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2024-7-18 3:34:19
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Guo L, Zhang X, Ren L, Yu X, Chen L, Zhou H, et al. Human Antibody Responses to Avian Influenza A(H7N9) Virus, 2013. 2013. Emerg Infect Dis. 2014 Feb.  Abstract  
submitted by kickingbird at Jan, 27, 2014 from 2013. Emerg Infect Dis. 2014 Feb (via http://wwwnc.cdc.gov/eid/article/20/2/13-1094_article.htm)
Understanding host antibody response is crucial for predicting disease severity and for vaccine development. We investigated antibody responses against influenza A(H7N9) virus in 48 serum samples from ...

Komadina N, McVernon J, Hall R, Leder K.. A Historical Perspective of Influenza A(H1N2) Virus. Emerg Infect Dis. 2014 Jan.  Abstract  
submitted by kickingbird at Jan, 27, 2014 from Emerg Infect Dis. 2014 Jan (via http://wwwnc.cdc.gov/eid/article/20/1/12-1848_article.htm)
The emergence and transition to pandemic status of the influenza A(H1N1)A(H1N1)pdm09) virus in 2009 illustrated the potential for previously circulating human viruses to re-emerge in humans and cause a ...

Westgeest KB, Russell CA, Lin X, Spronken MI, et a. Genome-wide Analysis of Reassortment and Evolution of Human Influenza A(H3N2) Viruses Circulating between 1968 and 2011. J Virol 2013..  Abstract  
submitted by kickingbird at Jan, 4, 2014 from J Virol 2013. (via http://www.ncbi.nlm.nih.gov/m/pubmed/24371052/)
Influenza A(H3N2) viruses became widespread in humans during the 1968 H3N2 virus pandemic and have been a major cause of influenza epidemics ever since. The viruses evolve continuously by reassortment ...

Yamayoshi S, Yamada S, Fukuyama S, Murakami S, et. Virulence-Affecting Amino Acid Changes in the PA Protein of H7N9 Influenza A Viruses. J Virol 2013.  Abstract  
submitted by kickingbird at Jan, 4, 2014 from J Virol 2013 (via http://www.ncbi.nlm.nih.gov/m/pubmed/24371069/)
Novel avian-origin influenza A(H7N9) viruses were first reported to infect humans in March 2013. To date, 143 human cases, including 45 deaths, have been recorded. By using sequence comparisons and phylogenetic ...

Bissel SJ, Wang G, Carter DM, Crevar CJ, et al.. H1N1, but not H3N2, influenza A virus infection protects ferrets from H5N1 encephalitis. J Virol 2013..  Abstract  
submitted by kickingbird at Jan, 4, 2014 from J Virol 2013. (via http://www.ncbi.nlm.nih.gov/m/pubmed/24371072/)
Seasonal influenza causes substantial morbidity and mortality because of efficient human-to-human spread. Rarely, zoonotic strains of influenza virus spread to humans, where they have the potential to ...

Binh NT, Wakai C, Kawaguchi A, Nagata K, et al. Involvement of the N-terminal portion of influenza virus RNA polymerase subunit PB1 in nucleotide recognition. Biochem Biophys Res Commun 2013 Dec 19. pii: S0006.  Abstract  
submitted by kickingbird at Jan, 4, 2014 from Biochem Biophys Res Commun 2013 Dec 19. pii: S0006 (via http://www.ncbi.nlm.nih.gov/m/pubmed/24361882/)
The influenza virus PB1 protein functions as a catalytic subunit of the viral RNA-dependent RNA polymerase and contains the highly conserved motifs of RNA-dependent RNA polymerases together with putative ...

Varich NL, Sadykova GK, Prilipov AG, Kochergin-Nik. Location and architecture of an antibody-binding site of influenza A virus nucleoprotein. Arch Virol 2013.  Abstract  
submitted by kickingbird at Jan, 4, 2014 from Arch Virol 2013 (via http://www.ncbi.nlm.nih.gov/m/pubmed/24357080/)
Amino acid positions recognized by monoclonal antibodies (MAbs) in the influenza A virus nucleoprotein (NP) have been reported. As these residues were scattered in the three-dimensional (3D) structure ...

KIM JC, Kim HM, Kang YM, Ku KB, et al.. Severe pathogenesis of influenza B virus in pregnant mice. Virology. 2014;448:74-81..  Abstract  
submitted by kickingbird at Dec, 16, 2013 from Virology. 2014;448:74-81. (via http://www.ncbi.nlm.nih.gov/m/pubmed/24314638/)
The study on pathogenesis of influenza B virus during pregnancy is limited. Here, we showed using a mouse model that influenza B virus could cause severe disease including death during pregnancy. Infected ...

KRAMMER F, Margine I, Hai R, Flood A, et al. H3 stalk-based chimeric hemagglutinin influenza virus constructs protect mice from H7N9 challenge. J Virol. 2013 Dec 4.  Abstract  
submitted by kickingbird at Dec, 16, 2013 from J Virol. 2013 Dec 4 (via http://www.ncbi.nlm.nih.gov/m/pubmed/24307585/)
The recent outbreak of H7N9 influenza virus infections in humans in China has raised concerns about the pandemic potential of this strain. Here we test the efficacy of H3-stalk based chimeric hemagglutinin ...

JOB ER, Bottazzi B, Short KR, Deng YM, et al.. A Single Amino Acid Substitution in the Hemagglutinin of H3N2 Subtype Influenza A Viruses Is Associated with Resistance to the Long Pentraxin PTX3 and Enhanced Virulence in Mice. J Immunol. 2013.  Abstract  
submitted by kickingbird at Dec, 16, 2013 from J Immunol. 2013 (via http://www.ncbi.nlm.nih.gov/m/pubmed/24307735/)
The long pentraxin, pentraxin 3 (PTX3), can play beneficial or detrimental roles during infection and disease by modulating various aspects of the immune system. There is growing evidence to suggest that ...

JARU-AMPORNPAN P, Narkpuk J, Wanitchang A, Jongkae. Nucleoprotein of influenza B virus binds to its type A counterpart and disrupts influenza A viral polymerase complex formation. Biochem Biophys Res Commun. 2013 Dec 2. pii: S0006.  Abstract  
submitted by kickingbird at Dec, 16, 2013 from Biochem Biophys Res Commun. 2013 Dec 2. pii: S0006 (via http://www.ncbi.nlm.nih.gov/m/pubmed/24309113/)
Upon co-infection with influenza B virus (FluB), influenza A virus (FluA) replication is substantially impaired. Previously, we have shown that the nucleoprotein of FluB (BNP) can inhibit FluA polymerase ...

TARBET EB, Vollmer AH, Hurst BL, Barnard DL, et al. In vitro activity of favipiravir and neuraminidase inhibitor combinations against oseltamivir-sensitive and oseltamivir-resistant pandemic influenza A (H1N1) virus. Arch Virol. 2013.  Abstract  
submitted by kickingbird at Dec, 16, 2013 from Arch Virol. 2013 (via http://www.ncbi.nlm.nih.gov/m/pubmed/24311151/)
Few anti-influenza drugs are licensed in the United States for the prevention and therapy of influenza A and B virus infections. This shortage, coupled with continuously emerging drug resistance, as detected ...

Zhang A, Huang Y, Tian D, Lau EH, Wan Y, Liu X,. Kinetics of serological responses in influenza A(H7N9)-infected patients correlate with clinical outcome in China, 2013. Euro Surveill. 2013;18(50):pii=20657.  Abstract  
submitted by kickingbird at Dec, 13, 2013 from Euro Surveill. 2013;18(50):pii=20657 (via http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=2)
Introduction A novel avian influenza A(H7N9) infection emerged to cause an outbreak in the Yangtze River delta in early 2013, subsequently spreading to other provinces in China [1-4]. In the first wave ...

Hai, R. et al. Influenza A(H7N9) virus gains neuraminidase inhibitor resistance without loss of in vivo virulence or transmissibility. Nature Communications 4, Article number: 2854.  Abstract  
submitted by kickingbird at Dec, 13, 2013 from Nature Communications 4, Article number: 2854 (via http://www.nature.com/ncomms/2013/131210/ncomms3854/full/nco)
Without baseline human immunity to the emergent avian influenza A(H7N9) virus, neuraminidase inhibitors are vital for controlling viral replication in severe infections. An amino acid change in the viral ...

Rui Xu,m etc.,al. Preferential Recognition of Avian-Like Receptors in Human Influenza A H7N9 Viruses. Science 6 December 2013.  Abstract  
submitted by kickingbird at Dec, 10, 2013 from Science 6 December 2013 (via http://www.sciencemag.org/content/342/6163/1230.abstract?sid)
The 2013 outbreak of avian-origin H7N9 influenza in eastern China has raised concerns about its ability to transmit in the human population. The hemagglutinin glycoprotein of most human H7N9 viruses carries ...

Liu W, Yang K, Qi X, Xu K, Ji H, Ai J, Ge A, Wu Y,. Spatial and temporal analysis of human infection with avian influenza A(H7N9) virus in China, 2013. Euro Surveill. 2013;18(47):pii=20640..  Abstract  
submitted by kickingbird at Nov, 22, 2013 from Euro Surveill. 2013;18(47):pii=20640. (via http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=2)
Descriptive and geographic information system methods were used to depict the spatial and temporal characteristics of the outbreak of human infection with a novel avian influenza A(H7N9) virus in mainland ...

N Cao, Etc.,al. Avian influenza A (H5N1) virus antibodies in pigs and residents of swine farms, southern China. JCV.  Abstract  
submitted by kickingbird at Nov, 18, 2013 from JCV (via http://www.journalofclinicalvirology.com/article/S1386-6532()
Abstract  Background Since 1997, the H5 avian influenza viruses (AIVs) circulating in China have become an international concern. Clade 2.3.2 of H5N1 AIVs is genetically distinct from the viruses ...

WONG KK, Jain S, Blanton L, Dhara R, et al. Influenza-Associated Pediatric Deaths in the United States, 2004-2012. Pediatrics. 2013 Oct 28.  Abstract  
submitted by kickingbird at Nov, 4, 2013 from Pediatrics. 2013 Oct 28 (via http://www.ncbi.nlm.nih.gov/pubmed/24167165)
BACKGROUND:Influenza-associated deaths in children occur annually. We describe the epidemiology of influenza-associated pediatric deaths from the 2004-2005 through the 2011-2012 influenza seasons.METHODS:Deaths ...

MEDINA J, Guillot V, Totain E, Rouleau M, et al. Vero/CHOK1, a novel mixture of cell lines that is optimal for the rescue of influenza A vaccine seeds. J Virol Methods. 2013 Oct 23.  Abstract  
submitted by kickingbird at Nov, 4, 2013 from J Virol Methods. 2013 Oct 23 (via http://www.ncbi.nlm.nih.gov/pubmed/24161812)
Seasonal and pandemic influenza vaccine manufacturing is challenged with a tight production schedule. Reverse genetics constitutes a rapid method for creating viruses. Vero and CHOK1 cells were found to ...

ALYMOVA IV, Samarasinghe A, Vogel P, Green AM, et. A novel cytotoxic sequence contributes to influenza A protein PB1-F2 pathogenicity and predisposition to secondary bacterial infection. J Virol. 2013 Oct 30.  Abstract  
submitted by kickingbird at Nov, 4, 2013 from J Virol. 2013 Oct 30 (via http://www.ncbi.nlm.nih.gov/pubmed/24173220)
Enhancement of cell death is a distinguishing feature of H1N1 influenza virus A/Puerto Rico/8/34 protein PB1-F2. Comparing the sequences (amino acids [a.a.] 61-87 using PB1-F2 a.a. numbering) of the PB1-F2-derived ...

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