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2026-4-18 17:04:02
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Matthys A, Amelinck L, Smet A, Ysenbaert T, Vogel. Internal gene segments from a mouse-adapted influenza B virus confer increased pathogenicity to mice. PLoS One. 2026 Mar 23;21(3):e0335324.  Abstract  
submitted by kickingbird at Mar, 24, 2026 from PLoS One. 2026 Mar 23;21(3):e0335324 (via https://journals.plos.org/plosone/article?id=10.1371/journal)
Influenza B viruses (IBVs) contribute significantly to the annual influenza epidemics in human. Most IBV strains are non- or poorly pathogenic in mice, which are frequently used for vaccine studies. We ...

Jenny J Ahn, Timothy C Yu, Bernadeta Dadonaite, Ca. Influenza hemagglutinin subtypes have different sequence constraints despite sharing extremely similar structures. Virus Evolution, 2026;, veag018.  Abstract  
submitted by kickingbird at Mar, 22, 2026 from Virus Evolution, 2026;, veag018 (via https://academic.oup.com/ve/advance-article/doi/10.1093/ve/v)
Hemagglutinins (HA) from different influenza A virus subtypes share as little as ~40% amino acid identity, yet their protein structure and cell entry function are highly conserved. Here we examine the ...

Augustin Clessin, etc.,al. [preprint]Dispersal, adaptation and persistence of H5N1 in the sub-Antarctic and Antarctica. https://doi.org/10.64898/2026.03.20.713283.  Abstract  
submitted by kickingbird at Mar, 22, 2026 from https://doi.org/10.64898/2026.03.20.713283 (via https://www.biorxiv.org/content/10.64898/2026.03.20.713283v1)
High pathogenicity avian influenza virus (HPAIV) H5N1 reached the sub-Antarctic and Antarctica in 2023, subsequently spreading to remote locations within this region where it had devastating impacts on ...

Qiqi Yang, etc.,al. [preprint]Dynamics and control of highly pathogenic H5 avian influenza in a threatened pelican population. https://doi.org/10.64898/2026.03.16.712014.  Abstract  
submitted by kickingbird at Mar, 21, 2026 from https://doi.org/10.64898/2026.03.16.712014 (via https://www.biorxiv.org/content/10.64898/2026.03.16.712014v1)
The ongoing epizootic of highly pathogenic avian influenza (HPAI) continues to cause massive deaths in wildlife. Fundamental understanding of its disease ecology in natural populations is urgently needed. ...

Ali, M.Z., Edet, U.O., Salauddin, M. et al. Two decades (2005 to 2025) of avian influenza research trends, knowledge gaps and distribution of emerging H5N1 2.3.4.4b clade in South Asia. One Health Outlook (2026).  Abstract  
submitted by kickingbird at Mar, 20, 2026 from One Health Outlook (2026) (via https://link.springer.com/article/10.1186/s42522-026-00206-7)
Avian influenza virus (AIV) remains a persistent zoonotic and economic threat in South Asia, yet a comprehensive understanding of its research trajectory, outbreak patterns, and viral evolution in the ...

Rosa C van Hoorn, etc.,al. [preprint]Behavioural determinants of testing behaviour during a hypothetical avian influenza outbreak: an interview study. https://doi.org/10.64898/2026.03.17.26348610.  Abstract  
submitted by kickingbird at Mar, 20, 2026 from https://doi.org/10.64898/2026.03.17.26348610 (via https://www.medrxiv.org/content/10.64898/2026.03.17.26348610)
Background: Avian Influenza (AI) is a potential pandemic threat, specifically when human-to-human transmission occurs. For outbreak management testing is essential. Current knowledge on testing behaviour ...

Cui P, Zhou S, Chard AN, Wang J, Tan KR, Song Y, P. Northern Hemisphere 2025/26 influenza vaccine effectiveness during months with influenza A(H3N2) subclade K predominance - Suzhou, Eastern China. International Journal of Infectious Diseases, 2026.  Abstract  
submitted by kickingbird at Mar, 19, 2026 from International Journal of Infectious Diseases, 2026 (via https://www.ijidonline.com/article/S1201-9712(26)00187-6/ful)
During this 2025/26 Northern Hemisphere influenza season, the predominant influenza A(H3N2) subclade K virus has binding site mutations and postvaccine sera reduced inhibition, raising concerns about antigenic ...

Chen D, Zhao G, Zhou J, Sun P, He S, Lv C, Chen Y,. Delactylation of viral proteins by SIRT1 suppresses influenza A virus replication. mBio. 2026 Mar 18:e0248925.  Abstract  
submitted by kickingbird at Mar, 19, 2026 from mBio. 2026 Mar 18:e0248925 (via https://journals.asm.org/doi/10.1128/mbio.02489-25)
Lactylation, a protein post-translational modification driven by lactate, plays crucial roles in various physiological and pathological processes. However, the function and underlying mechanisms of lactylation ...

EFSA (European Food Safety Authority), Smith AIM,. Risk communication on avian flu biosecurity: social research, audience segmentation, and communication strategy for an EU awareness-raising campaign. EFSA supporting publication 2026:23(3).  Abstract  
submitted by kickingbird at Mar, 19, 2026 from EFSA supporting publication 2026:23(3) (via https://efsa.onlinelibrary.wiley.com/doi/10.2903/sp.efsa.202)
This report comprises EFSA's response to the European Commission's request for technical assistance in risk communication for a strengthened, evidence-based approach to awareness-raising on avian influenza ...

J.Charostad, Z.-a.Ghoreshi, N.Arefinia, et al. Aptamer-Based Approaches for Influenza Virus Detection: A Systematic Review. Health Science Reports9 (2026): e72118.  Abstract  
submitted by kickingbird at Mar, 19, 2026 from Health Science Reports9 (2026): e72118 (via https://onlinelibrary.wiley.com/doi/10.1002/hsr2.72118)
Background and AimsInfluenza remains a globally prevalent respiratory infection that is challenging to diagnose accurately. This systematic review focuses on aptamer-based tools for influenza virus detection, ...

D. U.Nnaji, O.Chinenye, G. C.Nnaji, S. O.John, and. Modeling Airborne Influenza in Three Dimensions. Engineering Reports8, no. 3 (2026): e70661.  Abstract  
submitted by kickingbird at Mar, 16, 2026 from Engineering Reports8, no. 3 (2026): e70661 (via https://onlinelibrary.wiley.com/doi/10.1002/eng2.70661)
Spatial differences in how people live and move are key to understanding how flu spreads, but many traditional models ignore these details, making it harder to predict real-world outbreaks. In this study, ...

Koolaparambil Mukesh, R., Kaiser, F.K., Schulz, J.. Increased contact transmission of contemporary Human H5N1 compared to Bovine and Mountain Lion H5N1 in a hamster model. Nat Commun (2026).  Abstract  
submitted by kickingbird at Mar, 16, 2026 from Nat Commun (2026) (via https://link.springer.com/article/10.1038/s41467-026-68900-8)
The ongoing outbreak of highly pathogenic avian influenza virus (HPAIV) subtype H5N1 in the U.S. poses a significant public health threat. To date, 70 human cases have been confirmed in the United States, ...

Septer KM, Sim DG, Patel DR, Field CJ, Wang W, Rod. Immunity to hemagglutinin and neuraminidase results in additive reductions in airborne transmission of influenza H1N1 virus in ferrets. Sci Adv. 2026 Mar 13;12(11):eaea8719.  Abstract  
submitted by kickingbird at Mar, 16, 2026 from Sci Adv. 2026 Mar 13;12(11):eaea8719 (via https://www.science.org/doi/10.1126/sciadv.aea8719)
Currently, there is limited knowledge on the impact of immunity to hemagglutinin (HA) and/or neuraminidase (NA) on the transmission of influenza viruses. Therefore, using intramuscular vaccination, intranasal ...

Liu Y, Boklund AE, Kj?r LJ, Liang Y, Mortensen S,. A modelling exploration of potential spatiotemporal risk of high pathogenicity avian influenza virus introduction to Danish dairy herds through the contaminated environment. Res Vet Sci. 2026 Mar 10;204:106144.  Abstract  
submitted by kickingbird at Mar, 16, 2026 from Res Vet Sci. 2026 Mar 10;204:106144 (via https://www.sciencedirect.com/science/article/pii/S003452882)
Circulation of high pathogenicity avian influenza virus (HPAIV) among cattle in the US as a result from spillover events from wild birds has been reported since 2024. The consequences have reduced animal ...

Yang Y, Liu H, Li Y, Liu L, Chen T, Zhang J. Emergence of a novel H4N6 avian influenza virus with mammalian adaptation isolated from migratory birds in Zhejiang Province, China, 2024. Virol Sin. 2026 Mar 13:S1995-820X(26)00042-8.  Abstract  
submitted by kickingbird at Mar, 16, 2026 from Virol Sin. 2026 Mar 13:S1995-820X(26)00042-8 (via https://www.sciencedirect.com/science/article/pii/S1995820X2)
HIGHLIGHTS:The H4N6/G030 strain, a novel H4N6 avian influenza virus (AIV), was isolated from a red-necked stint.The H4N6/G030 is a novel cross-species reassortant derived from wild bird and poultry AIV ...

WPRO. Avian Influenza Weekly Update # 1037: 13 March 2026. WHO.  Abstract  
submitted by kickingbird at Mar, 16, 2026 from WHO (via https://www.who.int/westernpacific/publications/m/item/avian)
Avian influenza subtype A(HxNy) normally spreads in birds but can also infect humans. Human infections are primarily acquired through direct contact with infected poultry or contaminated environments. ...

L?wa A, Budt M, Balázs A, Sikora V, Melzer M, Rubi. Clade 2.3.4.4b H5N1 influenza A virus exhibits high infectivity in human respiratory tract models. J Infect. 2026 Mar 12:106722.  Abstract  
submitted by kickingbird at Mar, 16, 2026 from J Infect. 2026 Mar 12:106722 (via https://www.journalofinfection.com/article/S0163-4453(26)000)
We read with great interest the recent letter by Li and colleagues reporting the emergence of mammalian-adapted clade 2.3.4.4b H5N1 viruses carrying the PB2-E627K mutation in migratory birds at Qinghai ...

Yang ST, Li XX, Luo WR, Hu MH, Zhou X, Yu JL, Fang. Phylogenetic Patterns and Spatiotemporal Evolution of H1N1pdm09 in Anhui Province, China, 2009-2023. Travel Med Infect Dis. 2026 Mar 12:102965.  Abstract  
submitted by kickingbird at Mar, 16, 2026 from Travel Med Infect Dis. 2026 Mar 12:102965 (via https://www.sciencedirect.com/science/article/pii/S147789392)
Background: No studies have deeply examined the phylogenetic patterns and spatiotemporal spread of H1N1pdm09 in Anhui Province, China.Methods: We conducted a genome-wide analysis of 162 historical epidemic ...

Coombes HA, Terrey J, Schlachter AL, McCarter P, R. Infection of ratites with clade 2.3.4.4b HPAIV H5N1: Potential implications for zoonotic risk. Emerg Microbes Infect. 2026 Mar 13:2645853.  Abstract  
submitted by kickingbird at Mar, 15, 2026 from Emerg Microbes Infect. 2026 Mar 13:2645853 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2026.2)
We detected H5N1 high pathogenicity avian influenza in captive Greater Rhea (Rhea americana). Viral genetic analysis revealed the mammalian associated PB2-E627 K mutation, indicating selection of mammalian-relevant ...

Kandeil A, Chopra P, Ray SD, Ghotekar BK, Ranadhee. Receptor-binding specificity and antigenic properties of a genotype D1.1 A(H5N1) influenza virus isolated from a human. Emerg Microbes Infect. 2026 Mar 13:2645856.  Abstract  
submitted by kickingbird at Mar, 15, 2026 from Emerg Microbes Infect. 2026 Mar 13:2645856 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2026.2)
Clade 2.3.4.4b A(H5N1) influenza viruses continue to expand their host range and pose increasing public health concerns. A case of severe human infection with genotype D1.1 A(H5N1) with Hà substitutions ...

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