Van den Hoecke S, Ballegeer M, Vrancken B, Deng L,. In Vivo Therapy with M2e-Specific IgG Selects for an Influenza A Virus Mutant with Delayed Matrix Protein 2 Expression. mBio. 2021 Jul 13:e0074521. Abstract
submitted by kickingbird at Jul, 16, 2021 from mBio. 2021 Jul 13:e0074521 (via https://journals.asm.org/doi/10.1128/mBio.00745-21)
The ectodomain of matrix protein 2 (M2e) of influenza A viruses is a universal influenza A vaccine candidate. Here, we report potential evasion strategies of influenza A viruses under in vivo passive anti-M2e ... Vieira MC, Donato CM, Arevalo P, Rimmelzwaan GF, W. Lineage-specific protection and immune imprinting shape the age distributions of influenza B cases. Nat Commun. 2021 Jul 14;12(1):4313. Abstract
submitted by kickingbird at Jul, 16, 2021 from Nat Commun. 2021 Jul 14;12(1):4313 (via https://www.nature.com/articles/s41467-021-24566-y)
How a history of influenza virus infections contributes to protection is not fully understood, but such protection might explain the contrasting age distributions of cases of the two lineages of influenza ... Xiong J, Zhou H, Fan L, Zhu G, Li Y, Chen G, Zhang. Emerging highly pathogenic avian influenza (H5N8) virus in migratory birds in Central China, 2020. Emerg Microbes Infect. 2021 Jul 14:1-35. Abstract
submitted by kickingbird at Jul, 15, 2021 from Emerg Microbes Infect. 2021 Jul 14:1-35 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2021.1)
Eleven highly pathogenic avian influenza H5N8 viruses (clade 2.3.4.4b) were detected in migratory birds in Central China between November and December 2020, which were highly homologous to strains isolated ... Sorokin EV, Tsareva TR, Rudneva IA, Timofeev BI, L. Monoclonal antibodies to hemagglutinin of influenza A/H7N3 virus (Orthomyxoviridae: Alphainfluenzavirus: Influenza A virus). Vopr Virusol. 2021 Jul 9;66(3):189-197. Abstract
submitted by kickingbird at Jul, 15, 2021 from Vopr Virusol. 2021 Jul 9;66(3):189-197 (via https://virusjour.elpub.ru/jour/article/view/521)
Introduction: Variants of influenza virus A/H7 have the same high pandemic potential as A/H5. However, the information about the antigenic structure of H7 hemagglutinin (НА) is considerably inferior in ... Kim WH, Cho S. Estimation of the Basic Reproduction Numbers of the Subtypes H5N1, H5N8, and H5N6 During the Highly Pathogenic Avian Influenza Epidemic Spread Between Farms. Front Vet Sci. 2021 Jun 24;8:597630.. Abstract
submitted by kickingbird at Jul, 13, 2021 from Front Vet Sci. 2021 Jun 24;8:597630. (via https://www.frontiersin.org/articles/10.3389/fvets.2021.5976)
It is important to understand pathogen transmissibility in a population to establish an effective disease prevention policy. The basic reproduction number (R 0) is an epidemiologic parameter for understanding ... Guo X, Qi X, Cui L, Ge Y, Yu H, Zhu X, Chen Y, Shi. Complete Genome Sequence of a Novel Reassortant Avian Influenza H9N9 Virus Isolated from Chicken in Eastern China. Genome Announc. 2014 Sep 18;2(5):e00932-14. Abstract
submitted by kickingbird at Jul, 12, 2021 from Genome Announc. 2014 Sep 18;2(5):e00932-14 (via https://journals.asm.org/doi/10.1128/genomeA.00932-14)
The genome sequence of the strain A/chicken/Changzhou/C08/2013 (H9N9) shows that the hemagglutinin (HA) genes of this strain are closely related to those of the strain A/chicken/Shanghai/1107/2013 (H9N2) ... Hayashi H, Isoda N, Bazarragchaa E, Nomura N, Mats. Potency of an Inactivated Influenza Vaccine against a Challenge with A/Swine/Missouri/A01727926/2015 (H4N6) in Mice for Pandemic Preparedness. Vaccines (Basel). 2020 Dec 16;8(4):768.. Abstract
submitted by kickingbird at Jul, 12, 2021 from Vaccines (Basel). 2020 Dec 16;8(4):768. (via https://www.mdpi.com/2076-393X/8/4/768)
H4 influenza viruses have been isolated from birds across the world. In recent years, an H4 influenza virus infection has been confirmed in pigs. Pigs play an important role in the transmission of influenza ... ostnikova Y, Treshchalina A, Boravleva E, Gambarya. Diversity and Reassortment Rate of Influenza A Viruses in Wild Ducks and Gulls. Viruses. 2021 May 27;13(6):1010. Abstract
submitted by kickingbird at Jul, 12, 2021 from Viruses. 2021 May 27;13(6):1010 (via https://www.mdpi.com/1999-4915/13/6/1010)
Influenza A viruses (IAVs) evolve via point mutations and reassortment of viral gene segments. The patterns of reassortment in different host species differ considerably. We investigated the genetic diversity ... Nakano M, Sugita Y, Kodera N, Miyamoto S, Muramoto. Ultrastructure of influenza virus ribonucleoprotein complexes during viral RNA synthesis. Commun Biol. 2021 Jul 9;4(1):858. Abstract
submitted by kickingbird at Jul, 12, 2021 from Commun Biol. 2021 Jul 9;4(1):858 (via https://www.nature.com/articles/s42003-021-02388-4)
The single-stranded, negative-sense, viral genomic RNA (vRNA) of influenza A virus is encapsidated by viral nucleoproteins (NPs) and an RNA polymerase to form a ribonucleoprotein complex (vRNP) with a ... He D, Gu J, Gu M, Wu H, Li J, Zhan T, Chen Y, Xu N. Genetic and antigenic diversity of H7N9 highly pathogenic avian influenza virus in China from 2017 to 2019. Infect Genet Evol. 2021 Jul 6:104993. Abstract
submitted by kickingbird at Jul, 12, 2021 from Infect Genet Evol. 2021 Jul 6:104993 (via https://www.sciencedirect.com/science/article/abs/pii/S15671)
Avian influenza virus (AIV) H7N9 that emerged in 2013 in eastern China is a novel zoonotic agent mainly circulating in poultry without clinical signs but causing severe disease with high fatality in humans ... Ichimiya T, Okamatsu M, Kinoshita T, Kobayashi D,. Sulfated glycans containing NeuAcα2-3Gal facilitate the propagation of human H1N1 influenza A viruses in eggs. Virology. 2021 Jun 25;562:29-39. Abstract
submitted by kickingbird at Jul, 12, 2021 from Virology. 2021 Jun 25;562:29-39 (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
When human influenza viruses are isolated and passaged in chicken embryos, variants with amino acid substitutions around the receptor binding site of hemagglutinin (HA) are selected; however, the mechanisms ... Wang Y, Yuan C, Xu X, Chong TH, Zhang L, Cheung PP. The mechanism of action of T-705 as a unique delayed chain terminator on influenza viral polymerase transcription. Biophys Chem. 2021 Jun 25;277:106652. Abstract
submitted by kickingbird at Jul, 10, 2021 from Biophys Chem. 2021 Jun 25;277:106652 (via https://www.sciencedirect.com/science/article/abs/pii/S03014)
Favipiravir (T-705) has been developed as a potent anti-influenza drug and exhibited a strong inhibition effect against a broad spectrum of RNA viruses. Its active form, ribofuranosyl-triphosphate (T-705-RTP), ... Leyson CM, Youk S, Ferreira HL, Suarez DL, Pantin-. Multiple gene segments are associated with enhanced virulence of clade 2.3.4.4 H5N8 highly pathogenic avian influenza virus in mallards. J Virol. 2021 Jul 7:JVI0095521. Abstract
submitted by kickingbird at Jul, 8, 2021 from J Virol. 2021 Jul 7:JVI0095521 (via https://journals.asm.org/doi/10.1128/JVI.00955-21)
Highly pathogenic avian influenza (HPAI) viruses from the H5Nx Goose/Guangdong/96 lineage continue to cause outbreaks in domestic and wild bird populations. Two distinct genetic groups of H5N8 HPAI viruses, ... Yoo DS, Chun B, Min KD, Lim JS, Moon OK, Lee KN. Elucidating the Local Transmission Dynamics of Highly Pathogenic Avian Influenza H5N6 in the Republic of Korea by Integrating Phylogenetic Information. Pathogens. 2021 Jun 2;10(6):691. Abstract
submitted by kickingbird at Jul, 4, 2021 from Pathogens. 2021 Jun 2;10(6):691 (via https://www.mdpi.com/2076-0817/10/6/691)
Highly pathogenic avian influenza (HPAI) virus is one of the most virulent and infectious pathogens of poultry. As a response to HPAI epidemics, veterinary authorities implement preemptive depopulation ... Liang Y, Krog JS, Ryt-Hansen P, Pedersen AG, Kvisg. Molecular Characterization of Highly Pathogenic Avian Influenza Viruses H5N6 Detected in Denmark in 2018-2019. Viruses. 2021 Jun 2;13(6):1052. Abstract
submitted by kickingbird at Jul, 4, 2021 from Viruses. 2021 Jun 2;13(6):1052 (via https://www.mdpi.com/1999-4915/13/6/1052)
Beginning in late 2017, highly pathogenic avian influenza (HPAI) H5N6 viruses caused outbreaks in wild birds and poultry in several European countries. H5N6 viruses were detected in 43 wild birds found ... Chrzastek K, Segovia K, Torchetti M, Killian ML, P. Virus Adaptation Following Experimental Infection of Chickens with a Domestic Duck Low Pathogenic Avian Influenza Isolate from the 2017 USA H7N9 Outbreak Identifies Polymorphic Mutations in Multiple G. Viruses. 2021 Jun 18;13(6):1166. Abstract
submitted by kickingbird at Jul, 4, 2021 from Viruses. 2021 Jun 18;13(6):1166 (via https://www.mdpi.com/1999-4915/13/6/1166)
In March 2017, highly pathogenic (HP) and low pathogenic (LP) avian influenza virus (AIV) subtype H7N9 were detected from poultry farms and backyard birds in several states in the southeast United States. ... Soh YQS, Malone KD, Eguia RT, Bloom JD. Comprehensive Profiling of Mutations to Influenza Virus PB2 That Confer Resistance to the Cap-Binding Inhibitor Pimodivir. Viruses. 2021 Jun 22;13(7):1196. Abstract
submitted by kickingbird at Jul, 4, 2021 from Viruses. 2021 Jun 22;13(7):1196 (via https://www.mdpi.com/1999-4915/13/7/1196)
Antivirals are used not only in the current treatment of influenza but are also stockpiled as a first line of defense against novel influenza strains for which vaccines have yet to be developed. Identifying ... Xiao Y, Zhang W, Pan M, Bauer DLV, Bi Y, Cao M, Fo. A synergistic effect between 3´ terminal noncoding and adjacent coding regions of influenza A virus HA segment on template preference. J Virol. 2021 Jun 30:JVI0087821. Abstract
submitted by kickingbird at Jul, 2, 2021 from J Virol. 2021 Jun 30:JVI0087821 (via https://journals.asm.org/doi/10.1128/JVI.00878-21)
The influenza A virus genome is comprised of eight single-stranded negative-sense viral RNA (vRNA) segments. Each of the eight vRNA segments contains segment-specific nonconserved noncoding regions (NCRs) ... Yu J, Huang C, Sheng Z, Wang Z, Li F, Wang D. Identification of One Critical Amino Acid Residue of the Nucleoprotein as a Determinant for in vitro Viral Replication Fitness of Influenza D Virus. J Virol. 2021 Jun 30:JVI0097121. Abstract
submitted by kickingbird at Jul, 2, 2021 from J Virol. 2021 Jun 30:JVI0097121 (via https://journals.asm.org/doi/10.1128/JVI.00971-21)
The newly identified influenza D virus (IDV) of the Orthomyxoviridae family has a wide host range with broad geographical distribution. Despite the first appearance in U.S. pig herds in 2011, subsequent ... Wang Y, Niu S, Zhang B, Yang C, Zhou Z. The whole genome analysis for the first human infection with H10N3 influenza virus in China. J Infect. 2021 Jun 27:S0163-4453(21)00318-2. Abstract
submitted by kickingbird at Jul, 2, 2021 from J Infect. 2021 Jun 27:S0163-4453(21)00318-2 (via https://www.journalofinfection.com/article/S0163-4453(21)003)
A strain of H10N3 influenza virus, A/Jiangsu/428/2021/H10N3, was isolated from patient in Jiangsu province, eastern China. Phylogenetic analysis illustrated this human H10N3 virus was a low pathogenic ... 5584 items, 20/Page, Page[75/280][|<<] [|<] [71] [72] [73] [74] [75] [76] [77] [78] [79] [80] [>|] [>>|] |
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