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2024-11-25 6:43:18
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Ndumu D, et al. Highly pathogenic avian influenza H5N8 Clade 2.3.4.4B virus in Uganda, 2017. Infect Genet Evol. 2018 Oct 17..  Abstract  
submitted by kickingbird at Oct, 21, 2018 from Infect Genet Evol. 2018 Oct 17. (via https://www.ncbi.nlm.nih.gov/pubmed/30342095)
In early January 2017, outbreaks of H5N8 highly pathogenic avian influenza (HPAI) were reported for the first time in wild and domestic birds along the shores and on some islands of Lake Victoria, in central-southern ...

Martínez-Sobrido L, Peersen O, Nogales A.. Temperature Sensitive Mutations in Influenza A Viral Ribonucleoprotein Complex Responsible for the Attenuation of the Live Attenuated Influenza Vaccine. Viruses. 2018 Oct 15;10(10).  Abstract  
submitted by kickingbird at Oct, 18, 2018 from Viruses. 2018 Oct 15;10(10) (via https://www.ncbi.nlm.nih.gov/pubmed/30326610)
Live attenuated influenza vaccines (LAIV) have prevented morbidity and mortality associated with influenza viral infections for many years and represent the best therapeutic option to protect against influenza ...

Mahesutihan M, et al. CypA Regulates AIP4-Mediated M1 Ubiquitination of Influenza A Virus. Virol Sin. 2018 Oct 16.  Abstract  
submitted by kickingbird at Oct, 18, 2018 from Virol Sin. 2018 Oct 16 (via https://www.ncbi.nlm.nih.gov/pubmed/30328013)
Cyclophilin A (CypA) is a peptidyl-prolyl cis/trans isomerase that interacts with the matrix protein (M1) of influenza A virus (IAV) and restricts virus replication by regulating the ubiquitin-proteasome-mediated ...

Shirey KA, et al. Novel role of gastric releasing peptide-mediated signaling in the host response to influenza infection. Mucosal Immunol. 2018 Oct 16..  Abstract  
submitted by kickingbird at Oct, 18, 2018 from Mucosal Immunol. 2018 Oct 16. (via https://www.ncbi.nlm.nih.gov/pubmed/30327535)
Gastrin-releasing peptide (GRP) is an evolutionarily well-conserved neuropeptide that was originally recognized for its ability to mediate gastric acid secretion in the gut. More recently, however, GRP ...

He J, et al. Genetic characterization of the first detected human case of avian influenza A (H5N6) in Anhui Province, East China. Sci Rep. 2018 Oct 16;8(1):15282.  Abstract  
submitted by kickingbird at Oct, 18, 2018 from Sci Rep. 2018 Oct 16;8(1):15282 (via https://www.ncbi.nlm.nih.gov/pubmed/30327485)
We compared complete genome sequences of two strains of an avian influenza A (H5N6) virus isolated from a patient in Anhui Province with those of other strains from GenBank and Global initiative on sharing ...

Tokars JI, Rolfes MA, Foppa IM, Reed C. An evaluation and update of methods for estimating the number of influenza cases averted by vaccination in the United States. Vaccine. 2018 Oct 13.  Abstract  
submitted by kickingbird at Oct, 18, 2018 from Vaccine. 2018 Oct 13 (via https://www.ncbi.nlm.nih.gov/pubmed/30327213)
INTRODUCTION: To evaluate the public health benefit of yearly influenza vaccinations, CDC estimates the number of influenza cases and hospitalizations averted by vaccine. Available input data on cases ...

Kissler SM, et al. Geographic transmission hubs of the 2009 influenza pandemic in the United States. Epidemics. 2018 Oct 10..  Abstract  
submitted by kickingbird at Oct, 18, 2018 from Epidemics. 2018 Oct 10. (via https://www.ncbi.nlm.nih.gov/pubmed/30327253)
A key issue in infectious disease epidemiology is to identify and predict geographic sites of epidemic establishment that contribute to onward spread, especially in the context of invasion waves of emerging ...

Geneviève LD, et al. Research Ethics in the European Influenzanet Consortium: Scoping Review. JMIR Public Health Surveill. 2018 Oct 10;4(4):e67..  Abstract  
submitted by kickingbird at Oct, 18, 2018 from JMIR Public Health Surveill. 2018 Oct 10;4(4):e67. (via https://www.ncbi.nlm.nih.gov/pubmed/30305258)
BACKGROUND: Influenzanet was launched in several European countries to monitor influenza-like illness during flu seasons with the help of volunteering participants and Web-based technologies. As in the ...

Er JZ, Koean RAG, Ding JL. Loss of T-bet confers survival advantage to influenza-bacterial superinfection. EMBO J. 2018 Oct 15..  Abstract  
submitted by kickingbird at Oct, 18, 2018 from EMBO J. 2018 Oct 15. (via https://www.ncbi.nlm.nih.gov/pubmed/30322895)
The transcription factor, T-bet, regulates type 1 inflammatory responses against a range of infections. Here, we demonstrate a previously unaddressed role of T-bet, to influenza virus and bacterial superinfection. ...

Krischuns T, et al. Phosphorylation of TRIM28 Enhances the Expression of IFN-β and Proinflammatory Cytokines During HPAIV Infection of Human Lung Epithelial Cells. Front Immunol. 2018 Sep 28;9:2229..  Abstract  
submitted by kickingbird at Oct, 18, 2018 from Front Immunol. 2018 Sep 28;9:2229. (via https://www.ncbi.nlm.nih.gov/pubmed/30323812)
Human infection with highly pathogenic avian influenza viruses (HPAIV) is often associated with severe tissue damage due to hyperinduction of interferons and proinflammatory cytokines. The reasons for ...

Barr IG, et al. Cell culture-derived influenza vaccines in the severe 2017-2018 epidemic season: a step towards improved influenza vaccine effectiveness. NPJ Vaccines. 2018 Oct 9;3:44.  Abstract  
submitted by kickingbird at Oct, 18, 2018 from NPJ Vaccines. 2018 Oct 9;3:44 (via https://www.ncbi.nlm.nih.gov/pubmed/30323955)
The 2017-2018 seasonal influenza epidemics were severe in the US and Australia where the A(H3N2) subtype viruses predominated. Although circulating A(H3N2) viruses did not differ antigenically from that ...

Claeys C, et al. Anamnestic Immune Response and Safety of an Inactivated Quadrivalent Influenza Vaccine in Primed Versus Vaccine-Na?ve Children. Pediatr Infect Dis J. 2018 Oct 15..  Abstract  
submitted by kickingbird at Oct, 18, 2018 from Pediatr Infect Dis J. 2018 Oct 15. (via https://www.ncbi.nlm.nih.gov/pubmed/30325891)
BACKGROUND: It has not yet been demonstrated whether two doses of inactivated quadrivalent influenza vaccine (IIV4) prime a booster response in infants. We evaluated the anamnestic immune response to an ...

Cui X, et al. A 113-amino-acid truncation at the NS1 C-terminus is a determinant for viral replication of H5N6 avian influenza virus in vitro and in vivo. Vet Microbiol. 2018 Nov;225:6-16.  Abstract  
submitted by kickingbird at Oct, 18, 2018 from Vet Microbiol. 2018 Nov;225:6-16 (via https://www.ncbi.nlm.nih.gov/pubmed/30322535)
Virulence of highly pathogenic avian influenza viruses (AIV) is determined by multiple genes and their encoded proteins. In particular, the nonstructural protein 1 (NS1) of viruses is a multifunctional ...

Wu NC, et al. Recurring and Adaptable Binding Motifs in Broadly Neutralizing Antibodies to Influenza Virus Are Encoded on the D3-9 Segment of the Ig Gene. Cell Host Microbe. 2018 Oct 10;24(4):569-578.e4.  Abstract  
submitted by kickingbird at Oct, 18, 2018 from Cell Host Microbe. 2018 Oct 10;24(4):569-578.e4 (via https://www.ncbi.nlm.nih.gov/pubmed/30308159)
Discovery and characterization of broadly neutralizing antibodies (bnAbs) to the influenza hemagglutinin (HA) stem have provided insights for the development of a universal flu vaccine. Identification ...

Vera Ehrenstein, et al. Oseltamivir in pregnancy and birth outcomes. BMC Infectious Diseases201818:519.  Abstract  
submitted by kickingbird at Oct, 18, 2018 from BMC Infectious Diseases201818:519 (via https://bmcinfectdis.biomedcentral.com/articles/10.1186/s128)
BackgroundPrenatal exposure to influenza or fever is associated with risk of congenital malformations. Oseltamivir is used to treat influenza and to provide post-exposure prophylaxis. We examined the association ...

Tomar J, et al. Passive inhalation of dry powder influenza vaccine formulations completely protects chickens against H5N1 lethal viral challenge. Eur J Pharm Biopharm. 2018 Oct 9..  Abstract  
submitted by kickingbird at Oct, 17, 2018 from Eur J Pharm Biopharm. 2018 Oct 9. (via https://www.ncbi.nlm.nih.gov/pubmed/30312742)
Bird to human transmission of high pathogenicity avian influenza virus (HPAIV) poses a significant risk of triggering a flu pandemic in the human population. Therefore, vaccination of susceptible poultry ...

Tsujimura K, et al. Effect of Influenza Vaccine in Patients With Kidney Transplant. Transplant Proc. 2018 Oct;50(8):2443-2446..  Abstract  
submitted by kickingbird at Oct, 17, 2018 from Transplant Proc. 2018 Oct;50(8):2443-2446. (via https://www.ncbi.nlm.nih.gov/pubmed/30316375)
BACKGROUND: Among infectious diseases, influenza is the most common cause of infection in Japan and worldwide. We aimed to evaluate the effect of influenza vaccination in kidney transplantation (KTx) recipients.METHODS: ...

Retkute R, et al. Dynamics of the 2004 avian influenza H5N1 outbreak in Thailand: The role of duck farming, sequential model fitting and control. Prev Vet Med. 2018 Nov 1;159:171-181.  Abstract  
submitted by kickingbird at Oct, 17, 2018 from Prev Vet Med. 2018 Nov 1;159:171-181 (via https://www.ncbi.nlm.nih.gov/pubmed/30314780)
The Highly Pathogenic Avian Influenza (HPAI) subtype H5N1 virus persists in many countries and has been circulating in poultry, wild birds. In addition, the virus has emerged in other species and frequent ...

Zhang J, et al. Role of c-Jun terminal kinase (JNK) activation in influenza A virus-induced autophagy and replication. Virology. 2018 Oct 10;526:1-12..  Abstract  
submitted by kickingbird at Oct, 17, 2018 from Virology. 2018 Oct 10;526:1-12. (via https://www.ncbi.nlm.nih.gov/pubmed/30316042)
The non-structural protein 1 (NS1) of different influenza A virus (IAV) strains can differentially regulate the activity of c-Jun terminal kinase (JNK) and PI-3 kinase (PI3K). Whether varying JNK and PI3K ...

Macdonald-Laurs E, et al. CSF neopterin, a useful biomarker in children presenting with influenza associated encephalopathy?. Eur J Paediatr Neurol. 2018 Sep 28..  Abstract  
submitted by kickingbird at Oct, 17, 2018 from Eur J Paediatr Neurol. 2018 Sep 28. (via https://www.ncbi.nlm.nih.gov/pubmed/30316638)
PURPOSE: Neurological complications of influenza cause significant disease in children. Central nervous system inflammation, the presumed mechanism of influenza-associated encephalopathy, is difficult ...

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