KISO M, Ozawa M, Le MT, Imai H, et al. Effect of an asparagine-to-serine mutation at position 294 in neuraminidase on the pathogenicity of highly pathogenic H5N1 influenza A virus. J Virol. 2011 Mar 2. Abstract
submitted by kickingbird at Mar, 9, 2011 from J Virol. 2011 Mar 2 (via http://www.ncbi.nlm.nih.gov/pubmed/21367898)
Like the histidine-to-tyrosine substitution at position 274 in neuraminidase (NA H274Y), an asparagine-to-serine mutation at position 294 in this protein (NA N294S) confers oseltamivir resistance to highly ... BUCASAS KL, Franco LM, Shaw CA, Bray MS, et al. Early Patterns of Gene Expression Correlate With the Humoral Immune Response to Influenza Vaccination in Humans. J Infect Dis. 2011 Feb 28. Abstract
submitted by kickingbird at Mar, 9, 2011 from J Infect Dis. 2011 Feb 28 (via http://www.ncbi.nlm.nih.gov/pubmed/21357945)
Background.?Annual vaccination is the primary means for preventing influenza. However, great interindividual variability exists in vaccine responses, the cellular events that take place in vivo after vaccination ... CHENG VC, Chan JF, Wen X, Wu WL, etc., al. Infection Of Immunocompromised Human By Avian H9n2 Influenza A Virus. J Infect. 2011 Feb 25. Abstract
submitted by kickingbird at Mar, 9, 2011 from J Infect. 2011 Feb 25 (via http://www.ncbi.nlm.nih.gov/pubmed/21356238)
Avian influenza A (H9N2) virus is transmitted sporadically from avian species to human causing mild diseases in immunocompetent person. We report two immunocompromised patients cases of human infection ... LI J, Li Y, Hu Y, Chang G, et al. PB1-mediated Virulence Attenuation of H5N1 Influenza Virus in Mice is Associated with PB2. J Gen Virol. 2011 Mar 2. Abstract
submitted by kickingbird at Mar, 9, 2011 from J Gen Virol. 2011 Mar 2 (via http://www.ncbi.nlm.nih.gov/pubmed/21367983)
H5N1 avian influenza viruses demonstrate different phenotypes, such as pathogenicity after one or serial passage(s) in mammalian hosts or cells. To establish the molecular basis of these phenotypes, we ... SAKABE S, Iwatsuki-Horimoto K, Takano R, Nidom CA,. Cytokine production by primary human macrophages infected with highly pathogenic H5N1 or pandemic H1N1 2009 influenza viruses. J Gen Virol. 2011 Mar 2.. Abstract
submitted by kickingbird at Mar, 9, 2011 from J Gen Virol. 2011 Mar 2. (via http://www.ncbi.nlm.nih.gov/pubmed/21367984)
Highly pathogenic H5N1 avian influenza viruses have caused infection in humans, with a high mortality rate, since 1997. While the pathogenesis of this infection is not completely understood, hypercytokinemia ... SIMULUNDU E, Ishii A, Igarashi M, Mweene AS, et al. Characterization of influenza A viruses isolated from wild waterfowls in Zambia. J Gen Virol. 2011 Mar 2. Abstract
submitted by kickingbird at Mar, 9, 2011 from J Gen Virol. 2011 Mar 2 (via http://www.ncbi.nlm.nih.gov/pubmed/21367986)
Although the quest to clarify the role of wild birds in the spread of the highly pathogenic H5N1 avian influenza virus (AIV) has yielded considerable data on AIVs in wild birds worldwide, information regarding ... OZAWA M, Basnet S, Burley LM, Neumann G, et al. Impact of amino acid mutations in PB2, PB1-F2, and NS1 on the replication and pathogenicity of pandemic (H1N1) 2009 influenza viruses. J Virol. 2011 Feb 16. Abstract
submitted by kickingbird at Mar, 4, 2011 from J Virol. 2011 Feb 16 (via http://www.ncbi.nlm.nih.gov/pubmed/21325408)
Here, we assessed the effect of PB1-F2 and NS1 mutations known to increase the pathogenicity of influenza viruses on the replication and pathogenicity in mice of pandemic (H1N1) 2009 influenza viruses. ... SCHWARTZ JA, Buonocore L, Suguitan A Jr, Hunter M,. Vesicular Stomatitis Virus-Based H5N1 Avian Influenza Vaccines Induce Potent Cross-Clade Neutralizing Antibodies in Rhesus Macaques. J Virol. 2011 Feb 16. Abstract
submitted by kickingbird at Mar, 4, 2011 from J Virol. 2011 Feb 16 (via http://www.ncbi.nlm.nih.gov/pubmed/21325423)
We analyzed the ability of a vaccine vector based on vesicular stomatitis virus (VSV) to induce a neutralizing antibody (nAb) response to avian influenza viruses (AIV) in rhesus macaques. Animals vaccinated ... RAMOS I, Bernal-Rubio D, Durham N, Belicha-Villanu. Effects of receptor binding specificity of avian influenza virus on the human innate immune response. J Virol. 2011 Feb 23. Abstract
submitted by kickingbird at Mar, 4, 2011 from J Virol. 2011 Feb 23 (via http://www.ncbi.nlm.nih.gov/pubmed/21345953)
Humans infected by H5N1 highly pathogenic avian influenza virus (HPAIV) present unusually high serum concentrations of proinflammatory cytokines and chemokines, which are believed to contribute to the ... CHEN LF, Dailey NJ, Rao AK, Fleischauer AT, et al.. Cluster of Oseltamivir-Resistant 2009 Pandemic Influenza A (H1N1) Virus Infections on a Hospital Ward among Immunocompromised Patients--North Carolina, 2009. J Infect Dis. 2011 Mar;203(6):838-46. Abstract
submitted by kickingbird at Mar, 4, 2011 from J Infect Dis. 2011 Mar;203(6):838-46 (via http://www.ncbi.nlm.nih.gov/pubmed/21343149)
Background.?Oseltamivir resistance among 2009 pandemic influenza A (H1N1) viruses (pH1N1) is rare. We investigated a cluster of oseltamivir-resistant pH1N1 infections in a hospital ward. Methods.?We reviewed ... SCHRAUWEN EJ, Bestebroer TM, Munster VJ, De Wit E,. Insertion of a multi basic cleavage site in the hemagglutinin of a human influenza H3N2 virus does not increase pathogenicity in ferrets. J Gen Virol. 2011 Feb 23. Abstract
submitted by kickingbird at Mar, 4, 2011 from J Gen Virol. 2011 Feb 23 (via http://www.ncbi.nlm.nih.gov/pubmed/21346026)
A multibasic cleavage site (MBCS) in the hemagglutinin (HA) protein of influenza A virus is a key determinant of pathogenicity in chickens, and distinguishes highly pathogenic avian influenza (HPAI) viruses ... WANITCHANG A, Patarasirin P, Jengarn J, Jongkaewwa. Atypical characteristics of nucleoprotein of pandemic influenza virus H1N1 and their roles in reassortment restriction.. Arch Virol. 2011. Abstract
submitted by kickingbird at Mar, 4, 2011 from Arch Virol. 2011 (via http://www.ncbi.nlm.nih.gov/pubmed/21340741)
Sequence analysis of the nucleoprotein (NP) of swine-origin influenza virus H1N1 (S-OIV) reveals a number of atypical characteristics including an early start codon and a highly conserved, non-aromatic ... Yipeng Sun,etc.,al. High genetic compatibility and increased pathogenicity of reassortants derived from avian H9N2 and pandemic H1N1/2009 influenza viruses. PNAS doi: 10.1073/pnas.1019109108. Abstract
submitted by kickingbird at Mar, 4, 2011 from PNAS doi: 10.1073/pnas.1019109108 (via http://www.pnas.org/content/early/2011/02/23/1019109108.abst)
H9N2 influenza viruses have been circulating worldwide in multiple avian species and repeatedly infecting mammals, including pigs and humans, posing a significant threat to public health. The coexistence ... Puzelli S, Facchini M, De Marco MA, Palmieri A, Sp. Molecular surveillance of pandemic influenza A(H1N1) viruses circulating in Italy from May 2009 to February 2010: association between haemagglutinin mutations and clinical outcome. Euro Surveill. 2010;15(43):pii=19696. Abstract
submitted by kickingbird at Oct, 28, 2010 from Euro Surveill. 2010;15(43):pii=19696 (via http://www.eurosurveillance.org:80/ViewArticle.aspx?ArticleI)
Haemagglutinin sequences of pandemic influenza A(H1N1) viruses circulating in Italy were examined, focusing on amino acid changes at position 222 because of its suggested pathogenic relevance. Among ... Wu J, Liu SZ, Dong SS, Dong XP, Zhang WL, Lu M, Li. Safety and immunogenicity of adjuvanted inactivated split-virion and whole-virion influenza A (H5N1) vaccines in children: A phase I-II randomized trial. Vaccine. 2010 Jul 15. Abstract
submitted by kickingbird at Jul, 25, 2010 from Vaccine. 2010 Jul 15 (via http://www.ncbi.nlm.nih.gov/pubmed/20638454)
OBJECTIVE: Highly pathogenic avian influenza A virus H5N1 has the potential to cause a pandemic. Many prototype pandemic influenza A (H5N1) vaccines had been developed and well evaluated in adults in recent ... WU J, Li W, Wang HQ, Chen JT, et al.. A Rapid Immune Response to 2009 Influenza A(H1N1) Vaccines in Adults: A Randomized, Double-Blind, Controlled Trial. J Infect Dis. 2010 Jul 15. Abstract
submitted by kickingbird at Jul, 25, 2010 from J Infect Dis. 2010 Jul 15 (via http://www.ncbi.nlm.nih.gov/pubmed/20632888)
A double-blind, randomized, controlled trial involving 706 adults was conducted to evaluate the immunogenicity and safety of different dosages of whole-virion or split-virion H1N1 influenza vaccines with ... Mueller SN, Langley WA, Li G, García-Sastre A, Web. Qualitatively Different Memory CD8+ T Cells Are Generated after Lymphocytic Choriomeningitis Virus and Influenza Virus Infections. J Immunol. 2010 Jul 16.. Abstract
submitted by kickingbird at Jul, 25, 2010 from J Immunol. 2010 Jul 16. (via http://www.ncbi.nlm.nih.gov/pubmed/20639484)
Viral infections often induce robust T cell responses that are long-lived and protective. However, it is unclear to what degree systemic versus mucosal infection influences the generation of effector and ... SMEE DF, Hurst BL, Wong MH, Tarbet EB, et al. Combinations of oseltamivir and peramivir for the treatment of influenza A (H1N1) virus infections in cell culture and in mice. Antiviral Res. 2010 Jul 13. Abstract
submitted by kickingbird at Jul, 25, 2010 from Antiviral Res. 2010 Jul 13 (via http://www.ncbi.nlm.nih.gov/pubmed/20633577)
Oseltamivir and peramivir are being considered for combination treatment of serious influenza virus infections in humans. Both compounds are influenza virus neuraminidase inhibitors, and since peramivir ... SUNDARARAJAN A, Ganapathy R, Huan L, Dunlap JR, et. Influenza virus variation in susceptibility to inactivation by pomegranate polyphenols is determined by envelope glycoproteins. Antiviral Res. 2010 Jul 14. Abstract
submitted by kickingbird at Jul, 25, 2010 from Antiviral Res. 2010 Jul 14 (via http://www.ncbi.nlm.nih.gov/pubmed/20637243)
Pomegranates have high levels of polyphenols (PPs) and may be a rich source of compounds with antiviral activity. We evaluated the direct anti-influenza activity of three commercially available pomegranate ... Bin Wu,etc.,al. New Evidence Suggests Southern China as a Common Source of Multiple Clusters of Highly Pathogenic H5N1 Avian Influenza Virus. The Journal of Infectious Diseases 2010. Abstract
submitted by kickingbird at Jun, 27, 2010 from The Journal of Infectious Diseases 2010 (via http://www.journals.uchicago.edu:80/doi/abs/10.1086/653709)
Highly pathogenic H5N1 avian influenza is considered an avian disease, although there is some evidence of limited human‐to‐human transmission of the virus. A global effort is underway to control or eradicate ... 5165 items, 20/Page, Page[206/259][|<<] [|<] [201] [202] [203] [204] [205] [206] [207] [208] [209] [210] [>|] [>>|] |
Related Pages:
Browse by Category
Learn about the flu news, articles, events and more
Subscribe to the weekly F.I.C newsletter!
|
- 
