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Bornholdt ZA, Prasad BV. X-ray structure of influenza virus NS1 effector domain. Nat Struct Mol Biol. 2006 May 21.  Abstract  
submitted by kickingbird at May, 30, 2006 from Nat Struct Mol Biol. 2006 May 21 (via http://www.nature.com/nsmb/journal/vaop/ncurrent/abs/nsmb109)
The nonstructural protein NS1 of influenza virus is an antagonist of host immune responses and is implicated in virulence. It has two domains, an N-terminal double-stranded RNA-binding domain (RBD) and ...

Park MS, Steel J, Garcia-Sastre A, Swayne D, Pales. Engineered viral vaccine constructs with dual specificity: Avian influenza and Newcastle disease. Proc Natl Acad Sci U S A. 2006 May 23;103(21):8203.  Full Text [Primary member] 
submitted by kickingbird at May, 30, 2006 from Proc Natl Acad Sci U S A. 2006 May 23;103(21):8203 (via http://www.pnas.org/cgi/content/full/103/21/8203)
Avian influenza viruses of the H5 and H7 hemagglutinin subtypes, and Newcastle disease virus (NDV), are important pathogens in poultry worldwide. Specifically, the highly pathogenic H5N1 avian influenza ...

Veits J, Wiesner D, Fuchs W, Hoffmann B, Granzow H. Newcastle disease virus expressing H5 hemagglutinin gene protects chickens against Newcastle disease and avian influenza. Proc Natl Acad Sci U S A. 2006 May 23;103(21):8197.  Full Text [Primary member] 
submitted by kickingbird at May, 30, 2006 from Proc Natl Acad Sci U S A. 2006 May 23;103(21):8197 (via http://www.pnas.org/cgi/content/full/103/21/8197)
Newcastle disease virus (NDV)-expressing avian influenza virus (AIV) hemagglutinin (HA) of subtype H5 was constructed by reverse genetics. A cloned full-length copy of the genome of the lentogenic NDV ...

Di Trani L, Bedini B, Donatelli I, Campitelli L, C. A sensitive one-step real-time PCR for detection of avian influenza viruses using a MGB probe and an internal positive control. BMC Infect Dis. 2006 May 25;6(1):87.  Full Text  
submitted by kickingbird at May, 30, 2006 from BMC Infect Dis. 2006 May 25;6(1):87 (via http://www.biomedcentral.com/1471-2334/6/87)
ABSTRACT: BACKGROUND: Avian influenza viruses (AIVs) are endemic in wild birds and their introduction and conversion to highly pathogenic avian influenza virus in domestic poultry is a cause of serious ...

Ye L, Sun Y, Lin J, Bu Z, Wu Q, Jiang S, Steinhaue. Antigenic properties of a transport-competent influenza HA/HIV Env chimeric protein. Virology. 2006 May 22.  Abstract  
submitted by kickingbird at May, 30, 2006 from Virology. 2006 May 22 (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&d)
The transmembrane subunit (gp41) of the HIV Env glycoprotein contains conserved neutralizing epitopes which are not well-exposed in wild-type HIV Env proteins. To enhance the exposure of these epitopes, ...

Chutinimitkul S, Bhattarakosol P, Srisuratanon S,. H5N1 Influenza A Virus and Infected Human Plasma. Emerg Infect Dis 2006 Jun edition.  Abstract  
submitted by kickingbird at May, 23, 2006 from Emerg Infect Dis 2006 Jun edition
To the Editor: Since January 2004, a total of 22 persons have been confirmed infected with avian influenza A virus (H5N1) in Thailand; 14 of these patients died. Three waves of outbreaks occurred during ...

LIU Guang-liang, etc.,al. Construction and transient expression of recombinant avian influenza virus with nucleoprotein gene. Chinese Journal of Veterinary Science and Tech.  Abstract  
submitted by kickingbird at May, 23, 2006 from Chinese Journal of Veterinary Science and Tech
The NP gene of the AIV A/Goose/Guangdong/1/96(H5N1) strain was amplified from a recombinant plasmid pMel-NP by PCR and subcloned into an eukaryotic expression vector pVAX1 and the recombinant vector was ...

JIN Ke; CHEN Hua; TAN Li-hua; YUAN You-hong; XIAO. The chest X-ray manifestations of children with highly pathogenic H5N1 avian influenza virus infection (a report of 1 final diagnosis case and 1 borderline case). Chinese Journal of Radiology.  Abstract  
submitted by kickingbird at May, 23, 2006 from Chinese Journal of Radiology
Objective To describe the chest X-ray manifestations of children with highly pathogenic H5N1 avian influenza virus infection.Methods The pulmonary X-ray findings in 1 patient was confirmed by the World ...

Dimmock NJ, Marriott AC. In vivo antiviral activity: defective interfering virus protects better against virulent Influenza A virus than a virulent virus. J Gen Virol. 2006 May;87(Pt 5):1259-65.  Abstract  
submitted by kickingbird at Apr, 26, 2006 from J Gen Virol. 2006 May;87(Pt 5):1259-65
A defective interfering (DI) virus differs from the infectious virus from which it originated in having at least one major deletion in its genome. Such DI genomes are replicated only in cells infected ...

Mann A, Marriott AC, Balasingam S, Lambkin R, Oxford JS, Dimmock NJ. Interfering vaccine (defective interfering influenza A virus) protects ferrets from influenza, and allows them to develop solid immunity to reinfection. Vaccine. 2006 Mar 20; [Epub ahead of print].  Abstract  
submitted by kickingbird at Apr, 26, 2006 from Vaccine. 2006 Mar 20; [Epub ahead of print]
Defective interfering (DI) virus RNAs result from major deletions in full-length viral RNAs that occur spontaneously during de novo RNA synthesis. These RNAs are packaged into virions that are by definition ...

Chan AY, Vreede FT, Smith M, Engelhardt OG, Fodor E. Influenza virus inhibits RNA polymerase II elongation. Virology. 2006 Apr 17; [Epub ahead of print].  Abstract  
submitted by kickingbird at Apr, 26, 2006 from Virology. 2006 Apr 17; [Epub ahead of print]
The influenza virus RNA-dependent RNA polymerase interacts with the serine-5 phosphorylated carboxy-terminal domain (CTD) of the large subunit of RNA polymerase II (Pol II). It was proposed that this interaction ...

Loens K, Goossens H, de Laat C, Foolen H, Oudshoorn P, Pattyn S, Sillekens P, Ieven M. Detection of rhinoviruses by tissue culture and two independent amplification techniques, nucleic acid sequence-based amplification and reverse transcription-PCR, in children with acute respiratory in. J Clin Microbiol. 2006 Jan;44(1):166-71.  Abstract  
submitted by kickingbird at Mar, 29, 2006 from J Clin Microbiol. 2006 Jan;44(1):166-71
Five hundred seventeen consecutive nasopharyngeal aspirates were collected between October 1998 and May 1999 for episodes of acute respiratory tract infections in children presenting at the University ...

Widjaja L, Ilyushina N, Webster RG, Webby RJ. Molecular changes associated with adaptation of human influenza A virus in embryonated chicken eggs. Virology. 2006 Mar 15.  Abstract  
submitted by kickingbird at Mar, 29, 2006 from Virology. 2006 Mar 15
Failure to isolate A/Fujian/411/2002 (H3N2) in embryonated chicken eggs resulted in its absence from the 2003/2004 vaccine. We analyzed the adaptation of this virus in eggs during serial passages in the ...

Xie Z, Pang YS, Liu J, Deng X, Tang X, Sun J, Khan MI. A multiplex RT-PCR for detection of type A influenza virus and differentiation of avian H5, H7, and H9 hemagglutinin subtypes. Mol Cell Probes. 2006 Mar 14; [Epub ahead of print].  Abstract  
submitted by kickingbird at Mar, 21, 2006 from Mol Cell Probes. 2006 Mar 14; [Epub ahead of print]
Guangxi Veterinary Research Institute, 51 You Ai North Road, Nanning, Guangxi 530001, People´s Republic of China.A multiplex reverse transcriptase-polymerase chain reaction (mRT-PCR) was developed ...

KAMADA M , Nagai T, Kumagai T, Igarashi M, et al. Efficacy of inactivated trivalent influenza vaccine in alleviating the febrile illness of culture-confirmed influenza in children in the 2000-2001 influenza season. Vaccine. 2006.  Abstract  
submitted by kickingbird at Mar, 19, 2006 from Vaccine. 2006
Nagai Pediatric Clinic, 2-20 Akanechou, Takamatsu, Kagawa 760-0002, Japan.During the 2000/2001 influenza season in Japan, children ranging in age from 6 months to 13 years with fever exceeding 37.5 degrees ...

SCHEERLINCK JP , Gekas S, Yen HH, Edwards S, et al. Local immune responses following nasal delivery of an adjuvanted influenza vaccine. Vaccine. 2006.  Abstract  
submitted by kickingbird at Mar, 19, 2006 from Vaccine. 2006
Centre for Animal Biotechnology, University of Melbourne, Parkville, 3010 Vic., Australia.A key barrier to producing effective nasal immunisations is the low efficiency of uptake of vaccines across the ...

HENTER JI , Chow CB, Leung CW, Lau YL, et al. Cytotoxic therapy for severe avian influenza A (H5N1) infection. Lancet. 2006;367:870-3.  Abstract  
submitted by kickingbird at Mar, 19, 2006 from Lancet. 2006;367:870-3
Childhood Cancer Research Unit, Department of Woman and Child Health, Karolinska Institutet, Karolinska University Hospital Q6:05, SE-171 76 Stockholm, Sweden.The mortality rate in documented avian influenza ...

HU YC , Luo YL, Ji WT, Chulu JL, et al. Dual expression of the HA protein of H5N2 avian influenza virus in a baculovirus system. J Virol Methods. 2006.  Abstract  
submitted by kickingbird at Mar, 19, 2006 from J Virol Methods. 2006
Department of Chemical Engineering, National Tsing Hua University, Hsinchu, Taiwan.Baculovirus/insect cell system is used widely for recombinant protein production. The hemagglutinin (HA) gene of H5N2 ...

MATIKAINEN S , Siren J, Tissari J, Veckman V, et al. Tumor Necrosis Factor Alpha Enhances Influenza A Virus-Induced Expression of Antiviral Cytokines by Activating RIG-I Gene Expression. J Virol. 2006;80:3515-22.  Abstract  
submitted by kickingbird at Mar, 19, 2006 from J Virol. 2006;80:3515-22
Unit of Excellence in Immunotoxicology, Finnish Institute of Occupational Health (FIOH), Topeliuksenkatu 41b, 00250 Helsinki, Finland. sampsa.matikainen@ttl.fi.Epithelial cells of the lung are the primary ...

NOBUSAWA E , Sato K. Comparison of the mutation rates of human influenza a and B viruses. J Virol. 2006;80:3675-8.  Abstract  
submitted by kickingbird at Mar, 19, 2006 from J Virol. 2006;80:3675-8
Department of Microbiology and Infection, Nagoya City University Graduate School of Medical Science, Kawasumi 1, Mizuho-cho, Mizuho-ku, Nagoya City 467-8601, Japan. nobusawa@med.nagoya-cu.ac.jp.Human influenza ...

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