Ivan FX, Kwoh CK. Rule-based meta-analysis reveals the major role of PB2 in influencing influenza A virus virulence in mice. BMC Genomics. 2019 Dec 24. Abstract
submitted by kickingbird at Dec, 27, 2019 from BMC Genomics. 2019 Dec 24 (via https://bmcgenomics.biomedcentral.com/articles/10.1186/s1286)
BACKGROUND: Influenza A virus (IAV) poses threats to human health and life. Many individual studies have been carried out in mice to uncover the viral factors responsible for the virulence of IAV infections. ... Lina L, et al. Adaptive amino acid substitutions enable transmission of an H9N2 avian influenza virus in guinea pigs. Sci Rep. 2019 Dec 24;9(1):19734. Abstract
submitted by kickingbird at Dec, 27, 2019 from Sci Rep. 2019 Dec 24;9(1):19734 (via https://www.nature.com/articles/s41598-019-56122-6)
H9N2 is the most prevalent low pathogenic avian influenza virus (LPAIV) in domestic poultry in the world. Two distinct H9N2 poultry lineages, G1-like (A/quail/Hong Kong/G1/97) and Y280-like (A/Duck/Hong ... Galli C, et al. In-depth phylogenetic analysis of the hemagglutinin gene of influenza A(H3N2) viruses circulating during the 2016-2017 season revealed egg-adaptive mutations of vaccine strains. Expert Rev Vaccines. 2019 Dec 25.. Abstract
submitted by kickingbird at Dec, 27, 2019 from Expert Rev Vaccines. 2019 Dec 25. (via https://www.tandfonline.com/doi/abs/10.1080/14760584.2020.17)
Objectives: The authors conducted an in-depth phylogenetic analysis of the hemagglutinin (HA) gene of A(H3N2) identified during the 2016-2017 season to compare the circulating strains with both the egg-derived ... Zost SJ, et al. Identification of Antibodies Targeting the H3N2 Hemagglutinin Receptor Binding Site following Vaccination of Humans. Cell Rep. 2019 Dec 24;29(13):4460-4470.e8.. Abstract
submitted by kickingbird at Dec, 27, 2019 from Cell Rep. 2019 Dec 24;29(13):4460-4470.e8. (via https://www.cell.com/cell-reports/fulltext/S2211-1247(19)315)
Antibodies targeting the receptor binding site (RBS) of the influenza virus hemagglutinin (HA) protein are usually not broadly reactive because their footprints are typically large and extend to nearby ... Lin X, Yu S, Ren P, Sun X, Jin M. Human microRNA-30 inhibits influenza virus infection by suppressing the expression of SOCS1, SOCS3, and NEDD4. Cell Microbiol. 2019 Dec 26:e13150.. Abstract
submitted by kickingbird at Dec, 27, 2019 from Cell Microbiol. 2019 Dec 26:e13150. (via https://onlinelibrary.wiley.com/doi/abs/10.1111/cmi.13150)
Influenza A virus (IAV) has evolved multiple mechanisms to compromise type I interferon (IFN) responses. The antiviral function of IFN is mainly exerted by activating the JAK/STAT signalling and subsequently ... Honce R, et al. Influenza in High-Risk Hosts-Lessons Learned from Animal Models. Cold Spring Harb Perspect Med. 2019 Dec 23.. Full Text
submitted by kickingbird at Dec, 26, 2019 from Cold Spring Harb Perspect Med. 2019 Dec 23. (via http://perspectivesinmedicine.cshlp.org/content/early/2019/1)
Factoring significantly into the global burden of influenza disease are high-risk populations that suffer the bulk of infections. Classically, the very young, very old, and pregnant women have been identified ... Ciminski K, Schwemmle M. Bat-Borne Influenza A Viruses: An Awakening. Cold Spring Harb Perspect Med. 2019 Dec 23.. Full Text
submitted by kickingbird at Dec, 26, 2019 from Cold Spring Harb Perspect Med. 2019 Dec 23. (via http://perspectivesinmedicine.cshlp.org/content/early/2019/1)
Influenza A viruses (IAVs) originating from aquatic waterfowl recurrently cross interspecies barriers, which is greatly facilitated by utilizing cell surface-exposed monosaccharide sialic acids located ... Fodor E, Te Velthuis AJW. Structure and Function of the Influenza Virus Transcription and Replication Machinery. Cold Spring Harb Perspect Med. 2019 Dec 23.. Full Text
submitted by kickingbird at Dec, 26, 2019 from Cold Spring Harb Perspect Med. 2019 Dec 23. (via http://perspectivesinmedicine.cshlp.org/content/early/2019/1)
Transcription and replication of the influenza virus RNA genome is catalyzed by the viral heterotrimeric RNA-dependent RNA polymerase in the context of viral ribonucleoprotein (vRNP) complexes. Atomic ... Belser JA, Pulit-Penaloza JA, Maines TR. Ferreting Out Influenza Virus Pathogenicity and Transmissibility: Past and Future Risk Assessments in the Ferret Model. Cold Spring Harb Perspect Med. 2019 Dec 23.. Full Text
submitted by kickingbird at Dec, 26, 2019 from Cold Spring Harb Perspect Med. 2019 Dec 23. (via http://perspectivesinmedicine.cshlp.org/content/early/2019/1)
As influenza A viruses continue to jump species barriers, data generated in the ferret model to assess influenza virus pathogenicity, transmissibility, and tropism of these novel strains continues to inform ... Ludwig S, Hrincius ER, Boergeling Y. The Two Sides of the Same Coin-Influenza Virus and Intracellular Signal Transduction. Cold Spring Harb Perspect Med. 2019 Dec 23. Full Text
submitted by kickingbird at Dec, 26, 2019 from Cold Spring Harb Perspect Med. 2019 Dec 23 (via http://perspectivesinmedicine.cshlp.org/content/early/2019/1)
Cells respond to extracellular agents by activation of intracellular signaling pathways. Viruses can be regarded as such agents, leading to a firework of signaling inside the cell, primarily induced by ... Wu NC, Wilson IA. Influenza Hemagglutinin Structures and Antibody Recognition. Cold Spring Harb Perspect Med. 2019 Dec 23. Full Text
submitted by kickingbird at Dec, 26, 2019 from Cold Spring Harb Perspect Med. 2019 Dec 23 (via http://perspectivesinmedicine.cshlp.org/content/early/2019/1)
Hemagglutinin (HA) is most abundant glycoprotein on the influenza virus surface. Influenza HA promotes viral entry by engaging the receptor and mediating virus-host membrane fusion. At the same time, HA ... Wille M, Holmes EC. The Ecology and Evolution of Influenza Viruses. Cold Spring Harb Perspect Med. 2019 Dec 23. Full Text
submitted by kickingbird at Dec, 26, 2019 from Cold Spring Harb Perspect Med. 2019 Dec 23 (via http://perspectivesinmedicine.cshlp.org/content/early/2019/1)
The patterns and processes of influenza virus evolution are of fundamental importance, underpinning such traits as the propensity to emerge in new host species and the ability to rapidly generate antigenic ... Johnson KEE, Ghedin E. Quantifying between-Host Transmission in Influenza Virus Infections. Cold Spring Harb Perspect Med. 2019 Dec 23.. Full Text
submitted by kickingbird at Dec, 26, 2019 from Cold Spring Harb Perspect Med. 2019 Dec 23. (via http://perspectivesinmedicine.cshlp.org/content/early/2019/1)
The error-prone replication and life cycle of influenza virus generate a diverse set of genetic variants. Transmission between hosts strictly limits both the number of virus particles and the genetic diversity ... Gadalla MR, Abrami L, van der Goot FG, Veit M. Hemagglutinin of Influenza A, but not of Influenza B and C viruses is acylated by ZDHHC2, 8, 15 and 20. Biochem J. 2019 Dec 24. Abstract
submitted by kickingbird at Dec, 26, 2019 from Biochem J. 2019 Dec 24 (via https://portlandpress.com/biochemj/article/doi/10.1042/BCJ20)
Hemagglutinin (HA), a glycoprotein of Influenza A viruses and its proton-channel M2 are site-specifically modified with fatty acids. Whereas two cysteines in the short cytoplasmic tail of HA contain only ... Baranovskaya I, et al. Changes in RNA secondary structure affect NS1 protein expression during early stage influenza virus infection. Virol J. 2019 Dec 21;16(1):162.. Abstract
submitted by kickingbird at Dec, 23, 2019 from Virol J. 2019 Dec 21;16(1):162. (via https://virologyj.biomedcentral.com/articles/10.1186/s12985-)
RNA secondary structures play a key role in splicing, gene expression, microRNA biogenesis, RNA editing, and other biological processes. The importance of RNA structures has been demonstrated in the life ... Yao L, et al. Persistence of H7N9 virus antibody response 2 years after infection. Influenza Other Respir Viruses. 2019 Dec 19.. Abstract
submitted by kickingbird at Dec, 21, 2019 from Influenza Other Respir Viruses. 2019 Dec 19. (via https://onlinelibrary.wiley.com/doi/full/10.1111/irv.12702)
We measured antibodies against H7N9 virus 2 years after infection in 14 patients who were infected during October 2016-September 2017. Approximately 2 years after infection, antibody titers ≥10 were detectable ... Jiang W, et al. Antigenic Variant of Highly Pathogenic Avian Influenza A(H7N9) Virus, China, 2019. Emerg Infect Dis. 2020 Feb 17;26(2). Abstract
submitted by kickingbird at Dec, 21, 2019 from Emerg Infect Dis. 2020 Feb 17;26(2) (via https://wwwnc.cdc.gov/eid/article/26/2/19-1105_article)
In China, influenza A(H7N9) virus appeared in 2013, then mutated into a highly pathogenic virus, causing outbreaks among poultry and cases in humans. Since September 2017, extensive use of the corresponding ... Murakami S, et al. Influenza D Virus of New Phylogenetic Lineage, Japan. Emerg Infect Dis. 2020 Jan;26(1):168-171.. Abstract
submitted by kickingbird at Dec, 21, 2019 from Emerg Infect Dis. 2020 Jan;26(1):168-171. (via https://wwwnc.cdc.gov/eid/article/26/1/19-1092_article)
Influenza D virus (IDV) can potentially cause respiratory diseases in livestock. We isolated a new IDV strain from diseased cattle in Japan; this strain is phylogenetically and antigenically distinguished ... Tepper V, et al. Influenza A/H4N2 mallard infection experiments further indicate zanamivir as less prone to induce environmental resistance development than oseltamivir. J Gen Virol. 2019 Dec 19. Abstract
submitted by kickingbird at Dec, 21, 2019 from J Gen Virol. 2019 Dec 19 (via https://www.microbiologyresearch.org/content/journal/jgv/10.)
Neuraminidase inhibitors (NAIs) are the gold standard treatment for influenza A virus (IAV). Oseltamivir is mostly used, followed by zanamivir (ZA). NAIs are not readily degraded in conventional wastewater ... Jia R, Liu S, Xu J, Liang X. IL16 deficiency enhances Th1 and cytotoxic T lymphocyte response against influenza A virus infection. Biosci Trends. 2019 Dec 18. Abstract
submitted by kickingbird at Dec, 21, 2019 from Biosci Trends. 2019 Dec 18 (via https://www.jstage.jst.go.jp/article/bst/advpub/0/advpub_201)
Influenza A virus (IAV) is the major cause of seasonal epidemics and flu outbreaks worldwide. Given that interleukin 16 (IL16) can regulate T cell function and is one of the signature markers for virus ... 5328 items, 20/Page, Page[94/267][|<<] [|<] [91] [92] [93] [94] [95] [96] [97] [98] [99] [100] [>|] [>>|] |
Related Pages:
Browse by Category
Learn about the flu news, articles, events and more
Subscribe to the weekly F.I.C newsletter!
|
- 
