Ravanetti L, et al. IL-33 drives influenza-induced asthma exacerbations by halting innate and adaptive anti-viral immunity. J Allergy Clin Immunol. 2018 Oct 11. Abstract
submitted by kickingbird at Oct, 17, 2018 from J Allergy Clin Immunol. 2018 Oct 11 (via https://www.ncbi.nlm.nih.gov/pubmed/30316823)
BACKGROUND: Influenza virus triggers severe exacerbations of asthma for which no adequate treatment is available. It is known that IL-33 levels correlate with exacerbation severity, but its role in the ... Noshi T, et al. In vitro characterization of baloxavir acid, a first-in-class cap-dependent endonuclease inhibitor of the influenza virus polymerase PA subunit. Antiviral Res. 2018 Oct 11. Abstract
submitted by kickingbird at Oct, 17, 2018 from Antiviral Res. 2018 Oct 11 (via https://www.ncbi.nlm.nih.gov/pubmed/30316915)
Cap-dependent endonuclease (CEN) resides in the PA subunit of the influenza virus and mediates the critical "cap-snatching" step of viral RNA transcription, which is considered to be a promising anti-influenza ... Fox J, Barbour S, Junco SJ. Central nervous system laboratory-confirmed influenza meningo-encephalitis treated with peramivir. Int J Antimicrob Agents. 2018 Oct;52(4):517-518.. Abstract
submitted by kickingbird at Oct, 17, 2018 from Int J Antimicrob Agents. 2018 Oct;52(4):517-518. (via https://www.ncbi.nlm.nih.gov/pubmed/30318059)
Influenza-associated meningo-encephalitis (IAE) is a rare complication of influenza. The optimal therapy is not known, and oseltamivir has limited central nervous system (CNS) penetration. We report a ... Sasaki E, et al. Establishment of a novel safety assessment method for vaccine adjuvant development. Vaccine. 2018 Oct 11. Abstract
submitted by kickingbird at Oct, 17, 2018 from Vaccine. 2018 Oct 11 (via https://www.ncbi.nlm.nih.gov/pubmed/30318166)
Vaccines effectively prevent infectious diseases. Many types of vaccines against various pathogens that threaten humans are currently in widespread use. Recently, adjuvant adaptation has been attempted ... Zou G, et al. Comprehensive analysis of N-glycans in IgG purified from ferrets with or without influenza A virus infection. J Biol Chem. 2018 Oct 12.. Abstract
submitted by kickingbird at Oct, 17, 2018 from J Biol Chem. 2018 Oct 12. (via https://www.ncbi.nlm.nih.gov/pubmed/30315103)
Influenza viruses cause contagious respiratory infections resulting in significant economic burdens to communities. Production of influenza-specific immunoglobulins, specifically IgGs, is one of the major ... Jonas M, et al. Identification of avian influenza virus subtype H9N2 in chicken farms in Indonesia. Prev Vet Med. 2018 Nov 1;159:99-105.. Abstract
submitted by kickingbird at Oct, 17, 2018 from Prev Vet Med. 2018 Nov 1;159:99-105. (via https://www.ncbi.nlm.nih.gov/pubmed/30314797)
Avian influenza virus subtype H9N2 (AIV-H9N2) has become established in domestic poultry in Asia and Africa. AIV-H9N2 has not been reported previously in Indonesia. Here we describe the presence of AIV-H9N2 ... Thompson MG, et al. Influenza Vaccine Effectiveness in Preventing Influenza-associated Hospitalizations During Pregnancy: A Multi-country Retrospective Test Negative Design Study, 2010-2016. Clin Infect Dis. 2018 Oct 11.. Abstract
submitted by kickingbird at Oct, 15, 2018 from Clin Infect Dis. 2018 Oct 11. (via https://www.ncbi.nlm.nih.gov/pubmed/30307490)
Background: To date, no study has examined influenza vaccine effectiveness (IVE) against laboratory-confirmed influenza-associated hospitalizations during pregnancy.Methods: The Pregnancy Influenza Vaccine ... Jegede A, Fu Q, Lin M, Kumar A, Guan J. Aerosol exposure enhanced infection of low pathogenic avian influenza viruses in chickens. Transbound Emerg Dis. 2018 Oct 11.. Abstract
submitted by kickingbird at Oct, 15, 2018 from Transbound Emerg Dis. 2018 Oct 11. (via https://www.ncbi.nlm.nih.gov/pubmed/30307712)
To assess the impact of different routes of inoculation on experimental infection of avian influenza (AI) viruses in chickens, this study compared virus replication and cytokine gene expression in respiratory ... Zimmer C, Leuba SI, Yaesoubi R, Cohen T. Use of daily Internet search query data improves real-time projections of influenza epidemics. J R Soc Interface. 2018 Oct 10;15(147).. Abstract
submitted by kickingbird at Oct, 15, 2018 from J R Soc Interface. 2018 Oct 10;15(147). (via https://www.ncbi.nlm.nih.gov/pubmed/30305417)
Seasonal influenza causes millions of illnesses and tens of thousands of deaths per year in the USA alone. While the morbidity and mortality associated with influenza is substantial each year, the timing ... Sun X, et al. Risk assessment of fifth-wave H7N9 influenza A viruses in mammalian models. J Virol. 2018 Oct 10.. Abstract
submitted by kickingbird at Oct, 15, 2018 from J Virol. 2018 Oct 10. (via https://www.ncbi.nlm.nih.gov/pubmed/30305359)
The fifth-wave of the H7N9 influenza epidemic in China was distinguished by a sudden increase in human infections, an extended geographic distribution, and the emergence of highly pathogenic avian influenza ... Tome-Amat J, et al. Influenza A virus utilizes low affinity, high avidity interactions with the nuclear import machinery to ensure infection and immune evasion. J Virol. 2018 Oct 10. Abstract
submitted by kickingbird at Oct, 15, 2018 from J Virol. 2018 Oct 10 (via https://www.ncbi.nlm.nih.gov/pubmed/30305352)
The incoming influenza A virus (IAV) genome must pass through two distinct barriers in order to establish infection in the cell- the plasma membrane and the nuclear membrane. A precise understanding of ... Shi B, et al. Identifying key bird species and geographical hotspots of avian influenza A (H7N9) virus in China. Infect Dis Poverty. 2018 Oct 11;7(1):97.. Abstract
submitted by kickingbird at Oct, 15, 2018 from Infect Dis Poverty. 2018 Oct 11;7(1):97. (via https://www.ncbi.nlm.nih.gov/pubmed/30305184)
BACKGROUND: In China since the first human infection of avian influenza A (H7N9) virus was identified in 2013, it has caused serious public health concerns due to its wide spread and high mortality rate. ... Wang L, et al. Inhibition of autophagy and chemokine induction by sphingosine 1-phosphate receptor 1 through NF-κB signaling in human pulmonary endothelial cells infected with influenza A viruses. PLoS One. 2018 Oct 10;13(10):e0205344.. Abstract
submitted by kickingbird at Oct, 15, 2018 from PLoS One. 2018 Oct 10;13(10):e0205344. (via https://www.ncbi.nlm.nih.gov/pubmed/30304001)
Endothelial cells have been considered the central regulators of cytokine storm in the respiratory system during influenza virus infection. Studies have found that elevated autophagy could be an essential ... Nooruzzaman M, Haque ME, Chowdhury EH, Islam MR. Pathology of Clade 2.3.2.1 Avian Influenza Virus (H5N1) Infection in Quails and Ducks in Bangladesh. Avian Pathol. 2018 Oct 10:1-21. Abstract
submitted by kickingbird at Oct, 15, 2018 from Avian Pathol. 2018 Oct 10:1-21 (via https://www.ncbi.nlm.nih.gov/pubmed/30303027)
We performed pathological and molecular virological investigation of three outbreaks of highly pathogenic avian influenza (HPAI) in a quail farm and two duck farms of Mymensingh and Netrokona districts ... Wu H, et al. Molecular characterization of H10 subtype avian influenza viruses isolated from poultry in Eastern China. Arch Virol. 2018 Oct 9. Abstract
submitted by kickingbird at Oct, 15, 2018 from Arch Virol. 2018 Oct 9 (via https://www.ncbi.nlm.nih.gov/pubmed/30302582)
In recent years, avian-origin H10 influenza viruses have proved capable of infecting human beings, and they pose a potential public health threat. Seven H10 avian influenza viruses (AIVs), H10N3 (n?=?2), ... Akand EH, Downard KM. Ancestral and Compensatory Mutations that Promote Antiviral Resistance in Influenza N1 Neuraminidase Revealed by a Phylonumerics Approach. J Mol Evol. 2018 Oct 9.. Abstract
submitted by kickingbird at Oct, 15, 2018 from J Mol Evol. 2018 Oct 9. (via https://www.ncbi.nlm.nih.gov/pubmed/30302501)
Implementation of a new phylonumerics approach to construct a mass tree representing over 6000 H1N1 human influenza strains has enabled ancestral and compensatory descendant mutations to be identified ... Vom Steeg LG, Klein SL. Sex and sex steroids impact influenza pathogenesis across the life course. Semin Immunopathol. 2018 Oct 8. Abstract
submitted by kickingbird at Oct, 15, 2018 from Semin Immunopathol. 2018 Oct 8 (via https://www.ncbi.nlm.nih.gov/pubmed/30298431)
Males and females differ in the outcome of influenza A virus (IAV) infections, which depends significantly on age. During a typical seasonal influenza epidemic, young children ( Loebermann M, et al. A phase III, open-label, single-arm, study to evaluate the safety and immunogenicity of a trivalent, surface antigen inactivated subunit influenza virus vaccine produced in mammalian cell culture (Opt. Infection. 2018 Oct 8.. Abstract
submitted by kickingbird at Oct, 15, 2018 from Infection. 2018 Oct 8. (via https://www.ncbi.nlm.nih.gov/pubmed/30298473)
Vaccination is an essential tool in reducing the impact of seasonal influenza infections. The viral strains responsible for seasonal outbreaks vary annually, and preventive vaccines have to be adapted ... Lee N, Hurt AC. Neuraminidase inhibitor resistance in influenza: a clinical perspective. Curr Opin Infect Dis. 2018 Oct 6.. Abstract
submitted by kickingbird at Oct, 15, 2018 from Curr Opin Infect Dis. 2018 Oct 6. (via https://www.ncbi.nlm.nih.gov/pubmed/30299356)
PURPOSE OF REVIEW: Neuraminidase inhibitors (NAIs), including oseltamivir, zanamivir, and peramivir, is the main class of antiviral available for clinical use. As such, development of resistance toward ... Beigel JH. Polyclonal and monoclonal antibodies for the treatment of influenza. Curr Opin Infect Dis. 2018 Oct 5.. Abstract
submitted by kickingbird at Oct, 15, 2018 from Curr Opin Infect Dis. 2018 Oct 5. (via https://www.ncbi.nlm.nih.gov/pubmed/30299360)
PURPOSE OF REVIEW: This review summarizes past and ongoing efforts for using polyclonal and monoclonal antibodies for the treatment of influenza, and is focused on products that have entered clinical trials.RECENT ... 8128 items, 20/Page, Page[219/407][|<<] [|<] [211] [212] [213] [214] [215] [216] [217] [218] [219] [220] [>|] [>>|] |
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