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2025-12-18 2:22:50
Article

Liu S, Sun Y, Peng Y, Xu C, Song S, Yan L. Cellular hnRNP AB inhibits avian influenza virus RNA synthesis via blocking UAP56-mediated nuclear export of PB2 mRNA. Vet Res. 2025 Nov 21;56(1):223.  Abstract  
submitted by kickingbird at Nov, 23, 2025 from Vet Res. 2025 Nov 21;56(1):223 (via https://veterinaryresearch.biomedcentral.com/articles/10.118)
Avian influenza viral ribonucleoproteins (vRNPs) complete genome transcription and replication by interacting with host proteins, and RNA-dependent RNA polymerase (RdRp) is its major component. PB2 is ...

Neusser J, Zierer A, Riedl A, Javanmardi J, Rubio-. High-Resolution Wastewater-Based Surveillance of Three Influenza Seasons (2022-2025) Reveals Distinct Seasonal Patterns of Viral Activity in Munich, Germany. Microorganisms. 2025; 13(11):2630.  Abstract  
submitted by kickingbird at Nov, 21, 2025 from Microorganisms. 2025; 13(11):2630 (via https://www.mdpi.com/2076-2607/13/11/2630)
In the Northern Hemisphere, annual waves of influenza disease with varying degrees of spread and severity are observed each winter. With wastewater-based surveillance (WBS), including both centralized ...

Rashid M-u, Yasmin T, Coombs KM. HSPA5, a Host Cellular Heat-Shock Protein Required for Influenza a Virus Replication. International Journal of Molecular Sciences. 2025;.  Abstract  
submitted by kickingbird at Nov, 21, 2025 from International Journal of Molecular Sciences. 2025; (via https://www.mdpi.com/1422-0067/26/22/10998)
The Influenza A Virus (IAV) is known to hijack cellular proteins during its replication. IAV infection increases the expression of Heat-shock-protein family A (Hsp70) member 5 (HSPA5) in human cells, but ...

Qiuqi Kan, etc.,al. Genetic characteristics of three duck-original H1N1 influenza A viruses isolated in China. Veterinary Microbiology.  Abstract  
submitted by kickingbird at Nov, 21, 2025 from Veterinary Microbiology (via https://www.sciencedirect.com/science/article/abs/pii/S03781)
Waterfowl play a pivotal role in the evolution of the influenza A virus (IAV), which harbor an extensive repertoire of IAV and act as long-term reservoirs in which low-pathogenic strains can reassort and ...

Alharby, T.N., Alanazi, M., Khan, K.U. et al. Identifying antivirals against influenza PA endonuclease with machine learning-based activity prediction, DFT optimization, and molecular dynamics simulation. Mol Divers (2025).  Abstract  
submitted by kickingbird at Nov, 21, 2025 from Mol Divers (2025) (via https://link.springer.com/article/10.1007/s11030-025-11403-3)
Increasing concern about highly pathogenic avian influenza A (H5N1) is prompting the development of new antivirals directed toward conserved viral entities that are resistant to mutational escape. Here, ...

Zhao, Z., Tian, J., Bai, X., Li, M., Song, X., Li,. Epidemiology, evolution, and biological characteristics of avian influenza a (H11) viruses from wild birds. Virulence.  Abstract  
submitted by kickingbird at Nov, 21, 2025 from Virulence (via https://www.tandfonline.com/doi/full/10.1080/21505594.2025.2)
H11 subtype avian influenza viruses (AIVs) have been identified in both wild and domestic birds. H11N9 viruses from wild birds provided the NA gene to human H7N9 virus in 2013 in China, which caused five ...

Nath H, Arndt A, Mann JT, Baker SF. 0. Tandem split-GFP influenza A viruses for sensitive and accurate replication analyses. Microbiol Spectr 0:e02772-25.  Abstract  
submitted by kickingbird at Nov, 20, 2025 from Microbiol Spectr 0:e02772-25 (via https://journals.asm.org/doi/10.1128/spectrum.02772-25)
Reporter influenza A viruses (IAVs) are valuable tools for studying virus fitness, screening antivirals, and assessing host–virus interactions. However, the compact and segmented nature of the IAV genome ...

Oshin Ley Garcia, Tamiru Alkie, Frank van der Me. Serological Evidence of Highly Pathogenic Avian Influenza (H5N1) in Invasive Wild Pigs in Western Canada. Transboundary and Emerging Diseases.  Abstract  
submitted by kickingbird at Nov, 20, 2025 from Transboundary and Emerging Diseases (via https://onlinelibrary.wiley.com/doi/10.1155/tbed/2720469)
Influenza A virus (IAV) can infect a wide range of hosts, including wild and domestic pigs. Swine play an important role in influenza evolution and epidemiology due to their ability to get infected with ...

Fosse JH, R?mo G, Bonfante F, Myhrvold IK, Soetart. Detection of Antibodies Specific to H5 Avian Influenza Virus in a Sheep in Norway, June 2024, 11 Months After an Outbreak of Highly Pathogenic Avian Influenza in a Nearby Seabird Colony. Influenza Other Respir Viruses. 2025 Nov;19(11).  Abstract  
submitted by kickingbird at Nov, 20, 2025 from Influenza Other Respir Viruses. 2025 Nov;19(11) (via https://onlinelibrary.wiley.com/doi/10.1111/irv.70182)
A 2023 outbreak of highly pathogenic avian influenza in seabirds in Norway caused substantial environmental contamination of grazing areas frequented by local sheep. Eleven months later, 220 sheep were ...

Martí-Garcia, B., Lean, F.Z.X., Nú?ez, A. et al. Natural infections of highly pathogenic avian influenza virus H5N1 in wild birds between 2020 and 2023 in the UK: a retrospective study with focus on microscopic lesions, viral distribution and neurot. Vet Res 56, 218 (2025).  Abstract  
submitted by kickingbird at Nov, 19, 2025 from Vet Res 56, 218 (2025) (via https://veterinaryresearch.biomedcentral.com/articles/10.118)
Since the emergence of highly pathogenic avian influenza (HPAI) H5N1 clade 2.3.4.4 Goose/Guangdong lineage in Europe in 2014, an unprecedented outbreak occurred during the 2021–2022 epidemiological year, ...

Cherian, P., Menon, G.I. Modelling a potential zoonotic spillover event of H5N1 influenza. BMC Public Health 25, 3983 (2025).  Abstract  
submitted by kickingbird at Nov, 19, 2025 from BMC Public Health 25, 3983 (2025) (via https://bmcpublichealth.biomedcentral.com/articles/10.1186/s)
BackgroundHighly Pathogenic Avian Influenza (HPAI) is a prominent candidate for a future human pandemic arising from a zoonotic spillover event. Its best-known subtype is H5N1, with South- or South-East ...

Zhao Y, Wang Y, Huang K, Wang F, Wang Y. Influenza a(H1N1) virus infection impairs syncytiotrophoblast functions by promoting ferroptosis through the TNF-α/ISG15/EGR1 axis. Virol J. 2025 Nov 17;22(1):379.  Abstract  
submitted by kickingbird at Nov, 19, 2025 from Virol J. 2025 Nov 17;22(1):379 (via https://virologyj.biomedcentral.com/articles/10.1186/s12985-)
Influenza A virus (IAV) is linked to adverse pregnancy outcomes like spontaneous abortion, preterm birth, and neonatal death. Inhibition of trophoblast cell fusion by IAV infection is a key factor contributing ...

Rahman M, Uyeki TM, Peiris M, Cardwell JM, Nguipdo. A Cross-Sectional Virological and Sero-Epidemiological Study of Exposures to Avian Influenza A(H5N1) and A(H9N2) Viruses in Live Bird Market Workers in Dhaka, Bangladesh. Influenza Other Respir Viruses. 2025 Nov;19(11):e7.  Abstract  
submitted by kickingbird at Nov, 18, 2025 from Influenza Other Respir Viruses. 2025 Nov;19(11):e7 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.70189)
Background: Avian influenza A viruses (AIVs) are endemic among poultry in Bangladesh sold at live bird markets (LBMs). We assessed virologic and serologic evidence of exposure to AIVs among LBM workers.Methods: ...

Zhu H, He D, Liu S, Fan X, Gao L, Guo L, Zhang Z.. H6N6 Avian Influenza Virus Infection Induced Pyroptosis of M1 Macrophages by Activating Caspase-1. Viruses. 2025; 17(11):1492.  Abstract  
submitted by kickingbird at Nov, 17, 2025 from Viruses. 2025; 17(11):1492 (via https://www.mdpi.com/1999-4915/17/11/1492)
The H6N6 avian influenza virus has expanded its host range from birds to mammals. Some strains can now bind to human-like receptors, raising concerns about human infection. Although H6N6 is a low-pathogenic ...

Facchini M, De Marco MA, Piacentini S, Di Martino. Divergent Avian Influenza H10 Viruses from Sympatric Waterbird Species in Italy: Zoonotic Potential Assessment by Molecular Markers. Microorganisms. 2025; 13(11):2575.  Abstract  
submitted by kickingbird at Nov, 17, 2025 from Microorganisms. 2025; 13(11):2575 (via https://www.mdpi.com/2076-2607/13/11/2575)
Avian influenza viruses (AIVs) of H10 subtype are able to circulate in domestic and wild bird populations but can also spill over and adapt to mammals, posing a continuous risk to biodiversity conservation, ...

Zhang M, Luo S, Xie Z, Li M, Xie L, Fan Q, Wang C,. Genetic Evolution of H9N2 Avian Influenza Virus in Guangxi, China. Microorganisms. 2025; 13(11):2579.  Abstract  
submitted by kickingbird at Nov, 17, 2025 from Microorganisms. 2025; 13(11):2579 (via https://www.mdpi.com/2076-2607/13/11/2579)
H9N2 avian influenza virus (AIV) is widely prevalent in poultry in China. To understand the genetic characteristics and evolution of H9N2 AIVs in Guangxi, southern China, the complete genomes of H9N2 AIVs ...

Zheng H, Chen Y, Gao R, Yang W, Lu X, Chen Y, Gu M. NA-N322S and G389D mutations synergize with PB2-627K to enhance H7N9 pathogenicity in mammals. Vet Microbiol. 2025 Oct 30;312:11077.  Abstract  
submitted by kickingbird at Nov, 16, 2025 from Vet Microbiol. 2025 Oct 30;312:11077 (via https://www.sciencedirect.com/science/article/abs/pii/S03781)
The H7N9 subtype avian influenza virus (AIV) is currently the subtype with the highest number of human infection cases, with a mortality rate of nearly 40 %,40 %, posing a serious threat to public health. ...

Sullivan J, Poulson R, Olsen GH, Berlin AM, Cao Z,. Rapid increase in antibodies to influenza A virus H5 and N1 in lesser scaup (Aythya Affinis) following the introduction of 2.3.4.4b H5N1 into north America. Can J Microbiol. 2025 Nov 13.  Abstract  
submitted by kickingbird at Nov, 16, 2025 from Can J Microbiol. 2025 Nov 13 (via https://cdnsciencepub.com/doi/10.1139/cjm-2025-0176)
Clade 2.3.4.4b Eurasian-origin H5N1 entered North America in late 2021 and spread across the continent. While studies have characterized the antibody response mounted by dabbling ducks following exposure, ...

Hunter Joseph Ries, etc.,al. [preprint]Weak selection and stochastic processes limit the emergence of antigenic variants during household transmission of influenza A viruses. https://doi.org/10.1101/2025.11.04.686470.  Abstract  
submitted by kickingbird at Nov, 15, 2025 from https://doi.org/10.1101/2025.11.04.686470 (via https://www.biorxiv.org/content/10.1101/2025.11.04.686470v2)
Influenza viruses undergo antigenic drift, the gradual accumulation of mutations that cause antigenic changes in the viral surface proteins hemagglutinin (HA) and neuraminidase (NA). Although selection ...

Chu X, Yin X, Tian Y, Jiang W, Zhao Z, Wang J, Cao. Characterizations of a novel triple-reassortant H3N3 avian influenza A virus isolated from chickens in China. Poult Sci. 2025 Nov 2;104(12):106048.  Abstract  
submitted by kickingbird at Nov, 15, 2025 from Poult Sci. 2025 Nov 2;104(12):106048 (via https://www.sciencedirect.com/science/article/pii/S003257912)
The emergence of novel H3N8 and H10N3 avian influenza A viruses (IAVs) circulating in chicken flocks in China has raised significant concerns to their spillovers in humans and associated economic losses. ...

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