VEITS J, Weber S, Stech O, Breithaupt A, et al.. Avian influenza virus hemagglutinins H2, H4, H8, and H14 support a highly pathogenic phenotype. Proc Natl Acad Sci U S A. 2012. Abstract
submitted by kickingbird at Feb, 16, 2012 from Proc Natl Acad Sci U S A. 2012 (via http://www.pnas.org/content/109/7/2579.long)
High-pathogenic avian influenza viruses (HPAIVs) evolve from low-pathogenic precursors specifying the HA serotypes H5 or H7 by acquisition of a polybasic HA cleavage site. As the reason for this serotype ... WANG M, Tscherne DM, McCullough C, Caffrey M, et a. Residue Y161 of influenza hemagglutinin is involved in viral recognition of sialylated complexes from different hosts. J Virol. 2012 Feb 1. Abstract
submitted by kickingbird at Feb, 16, 2012 from J Virol. 2012 Feb 1 (via http://www.ncbi.nlm.nih.gov/pubmed/22301136)
Influenza A virus glycoprotein hemagglutinin (HA) binds to host cell surface sialic acid (SA)-terminated sugars in glycoproteins to initiate viral entry. It is thought that avian influenza viruses preferentially ... MEUNIER I, von Messling V. PB1-F2 Modulates Early Host Responses but Does not Affect the Pathogenesis of H1N1 Seasonal Influenza Virus. J Virol. 2012 Feb 8.. Abstract
submitted by kickingbird at Feb, 16, 2012 from J Virol. 2012 Feb 8. (via http://www.ncbi.nlm.nih.gov/pubmed/22318139)
In the context of infections with highly pathogenic influenza A viruses the PB1-F2 protein contributes to virulence and enhances lung inflammation. In contrast, its role in the pathogenesis of seasonal ... VAN STRY M, Oguin T, Cheloufi S, Vogel P, et al.. Enhanced Susceptibility to Influenza A Virus of Ago1/3 Double Null Mice. J Virol. 2012 Feb 8.. Abstract
submitted by kickingbird at Feb, 16, 2012 from J Virol. 2012 Feb 8. (via http://www.ncbi.nlm.nih.gov/pubmed/22318144)
RNAi is a critical component of many cellular anti-viral responses in plants, invertebrates, and mammals. However, its in vivo role in host protection from the negative sense RNA virus Influenza Type A ... PICA N, Chou YY, Bouvier NM, Palese P, et al.. Transmission of Influenza B viruses in the Guinea Pig. J Virol. 2012 Feb 1. Abstract
submitted by kickingbird at Feb, 16, 2012 from J Virol. 2012 Feb 1 (via http://www.ncbi.nlm.nih.gov/pubmed/22301149)
Epidemic influenza is typically caused by infection of viruses of the A and B type and can result in substantial morbidity and mortality during a given season. Here we demonstrate that influenza B viruses ... MENEGHESSO S, Vanderlinden E, Stevaert A, McGuigan. Synthesis and biological evaluation of pyrimidine nucleoside monophosphate prodrugs targeted against influenza virus. Antiviral Res. 2012. Abstract
submitted by kickingbird at Feb, 16, 2012 from Antiviral Res. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22306172)
Uridine-based nucleoside analogues have often been found to have relatively poor antiviral activity. Enzymatic assays, evaluating inhibition of influenza virus RNA polymerase, revealed that some uridine ... FAN K, Jia Y, Wang S, Li H, et al. Role of Itk signaling in the interaction between influenza A virus and T cells. J Gen Virol. 2012. Abstract
submitted by kickingbird at Feb, 16, 2012 from J Gen Virol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22302878)
Although T cell-mediated immune response to influenza virus has been extensively studied, little information is available on direct interaction between influenza virus and T cells that pertains to severe ... McCullers JA, Hayden FG. Fatal Influenza B Infections: Time to Reexamine Influenza Research Priorities. J Infect Dis 2012 Jan 30. Abstract
submitted by kickingbird at Feb, 2, 2012 from J Infect Dis 2012 Jan 30 (via http://jid.oxfordjournals.org/content/early/2012/01/28/infdi)
Influenza A viruses (IAVs) are zoonotic pathogens that sometimes establish long-term lineages in humans and other mammalian hosts. New introductions of influenza genes or whole viruses from animal reservoirs ... Yuan Fang, David Banner, Alyson A. Kelvin, Stephen. Seasonal H1N1 Influenza Virus Infection Induces Cross-Protective Pandemic H1N1 Virus Immunity through a CD8-Independent, B Cell-Dependent Mechanism. J. Virol. February 2012 86:2229-2238. Abstract
submitted by kickingbird at Feb, 2, 2012 from J. Virol. February 2012 86:2229-2238 (via http://jvi.asm.org/content/86/4/2229.abstract)
During the 2009 H1N1 influenza virus pandemic (pdmH1N1) outbreak, it was found that most individuals lacked antibodies against the new pdmH1N1 virus, and only the elderly showed anti-hemagglutinin (anti-HA) ... Li Lin, Yang Li, Hyun-Mi Pyo, Xinya Lu, Sathya N.. Identification of RNA Helicase A as a Cellular Factor That Interacts with Influenza A Virus NS1 Protein and Its Role in the Virus Life Cycle. J. Virol. February 2012 86:1942-1954. Abstract
submitted by kickingbird at Feb, 2, 2012 from J. Virol. February 2012 86:1942-1954 (via http://jvi.asm.org/content/86/4/1942.abstract)
Influenza A virus NS1 protein has multiple functions in the infected cell during the virus life cycle. Identification of novel cellular factors that interact with NS1 and understanding their functions ... Xiaohui Fan, Huachen Zhu, Boping Zhou, David K. Sm. Emergence and Dissemination of a Swine H3N2 Reassortant Influenza Virus with 2009 Pandemic H1N1 Genes in Pigs in China. J. Virol. February 2012 86:2375-2378;. Abstract
submitted by kickingbird at Feb, 2, 2012 from J. Virol. February 2012 86:2375-2378; (via http://jvi.asm.org/content/86/4/2375.abstract)
The 2009 pandemic influenza virus (pdm/09) has been frequently introduced to pigs and has reassorted with other swine viruses. Recently, H3N2 reassortants with pdm/09-like internal genes were isolated ... Skowronski DM, De Serres G, Janjua NZ, Gardy JL, G. Cross-reactive antibody to swine influenza A(H3N2) subtype virus in children and adults before and after immunisation with 2010/11 trivalent inactivated influenza vaccine in Canada, August to November. Euro Surveill. 2012;17(4):pii=20066. Full Text
submitted by kickingbird at Jan, 28, 2012 from Euro Surveill. 2012;17(4):pii=20066 (via http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=2)
In pre- and post-immunisation sera from children (17–120 months-old) and adults (20–59 years-old) immunised with 2010/11 trivalent inactivated influenza vaccine, we assessed age-related patterns of sero-susceptibility ... Eefje J. A. Schrauwen,etc.,al. The multi basic cleavage site in H5N1 virus is critical for systemic spread along the olfactory and hematogenous routes in ferrets. 2012, doi: 10.1128/?JVI.06828-11. Abstract
submitted by kickingbird at Jan, 28, 2012 from 2012, doi: 10.1128/?JVI.06828-11 (via http://jvi.asm.org/content/early/2012/01/18/JVI.06828-11.sho)
The route by which highly pathogenic avian influenza (HPAI) H5N1 virus spreads systemically, including the central nervous system (CNS), is largely unknown in mammals. Especially the olfactory route, which ... FONTANA J, Cardone G, Heymann JB, Winkler DC, et a. Structural changes in influenza virus at low pH characterized by cryo-electron tomography. J Virol. 2012. Abstract
submitted by kickingbird at Jan, 24, 2012 from J Virol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22258245)
Influenza virus enters host cells by endocytosis. The low pH of endosomes triggers conformational changes in hemagglutinin (HA) that mediate fusion of the viral and endosomal membranes. We have used cryo-electron ... KOBAYASHI Y, Suzuki Y. Evidence for N-glycan shielding of antigenic sites during evolution of human influenza A virus hemagglutinin. J Virol. 2012. Abstract
submitted by kickingbird at Jan, 24, 2012 from J Virol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22258255)
After the emergence of influenza A viruses in the human population, the number of N-glycosylation sites (NGS) in the globular head region of hemagglutinin (HA) has increased continuously for several decades. ... KANCHANA S, Kanchana S, Chuntrakul C, Malathum K,. Pandemic (H1N1) 2009 virus infection: persistent viral shedding after Oseltamivir treatment. J Infect. 2011;63:295-9.. Abstract
submitted by kickingbird at Jan, 24, 2012 from J Infect. 2011;63:295-9. (via http://www.ncbi.nlm.nih.gov/pubmed/21840339)
OBJECTIVES:
To study pandemic (H1N1) 2009 virological outcomes after Oseltamivir treatment in confirmed cases of pandemic (H1N1) 2009 virus infections. A hospital-based cohort study was conducted in ... BRUCE EA, Abbink TE, Wise HM, Rollason R, et al. Release of filamentous and spherical influenza A virus is not restricted by tetherin. J Gen Virol. 2012. Abstract
submitted by kickingbird at Jan, 24, 2012 from J Gen Virol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22258861)
The cellular protein tetherin is thought to act as a 'leash' that anchors many enveloped viruses to the plasma membrane and prevents their release. We found that replication of multiple strains of influenza ... KOERNER I, Matrosovich MN, Haller O, Staeheli P, e. Altered receptor specificity and fusion activity of the hemagglutinin contribute to high virulence of a mouse-adapted influenza A virus. J Gen Virol. 2012.. Abstract
submitted by kickingbird at Jan, 24, 2012 from J Gen Virol. 2012. (via http://www.ncbi.nlm.nih.gov/pubmed/22258863)
The viral hemagglutinin (HA) and the viral polymerase complex determine the replication fitness of a highly virulent variant of influenza A virus strain A/PR/8/34 (designated hvPR8) and its high pathogenicity ... STONER TD, Krauss S, Turner JC, Seiler P, et al. Susceptibility of avian influenza viruses of the N6 subtype to the neuraminidase inhibitor oseltamivir. Antiviral Res. 2012.. Abstract
submitted by kickingbird at Jan, 24, 2012 from Antiviral Res. 2012. (via http://www.ncbi.nlm.nih.gov/pubmed/22252168)
Avian influenza viruses are a source of genetic material that can be transmitted to humans through direct introduction or reassortment. Although there is a wealth of information concerning global monitoring ... Hongxing Hu,etc.,al. A Human Antibody Recognizing a Conserved Epitope of H5 Hemagglutinin Broadly Neutralizes Highly Pathogenic Avian Influenza H5N1 Viruses. J Virol, published online Jan 11. Abstract
submitted by kickingbird at Jan, 21, 2012 from J Virol, published online Jan 11 (via http://jvi.asm.org/content/early/2012/01/04/JVI.06665-11.sho)
Influenza A virus infection is a persistent threat to public health worldwide, due to its ability to evade immune surveillance through rapid genetic drift and shift. Current vaccines against influenza ... 5584 items, 20/Page, Page[220/280][|<<] [|<] [211] [212] [213] [214] [215] [216] [217] [218] [219] [220] [>|] [>>|] |
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