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2021-1-25 15:05:10

Liu LQ, Li Z, Jiao M, Lu J, Zhou JF, Li XY, Liu J,. Development and Assessment of Two Highly Pathogenic Avian Influenza (HPAI) H5N6 Candidate Vaccine Viruses for Pandemic Preparedness. Biomed Environ Sci. 2020 Sep 20;33(9):670-679.  Abstract  
submitted by kickingbird at Oct, 28, 2020 from Biomed Environ Sci. 2020 Sep 20;33(9):670-679 (via http://www.besjournal.com/en/article/doi/10.3967/bes2020.088)
Objective: In China, 24 cases of human infection with highly pathogenic avian influenza (HPAI) H5N6 virus have been confirmed since the first confirmed case in 2014. Therefore, we developed and assessed ...

Quandelacy TM, Cummings DAT, Jiang CQ, Yang B, Kwo. Using serological measures to estimate influenza incidence in the presence of secular trends in exposure and immuno-modulation of antibody response. Influenza Other Respir Viruses. 2020 Oct 27.  Abstract  
submitted by kickingbird at Oct, 28, 2020 from Influenza Other Respir Viruses. 2020 Oct 27 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.12807)
Background: Influenza infection is often measured by a fourfold antibody titer increase over an influenza season (ie seroconversion). However, this approach may fail when influenza seasons are less distinct ...

Wang Y, Chen X, Yuan Y. Antibody Response of a H9 Subtype Avian Influenza Poultry Vaccine on Three Kinds of Wild Birds in Shanghai Zoo. Avian Dis. 2020 Oct 27.  Abstract  
submitted by kickingbird at Oct, 28, 2020 from Avian Dis. 2020 Oct 27 (via https://pubmed.ncbi.nlm.nih.gov/33108447/)
A semi-annual immunization with a commercial inactivated H9 subtype avian influenza virus (AIV) vaccine developed for poultry has been used to prevent and control the avian influenza (AI) infections among ...

Malosh RE, Petrie JG, Callear AP, Monto AS, Martin. Home collection of nasal swabs for detection of influenza in the Household Influenza Vaccine Evaluation Study. Influenza Other Respir Viruses. 2020 Oct 26.  Abstract  
submitted by kickingbird at Oct, 28, 2020 from Influenza Other Respir Viruses. 2020 Oct 26 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.12822)
Background: Community-based studies of influenza and other respiratory viruses (eg, SARS-CoV-2) require laboratory confirmation of infection. During the current COVID-19 pandemic, social distancing guidelines ...

Gao Q, Yang C, Ren C, Zhang S, Gao X, Jin M, Chen. Eukaryotic translation elongation factor 1 delta inhibits the nuclear import of nucleoprotein and PA-PB1 heterodimer of influenza A virus. J Virol. 2020 Oct 21:JVI.01391-20.  Abstract  
submitted by kickingbird at Oct, 26, 2020 from J Virol. 2020 Oct 21:JVI.01391-20 (via https://jvi.asm.org/content/early/2020/10/16/JVI.01391-20)
The viral ribonucleoprotein (vRNP) of the influenza A virus (IAV) is responsible for the viral RNA transcription and replication in the nucleus and its functions rely on host factors. Previous study has ...

Deng L, Xu H, Liu P, Wu S, Shi Y, Lv Y, Chen X. Prolonged exposure to high humidity and high temperature environment can aggravate influenza virus infection through intestinal flora and Nod/RIP2/NF-κB signaling pathway. Vet Microbiol. 2020 Oct 16;251:108896.  Abstract  
submitted by kickingbird at Oct, 26, 2020 from Vet Microbiol. 2020 Oct 16;251:108896 (via https://www.sciencedirect.com/science/article/pii/S037811352)
Seasonal influenza is an acute viral infection caused by influenza virus, which is often prevalent in the summer and winter. The influenza virus can infect pigs and poultry. Some literature reports that ...

Kajiwara N, Nomura N, Ukaji M, Yamamoto N, Kohara. Cell-penetrating peptide-mediated cell entry of H5N1 highly pathogenic avian influenza virus. Sci Rep. 2020 Oct 22;10(1):18008.  Abstract  
submitted by kickingbird at Oct, 26, 2020 from Sci Rep. 2020 Oct 22;10(1):18008 (via https://www.nature.com/articles/s41598-020-74604-w)
H5N1 highly pathogenic avian influenza virus (HPAIV) poses a huge threat to public health and the global economy. These viruses cause systemic infection in poultry and accidental human infection leads ...

Karwelat D, Schmeck B, Ringel M, Benedikter BJ, Hü. Influenza virus-mediated suppression of bronchial Chitinase-3-like 1 secretion promotes secondary pneumococcal infection. FASEB J. 2020 Oct 23.  Abstract  
submitted by kickingbird at Oct, 26, 2020 from FASEB J. 2020 Oct 23 (via https://faseb.onlinelibrary.wiley.com/doi/10.1096/fj.2019029)
Infections of the lung are among the leading causes of death worldwide. Despite the preactivation of innate defense programs during viral infection, secondary bacterial infection substantially elevates ...

Ciminski K, Chase GP, Beer M, Schwemmle M. Influenza A Viruses: Understanding Human Host Determinants. Trends Mol Med. 2020 Oct 20:S1471-4914(20)30261-6.  Abstract  
submitted by kickingbird at Oct, 26, 2020 from Trends Mol Med. 2020 Oct 20:S1471-4914(20)30261-6 (via https://www.cell.com/trends/molecular-medicine/fulltext/S147)
Previous influenza A virus (IAV) pandemics have invariably been caused by the introduction of an emergent IAV strain from an animal host into a human population with no or only little pre-existing immunity ...

Gorsich EE, Webb CT, Merton AA, Hoeting JA, Miller. Continental-scale dynamics of avian influenza in U.S. waterfowl are driven by demography, migration, and temperature. Ecol Appl. 2020 Oct 24:e2245.  Abstract  
submitted by kickingbird at Oct, 26, 2020 from Ecol Appl. 2020 Oct 24:e2245 (via https://esajournals.onlinelibrary.wiley.com/doi/10.1002/eap.)
Emerging diseases of wildlife origin are increasingly spilling over into humans and domestic animals. Surveillance and risk assessments for transmission between these populations are informed by a mechanistic ...

Drori Y, Jacob-Hirsch J, Pando R, Glatman-Freedman. Influenza A Virus Inhibits RSV Infection via a Two-Wave Expression of IFIT Proteins. Viruses. 2020 Oct 16;12(10):E1171.  Abstract  
submitted by kickingbird at Oct, 22, 2020 from Viruses. 2020 Oct 16;12(10):E1171 (via https://www.mdpi.com/1999-4915/12/10/1171)
Influenza viruses and respiratory syncytial virus (RSV) are respiratory viruses that primarily circulate worldwide during the autumn and winter seasons. Seasonal surveillance has shown that RSV infection ...

Li S, Qiao Y, Xu Y, Li P, Nie J, Zhao Q, Chai W, S. Identification of Linear Peptide Immunogens with Verified Broad-spectrum Immunogenicity from the Conserved Regions within the Hemagglutinin Stem Domain of H1N1 Influenza Virus. Immunol Invest. 2020 Oct 20:1-14.  Abstract  
submitted by kickingbird at Oct, 21, 2020 from Immunol Invest. 2020 Oct 20:1-14 (via https://www.tandfonline.com/doi/abs/10.1080/08820139.2020.18)
Background: Influenza A viruses (IAVs) induce acute respiratory disease and cause severe epidemics and pandemics. Since IAVs exhibit antigenic variation and genome reassortment, the development of broad-spectrum ...

Ohta M, Bannai H, Nemoto M, Kambayashi Y, Tamura N. Antibody Responses Against Equine Influenza Virus Induced by Concurrent and by Consecutive Use of an Inactivated Equine Influenza Virus Vaccine and a Modified Live Equine Herpesvirus Type 1 Vaccine in. J Equine Vet Sci. 2020 Nov;94:103221.  Abstract  
submitted by kickingbird at Oct, 21, 2020 from J Equine Vet Sci. 2020 Nov;94:103221 (via https://www.sciencedirect.com/science/article/abs/pii/S07370)
An inactivated equine influenza virus (EIV) vaccine and a live equine herpesvirus type 1 (EHV-1) vaccine are usually administered concurrently to Thoroughbred racehorses in Japan. The objective of this ...

Shu B, Kirby MK, Warnes C, Sessions WM, Davis WG,. Detection and discrimination of influenza B Victoria lineage deletion variant viruses by real-time RT-PCR. Euro Surveill. 2020 Oct;25(41).  Abstract  
submitted by kickingbird at Oct, 20, 2020 from Euro Surveill. 2020 Oct;25(41) (via https://www.eurosurveillance.org/content/10.2807/1560-7917.E)
BackgroundDuring the 2016/17 influenza season, influenza B/VIC lineage variant viruses emerged with two (K162N163) or three (K162N163D164) amino acid (aa) deletions in the haemagglutinin (HA) protein. ...

Martin BE, Harris JD, Sun J, Koelle K, Brooke CB. Cellular co-infection can modulate the efficiency of influenza A virus production and shape the interferon response. PLoS Pathog. 2020 Oct 16;16(10):e1008974.  Abstract  
submitted by kickingbird at Oct, 20, 2020 from PLoS Pathog. 2020 Oct 16;16(10):e1008974 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
During viral infection, the numbers of virions infecting individual cells can vary significantly over time and space. The functional consequences of this variation in cellular multiplicity of infection ...

Horman WSJ, Nguyen THO, Kedzierska K, Butler J, Sh. The Dynamics of the Ferret Immune Response During H7N9 Influenza Virus Infection. Front Immunol. 2020 Sep 24;11:559113.  Abstract  
submitted by kickingbird at Oct, 20, 2020 from Front Immunol. 2020 Sep 24;11:559113 (via https://www.frontiersin.org/articles/10.3389/fimmu.2020.5591)
As the recent outbreak of SARS-CoV-2 has highlighted, the threat of a pandemic event from zoonotic viruses, such as the deadly influenza A/H7N9 virus subtype, continues to be a major global health concern. ...

Yang J, Huang X, Liu Y, Zhao D, Han K, Zhang L, Li. Analysis of the microRNA expression profiles of chicken dendritic cells in response to H9N2 avian influenza virus infection. Vet Res. 2020 Oct 17;51(1):132.  Abstract  
submitted by kickingbird at Oct, 20, 2020 from Vet Res. 2020 Oct 17;51(1):132 (via https://veterinaryresearch.biomedcentral.com/articles/10.118)
MicroRNA (miRNA) plays a key role in virus-host interactions. Here, we employed deep sequencing technology to determine cellular miRNA expression profiles in chicken dendritic cells infected with H9N2 ...

Hu J, Kong M, Cui Z, Gao Z, Ma C, Hu Z, Jiao X, Li. PA-X protein of H5N1 avian influenza virus inhibits NF-kappaB activity, a potential mechanism for PA-X counteracting the host innate immune responses. Vet Microbiol. 2020 Sep 18;250:108838.  Abstract  
submitted by kickingbird at Oct, 14, 2020 from Vet Microbiol. 2020 Sep 18;250:108838 (via https://www.sciencedirect.com/science/article/pii/S037811352)
PA-X is a fusion protein of influenza virus which plays a crucial role in modulating influenza virus-induced host innate immune response and subsequent pathogenicity. However, the potential mechanism of ...

Sitaras I, Spackman E, de Jong MCM, Parris DJ. Selection and Antigenic Characterization of Immune-Escape Mutants of H7N2 Low Pathogenic Avian Influenza Virus Using Homologous Polyclonal Sera. Virus Res. 2020 Oct 9:198188.  Abstract  
submitted by kickingbird at Oct, 14, 2020 from Virus Res. 2020 Oct 9:198188 (via https://www.sciencedirect.com/science/article/pii/S016817022)
Understanding the dynamics of the selection of influenza A immune escape variants by serum antibody is critical for designing effective vaccination programs for animals, especially poultry where large ...

Heindel DW, Koppolu S, Zhang Y, Kasper B, Meche L,. Glycomic analysis of host response reveals high mannose as a key mediator of influenza severity. Proc Natl Acad Sci U S A. 2020 Oct 12:202008203.  Abstract  
submitted by kickingbird at Oct, 14, 2020 from Proc Natl Acad Sci U S A. 2020 Oct 12:202008203 (via https://www.pnas.org/content/early/2020/10/09/2008203117)
Influenza virus infections cause a wide variety of outcomes, from mild disease to 3 to 5 million cases of severe illness and ~290,000 to 645,000 deaths annually worldwide. The molecular mechanisms underlying ...

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