Planz O.. Development of cellular signaling pathway inhibitors as new antivirals against influenza. Antiviral Res. 2013 Apr 16. Abstract
submitted by kickingbird at Apr, 29, 2013 from Antiviral Res. 2013 Apr 16 (via http://www.ncbi.nlm.nih.gov/pubmed/23603495)
Influenza virus exploits a number of cellular signaling pathways during the course of its replication, rendering them potential targets for new therapeutic interventions. Several preclinical approaches ... Daniel A Salmon, etc.,al. Association between Guillain-Barré syndrome and influenza A (H1N1) 2009 monovalent inactivated vaccines in the USA: a meta-analysis. The Lancet, Volume 381, Issue 9876. Abstract
submitted by kickingbird at Apr, 28, 2013 from The Lancet, Volume 381, Issue 9876 (via http://www.thelancet.com/journals/lancet/article/PIIS0140-67)
Background
The influenza A (H1N1) 2009 monovalent vaccination programme was the largest mass vaccination initiative in recent US history. Commensurate with the size and scope of the vaccination programme, ... Skowronski DM, Janjua NZ, Kwindt TL, De Serres G. Virus-host interactions and the unusual age and sex distribution of human cases of influenza A(H7N9) in China, April 2013. Euro Surveill. 2013;18(17):pii=20465. Full Text
submitted by kickingbird at Apr, 26, 2013 from Euro Surveill. 2013;18(17):pii=20465 (via http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=2)
To the editor: Over the past two weeks, Eurosurveillance has published several timely papers related to the emergence of a new influenza A(H7N9) virus affecting humans in China [1-3]. Genetic studies by ... Corman VM, Eickmann M, Landt O, Bleicker T, Brünin. Specific detection by real-time reverse-transcription PCR assays of a novel avian influenza A(H7N9) strain associated with human spillover infections in China. Euro Surveill. 2013;18(16):pii=20461. Full Text
submitted by kickingbird at Apr, 26, 2013 from Euro Surveill. 2013;18(16):pii=20461 (via http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=2)
Background
An avian influenza A(H7N9) virus has emerged in south eastern China in March 2013 [1]. As of 16 April 2013, the Chinese authorities have reported 63 laboratory-confirmed human cases, 14 of ... Li Q, Zhou L, Zhou M, etc., al.. Preliminary Report: Epidemiology of the Avian Influenza A (H7N9) Outbreak in China. N Engl J Med 2013 Apr 24. Abstract
submitted by kickingbird at Apr, 26, 2013 from N Engl J Med 2013 Apr 24 (via http://www.nejm.org/doi/full/10.1056/NEJMoa1304617#Top)
Background
The first identified cases of avian influenza A (H7N9) virus infection in humans occurred in China during February and March 2013. We analyzed data obtained from field investigations to characterize ... Y Chen, etc.,al. Human infections with the emerging avian influenza A H7N9 virus from wet market poultry: clinical analysis and characterisation of viral genome. The Lancet,25 April 2013. Abstract
submitted by kickingbird at Apr, 26, 2013 from The Lancet,25 April 2013 (via http://www.lancet.com/journals/lancet/article/PIIS0140-6736()
Background
Human infection with avian influenza A H7N9 virus emerged in eastern China in February, 2013, and has been associated with exposure to poultry. We report the clinical and microbiological ... Y Arima, R Zu, M Murhekar, S Vong. Human infections with avian influenza A(H7N9) virus in China: preliminary assessments of the age and sex distribution. Western Pacific Surveillance and Response Journal,. Full Text
submitted by kickingbird at Apr, 24, 2013 from Western Pacific Surveillance and Response Journal, (via http://www.wpro.who.int/wpsar/volumes/04/2/2013_PE_EMT_Arima)
Since 31 March 2013, the government of China has been notifying the World Health Organization (WHO) of human infections with the avian influenza A(H7N9) virus,1 as mandated by the International Health ... Uyeki TM, Cox NJ.. Global Concerns Regarding Novel Influenza A (H7N9) Virus Infections. N Engl J Med. 2013 Apr 11. Full Text
submitted by kickingbird at Apr, 21, 2013 from N Engl J Med. 2013 Apr 11 (via http://www.nejm.org/doi/full/10.1056/NEJMp1304661)
Severe disease in humans caused by a novel influenza A virus that is distinct from circulating human influenza A viruses is a seminal event. It might herald sporadic human infections from an animal source ... ZHANG Y, Wang N, Cao J, Chen H, et al. Genetic characterization of H1N2 swine influenza virus isolated in China and its pathogenesis and inflammatory responses in mice.. Arch Virol. 2013. Abstract
submitted by kickingbird at Apr, 21, 2013 from Arch Virol. 2013 (via http://www.ncbi.nlm.nih.gov/pubmed/23591972)
In 2009, two H1N2 influenza viruses were isolated from trachea swabs of pigs in Hubei in China. We compared these sequences with the other 18 complete genome sequences of swine H1N2 isolates from China ... HUI DS, Lee N, Chan PK. Adjunctive therapies and immunomodulatory agents in the management of severe influenza. Antiviral Res. 2013 Apr 8. pii: S0166-3542(13)0008. Abstract
submitted by kickingbird at Apr, 21, 2013 from Antiviral Res. 2013 Apr 8. pii: S0166-3542(13)0008 (via http://www.ncbi.nlm.nih.gov/pubmed/23578727)
In addition to neuraminidase inhibitors and other drugs that directly target viral replication, a number of adjunctive and immunomodulatory therapies are currently under evaluation for the treatment of ... LAURSEN NS, Wilson IA. Broadly neutralizing antibodies against influenza viruses. Antiviral Res. 2013 Apr 9. pii: S0166-3542(13)0008. Abstract
submitted by kickingbird at Apr, 21, 2013 from Antiviral Res. 2013 Apr 9. pii: S0166-3542(13)0008 (via http://www.ncbi.nlm.nih.gov/pubmed/23583287)
Despite available antivirals and vaccines, influenza continues to be a major cause of mortality worldwide. Vaccination generally induces an effective, but strain-specific antibody response. As the virus ... Jonges M, Meijer A, Fouchier RA, Koch G, Li J, Pan. Guiding outbreak management by the use of influenza A(H7Nx) virus sequence analysis. Euro Surveill. 2013;18(16):pii=20460.. Full Text
submitted by kickingbird at Apr, 20, 2013 from Euro Surveill. 2013;18(16):pii=20460. (via http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=2)
The recently identified human infections with avian influenza A(H7N9) viruses in China raise important questions regarding possible source and risk to humans. Sequence comparison with an influenza A(H7N7) ... TAFESSE FG, Sanyal S, Ashour J, Guimaraes CP, et a. Intact sphingomyelin biosynthetic pathway is essential for intracellular transport of influenza virus glycoproteins.. Proc Natl Acad Sci U S A. 2013 Apr 1. Abstract
submitted by kickingbird at Apr, 14, 2013 from Proc Natl Acad Sci U S A. 2013 Apr 1 (via http://www.ncbi.nlm.nih.gov/pubmed/23576732)
Cells genetically deficient in sphingomyelin synthase-1 (SGMS1) or blocked in their synthesis pharmacologically through exposure to a serine palmitoyltransferase inhibitor (myriocin) show strongly reduced ... Baz M, Paskel M, Matsuoka Y, Zengel J, Cheng X, Ji. Replication and immunogenicity of swine, equine and avian H3 subtype influenza viruses in mice and ferrets. J Virol. 2013 Apr 10.. Abstract
submitted by kickingbird at Apr, 14, 2013 from J Virol. 2013 Apr 10. (via http://www.ncbi.nlm.nih.gov/pubmed/23576512)
Since it is difficult to predict which influenza virus subtype will cause an influenza pandemic, it is important to prepare influenza virus vaccines against different subtypes and evaluate the safety and ... RB Gao, B Cao,YW Hu, ZJ Feng, DY Wang, etc.,al. Human Infection with a Novel Avian-Origin Influenza A (H7N9) Virus. April 11, 2013DOI: 10.1056/NEJMoa1304459. Abstract
submitted by kickingbird at Apr, 12, 2013 from April 11, 2013DOI: 10.1056/NEJMoa1304459 (via http://www.nejm.org/doi/full/10.1056/NEJMoa1304459?query=fea)
Background
Infection of poultry with influenza A subtype H7 viruses occurs worldwide, but the introduction of this subtype to humans in Asia has not been observed previously. In March 2013, three urban ... Nicoll A, Danielsson N.. A novel reassortant avian influenza A(H7N9) virus in China – what are the implications for Europe. Euro Surveill. 2013;18(15):pii=20452.. Abstract
submitted by kickingbird at Apr, 12, 2013 from Euro Surveill. 2013;18(15):pii=20452. (via http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=2)
As of 10 April 2013, 33 human cases infected with a novel influenza A(H7N9) virus have been laboratory confirmed in Shanghai, Anhui, Jiangsu and Zhejiang provinces in China (Figure1). This case count came ... Feifei Yang, etc.,al. A fatal case caused by novel H7N9 avian influenza A virus in China. Emerging Microbes & Infections (2013) 2, e19. Full Text
submitted by kickingbird at Apr, 11, 2013 from Emerging Microbes & Infections (2013) 2, e19 (via http://www.nature.com/emi/journal/v2/n4/full/emi201322a.html)
Since the highly pathogenic H5N1 avian influenza virus (AIV) was first transmitted from birds to humans in Hong Kong in 1997, other pathogenic AIVs, including H7N2, H7N3, H7N7, and H9N2 have been reported ... CHAKRABARTI AK, Pasricha G.. An insight into the PB1F2 protein and its multifunctional role in enhancing the pathogenicity of the influenza A viruses. Virology. 2013 Mar 29. pii: S0042-6822(13)00130. Abstract
submitted by kickingbird at Apr, 7, 2013 from Virology. 2013 Mar 29. pii: S0042-6822(13)00130 (via http://www.ncbi.nlm.nih.gov/pubmed/23545143)
PB1F2 is the 11th protein of the influenza A virus. The protein has variable sizes with truncations either at the C- or N-terminal ends. The most recent example being the 2009 pandemic H1N1 virus which ... Wang S, Zhao Z, Bi Y, Sun L, et al.. Tyrosine 132 phosphorylation of influenza A virus M1 protein is crucial for virus replication by controlling its nuclear import. J Virol 2013. Abstract
submitted by kickingbird at Apr, 1, 2013 from J Virol 2013 (via http://www.ncbi.nlm.nih.gov/m/pubmed/23536660/)
Phosphorylation of viral protein plays important roles in the influenza A virus (IAV) life cycle. By using mass spectrometry, we have identified tyrosine (Y) 132 as a phosphorylation site of matrix protein ... Martinez-Romero C, de Vries E, Belicha-Villanueva. Substitutions T200A and E227A in the hemagglutinin of pandemic 2009 influenza A virus increase lethality but decrease transmission. J Virol 2013. Abstract
submitted by kickingbird at Apr, 1, 2013 from J Virol 2013 (via http://www.ncbi.nlm.nih.gov/m/pubmed/23536663/)
We describe that swine influenza virus-like substitutions T200A and E227A in the hemagglutinin of the 2009 pandemic influenza virus alter its pathogenesis and transmission. Viral replication is increased ... 8128 items, 20/Page, Page[302/407][|<<] [|<] [301] [302] [303] [304] [305] [306] [307] [308] [309] [310] [>|] [>>|] |
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