Zhang X, et al. Pathogenesis of co-infections of influenza D virus and Mannheimia haemolytica in cattle. Vet Microbiol. 2019 Apr;231:246-253.. Abstract
submitted by kickingbird at Apr, 9, 2019 from Vet Microbiol. 2019 Apr;231:246-253. (via https://www.sciencedirect.com/science/article/pii/S037811351)
Bovine respiratory disease (BRD) is economically significant, and influenza D virus (IDV) is commonly identified in cattle with BRD. Mannheimia haemolytica (MHA) is an opportunistic bacterial contributor ...
Mamerow S, et al. Double-attenuated influenza virus elicits broad protection against challenge viruses with different serotypes in swine. Vet Microbiol. 2019 Apr;231:160-168.. Abstract
submitted by kickingbird at Apr, 9, 2019 from Vet Microbiol. 2019 Apr;231:160-168. (via https://www.sciencedirect.com/science/article/pii/S037811351)
Influenza A viruses (IAV) have caused seasonal epidemics and severe pandemics in humans. Novel pandemic strains as in 2009 may emerge from pigs, serving as perpetual virus reservoir. However, reliably ...
Marr LC, Tang JW, Van Mullekom J, Lakdawala SS. Mechanistic insights into the effect of humidity on airborne influenza virus survival, transmission and incidence. J R Soc Interface. 2019 Jan 31;16(150):20180298. Abstract
submitted by kickingbird at Apr, 9, 2019 from J R Soc Interface. 2019 Jan 31;16(150):20180298 (via https://royalsocietypublishing.org/doi/10.1098/rsif.2018.029)
Influenza incidence and seasonality, along with virus survival and transmission, appear to depend at least partly on humidity, and recent studies have suggested that absolute humidity (AH) is more important ...
Andronico A, et al. Highly pathogenic avian influenza H5N8 in south-west France 2016-2017: A modeling study of control strategies. Epidemics. 2019 Mar 28. Abstract
submitted by kickingbird at Apr, 7, 2019 from Epidemics. 2019 Mar 28 (via https://www.sciencedirect.com/science/article/pii/S175543651)
In the winter 2016-2017 the largest epidemic of highly pathogenic avian influenza (HPAI) ever recorded in the European Union spread to all 28 member states. France was hit particularly hard and reported ...
Bo?i? B, et al. Comparative pathological findings in mute swans (Cygnus olor) naturally infected with highly pathogenic Avian influenza viruses H5N1 and H5N8 in Serbia. Vet Ital. 2019 Mar 31;55(1):95-101. Abstract
submitted by kickingbird at Apr, 7, 2019 from Vet Ital. 2019 Mar 31;55(1):95-101 (via http://www.izs.it/vet_italiana/2019/55_1/VetIt_1463_7919_2.p)
The aim of this study was to compare pathological lesions and viral antigen expression in the organs of mute swans (Cygnus olor) naturally infected with highly pathogenic avian influenza virus subtypes ...
Sun W, et al. Development of Influenza B Universal Vaccine Candidates using the “Mosaic” Hemagglutinin Approach. J Virol. 2019 Apr 3.. Abstract
submitted by kickingbird at Apr, 6, 2019 from J Virol. 2019 Apr 3. (via https://jvi.asm.org/content/early/2019/03/28/JVI.00333-19)
Influenza B viruses cause seasonal epidemics and are a considerable burden to public health. However, protection by current seasonal vaccines is suboptimal due to the antigenic changes of the circulating ...
Akole A, Warner JM. Model of influenza virus acidification. PLoS ONE 14(4): e0214448.. Abstract
submitted by kickingbird at Apr, 6, 2019 from PLoS ONE 14(4): e0214448. (via https://journals.plos.org/plosone/article?id=10.1371/journal)
Internal acidification of the influenza virus, mediated by the M2 proton channel, is a key step in its life cycle. The interior M1 protein shell dissolves at pH~5.5 to 6.0, allowing the release of vRNA ...
Ciminski K, et al. Human MxA is a potent interspecies barrier for the novel bat-derived influenza A-like virus H18N11. Emerg Microbes Infect. 2019;8(1):556-563.. Abstract
submitted by kickingbird at Apr, 5, 2019 from Emerg Microbes Infect. 2019;8(1):556-563. (via https://www.tandfonline.com/doi/full/10.1080/22221751.2019.1)
The human innate immune factor MxA represents an effective interspecies barrier for zoonotic influenza A viruses (IAVs) of animal origin. Accordingly, human but not avian IAVs efficiently escape the antiviral ...
Altman MO, et al. Human Influenza A Virus Hemagglutinin Glycan Evolution Follows a Temporal Pattern to a Glycan Limit. MBio. 2019 Apr 2;10(2).. Abstract
submitted by kickingbird at Apr, 5, 2019 from MBio. 2019 Apr 2;10(2). (via https://mbio.asm.org/content/10/2/e00204-19)
Human antibody-based immunity to influenza A virus is limited by antigenic drift resulting from amino acid substitutions in the hemagglutinin (HA) head domain. Glycan addition can cause large antigenic ...
Li Y, et al. Genotypic evolution and epidemiological characteristics of H9N2 influenza virus in Shandong Province, China. Poult Sci. 2019 Apr 2. Abstract
submitted by kickingbird at Apr, 5, 2019 from Poult Sci. 2019 Apr 2 (via https://academic.oup.com/ps/advance-article-abstract/doi/10.)
H9N2 avian influenza has been prevalent in chicken flocks of China for years. In the first half year of 2018, clinical cases of suspected H9N2 infection were collected from chicken flocks in Shandong province. ...
Qiu Y, et al. Characterization of three clade 126.96.36.199 H5 highly pathogenic avian influenza viruses isolated from wild birds. J Infect. 2019 Mar 27. pii: S0163-4453(19)30096-9.. Abstract
submitted by kickingbird at Apr, 1, 2019 from J Infect. 2019 Mar 27. pii: S0163-4453(19)30096-9. (via https://www.journalofinfection.com/article/S0163-4453(19)300)
We isolated and characterized three H5 HPAIVs with different NA subtypes (N1, N6 and N8) during avian influenza virus (AIV) surveillance in wild birds during 2015-2016. The P126/H5N1, P560/H5N6 and ST/H5N8 ...
Hsieh MS, Chang YC, He JL, Juang RH. Positive charge of Arg-201 on hemagglutinin is required for the binding of H6N1 avian influenza virus to its target through a two-step process. Virus Res. 2019 Mar 26. Abstract
submitted by kickingbird at Mar, 31, 2019 from Virus Res. 2019 Mar 26 (via https://www.sciencedirect.com/science/article/abs/pii/S01681)
In our previous study, we produced a monoclonal antibody EB2 that recognized an epitope in the HA1 domain on the hemagglutinin (HA) of H6N1 influenza virus (A/chicken/Taiwan/2838?V/00). The residue Arg-201 ...
Kyt?maa S, et al. Association of Influenza-like Illness Activity With Hospitalizations for Heart Failure: The Atherosclerosis Risk in Communities Study. JAMA Cardiol. 2019 Mar 27. Abstract
submitted by kickingbird at Mar, 30, 2019 from JAMA Cardiol. 2019 Mar 27 (via https://jamanetwork.com/journals/jamacardiology/fullarticle/)
Importance: Influenza is associated with an increased risk of cardiovascular events, but to our knowledge, few studies have explored the temporal association between influenza activity and hospitalizations, ...
Villalón-Letelier F, Reading PC. Unraveling the role of the MOV10 RNA helicase during influenza A virus infection. Biochem J. 2019 Mar 27;476(6):1005-1008.. Abstract
submitted by kickingbird at Mar, 30, 2019 from Biochem J. 2019 Mar 27;476(6):1005-1008. (via http://www.biochemj.org/content/476/6/1005)
Moloney leukemia virus 10 (MOV10) is an interferon-inducible RNA helicase that has been implicated in a broad range of cellular functions, including modulating the replication of a diverse range of viruses. ...
Drews K, et al. Glucosylceramidase Maintains Influenza Infection By Regulating Endocytosis. J Virol. 2019 Mar 27. Abstract
submitted by kickingbird at Mar, 30, 2019 from J Virol. 2019 Mar 27 (via https://jvi.asm.org/content/early/2019/03/25/JVI.00017-19)
Influenza is an RNA virus encapsulated in a lipid bilayer derived from the host cell plasma membrane. Previous studies showed that influenza infection depends on cellular lipids including the sphingolipids ...
Gutman SN, et al. Serologic investigation of exposure to influenza A virus H3N2 infection in dogs and cats in the United States. J Vet Diagn Invest. 2019 Mar;31(2):250-254. Abstract
submitted by kickingbird at Mar, 29, 2019 from J Vet Diagn Invest. 2019 Mar;31(2):250-254 (via https://journals.sagepub.com/doi/abs/10.1177/104063871882435)
We investigated, in a cross-sectional study, the prevalence of antibodies against canine influenza A virus (CIV) H3N2 in serum samples collected from dogs and cats using a commercial ELISA and a hemagglutination ...
Takashita E, et al. Influenza A(H3N2) virus exhibiting reduced susceptibility to baloxavir due to a polymerase acidic subunit I38T substitution detected from a hospitalised child without prior baloxavir treatment, Japan,. Euro Surveill. 2019 Mar;24(12).. Abstract
submitted by kickingbird at Mar, 29, 2019 from Euro Surveill. 2019 Mar;24(12). (via https://www.eurosurveillance.org/content/10.2807/1560-7917.E)
In January 2019, two influenza A(H3N2) viruses carrying an I38T substitution in the polymerase acidic subunit (PA), which confers reduced susceptibility to baloxavir, were detected from epidemiologically ...
Everett HE, et al. Vaccine-mediated protection of pigs against infection with pandemic H1N1 2009 swine influenza A virus requires a close antigenic match between the vaccine antigen and challenge virus. Vaccine. 2019 Mar 23.. Abstract
submitted by kickingbird at Mar, 29, 2019 from Vaccine. 2019 Mar 23. (via https://www.sciencedirect.com/science/article/pii/S0264410X1)
Swine influenza A virus (SwIV) infection has considerable economic and animal welfare consequences and, because of the zoonotic potential, can also have public health implications. The 2009 pandemic H1N1 ...
Shafiuddin M, Boon ACM. RNA Sequence Features Are at the Core of Influenza a Virus Genome Packaging. J Mol Biol. 2019 Mar 23.. Abstract
submitted by kickingbird at Mar, 29, 2019 from J Mol Biol. 2019 Mar 23. (via https://www.sciencedirect.com/science/article/pii/S002228361)
The influenza A virus (IAV), a respiratory pathogen for humans, poses serious medical and economic challenges to global healthcare systems. The IAV genome, consisting of eight single-stranded viral RNA ...
Sun H, et al. H9N2 Viruses Isolated From Mammals Replicated in Mice at Higher Levels Than Avian-Origin Viruses. Front Microbiol. 2019 Mar 11. Abstract
submitted by kickingbird at Mar, 29, 2019 from Front Microbiol. 2019 Mar 11 (via https://www.frontiersin.org/articles/10.3389/fmicb.2019.0041)
H9N2 subtype influenza A virus (IAV) has more than 20 genotypes that are able to cross species barriers and expand from birds to mammals and humans. To better understand the impact of different H9N2 genotypes ...
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