Ruhl A, Ant?o AV, Dietschmann A, Radtke D, Tenbusc. STAT6-induced production of mucus and resistin-like molecules in lung Club cells does not protect against helminth or Influenza A virus infection. Eur J Immunol. 2023 Oct 19:e2350558. Abstract
submitted by kickingbird at Oct, 20, 2023 from Eur J Immunol. 2023 Oct 19:e2350558 (via https://onlinelibrary.wiley.com/doi/10.1002/eji.202350558)
Airway epithelial cells contribute to a variety of lung diseases including allergic asthma, where IL-4 and IL-13 promote activation of the transcription factor STAT6. This leads to goblet cell hyperplasia ... Lagan P, McKenna R, Baleed S, Hanna B, Barley J, M. Highly pathogenic avian influenza A(H5N1) virus infection in foxes with PB2-M535I identified as a novel mammalian adaptation, Northern Ireland, July 2023. Euro Surveill. 2023 Oct;28(42). Abstract
submitted by kickingbird at Oct, 20, 2023 from Euro Surveill. 2023 Oct;28(42) (via https://www.eurosurveillance.org/content/10.2807/1560-7917.E)
We report cases of mammalian infection with highly pathogenic avian influenza (HPAI) virus A(H5N1) clade 2.3.4.4b in Northern Ireland. Two common gulls (Larus canus) and two red fox kits (Vulpes vulpes), ... Liang Y, Hjulsager CK, Jensen TK, Hammer ASV, Oves. Characterization of high pathogenicity avian influenza H5Nx viruses from a wild harbor seal and red foxes in Denmark, 2021 and 2022. Influenza Other Respir Viruses. 2023 Oct 15;17(10). Abstract
submitted by kickingbird at Oct, 19, 2023 from Influenza Other Respir Viruses. 2023 Oct 15;17(10) (via https://onlinelibrary.wiley.com/doi/10.1111/irv.13208)
In 2021 and 2022, clade 2.3.4.4b H5Nx high pathogenicity avian influenza viruses were detected in one harbor seal and in one adult and three fox cubs in Denmark. The viruses were closely related to contemporary ... Kasmani MY, Topchyan P, Brown AK, Brown RJ, Wu X,. A spatial sequencing atlas of age-induced changes in the lung during influenza infection. Nat Commun. 2023 Oct 18;14(1):6597. Abstract
submitted by kickingbird at Oct, 19, 2023 from Nat Commun. 2023 Oct 18;14(1):6597 (via https://www.nature.com/articles/s41467-023-42021-y)
Influenza virus infection causes increased morbidity and mortality in the elderly. Aging impairs the immune response to influenza, both intrinsically and because of altered interactions with endothelial ... Xie R, Edwards KM, Wille M, Wei X, Wong SS, Zanin. The episodic resurgence of highly pathogenic avian influenza H5 virus. Nature. 2023 Oct 18. Abstract
submitted by kickingbird at Oct, 19, 2023 from Nature. 2023 Oct 18 (via https://www.nature.com/articles/s41586-023-06631-2)
Highly pathogenic avian influenza (HPAI) H5N1 activity has intensified globally since 2021, increasingly causing mass mortality in wild birds and poultry and incidental infections in mammals1-3. However, ... Gao J, Wei J, Qin S, Liu S, Mo S, Long Q, Tan S, L. Exploring the global immune landscape of peripheral blood mononuclear cells in H5N6-infected patient with single-cell transcriptomics. BMC Med Genomics. 2023 Oct 18;16(1):249. Abstract
submitted by kickingbird at Oct, 19, 2023 from BMC Med Genomics. 2023 Oct 18;16(1):249 (via https://bmcmedgenomics.biomedcentral.com/articles/10.1186/s1)
Background: Avian influenza viruses (AIV), particularly H5N6, have risen in infection frequency, prompting major concerns. Single-cell RNA sequencing (scRNA-seq) can illustrate the immune cell landscape ... Gaide N, Filaire F, Bertran K, Crispo M, Dirat M,. The Feather Epithelium Contributes to the Dissemination and Ecology of clade 2.3.4.4b H5 High Pathogenicity Avian Influenza Viruses in Ducks. Emerg Microbes Infect. 2023 Oct 17:2272644.. Abstract
submitted by kickingbird at Oct, 18, 2023 from Emerg Microbes Infect. 2023 Oct 17:2272644. (via https://www.tandfonline.com/doi/full/10.1080/22221751.2023.2)
Immature feathers are known replication sites for high pathogenicity avian influenza viruses (HPAIVs) in poultry. However, it is unclear whether feathers play an active role in viral transmission. This ... Yang L, Zhang T, Han X, Yang J, Sun Y, Ma L, Chen. Influenza Epidemic Trend Surveillance and Prediction Based on Search Engine Data: Deep Learning Model Study. J Med Internet Res. 2023 Oct 17;25:e45085. Abstract
submitted by kickingbird at Oct, 18, 2023 from J Med Internet Res. 2023 Oct 17;25:e45085 (via https://www.jmir.org/2023/1/e45085)
Background: Influenza outbreaks pose a significant threat to global public health. Traditional surveillance systems and simple algorithms often struggle to predict influenza outbreaks in an accurate and ... Liang CY, Huang I, Han J, Sownthirarajan B, Kulhan. Avian influenza A viruses exhibit plasticity in sialylglycoconjugate receptor usage in human lung cells. J Virol. 2023 Oct 16:e0090623. Abstract
submitted by kickingbird at Oct, 17, 2023 from J Virol. 2023 Oct 16:e0090623 (via https://journals.asm.org/doi/10.1128/jvi.00906-23)
Influenza A viruses (IAV) utilize sialic acid (Sia) containing cell surface glycoconjugates for host cell infection, and IAV strains from different host species show preferences for structurally distinct ... Li M, Wang W, Chen J, Zhan Z, Xu M, Liu N, Ren L,. Transplacental transfer efficiency of maternal antibodies against influenza A(H1N1)pdm09 virus and dynamics of naturally acquired antibodies in Chinese children: a longitudinal, paired mother-neonate. Lancet Microbe. 2023 Oct 9:S2666-5247(23)00181-7. Abstract
submitted by kickingbird at Oct, 16, 2023 from Lancet Microbe. 2023 Oct 9:S2666-5247(23)00181-7 (via https://www.thelancet.com/journals/lanmic/article/PIIS2666-5)
Background: The 2009 pandemic H1N1 influenza A virus (A(H1N1)pdm09 virus) evolves rapidly and has continued to cause severe infections in children since its emergence in 2009. We aimed to characterise ... White EB, O´Halloran A, Sundaresan D, Gilmer. High Influenza Incidence and Disease Severity Among Children and Adolescents Aged <18 Years - United States, 2022-23 Season. MMWR Morb Mortal Wkly Rep. 2023 Oct 13;72(41):1108. Abstract
submitted by kickingbird at Oct, 16, 2023 from MMWR Morb Mortal Wkly Rep. 2023 Oct 13;72(41):1108 (via https://www.cdc.gov/mmwr/volumes/72/wr/mm7241a2.htm?s_cid=mm)
During the 2022-23 influenza season, early increases in influenza activity, co-circulation of influenza with other respiratory viruses, and high influenza-associated hospitalization rates, particularly ... Cui P, Shi J, Yan C, Wang C, Zhang Y, Zhang Y, Xin. Analysis of avian influenza A (H3N8) viruses in poultry and their zoonotic potential, China, September 2021 to May 2022. Euro Surveill. 2023 Oct;28(41):2200871. Abstract
submitted by kickingbird at Oct, 16, 2023 from Euro Surveill. 2023 Oct;28(41):2200871 (via https://www.eurosurveillance.org/content/10.2807/1560-7917.E)
BackgroundTwo human cases of avian influenza A (H3N8) virus infection were reported in China in 2022.AimTo characterise H3N8 viruses circulating in China in September 2021-May 2022.MethodsWe sampled poultry ... Khan Y, Kassymbekov Y, Suleimenova S, Karamendin K. Genome sequence of equine influenza virus isolated from horses in southeast Kazakhstan in 2020. Microbiol Resour Announc. 2023 Oct 12:e0043323. Abstract
submitted by kickingbird at Oct, 16, 2023 from Microbiol Resour Announc. 2023 Oct 12:e0043323 (via https://journals.asm.org/doi/10.1128/mra.00433-23)
An influenza virus strain, A/equine/Almaty/268/2020, was isolated from horses in southeast Kazakhstan in 2020. Here, we present the nearly complete genome sequence of this epidemic strain. This study was ... Pleros C, Adamidis K, Kantartzi K, Griveas I, Balt. Dialysis Patients Respond Adequately to Influenza Vaccination Irrespective of Dialysis Modality and Chronic Inflammation. J Clin Med. 2023 Sep 26;12(19):6205. Abstract
submitted by kickingbird at Oct, 16, 2023 from J Clin Med. 2023 Sep 26;12(19):6205 (via https://www.mdpi.com/2077-0383/12/19/6205)
(1) Background: Chronic inflammation and suboptimal immune responses to vaccinations are considered to be aspects of immune dysregulation in patients that are undergoing dialysis. The present study aimed ... Dai M, Zhu S, An Z, You B, Li Z, Yao Y, Nair V, Li. Dissection of key factors correlating with H5N1 avian influenza virus driven inflammatory lung injury of chicken identified by single-cell analysis. PLoS Pathog. 2023 Oct 11;19(10):e1011685. Abstract
submitted by kickingbird at Oct, 12, 2023 from PLoS Pathog. 2023 Oct 11;19(10):e1011685 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Chicken lung is an important target organ of avian influenza virus (AIV) infection, and different pathogenic virus strains lead to opposite prognosis. Using a single-cell RNA sequencing (scRNA-seq) assay, ... Diefenbach-Elstob TR, Chanthalavanh P, Bobbitt ME,. Report on influenza viruses received and tested by the Melbourne WHO Collaborating Centre for Reference and Research on Influenza during 2022. Commun Dis Intell (2018). 2023 Jul 27;47. Abstract
submitted by kickingbird at Oct, 12, 2023 from Commun Dis Intell (2018). 2023 Jul 27;47 (via https://www1.health.gov.au/internet/main/publishing.nsf/Cont)
As part of its role in the World Health Organization's (WHO) Global Influenza Surveillance and Response System (GISRS), the WHO Collaborating Centre for Reference and Research on Influenza in Melbourne ... Sheppard CM, Goldhill DH, Swann OC, Staller E, Pen. An Influenza A virus can evolve to use human ANP32E through altering polymerase dimerization. Nat Commun. 2023 Oct 10;14(1):6135. Abstract
submitted by kickingbird at Oct, 12, 2023 from Nat Commun. 2023 Oct 10;14(1):6135 (via https://www.nature.com/articles/s41467-023-41308-4)
Human ANP32A and ANP32B are essential but redundant host factors for influenza virus genome replication. While most influenza viruses cannot replicate in edited human cells lacking both ANP32A and ANP32B, ... Idoko-Akoh A, Goldhill DH, Sheppard CM, Bialy D, Q. Creating resistance to avian influenza infection through genome editing of the ANP32 gene family. Nat Commun. 2023 Oct 10;14(1):6136. Abstract
submitted by kickingbird at Oct, 12, 2023 from Nat Commun. 2023 Oct 10;14(1):6136 (via https://www.nature.com/articles/s41467-023-41476-3)
Chickens genetically resistant to avian influenza could prevent future outbreaks. In chickens, influenza A virus (IAV) relies on host protein ANP32A. Here we use CRISPR/Cas9 to generate homozygous gene ... Li Y, Shang J, Wang Y, Luo J, Jiang W, Yin X, Zhan. Establishment of two assays based on reverse transcription recombinase-aided amplification technology for rapid detection of H5 subtype avian influenza virus. Microbiol Spectr. 2023 Oct 9:e0218623. Abstract
submitted by kickingbird at Oct, 12, 2023 from Microbiol Spectr. 2023 Oct 9:e0218623 (via https://journals.asm.org/doi/10.1128/spectrum.02186-23)
The avian influenza virus (AIV), a member of the type A influenza virus group, is harbored by avian hosts. The highly pathogenic H5 subtype of AIV has inflicted significant financial damage on the poultry ... European Food Safety Authority; European Centre fo. Avian influenza overview June-September 2023. EFSA J. 2023 Oct 5;21(10):e08328. Abstract
submitted by kickingbird at Oct, 12, 2023 from EFSA J. 2023 Oct 5;21(10):e08328 (via https://efsa.onlinelibrary.wiley.com/doi/abs/10.2903/j.efsa.)
Between 24 June and 1 September 2023, highly pathogenic avian influenza (HPAI) A(H5) outbreaks were reported in domestic (25) and wild (482) birds across 21 countries in Europe. Most of these outbreaks ... 8128 items, 20/Page, Page[53/407][|<<] [|<] [51] [52] [53] [54] [55] [56] [57] [58] [59] [60] [>|] [>>|] |
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