Yu J, Shang C, Deng X, Jia J, Shang X, Wang Z, Zhe. Time-resolved scRNA-seq reveals transcription dynamics of polarized macrophages with influenza A virus infection and antigen presentation to T cells. Emerg Microbes Infect. 2024 Aug 12:2387450. Abstract
submitted by kickingbird at Aug, 15, 2024 from Emerg Microbes Infect. 2024 Aug 12:2387450 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2024.2)
Throughout history, the influenza A virus has caused numerous devastating global pandemics. Macrophages, as pivotal innate immune cells, exhibit a wide range of immune functions characterized by distinct ... Chi X, Huang G, Wang L, Zhang X, Liu J, Yin Z, Guo. A small protein encoded by PCBP1-AS1 is identified as a key regulator of influenza virus replication via enhancing autophagy. PLoS Pathog. 2024 Aug 13;20(8):e1012461. Abstract
submitted by kickingbird at Aug, 15, 2024 from PLoS Pathog. 2024 Aug 13;20(8):e1012461 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Many annotated long noncoding RNAs (lncRNAs) contain small open reading frames (sORFs), some of which have been demonstrated to encode small proteins or micropeptides with fundamental biological importance. ... Zhang Y, Li L, Xin X, Chang L, Luo H, Qiao W, Xia. Effects of H9N2 avian influenza virus infection on metabolite content and gene expression in chick DF1 cells. Poult Sci. 2024 Jul 30;103(10):104125. Abstract
submitted by kickingbird at Aug, 15, 2024 from Poult Sci. 2024 Jul 30;103(10):104125 (via https://www.sciencedirect.com/science/article/pii/S003257912)
After viral infection, the virus relies on the host cell's complex metabolic and biosynthetic machinery for replication. However, the impact of avian influenza virus (AIV) on metabolites and gene expression ... Li X, Jia T, Wang K, Wang L, Zhou L, Li M, Zhu W,. The PB2 I714S mutation influenced mammalian adaptation of the H3N2 canine influenza virus by interfering with nuclear import efficiency and RNP complex assembly. Emerg Microbes Infect. 2024 Dec;13(1):2387439. Abstract
submitted by kickingbird at Aug, 15, 2024 from Emerg Microbes Infect. 2024 Dec;13(1):2387439 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2024.2)
Avian influenza viruses (AIVs) are the origin of multiple mammal influenza viruses. The genetic determinants of AIVs adapted to humans have been widely elucidated, however, the molecular mechanism of cross-species ... Forna A, Weedop KB, Damodaran L, Hassell N, Kondor. Sequence-based detection of emerging antigenically novel influenza A viruses. Proc Biol Sci. 2024 Aug;291(2028):20240790. Abstract
submitted by kickingbird at Aug, 15, 2024 from Proc Biol Sci. 2024 Aug;291(2028):20240790 (via https://royalsocietypublishing.org/doi/10.1098/rspb.2024.079)
The detection of evolutionary transitions in influenza A (H3N2) viruses' antigenicity is a major obstacle to effective vaccine design and development. In this study, we describe Novel Influenza Virus A ... Ge X, Chen Y, Wu W, Lu J, Wang Y, Li Z. Safety and effectiveness of baloxavir marboxil and oseltamivir for influenza in children: a real-world retrospective study in China. Front Pediatr. 2024 Jul 29;12:1418321. Abstract
submitted by kickingbird at Aug, 14, 2024 from Front Pediatr. 2024 Jul 29;12:1418321 (via https://www.frontiersin.org/journals/pediatrics/articles/10.)
Objectives: To evaluate the safety and effectiveness of baloxavir marboxil (baloxavir) and oseltamivir in pediatric influenza patients in China.Methods: Patients filling a prescription for baloxavir or ... Zeller, M.A., Carnevale de Almeida Moraes, D., Cia. Reverse zoonosis of the 2022–2023 human seasonal H3N2 detected in swine. npj Viruses 2, 27 (2024). Abstract
submitted by kickingbird at Aug, 14, 2024 from npj Viruses 2, 27 (2024) (via https://www.nature.com/articles/s44298-024-00042-4)
The Iowa State University Veterinary Diagnostic Laboratory detected nineteen human-to-swine reverse zoonoses of the 2022–2023 human seasonal H3N2 between November 2022 and November 2023. Cases from seven ... Sekine, W., Kamiki, H., Ishida, H. et al. Adaptation potential of H3N8 canine influenza virus in human respiratory cells. Sci Rep 14, 18750 (2024). Abstract
submitted by kickingbird at Aug, 14, 2024 from Sci Rep 14, 18750 (2024) (via https://www.nature.com/articles/s41598-024-69509-x)
In 2004, the equine-origin H3N8 canine influenza virus (CIV) first caused an outbreak with lethal cases in racing greyhounds in Florida, USA, and then spread to domestic dogs nationwide. Although transmission ... David L Suarez, etc.,al. [preprint]Testing of retail cheese, butter, ice cream and other dairy products for highly pathogenic avian influenza in the US. https://doi.org/10.1101/2024.08.11.24311811. Abstract
submitted by kickingbird at Aug, 13, 2024 from https://doi.org/10.1101/2024.08.11.24311811 (via https://www.medrxiv.org/content/10.1101/2024.08.11.24311811v)
The recent outbreak of highly pathogenic avian influenza (HPAI) in dairy cows has created public health concerns about the potential of consumers being exposed to live virus from commercial dairy products. ... Lingcai Zhao, etc.,al. Host-specific SRSF7 regulates polymerase activity and replication of influenza A virus. Microbes and Infection. Abstract
submitted by kickingbird at Aug, 12, 2024 from Microbes and Infection (via https://www.sciencedirect.com/science/article/pii/S128645792)
Avian influenza viruses crossing the host barrier to infect humans have caused great panic in human society and seriously threatened public health. Herein, we revealed that knockdown of SRSF7 significantly ... Spackman E. A Review of the Stability of Avian Influenza Virus in Materials from Poultry Farms. Avian Dis. 2023 Sep;67(3):229-236. Abstract
submitted by kickingbird at Aug, 12, 2024 from Avian Dis. 2023 Sep;67(3):229-236 (via https://bioone.org/journals/avian-diseases/volume-67/issue-3)
Avian influenza virus (AIV) is widespread among poultry and wild waterfowl. The severity of the disease is variable and the highly pathogenic form can rapidly kill numerous avian species. Understanding ... Brinkley Raynor Bellotti, etc.,al. [preprint]Challenges and lessons learned from preliminary modeling of with-in herd transmission of highly pathogenic avian influenza H5N1 in dairy cattle. https://doi.org/10.1101/2024.08.06.606397. Abstract
submitted by kickingbird at Aug, 11, 2024 from https://doi.org/10.1101/2024.08.06.606397 (via https://www.biorxiv.org/content/10.1101/2024.08.06.606397v1)
The emergence of highly pathogenic avian influenza A H5N1 in dairy cattle raises many questions related to animal health and changes to the risk of an epidemic in humans. We synthesized information currently ... Nico Joel Halwe, etc.,al. [preprint]Outcome of H5N1 clade 2.3.4.4b virus infection in calves and lactating cows. https://doi.org/10.1101/2024.08.09.607272. Abstract
submitted by kickingbird at Aug, 11, 2024 from https://doi.org/10.1101/2024.08.09.607272 (via https://www.biorxiv.org/content/10.1101/2024.08.09.607272v1)
In March 2024, highly pathogenic avian influenza virus (HPAIV) clade 2.3.4.4b H5N1 infections in dairy cows were first reported from Texas, USA. Rapid dissemination to more than 190 farms in 13 states ... Kei Miyakawa, etc.,al. [preprint]Rapid neutralizing assay for circulating H5N1 influenza virus in dairy cows. https://doi.org/10.1101/2024.07.30.605731. Abstract
submitted by kickingbird at Aug, 11, 2024 from https://doi.org/10.1101/2024.07.30.605731 (via https://www.biorxiv.org/content/10.1101/2024.07.30.605731v1)
A rapid and safe neutralization assay is required for emerging highly pathogenic avian influenza viruses, including the H5N1 subtype, which was recently found in cows. Herein, we report a novel neutralization ... Yuan L, Zhang S, Bi R, Liu X, Han Z, Li M, Liao X,. A broad-spectrum multiepitope vaccine against seasonal influenza A and B viruses in mice. EBioMedicine. 2024 Aug 6;106:105269. Abstract
submitted by kickingbird at Aug, 11, 2024 from EBioMedicine. 2024 Aug 6;106:105269 (via https://www.thelancet.com/journals/ebiom/article/PIIS2352-39)
Background: Influenza viruses pose a persistent threat to global public health, necessitating the development of innovative and broadly effective vaccines.Methods: This study focuses on a multiepitope ... Han Z, Mai Q, Zhao Y, Liu X, Cui M, Li M, Chen Y,. Mosaic neuraminidase-based vaccine induces antigen-specific T cell responses against homologous and heterologous influenza viruses. Antiviral Res. 2024 Aug 6;230:105978. Abstract
submitted by kickingbird at Aug, 11, 2024 from Antiviral Res. 2024 Aug 6;230:105978 (via https://www.sciencedirect.com/science/article/abs/pii/S01663)
Seasonal influenza is an annually severe crisis for global public health, and an ideal influenza vaccine is expected to provide broad protection against constantly drifted strains. Compared to highly flexible ... Huang L, Tang W, He L, Li M, Lin X, Hu A, Huang X,. Engineered probiotic Escherichia coli elicits immediate and long-term protection against influenza A virus in mice. Nat Commun. 2024 Aug 9;15(1):6802. Abstract
submitted by kickingbird at Aug, 11, 2024 from Nat Commun. 2024 Aug 9;15(1):6802 (via https://www.nature.com/articles/s41467-024-51182-3)
Influenza virus infection remains a major global health problem and requires a universal vaccine with broad protection against different subtypes as well as a rapid-response vaccine to provide immediate ... Adinda Kok, etc.,al. [preprint]A vaccine antigen central in influenza A(H5) virus antigenic space confers subtype-wide immunity. https://doi.org/10.1101/2024.08.06.606696. Abstract
submitted by kickingbird at Aug, 8, 2024 from https://doi.org/10.1101/2024.08.06.606696 (via https://www.biorxiv.org/content/10.1101/2024.08.06.606696v1)
Highly pathogenic avian influenza A(H5) viruses globally impact wild and domestic birds, and mammals, including humans, underscoring their pandemic potential. The antigenic evolution of the A(H5) hemagglutinin ... Zhang J, Wu Y, Wang Y, Liu P, Liu K, Sun J, Zhang. Influenza A virus infection activates STAT3 to enhance SREBP2 expression, cholesterol biosynthesis, and virus replication. iScience. 2024 Jun 29;27(8):110424. Abstract
submitted by kickingbird at Aug, 8, 2024 from iScience. 2024 Jun 29;27(8):110424 (via https://www.cell.com/iscience/fulltext/S2589-0042(24)01649-3)
Cellular cholesterol plays an important role in influenza A virus (IAV) endocytosis and replication. However, how IAV infection regulates cholesterol biosynthesis remains poorly understood. Here, we report ... Bi Y, Yang J, Wang L, Ran L, Gao GF. Ecology and evolution of avian influenza viruses. Curr Biol. 2024 Aug 5;34(15):R716-R721. Abstract
submitted by kickingbird at Aug, 8, 2024 from Curr Biol. 2024 Aug 5;34(15):R716-R721 (via https://www.cell.com/current-biology/fulltext/S0960-9822(24))
Four types of influenza virus have been identified in nature: influenza A, B, and C viruses are capable of infecting humans, and influenzas A and B cause annual epidemics (seasonal flu) in humans; however, ... 6502 items, 20/Page, Page[57/326][|<<] [|<] [51] [52] [53] [54] [55] [56] [57] [58] [59] [60] [>|] [>>|] |
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