El Guerche-Séblain C, et al. Epidemiology and timing of seasonal influenza epidemics in the Asia-Pacific region, 2010-2017: implications for influenza vaccination programs. BMC Public Health. 2019 Mar 21;19(1):331. Abstract submitted by kickingbird at Mar, 24, 2019 from BMC Public Health. 2019 Mar 21;19(1):331 (via https://bmcpublichealth.biomedcentral.com/articles/10.1186/s) BACKGROUND: Description of the epidemiology of influenza is needed to inform influenza vaccination policy. Here we examined influenza virus circulation in countries in the Asia-Pacific region and compared ... Kumar P, et al. IL-27 promotes NK cell effector functions via Maf-Nrf2 pathway during influenza infection. Sci Rep. 2019 Mar 21;9(1):4984. Abstract submitted by kickingbird at Mar, 24, 2019 from Sci Rep. 2019 Mar 21;9(1):4984 (via https://www.nature.com/articles/s41598-019-41478-6) Influenza virus targets epithelial cells in the upper respiratory tract. Natural Killer (NK) cell-mediated early innate defense responses to influenza infection include the killing of infected epithelial ... Niakan Kalhori SR, Ghazisaeedi M, Azizi R, et al. Studying the influence of mass media and environmental factors on influenza virus transmission in the US Midwest. Public Health. 2019 Mar 19;170:17-22. Abstract submitted by kickingbird at Mar, 24, 2019 from Public Health. 2019 Mar 19;170:17-22 (via https://www.sciencedirect.com/science/article/pii/S003335061) OBJECTIVES: Disease burden and high financial cost of seasonal influenza emphasize the importance of studying the epidemics transmission dynamics. Our aim in this article is to extend the Susceptible Exposed ... Zheng H, et al. Evolved avian influenza virus (H7N9) isolated from human cases in a middle Yangtze River city in China, from February to April 2017. Heliyon. 2019 Mar 7;5(3):e01253.. Abstract submitted by kickingbird at Mar, 24, 2019 from Heliyon. 2019 Mar 7;5(3):e01253. (via https://www.heliyon.com/article/e01253) Seven cases of avian influenza A H7N9 virus infection were reported from February to April 2017 in Changsha City. Viral genome was acquired by RT-PCR, aligned with other H7N9 viruses using Clustal W, and ... Gandhi-Banga S, et al. Enhanced passive safety surveillance of three marketed influenza vaccines in the UK and the Republic of Ireland during the 2017/18 season. Hum Vaccin Immunother. 2019 Mar 21.. Abstract submitted by kickingbird at Mar, 23, 2019 from Hum Vaccin Immunother. 2019 Mar 21. (via https://www.ncbi.nlm.nih.gov/pubmed/30897026) Safety surveillance is required for each season's influenza vaccines to rapidly detect and evaluate potential new safety concerns before the peak period of immunization. Here we report the results of an ... Wang Y, et al. Comparative Outcomes of Adults Hospitalized With Seasonal Influenza A or B Virus Infection: Application of the 7-Category Ordinal Scale. Open Forum Infect Dis. 2019 Feb 15;6(3):ofz053. Abstract submitted by kickingbird at Mar, 23, 2019 from Open Forum Infect Dis. 2019 Feb 15;6(3):ofz053 (via https://academic.oup.com/ofid/article/6/3/ofz053/5320627) Background: The objective of this study was to investigate the difference in disease severity between influenza A and B among hospitalized adults using a novel ordinal scale and existing clinical outcome ... Peng C, Hou G, Li J, Cheng S, Wang S, Yi Y,. Isolation and characterization of a novel H7N8 avian influenza virus from domestic ducks in Central China in 2017. Virus Genes. 2019 Mar 20. Abstract submitted by kickingbird at Mar, 23, 2019 from Virus Genes. 2019 Mar 20 (via https://link.springer.com/article/10.1007%2Fs11262-018-01630) In 2017, an H7N8 avian influenza virus (AIV) was isolated from a domestic duck from a farm in Central China. Sequences analysis showed that this strain received its genes from H7, H1, H2, H3, H5, and H6 ... Yasuhara A, et al. Antigenic drift originating from changes to the lateral surface of the neuraminidase head of influenza A virus. Nat Microbiol. 2019 Mar 18.. Abstract submitted by kickingbird at Mar, 21, 2019 from Nat Microbiol. 2019 Mar 18. (via https://www.nature.com/articles/s41564-019-0401-1) Influenza viruses possess two surface glycoproteins, haemagglutinin and neuraminidase (NA). Although haemagglutinin plays a major role as a protective antigen, immunity to NA also contributes to protection. ... Hajam IA, Kim J, Lee JH. Intranasally administered polyethylenimine adjuvanted influenza M2 ectodomain induces partial protection against H9N2 influenza A virus infection in chickens. Vet Immunol Immunopathol. 2019 Mar;209:78-83.. Abstract submitted by kickingbird at Mar, 21, 2019 from Vet Immunol Immunopathol. 2019 Mar;209:78-83. (via https://www.sciencedirect.com/science/article/pii/S016524271) This study aimed to investigate whether intranasally coadministered four tandem copies of extracellular domains of M2 (M2e) and polyethyleneimine (PEI), a mucosal adjuvant, can protect chickens against ... Criado MF, et al. Efficacy of novel recombinant fowlpox vaccine against recent Mexican H7N3 highly pathogenic avian influenza virus. Vaccine. 2019 Mar 15. Abstract submitted by kickingbird at Mar, 21, 2019 from Vaccine. 2019 Mar 15 (via https://www.sciencedirect.com/science/article/pii/S0264410X1) Since 2012, H7N3 highly pathogenic avian influenza (HPAI) has produced negative economic and animal welfare impacts on poultry in central Mexico. In the present study, chickens were vaccinated with two ... Nannetti G, et al. Potent and broad-spectrum cycloheptathiophene-3-carboxamide compounds that target the PA-PB1 interaction of influenza virus RNA polymerase and possess a high barrier to drug resistance. Antiviral Res. 2019 Mar 15.. Abstract submitted by kickingbird at Mar, 21, 2019 from Antiviral Res. 2019 Mar 15. (via https://www.sciencedirect.com/science/article/pii/S016635421) Influenza viruses are major respiratory pathogens responsible for both seasonal epidemics and occasional pandemics worldwide. The current available treatment options have limited efficacy and thus the ... Dalcin D, Kwong JC. High-dose influenza vaccination. CMAJ. 2019 Mar 18;191(11):E313. Abstract submitted by kickingbird at Mar, 21, 2019 from CMAJ. 2019 Mar 18;191(11):E313 (via http://www.cmaj.ca/content/191/11/E313.long) High-dose trivalent inactivated influenza vaccine (HD-TIV) contains 60 μg of hemagglutinin per strain, whereas standard-dose vaccines (SD-TIV) contain 15 μg. Given the burden of influenza A subtype H3N2 ... Ma C, et al. Avian influenza A (H9N2) virus infections among poultry workers, swine workers, and the general population in Beijing, China, 2013-2016: A serological cohort study. Influenza Other Respir Viruses. 2019 Mar 18. Abstract submitted by kickingbird at Mar, 19, 2019 from Influenza Other Respir Viruses. 2019 Mar 18 (via https://onlinelibrary.wiley.com/doi/full/10.1111/irv.12641) BACKGROUND: Few studies have reported on the seroprevalence of antibodies against avian influenza A (H9N2) virus and the incidence of these infections in the northern China and among swine workers.METHODS: ... Abed Y, Fage C, Lagüe P, Carbonneau J, Papenburg J. Reduced Susceptibility to Neuraminidase Inhibitors in Influenza B Isolate, Canada. Emerg Infect Dis. 2019 Apr;25(4):838-840. Abstract submitted by kickingbird at Mar, 19, 2019 from Emerg Infect Dis. 2019 Apr;25(4):838-840 (via https://wwwnc.cdc.gov/eid/article/25/4/18-1554_article) We identified an influenza B isolate harboring a Gly407Ser neuraminidase substitution in an immunocompromised patient in Canada before antiviral therapy. This mutation mediated reduced susceptibility to ... Chen Y, Wen Y. Spatiotemporal Distributions and Dynamics of Human Infections with the A H7N9 Avian Influenza Virus. Comput Math Methods Med. 2019 Feb 7;2019:9248246. Abstract submitted by kickingbird at Mar, 19, 2019 from Comput Math Methods Med. 2019 Feb 7;2019:9248246 (via https://www.hindawi.com/journals/cmmm/2019/9248246/) In 2013 in mainland China, a novel avian influenza virus H7N9 began to infect humans and had aroused severe fatality in the infected humans, followed by the annual outbreaks. By methods of GIS and kriging ... Paget C, Trottein F. Mechanisms of Bacterial Superinfection Post-influenza: A Role for Unconventional T Cells. Front Immunol. 2019 Mar 1;10:336.. Abstract submitted by kickingbird at Mar, 19, 2019 from Front Immunol. 2019 Mar 1;10:336. (via https://www.frontiersin.org/articles/10.3389/fimmu.2019.0033) Despite the widespread application of vaccination programs and antiviral drug treatments, influenza viruses are still among the most harmful human pathogens. Indeed, influenza results in significant seasonal ... Pu Z, Yang J, Shen X, Irwin DM, Shen Y. Human-isolated H7N9 obtained internal genes from duck and human influenza viruses. J Infect. 2019 Mar 14.. Abstract submitted by kickingbird at Mar, 19, 2019 from J Infect. 2019 Mar 14. (via https://www.journalofinfection.com/article/S0163-4453(19)300) Recent studies in this journal revealed that some H7N9 viruses reassorted with duck AIVs, and then attained the ability to efficiently infect ducks.1,2 H7N9 AIVs have been endemic in chicken since their ... Tang W, Li X, Hu CH, Zhu C, Li Z, Wu D, Wang T, He. Isolation of H8N4 avian influenza virus from wild birds in Shanghai, China.. Acta Virol. 2019;63(1):121-125.. Abstract submitted by kickingbird at Mar, 19, 2019 from Acta Virol. 2019;63(1):121-125. (via https://www.ncbi.nlm.nih.gov/pubmed/30879322) The H8 subtype viruses are rarely isolated from wild ducks. Shanghai is one of the important wintering or stopover sites on the East Asia-Australia Migration Flyway. An influenza virus, subtype H8N4, was ... Moss R, et al. Anatomy of a seasonal influenza epidemic forecast. Commun Dis Intell (2018). 2019 Mar 15;43. Abstract submitted by kickingbird at Mar, 19, 2019 from Commun Dis Intell (2018). 2019 Mar 15;43 (via https://www.ncbi.nlm.nih.gov/pubmed/30879285) Bayesian methods have been used to predict the timing of infectious disease epidemics in various settings and for many infectious diseases, including seasonal influenza. But integrating these techniques ... Parvandeh S, et al. Multi-Level Model to Predict Antibody Response to Influenza Vaccine Using Gene Expression Interaction Network Feature Selection. Microorganisms. 2019 Mar 14;7(3).. Abstract submitted by kickingbird at Mar, 19, 2019 from Microorganisms. 2019 Mar 14;7(3). (via https://www.mdpi.com/2076-2607/7/3/79) Vaccination is an effective prevention of influenza infection. 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