Ayrton S Gouveia, Leonardo G Mata, Daniel A.M. Vil. [preprint]High cumulative viral titers of influenza virus in animals with significant disease fatality rates indicate a potential trade-off between fatality and transmissibility. https://doi.org/10.1101/2024.12.11.627227. Abstract
submitted by kickingbird at Dec, 16, 2024 from https://doi.org/10.1101/2024.12.11.627227 (via https://www.biorxiv.org/content/10.1101/2024.12.11.627227v1)
Evaluating the trade-off hypothesis for the evolution of virulence using empirical data poses significant challenges. The hypothesis suggests that pathogens evolve to maximize transmissibility, but fatality ... Alessandro Zulli, etc.,al. Infectivity and Persistence of Influenza A Virus in Raw Milk. Environ. Sci. Technol. Lett. 2024. Abstract
submitted by kickingbird at Dec, 15, 2024 from Environ. Sci. Technol. Lett. 2024 (via https://pubs.acs.org/doi/10.1021/acs.estlett.4c00971)
Influenza A viruses present important public health risks, with recent outbreaks of highly pathogenic avian influenza (HPAI) H5N1 in dairy cattle raising concerns about potential transmission through raw ... Goraichuk IV, Risalvato J, Pantin-Jackwood M, Suar. Improved influenza A whole-genome sequencing protocol. Front Cell Infect Microbiol. 2024 Nov 28;14:149727. Abstract
submitted by kickingbird at Dec, 15, 2024 from Front Cell Infect Microbiol. 2024 Nov 28;14:149727 (via https://www.frontiersin.org/journals/cellular-and-infection-)
Influenza A virus poses significant public health challenges due to its high mutation rate and zoonotic potential. Whole-genome sequencing (WGS) is crucial for monitoring and characterizing these viruses. ... Ssematimba A, Malladi S, Bonney PJ, St Charles KM,. Estimating the time of Highly Pathogenic Avian Influenza virus introduction into United States poultry flocks during the 2022/24 epizootic. PLoS One. 2024 Dec 13;19(12):e0310733. Abstract
submitted by kickingbird at Dec, 15, 2024 from PLoS One. 2024 Dec 13;19(12):e0310733 (via https://journals.plos.org/plosone/article?id=10.1371/journal)
Following confirmation of the first case of the ongoing U.S. HPAI H5N1 epizootic in commercial poultry on February 8, 2022, the virus has continued to devastate the U.S. poultry sector and the pathogen ... Mainenti M, Siepker C, Magstadt DR, Gauger P, Baum. Distribution of lesions and detection of influenza A(H5N1) virus, clade 2.3.4.4b, in ante- and postmortem samples from naturally infected domestic cats on U.S. dairy farms. J Vet Diagn Invest. 2024 Dec 14:10406387241300464. Abstract
submitted by kickingbird at Dec, 15, 2024 from J Vet Diagn Invest. 2024 Dec 14:10406387241300464 (via https://journals.sagepub.com/doi/10.1177/10406387241300464)
In March 2024, highly pathogenic avian influenza A(H5N1) virus, clade 2.3.4.4b, was detected in dairy cows in the United States, and at the same time in resident cats on affected farms. To help guide sample ... Williams SL, Qi L, Sheng ZM, Xiao Y, Freeman A, Ma. Effect of pandemic influenza A virus PB1 genes of avian origin on viral RNA polymerase activity and pathogenicity. Sci Adv. 2024 Dec 13;10(50):eads5735. Abstract
submitted by kickingbird at Dec, 15, 2024 from Sci Adv. 2024 Dec 13;10(50):eads5735 (via https://www.science.org/doi/10.1126/sciadv.ads5735)
Zoonotic influenza A virus (IAV) infections pose a substantial threat to global health. The influenza RNA-dependent RNA polymerase (RdRp) comprises the PB2, PB1, and PA proteins. Of the last four pandemic ... Sreenivasan CC, Thomas M, Kaushik RS, Wang D, Li F. Influenza A in Bovine Species: A Narrative Literature Review. Viruses. 2019 Jun 17;11(6):561. Abstract
submitted by kickingbird at Dec, 14, 2024 from Viruses. 2019 Jun 17;11(6):561 (via https://www.mdpi.com/1999-4915/11/6/561)
It is quite intriguing that bovines were largely unaffected by influenza A, even though most of the domesticated and wild animals/birds at the human-animal interface succumbed to infection over the past ... Kieran TJ, Sun X, Maines TR, Belser JA. Optimal thresholds and key parameters for predicting influenza A virus transmission events in ferrets. Npj Viruses. 2024;2(1):64. Abstract
submitted by kickingbird at Dec, 13, 2024 from Npj Viruses. 2024;2(1):64 (via https://www.nature.com/articles/s44298-024-00074-w)
Although assessments of influenza A virus transmissibility in the ferret model play a critical role in pandemic risk evaluations, few studies have investigated which virological data collected from virus-inoculated ... Borkenhagen LK, Runstadler JA. Examining the Influenza A Virus Sialic Acid Binding Preference Predictions of a Sequence-Based Convolutional Neural Network. Influenza Other Respir Viruses. 2024 Dec;18(12):e7. Abstract
submitted by kickingbird at Dec, 13, 2024 from Influenza Other Respir Viruses. 2024 Dec;18(12):e7 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.70044)
Background: Though receptor binding specificity is well established as a contributor to host tropism and spillover potential of influenza A viruses, determining receptor binding preference of a specific ... Joao Paulo Portela Catani, etc.,al. [preprint]The antigenic landscape of N1 neuraminidase in human influenza A virus strains isolated between 2009 and 2020. https://doi.org/10.1101/2024.12.10.627724. Abstract
submitted by kickingbird at Dec, 12, 2024 from https://doi.org/10.1101/2024.12.10.627724 (via https://www.biorxiv.org/content/10.1101/2024.12.10.627724v1)
The clinical burden caused by influenza can be mitigated by the prophylactic use of seasonal influenza vaccines. Their immunogen composition is revised biannually to optimally match the antigenic drift ... Elyse Stachler, etc.,al. [preprint]Establishing methods to monitor H5N1 influenza virus in dairy cattle milk. https://doi.org/10.1101/2024.12.04.24318491. Abstract
submitted by kickingbird at Dec, 11, 2024 from https://doi.org/10.1101/2024.12.04.24318491 (via https://www.medrxiv.org/content/10.1101/2024.12.04.24318491v)
Highly Pathogenic Avian Influenza strain H5N1 has caused a multi-state outbreak among US dairy cattle, spreading across 15 states and infecting hundreds of herds since its onset. We rapidly developed and ... Hubbard LE, Stelzer EA, Poulson RL, Kolpin DW, Sza. Development of a Large-Volume Concentration Method to Recover Infectious Avian Influenza Virus from the Aquatic Environment. Viruses. 2024; 16(12):1898. Abstract
submitted by kickingbird at Dec, 11, 2024 from Viruses. 2024; 16(12):1898 (via https://www.mdpi.com/1999-4915/16/12/1898)
Since late 2021, outbreaks of highly pathogenic avian influenza virus have caused a record number of mortalities in wild birds, domestic poultry, and mammals in North America. Wetlands are plausible environmental ... Ramos-Martínez I, Ramos-Martínez E, Saavedra-Monta. Meta-Analysis of Seroprevalence and Prevalence of Influenza A Viruses (Subtypes H3N2, H3N8, and H1N1) in Dogs. Animals. 2024; 14(23):3467. Abstract
submitted by kickingbird at Dec, 11, 2024 from Animals. 2024; 14(23):3467 (via https://www.mdpi.com/2076-2615/14/23/3467)
Influenza A is a zoonotic disease that affects dogs. In this work, we performed a meta-analysis of the prevalence and seroprevalence of reports from all over the world. We found a combined seroprevalence ... Yong Zhou, etc.,al. Origin, spread, and interspecies transmission of a dominant genotype of BJ/94 lineage H9N2 avian influenza viruses with increased threat. Virus Evolution, veae106. Abstract
submitted by kickingbird at Dec, 11, 2024 from Virus Evolution, veae106 (via https://academic.oup.com/ve/advance-article/doi/10.1093/ve/v)
The H9N2 subtype of avian influenza viruses (AIVs) is widely prevalent in poultry and wild birds globally, with occasional transmission to humans. In comparison to other H9N2 lineages, the BJ/94 lineage ... Feng Wen, etc.,al. Novel human-type receptor-binding H5N1 virus in live poultry markets, China. The Lancet Microbe. Abstract
submitted by kickingbird at Dec, 11, 2024 from The Lancet Microbe (via https://www.sciencedirect.com/science/article/pii/S266652472)
Avian influenza viruses represent a considerable public health risk, with the capability to cross species barriers and cause severe disease in humans. The emergence of H5N1 subtype of highly pathogenic ... Ankerhold J, Kessler S, Beer M, Schwemmle M, Cimin. Replication Restriction of Influenza A(H5N1) Clade 2.3.4.4b Viruses by Human Immune Factor, 2023–2024. Emerg Infect Dis. 2025 Jan. Abstract
submitted by kickingbird at Dec, 11, 2024 from Emerg Infect Dis. 2025 Jan (via https://wwwnc.cdc.gov/eid/article/31/1/24-1236_article)
We show that human myxovirus resistance protein 1 (MxA) suppresses replication of highly pathogenic avian influenza A(H5N1) viruses isolated from mammals in vitro and in MxA-transgenic mice. However, H5N1 ... Sarsenov R, Babenko D, Kamalova D, Amirgazin A, Be. Complete genome sequence of a human influenza a virus (H1N1) detected in Kazakhstan in the fall of 2022. Microbiol Resour Announc. 2024 Dec 10:e0104024. Abstract
submitted by kickingbird at Dec, 11, 2024 from Microbiol Resour Announc. 2024 Dec 10:e0104024 (via https://journals.asm.org/doi/10.1128/mra.01040-24)
An Orthomyxoviridae Alphainfluenza virus Influenza A virus strain, A/Kazakhstan/Flu-H11-6/2022(H1N1), was isolated in Karaganda, Central Kazakhstan during a study of acute respiratory infections among ... Yin Y, Kan X, Miao X, Sun Y, Chen S, Qin T, Ding C. H5 subtype avian influenza virus induces Golgi apparatus stress response via TFE3 pathway to promote virus replication. PLoS Pathog. 2024 Dec 9;20(12):e1012748. Abstract
submitted by kickingbird at Dec, 10, 2024 from PLoS Pathog. 2024 Dec 9;20(12):e1012748 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
During infection, avian influenza virus (AIV) triggers endoplasmic reticulum (ER) stress, a well-established phenomenon in previous research. The Golgi apparatus, situated downstream of the ER and crucial ... Xia M, Huang P, Vago FS, Jiang W, Tan M. Pseudovirus nanoparticles targeting the receptor binding HA1 domains of influenza viruses elicited high HA1-specific antibody responses and protected mice against mortality caused by influenza virus c. Vaccine. 2024 Dec 7:126585. Abstract
submitted by kickingbird at Dec, 9, 2024 from Vaccine. 2024 Dec 7:126585 (via https://www.sciencedirect.com/science/article/abs/pii/S02644)
The continually high disease burden of influenza and the relatively low effectiveness of current influenza vaccines call for enhanced vaccine strategies. We previously generated unique S-HA1 pseudovirus ... Chothe SK, Srinivas S, Misra S, Nallipogu NC, Gilb. Marked Neurotropism and Potential Adaptation of H5N1 Clade 2.3.4.4.b Virus in Naturally Infected Domestic Cats. Emerg Microbes Infect. 2024 Dec 9:2440498. Abstract
submitted by kickingbird at Dec, 9, 2024 from Emerg Microbes Infect. 2024 Dec 9:2440498 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2024.2)
In April 2024, ten cats died in a rural South Dakota (SD) residence, showing respiratory and neurological symptoms. Necropsy and laboratory testing of two cats confirmed H5N1 clade 2.3.4.4b infection. ... 6502 items, 20/Page, Page[45/326][|<<] [|<] [41] [42] [43] [44] [45] [46] [47] [48] [49] [50] [>|] [>>|] |
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