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2024-11-23 8:43:09
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Bialy D, Richardson S, Chrzastek K, Bhat S, Polo N. Recombinant A(H6N1)-H274Y avian influenza virus with dual drug resistance does not require permissive mutations to retain the replicative fitness in vitro and in ovo. Virology. 2023 Dec 2;590:109954.  Abstract  
submitted by kickingbird at Dec, 14, 2023 from Virology. 2023 Dec 2;590:109954 (via https://www.sciencedirect.com/science/article/pii/S004268222)
The possible emergence of drug-resistant avian flu raises concerns over the limited effectiveness of currently approved antivirals (neuraminidase inhibitors - NAIs) in the hypothetical event of a zoonotic ...

Zhou X, Lin Z, Tu J, Zhu C, Li H. Persistent predominance of the Victoria lineage of influenza B virus during COVID-19 epidemic in Nanchang, China. Influenza Other Respir Viruses. 2023 Dec 10;17(12).  Abstract  
submitted by kickingbird at Dec, 14, 2023 from Influenza Other Respir Viruses. 2023 Dec 10;17(12) (via https://onlinelibrary.wiley.com/doi/10.1111/irv.13226)
he sentinel hospital-based influenza-like illness (ILI) surveillance network was established in China since the 2009 H1N1 pandemic. This network plays important roles in monitoring influenza virus variation ...

Trov?o NS, Khan SM, Lemey P, Nelson MI, Cherry JL. Comparative evolution of influenza A virus H1 and H3 head and stalk domains across host species. mBio. 2023 Dec 11:e0264923.  Abstract  
submitted by kickingbird at Dec, 12, 2023 from mBio. 2023 Dec 11:e0264923 (via https://journals.asm.org/doi/10.1128/mbio.02649-23)
For decades, researchers have studied the rapid evolution of influenza A viruses for vaccine design and as a useful model system for the study of host/parasite evolution. By performing an exhaustive analysis ...

Guan W, Qu R, Shen L, Mai K, Pan W, Lin Z, Chen L,. Baloxavir marboxil use for critical human infection of avian influenza A H5N6 virus. Med. 2023 Dec 5:S2666-6340(23)00361-6.  Abstract  
submitted by kickingbird at Dec, 11, 2023 from Med. 2023 Dec 5:S2666-6340(23)00361-6 (via https://www.cell.com/med/fulltext/S2666-6340(23)00361-6)
Background: Recent outbreaks of avian influenza and ongoing virus reassortment have drawn focus on spill-over infections. The increase in human infections with highly pathogenic avian influenza H5N6 virus ...

Lijuan Liang, etc.,al. Genetic variation and evolution of influenza viruses isolated from co-infection cases in Guangdong Province. DOI: 10.3760/cma.j.cn112309-20230717-00213.  Abstract  
submitted by kickingbird at Dec, 11, 2023 from DOI: 10.3760/cma.j.cn112309-20230717-00213 (via https://rs.yiigle.com/cmaid/1482234)
Objective To analyze and reveal the genetic evolution and variation of influenza viruses in cases of co-infection in Guangdong Province.Methods Throat swab samples were collected from four cases of H1N1pdm ...

Ly H. Highly pathogenic avian influenza H5N1 virus infection of companion animals. Virulence. 2024 Dec;15(1):2289780.  Abstract  
submitted by kickingbird at Dec, 10, 2023 from Virulence. 2024 Dec;15(1):2289780 (via https://www.tandfonline.com/doi/full/10.1080/21505594.2023.2)
While it is known that influenza viruses can frequently infect a variety of animal species, including humans (for a review, see ref., it is relatively uncommon for companion animals (e.g. pet cats and ...

Wang X, Zheng H, Gao R, Ren L, Jin M, Ji Z, Wang X. Genetically Related Avian Influenza H7N9 Viruses Exhibit Different Pathogenicity in Mice. Animals (Basel). 2023 Nov 28;13(23):3680.  Abstract  
submitted by kickingbird at Dec, 10, 2023 from Animals (Basel). 2023 Nov 28;13(23):3680 (via https://www.mdpi.com/2076-2615/13/23/3680)
Avian influenza viruses can cross species barriers and adapt to mammals. The H7N9 subtype AIV that emerged in China in 2013 caused 1568 human infections, with a mortality rate of nearly 40%. We conducted ...

Xianying Zeng, Guobin Tian, Hualan Chen. Progress in development and application of H5/H7 avian influenza vaccines in China. SCIENTIA SINICA Vitae.  Abstract  
submitted by kickingbird at Dec, 9, 2023 from SCIENTIA SINICA Vitae (via doi:10.1360/SSV-2023-0144)
Since 1959,H5/H7 subtype avian influenza viruses(AIVs)have continued to endanger the development of the poultry industry and public health.In order to effectively control the H5/H7 subtype AIVs in poultry,China ...

Zhao W, Liu X, Zhang X, Qiu Z, Jiao J, Li Y, Gao R. Virulence and transmission characteristics of clade 2.3.4.4b H5N6 subtype avian influenza viruses possessing different internal gene constellations. Virulence. 2023 Dec;14(1):2250065.  Abstract  
submitted by kickingbird at Dec, 9, 2023 from Virulence. 2023 Dec;14(1):2250065 (via https://www.tandfonline.com/doi/full/10.1080/21505594.2023.2)
Clade 2.3.4.4 H5N6 avian influenza virus (AIV) has been predominant in poultry in China, and the circulating haemagglutinin (HA) gene has changed from clade 2.3.4.4h to clade 2.3.4.4b in recent years. ...

Caceres CJ, Gay LC, Faccin FC, Pérez DR. Use of Reverse Genetics for the Generation of Recombinant Influenza Viruses Carrying Nanoluciferase. Methods Mol Biol. 2024;2733:47-74.  Abstract  
submitted by kickingbird at Dec, 9, 2023 from Methods Mol Biol. 2024;2733:47-74 (via https://link.springer.com/protocol/10.1007/978-1-0716-3533-9)
Influenza A (FLUAV) and influenza B (FLUBV) viruses are human and/or animal pathogens widely studied due to their importance to public health and animal production. Both FLUAV and FLUBV possess a genome ...

Kessler S, García-Sastre A, Schwemmle M, Ciminski. Reverse Genetics of Bat Influenza A Viruses. Methods Mol Biol. 2024;2733:75-86.  Abstract  
submitted by kickingbird at Dec, 9, 2023 from Methods Mol Biol. 2024;2733:75-86 (via https://link.springer.com/protocol/10.1007/978-1-0716-3533-9)
New World fruit bats were recently found to harbor two distinct and previously unknown influenza A viruses (IAVs) of the subtypes H17N10 and H18N11. Although viral genome sequences were detected in the ...

Renaud C, Osborn A, Parmley EJ, F Hatchette T, LeB. Highly pathogenic avian influenza: Unprecedented outbreaks in Canadian wildlife and domestic poultry. J Assoc Med Microbiol Infect Dis Can. 2023 Nov 29;.  Abstract  
submitted by kickingbird at Dec, 8, 2023 from J Assoc Med Microbiol Infect Dis Can. 2023 Nov 29; (via https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10697099/)
Canada experienced a wave of HPAI H5N1 outbreaks in the spring of 2022 with millions of wild and farmed birds being infected. Seabird mortalities in Canada have been particularly severe on the Atlantic ...

Zhang L, Shao Y, Wang Y, Yang Q, Guo J, Gao GF, De. Twenty natural amino acid substitution screening at the last residue 121 of influenza A virus NS2 protein reveals the critical role of NS2 in promoting virus genome replication by coordinating with vi. J Virol. 2023 Dec 6:e0116623.  Abstract  
submitted by kickingbird at Dec, 7, 2023 from J Virol. 2023 Dec 6:e0116623 (via https://journals.asm.org/doi/10.1128/jvi.01166-23)
The intrinsic mechanisms of influenza RNA polymerase (FluPol) in catalyzing viral genome transcription and replication have been largely resolved. However, the mechanisms of how transcription and replication ...

Minghong Zhang, etc.,al. Analysis on occupational exposure crowds and the environment of avian influenza in Nanchong, 2014-2015. DOI: 10.3760/cma.j.issn.1007-1245.2017.04.053.  Abstract  
submitted by kickingbird at Dec, 6, 2023 from DOI: 10.3760/cma.j.issn.1007-1245.2017.04.053 (via https://rs.yiigle.com/cmaid/991504)
Objective To investgate the infection of H5N1 avian influenza virus in occupational exposure crowds and the avian influenza virus distribution in the environment of Nanchong City.Methods The serum samples ...

Lee K, Yeom M, Hang Vu TT, Do HQ, Na W, Lee M, Jeo. Characterization of Highly Pathogenic Avian Influenza A (H5N1) Viruses isolated from Cats in South Korea, 2023. Emerg Microbes Infect. 2023 Dec 4:2290835.  Abstract  
submitted by kickingbird at Dec, 5, 2023 from Emerg Microbes Infect. 2023 Dec 4:2290835 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2023.2)
Influenza A viruses have frequently crossed species barriers and continually pose a threat to the health of birds, mammals, and humans. Highly pathogenic avian influenza virus (HPAIV), distinguished from ...

Zhou P, Qiu T, Wang X, Yang X, Shi H, Zhu C, Dai W. One HA stalk topping multiple heads as a novel influenza vaccine. Emerg Microbes Infect. 2023 Dec 4:2290838.  Abstract  
submitted by kickingbird at Dec, 5, 2023 from Emerg Microbes Infect. 2023 Dec 4:2290838 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2023.2)
Classic chimeric hemagglutinin (cHA) was designed to induce immune responses against the conserved stalk domain of HA. However, it is unclear whether combining more than one HA head domain onto one stalk ...

Tenforde MW, Weber ZA, Yang DH, DeSilva MB, Dascom. Influenza vaccine effectiveness against influenza-A-associated emergency department, urgent care, and hospitalization encounters among U.S. adults, 2022-2023. J Infect Dis. 2023 Dec 2:jiad542..  Abstract  
submitted by kickingbird at Dec, 3, 2023 from J Infect Dis. 2023 Dec 2:jiad542. (via https://academic.oup.com/jid/advance-article/doi/10.1093/inf)
Background: The 2022-2023 United States influenza season had unusually early influenza activity with high hospitalization rates. Vaccine-matched A(H3N2) viruses predominated, with lower levels of A(H1N1)pdm09 ...

Caliendo V, Kleyheeg E, Beerens N, Camphuysen KCJ,. Effect of 2020-21 and 2021-22 Highly Pathogenic Avian Influenza H5 Epidemics on Wild Birds, the Netherlands. Emerg Infect Dis. 2023 Dec 1;30(1).  Abstract  
submitted by kickingbird at Dec, 3, 2023 from Emerg Infect Dis. 2023 Dec 1;30(1) (via https://wwwnc.cdc.gov/eid/article/30/1/23-0970_article)
The number of highly pathogenic avian influenza (HPAI) H5-related infections and deaths of wild birds in Europe was high during October 1, 2020-September 30, 2022. To quantify deaths among wild species ...

Chua SCJH, Cui J, Sachaphibulkij K, Tan ISL, Tan H. The ER-Golgi transport of influenza virus through NS1-Sec13 association during virus replication. Microbiol Spectr. 2023 Dec 1:e0260923.  Abstract  
submitted by kickingbird at Dec, 2, 2023 from Microbiol Spectr. 2023 Dec 1:e0260923 (via https://journals.asm.org/doi/10.1128/spectrum.02609-23)
Influenza A virus is a respiratory virus that can cause complications such as acute bronchitis and secondary bacterial pneumonia. Drug therapies and vaccines are available against influenza, albeit limited ...

Hu Y, Jiang L, Wang G, Song Y, Shan Z, Wang X, Den. M6PR interacts with the HA2 subunit of influenza A virus to facilitate the fusion of viral and endosomal membranes. Sci China Life Sci. 2023 Nov 22.  Abstract  
submitted by kickingbird at Dec, 2, 2023 from Sci China Life Sci. 2023 Nov 22 (via https://link.springer.com/article/10.1007/s11427-023-2471-4)
Influenza A virus (IAV) commandeers numerous host cellular factors for successful replication. However, very few host factors have been revealed to be involved in the fusion of viral envelope and late ...

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