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2024-11-26 8:44:40
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Barnard KN, Wasik BR, Alford-Lawrence BK, Hayward. Sequence dynamics of three influenza A virus strains grown in different MDCK cell lines, including those expressing different sialic acid receptors. J Evol Biol. 2021 Jun 11.  Abstract  
submitted by kickingbird at Jun, 12, 2021 from J Evol Biol. 2021 Jun 11 (via https://pubmed.ncbi.nlm.nih.gov/34114711/)
Viruses are often cultured in cell lines for research and vaccine development, and those often differ from the natural hosts or tissues. Cell lines can also differ in the presence of virus receptors, such ...

Ziebert F, Kuli? IM. How Influenza´s Spike Motor Works. Phys Rev Lett. 2021 May 28;126(21):218101.  Abstract  
submitted by kickingbird at Jun, 12, 2021 from Phys Rev Lett. 2021 May 28;126(21):218101 (via https://journals.aps.org/prl/abstract/10.1103/PhysRevLett.12)
While often believed to be a passive agent that merely exploits its host's metabolism, the influenza virus has recently been shown to actively move across glycan-coated surfaces. This form of enzymatically ...

Shingai M, Nomura N, Sekiya T, Ohno M, Fujikura D,. Potent priming by inactivated whole influenza virus particle vaccines is linked to viral RNA uptake into antigen presenting cells. Vaccine. 2021 Jun 2:S0264-410X(21)00660-5.  Abstract  
submitted by kickingbird at Jun, 8, 2021 from Vaccine. 2021 Jun 2:S0264-410X(21)00660-5 (via https://www.sciencedirect.com/science/article/pii/S0264410X2)
Current detergent or ether-disrupted split vaccines (SVs) for influenza do not always induce adequate immune responses, especially in young children. This contrasts with the whole virus particle vaccines ...

El-Sayed MM, Arafa AS, Abdelmagid M, Youssef AI. Epidemiological surveillance of H9N2 avian influenza virus infection among chickens in farms and backyards in Egypt 2015-2016. Vet World. 2021 Apr;14(4):949-955.  Abstract  
submitted by kickingbird at Jun, 7, 2021 from Vet World. 2021 Apr;14(4):949-955 (via http://www.veterinaryworld.org/Vol.14/April-2021/20.html)
Background and aim: LPAI H9N2 infection among the poultry population in Egypt constitutes an additional risk factor in the poultry industry. This study aimed to determine the prevalence of H9N2 avian influenza ...

Sasaki Y, Yoshino N, Okuwa T, Odagiri T, Satoh T,. A mouse monoclonal antibody against influenza C virus attenuates acetaminophen-induced liver injury in mice. Sci Rep. 2021 Jun 3;11(1):11816.  Abstract  
submitted by kickingbird at Jun, 7, 2021 from Sci Rep. 2021 Jun 3;11(1):11816 (via https://www.nature.com/articles/s41598-021-91251-x)
Molecular mimicry is one of the main processes for producing autoantibodies during infections. Although some autoantibodies are associated with autoimmune diseases, the functions of many autoantibodies ...

Zipfel CM, Colizza V, Bansal S. The missing season: The impacts of the COVID-19 pandemic on influenza. Vaccine. 2021 May 30:S0264-410X(21)00635-6.  Abstract  
submitted by kickingbird at Jun, 4, 2021 from Vaccine. 2021 May 30:S0264-410X(21)00635-6 (via https://www.sciencedirect.com/science/article/pii/S0264410X2)
Throughout the COVID-19 pandemic, many have worried that the additional burden of seasonal influenza would create a devastating scenario, resulting in overwhelmed healthcare capacities and further loss ...

Sato-Kaneko F, Yao S, Lao FS, Nan J, Shpigelman J,. Mitochondria-dependent synthetic small-molecule vaccine adjuvants for influenza virus infection. Proc Natl Acad Sci U S A. 2021 Jun 8;118(23):e2025.  Abstract  
submitted by kickingbird at Jun, 4, 2021 from Proc Natl Acad Sci U S A. 2021 Jun 8;118(23):e2025 (via https://www.pnas.org/content/118/23/e2025718118)
Vaccine adjuvants enhance and prolong pathogen-specific protective immune responses. Recent reports indicate that host factors-such as aging, pregnancy, and genetic polymorphisms-influence efficacies of ...

Guthmiller JJ, Han J, Li L, Freyn AW, Liu STH, Sto. First exposure to the pandemic H1N1 virus induced broadly neutralizing antibodies targeting hemagglutinin head epitopes. Sci Transl Med. 2021 Jun 2;13(596):eabg4535.  Abstract  
submitted by kickingbird at Jun, 4, 2021 from Sci Transl Med. 2021 Jun 2;13(596):eabg4535 (via https://stm.sciencemag.org/content/13/596/eabg4535)
Broadly neutralizing antibodies are critical for protection against both drifted and shifted influenza viruses. Here, we reveal that first exposure to the 2009 pandemic H1N1 influenza virus recalls memory ...

McCarthy KR, Von Holle TA, Sutherland LL, Oguin TH. Differential immune imprinting by influenza virus vaccination and infection in nonhuman primates. Proc Natl Acad Sci U S A. 2021 Jun 8;118(23):e2026.  Abstract  
submitted by kickingbird at Jun, 4, 2021 from Proc Natl Acad Sci U S A. 2021 Jun 8;118(23):e2026 (via https://www.pnas.org/content/118/23/e2026752118)
Immune memory of a first infection with influenza virus establishes a lasting imprint. Recall of that memory dominates the response to later infections or vaccinations by antigenically drifted strains. ...

Dionísio L, Medeiros F, Pequito M, Faustino-Rocha. Equine influenza: a comprehensive review from etiology to treatment. Anim Health Res Rev. 2021 Jun 2:1-16.  Abstract  
submitted by kickingbird at Jun, 4, 2021 from Anim Health Res Rev. 2021 Jun 2:1-16 (via https://www.cambridge.org/core/journals/animal-health-resear)
Influenza is an extremely contagious respiratory disease, which predominantly affects the upper respiratory tract. There are four types of influenza virus, and pigs and chickens are considered two key ...

Nelson SA, Dileepan T, Rasley A, Jenkins MK, Fisch. Intranasal nanoparticle vaccination elicits a persistent, polyfunctional CD4 T cell response in the murine lung specific for a highly conserved influenza antigen that are sufficient to mediate protect. J Virol. 2021 Jun 2:JVI0084121.  Abstract  
submitted by kickingbird at Jun, 4, 2021 from J Virol. 2021 Jun 2:JVI0084121 (via https://pubmed.ncbi.nlm.nih.gov/34076479/)
Lung-localized CD4 T cells play a critical role in the control of influenza virus infection and can provide broadly protective immunity. However, current influenza vaccination strategies primarily target ...

Elgendy EM, Arai Y, Kawashita N, Isobe A, Daidoji. Double mutations in the H9N2 avian influenza virus PB2 gene act cooperatively to increase viral host adaptation and replication for human infections. J Gen Virol. 2021 Jun;102(6).  Abstract  
submitted by kickingbird at Jun, 2, 2021 from J Gen Virol. 2021 Jun;102(6) (via https://www.microbiologyresearch.org/content/journal/jgv/10.)
Avian H9N2 influenza viruses in East Asia are genetically diversified and multiple genotypes (A-W) have been established in poultry. Genotype S strains are currently the most prevalent strains, have caused ...

Goldhill DH, Yan A, Frise R, Zhou J, Shelley J, Ga. Favipiravir-resistant influenza A virus shows potential for transmission. PLoS Pathog. 2021 Jun 1;17(6):e1008937.  Abstract  
submitted by kickingbird at Jun, 2, 2021 from PLoS Pathog. 2021 Jun 1;17(6):e1008937 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Favipiravir is a nucleoside analogue which has been licensed to treat influenza in the event of a new pandemic. We previously described a favipiravir resistant influenza A virus generated by in vitro passage ...

Tamura H, Kuraoka S, Hidaka Y, Nagata H, Furuie K,. A Case of Nephrotic Syndrome that Resolved with Influenza B Infection. Case Rep Nephrol Dial. 2021 Apr 21;11(1):103-109.  Abstract  
submitted by kickingbird at Jun, 1, 2021 from Case Rep Nephrol Dial. 2021 Apr 21;11(1):103-109 (via https://www.karger.com/Article/FullText/515062)
It has been postulated that measles virus infection is associated with remission of idiopathic nephrotic syndrome (INS) in childhood. There are few reports on the correlation of INS remission with other ...

Rainey JJ, Koch DB, Chen YH, Yuan J, Cheriyadat A. Using video-analysis technology to estimate social mixing and simulate influenza transmission at a mass gathering. Epidemics. 2021 May 12;36:100466.  Abstract  
submitted by kickingbird at May, 31, 2021 from Epidemics. 2021 May 12;36:100466 (via https://www.sciencedirect.com/science/article/pii/S175543652)
Mass gatherings create settings conducive to infectious disease transmission. Empirical data to model infectious disease transmission at mass gatherings are limited. Video-analysis technology could be ...

Wang Z, Yu J, Sheng Z, Hause BM, Li F, Kaushik RS,. Functional study of a role of N-terminal HA stem region of swine influenza A virus in virus replication. Vet Microbiol. 2021 May 25;258:109132.  Abstract  
submitted by kickingbird at May, 31, 2021 from Vet Microbiol. 2021 May 25;258:109132 (via https://www.sciencedirect.com/science/article/pii/S037811352)
Swine influenza A virus (SIV) is both a pathogen of economic significance to the swine industry and a potential zoonotic organism that may be transmitted to humans. We described here the detailed characterization ...

Chepkwony S, Parys A, Vandoorn E, Stadejek W, Xie. Genetic and antigenic evolution of H1 swine influenza A viruses isolated in Belgium and the Netherlands from 2014 through 2019. Sci Rep. 2021 May 28;11(1):11276.  Abstract  
submitted by kickingbird at May, 31, 2021 from Sci Rep. 2021 May 28;11(1):11276 (via https://www.nature.com/articles/s41598-021-90512-z)
Surveillance of swine influenza A viruses (swIAV) allows timely detection and identification of new variants with potential zoonotic risks. In this study, we aimed to identify swIAV subtypes that circulated ...

Sia ZR, He X, Zhang A, Ang JC, Shao S, Seffouh A,. A liposome-displayed hemagglutinin vaccine platform protects mice and ferrets from heterologous influenza virus challenge. Proc Natl Acad Sci U S A. 2021 Jun 1;118(22):e2025.  Abstract  
submitted by kickingbird at May, 31, 2021 from Proc Natl Acad Sci U S A. 2021 Jun 1;118(22):e2025 (via https://www.pnas.org/content/118/22/e2025759118)
Recombinant influenza virus vaccines based on hemagglutinin (HA) hold the potential to accelerate production timelines and improve efficacy relative to traditional egg-based platforms. Here, we assess ...

Wen F, Yang J, Guo J, Wang C, Cheng Q, Tang Z, Luo. Genetic characterization of an H5N6 avian influenza virus with multiple origins from a chicken in southern China, October 2019. BMC Vet Res. 2021 May 28;17(1):200.  Abstract  
submitted by kickingbird at May, 31, 2021 from BMC Vet Res. 2021 May 28;17(1):200 (via https://bmcvetres.biomedcentral.com/articles/10.1186/s12917-)
Background: Highly pathogenic avian influenza viruses (HPAIVs) of H5 subtype pose a great threat to the poultry industry and human health. In recent years, H5N6 subtype has rapidly replaced H5N1 as the ...

Yang J, Huang M, Qiao S, Zhang P, Teng Q, Li X, Li. Replication and virulence of chimeric bat influenza viruses in mammalian and avian cells and in mice. Microb Pathog. 2021 May 24:104992.  Abstract  
submitted by kickingbird at May, 31, 2021 from Microb Pathog. 2021 May 24:104992 (via https://www.sciencedirect.com/science/article/abs/pii/S08824)
Previous studies have shown that chimeric bat influenza viruses can be generated by reverse genetic system. However, the roles of the surface or internal genes of chimeric bat influenza viruses in viral ...

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