Yang F, Xiao Y, Liu F, Yao H, Wu N, Wu H. Molecular Characterization and Antigenic analysis of reassortant H9N2 subtype avian influenza viruses in Eastern China in 2016. Virus Res. 2021 Sep 21:198577.. Abstract
submitted by kickingbird at Sep, 26, 2021 from Virus Res. 2021 Sep 21:198577. (via https://pubmed.ncbi.nlm.nih.gov/34560182/)
H9N2 avian influenza viruses (AIVs) can cause respiratory symptoms and decrease the egg production. Additionally, H9N2 AIVs can provide internal genes for reassortment with other subtypes. During the monitoring ... West J, R?der J, Matrosovich T, Beicht J, Baumann. Characterization of changes in the hemagglutinin that accompanied the emergence of H3N2/1968 pandemic influenza viruses. PLoS Pathog. 2021 Sep 23;17(9):e1009566.. Abstract
submitted by kickingbird at Sep, 26, 2021 from PLoS Pathog. 2021 Sep 23;17(9):e1009566. (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
The hemagglutinin (HA) of A/H3N2 pandemic influenza viruses (IAVs) of 1968 differed from its inferred avian precursor by eight amino acid substitutions. To determine their phenotypic effects, we studied ... Song W, Huang X, Guan W, Chen P, Wang P, Zheng M,. Multiple basic amino acids in the cleavage site of H7N9 hemagglutinin contribute to high virulence in mice. J Thorac Dis. 2021 Aug;13(8):4650-4660. Abstract
submitted by kickingbird at Sep, 22, 2021 from J Thorac Dis. 2021 Aug;13(8):4650-4660 (via https://jtd.amegroups.com/article/view/54443/html)
Background: Avian influenza A (H7N9) virus has caused more than 1,500 cases of human infection since its emergence in early 2013. Displaying little or no pathogenicity in poultry, but a 40% case-fatality ... Liu K, Ding P, Pei Y, Gao R, Han W, Zheng H, Ji Z,. Emergence of a novel reassortant avian influenza virus (H10N3) in Eastern China with high pathogenicity and respiratory droplet transmissibility to mammals. Sci China Life Sci. 2021 Sep 17. Abstract
submitted by kickingbird at Sep, 22, 2021 from Sci China Life Sci. 2021 Sep 17 (via https://link.springer.com/article/10.1007%2Fs11427-020-1981-)
Decades have passed since the first discovery of H10-subtype avian influenza virus (AIV) in chickens in 1949, and it has been detected in many species including mammals such as minks, pigs, seals and humans. ... Le TB, Le VP, Lee JE, Kang JA, Trinh TBN, Lee HW,. Reassortant Highly Pathogenic H5N6 Avian Influenza Virus Containing Low Pathogenic Viral Genes in a Local Live Poultry Market, Vietnam. Curr Microbiol. 2021 Sep 21. Abstract
submitted by kickingbird at Sep, 22, 2021 from Curr Microbiol. 2021 Sep 21 (via https://link.springer.com/article/10.1007%2Fs00284-021-02661)
Sites of live poultry trade and marketing are hot spots for avian influenza virus (AIV) transmission. We conducted active surveillance at a local live poultry market (LPM) in northern Vietnamese provinces ... Broszeit F, van Beek RJ, Unione L, Bestebroer TM,. Glycan remodeled erythrocytes facilitate antigenic characterization of recent A/H3N2 influenza viruses. Nat Commun. 2021 Sep 14;12(1):5449. Abstract
submitted by kickingbird at Sep, 16, 2021 from Nat Commun. 2021 Sep 14;12(1):5449 (via https://www.nature.com/articles/s41467-021-25713-1)
During circulation in humans and natural selection to escape antibody recognition for decades, A/H3N2 influenza viruses emerged with altered receptor specificities. These viruses lost the ability to agglutinate ... Ferenczi M, Beckmann C, Klaassen M. Rainfall driven and wild-bird mediated avian influenza virus outbreaks in Australian poultry. BMC Vet Res. 2021 Sep 14;17(1):306.. Abstract
submitted by kickingbird at Sep, 16, 2021 from BMC Vet Res. 2021 Sep 14;17(1):306. (via https://bmcvetres.biomedcentral.com/articles/10.1186/s12917-)
Globally, outbreaks of Avian Influenza Virus (AIV) in poultry continue to burden economies and endanger human, livestock and wildlife health. Wild waterbirds are often identified as possible sources for ... Staller E, Sheppard CM, Baillon L, Frise R, Peacoc. A natural variant in ANP32B impairs influenza virus replication in human cells. J Gen Virol. 2021 Sep;102(9). Abstract
submitted by kickingbird at Sep, 16, 2021 from J Gen Virol. 2021 Sep;102(9) (via https://www.microbiologyresearch.org/content/journal/jgv/10.)
Viruses require host factors to support their replication, and genetic variation in such factors can affect susceptibility to infectious disease. Influenza virus replication in human cells relies on ANP32 ... Si L, Bai H, Oh CY, Jin L, Prantil-Baun R, Ingber. Clinically Relevant Influenza Virus Evolution Reconstituted in a Human Lung Airway-on-a-Chip. Microbiol Spectr. 2021 Sep 15:e0025721. Abstract
submitted by kickingbird at Sep, 16, 2021 from Microbiol Spectr. 2021 Sep 15:e0025721 (via https://journals.asm.org/doi/10.1128/Spectrum.00257-21)
Human-to-human transmission of viruses, such as influenza viruses and coronaviruses, can promote virus evolution and the emergence of new strains with increased potential for creating pandemics. Clinical ... Villalón-Letelier F, Brooks AG, Londrigan SL. MARCH8 Restricts Influenza A Virus Infectivity but Does Not Downregulate Viral Glycoprotein Expression at the Surface of Infected Cells. mBio. 2021 Sep 14:e0148421. Abstract
submitted by kickingbird at Sep, 15, 2021 from mBio. 2021 Sep 14:e0148421 (via https://journals.asm.org/doi/10.1128/mBio.01484-21)
Membrane-associated RING-CH8 (MARCH8) impairs the cell surface expression of envelope glycoproteins from different viruses, reducing their incorporation into virions. Using stable cell lines with inducible ... Zhang L, Zheng X, Li J, Wang G, Hu Z, Chen Y, Wang. Long noncoding RNA#45 exerts broad inhibitory effect on influenza a virus replication via its stem ring arms. Virulence. 2021 Dec;12(1):2443-2460. Abstract
submitted by kickingbird at Sep, 15, 2021 from Virulence. 2021 Dec;12(1):2443-2460 (via https://www.tandfonline.com/doi/full/10.1080/21505594.2021.1)
A growing body of evidence suggests the pivotal role of long non-coding RNA (lncRNA) in influenza virus infection. Based on next-generation sequencing, we previously demonstrated that Lnc45 was distinctively ... Ren L, Zhang W, Zhang J, Zhang J, Zhang H, Zhu Y,. Influenza A Virus (H1N1) Infection Induces Glycolysis to Facilitate Viral Replication. Virol Sin. 2021 Sep 14.. Abstract
submitted by kickingbird at Sep, 15, 2021 from Virol Sin. 2021 Sep 14. (via https://link.springer.com/article/10.1007%2Fs12250-021-00433)
Viruses depend on host cellular metabolism to provide the energy and biosynthetic building blocks required for their replication. In this study, we observed that influenza A virus (H1N1), a single-stranded, ... Li X, Qiao S, Zhao Y, Gu M, Gao R, Liu K, Ge Z, Ma. G1-like PB2 gene improves virus replication and competitive advantage of H9N2 virus. Virus Genes. 2021 Sep 14. Abstract
submitted by kickingbird at Sep, 15, 2021 from Virus Genes. 2021 Sep 14 (via https://link.springer.com/article/10.1007%2Fs11262-021-01870)
H9N2 subtype avian influenza virus has dramatically evolved and undergone extensive reassortment since its emergence in early 1990s in China. The genotype S (G57), emerging in 2007 with the substitution ... Borkenhagen LK, Allen MW, Runstadler JA. Influenza Virus Genotype to Phenotype Predictions Through Machine Learning: A Systematic Review. Emerg Microbes Infect. 2021 Sep 9:1-58.. Abstract
submitted by kickingbird at Sep, 14, 2021 from Emerg Microbes Infect. 2021 Sep 9:1-58. (via https://www.tandfonline.com/doi/full/10.1080/22221751.2021.1)
Background: There is great interest in understanding the viral genomic predictors of phenotypic traits that allow influenza A viruses to adapt to or become more virulent in different hosts. Machine learning ... Rüdiger D, Pelz L, Hein MD, Kupke SY, Reichl U.. Multiscale model of defective interfering particle replication for influenza A virus infection in animal cell culture. PLoS Comput Biol. 2021 Sep 7;17(9):e1009357. Abstract
submitted by kickingbird at Sep, 8, 2021 from PLoS Comput Biol. 2021 Sep 7;17(9):e1009357 (via https://journals.plos.org/ploscompbiol/article?id=10.1371/jo)
Cell culture-derived defective interfering particles (DIPs) are considered for antiviral therapy due to their ability to inhibit influenza A virus (IAV) production. DIPs contain a large internal deletion ... Zhang Z, Guo F, Roy A, Yang J, Luo W, Shen X, Irwi. Evolutionary perspectives and adaptation dynamics of human seasonal influenza viruses from 2009 to 2019: An insight from codon usage. Infect Genet Evol. 2021 Sep 3:105067. Abstract
submitted by kickingbird at Sep, 7, 2021 from Infect Genet Evol. 2021 Sep 3:105067 (via https://www.sciencedirect.com/science/article/abs/pii/S15671)
The annually recurrent seasonal influenza viruses, namely, influenza A viruses (H1N1/pdm2009 and H3N2) and influenza B viruses, contribute substantially to human disease burden. Elucidation of host adaptation, ... Nacken W, Schreiber A, Masemann D, Ludwig S. The Effector Domain of the Influenza A Virus Nonstructural Protein NS1 Triggers Host Shutoff by Mediating Inhibition and Global Deregulation of Host Transcription When Associated with Specific Structu. mBio. 2021 Sep 7:e0219621. Abstract
submitted by kickingbird at Sep, 7, 2021 from mBio. 2021 Sep 7:e0219621 (via https://journals.asm.org/doi/10.1128/mBio.02196-21)
Host shutoff in influenza A virus (IAV) infection is a key process contributing to viral takeover of the cellular machinery and resulting in the downregulation of host gene expression. Analysis of nascently ... Allen JD, Ross TM. Evaluation of Next-Generation H3 Influenza Vaccines in Ferrets Pre-Immune to Historical H3N2 Viruses. Front Immunol. 2021 Aug 12;12:707339. Abstract
submitted by kickingbird at Sep, 7, 2021 from Front Immunol. 2021 Aug 12;12:707339 (via https://www.frontiersin.org/articles/10.3389/fimmu.2021.7073)
Each person has a unique immune history to past influenza virus infections. Exposure to influenza viruses early in life establishes memory B cell populations that influence future immune responses to influenza ... Freyn AW, Pine M, Rosado VC, Benz M, Muramatsu H,. Antigen modifications improve nucleoside-modified mRNA-based influenza virus vaccines in mice. Mol Ther Methods Clin Dev. 2021 Jun 12;22:84-95. Abstract
submitted by kickingbird at Sep, 7, 2021 from Mol Ther Methods Clin Dev. 2021 Jun 12;22:84-95 (via https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8390451/)
Nucleoside-modified, lipid nanoparticle-encapsulated mRNAs have recently emerged as suitable vaccines for influenza viruses and other pathogens in part because the platform allows delivery of multiple ... Ganti K, Han J, Manicassamy B, Lowen AC. Rab11a mediates cell-cell spread and reassortment of influenza A virus genomes via tunneling nanotubes. PLoS Pathog. 2021 Sep 2;17(9):e1009321. Abstract
submitted by kickingbird at Sep, 3, 2021 from PLoS Pathog. 2021 Sep 2;17(9):e1009321 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Influenza A virus [IAV] genomes comprise eight negative strand RNAs packaged into virions in the form of viral ribonucleoproteins [vRNPs]. Rab11a plays a crucial role in the transport of vRNPs from the ... 5328 items, 20/Page, Page[58/267][|<<] [|<] [51] [52] [53] [54] [55] [56] [57] [58] [59] [60] [>|] [>>|] |
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