since 2021. Preventive ...

Sewald K, Danov O. Infection of Human Precision-Cut Lung Slices with the Influenza Virus. Methods Mol Biol. 2022;2506:119-134.  Abstract  
submitted by kickingbird at Jul, 1, 2022 from Methods Mol Biol. 2022;2506:119-134 (via https://link.springer.com/protocol/10.1007/978-1-0716-2364-0)
Viral infections are common causes of asthma exacerbations. To model these processes ex vivo, human precision-cut lung slices (PCLSs) can be used. Here we describe the infection of human PCLSs with the ...

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