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2024-4-19 15:03:10
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KOERNER I, Matrosovich MN, Haller O, Staeheli P, e. Altered receptor specificity and fusion activity of the hemagglutinin contribute to high virulence of a mouse-adapted influenza A virus. J Gen Virol. 2012..  Abstract  
submitted by kickingbird at Jan, 24, 2012 from J Gen Virol. 2012. (via http://www.ncbi.nlm.nih.gov/pubmed/22258863)
The viral hemagglutinin (HA) and the viral polymerase complex determine the replication fitness of a highly virulent variant of influenza A virus strain A/PR/8/34 (designated hvPR8) and its high pathogenicity ...

STONER TD, Krauss S, Turner JC, Seiler P, et al. Susceptibility of avian influenza viruses of the N6 subtype to the neuraminidase inhibitor oseltamivir. Antiviral Res. 2012..  Abstract  
submitted by kickingbird at Jan, 24, 2012 from Antiviral Res. 2012. (via http://www.ncbi.nlm.nih.gov/pubmed/22252168)
Avian influenza viruses are a source of genetic material that can be transmitted to humans through direct introduction or reassortment. Although there is a wealth of information concerning global monitoring ...

Hongxing Hu,etc.,al. A Human Antibody Recognizing a Conserved Epitope of H5 Hemagglutinin Broadly Neutralizes Highly Pathogenic Avian Influenza H5N1 Viruses. J Virol, published online Jan 11.  Abstract  
submitted by kickingbird at Jan, 21, 2012 from J Virol, published online Jan 11 (via http://jvi.asm.org/content/early/2012/01/04/JVI.06665-11.sho)
Influenza A virus infection is a persistent threat to public health worldwide, due to its ability to evade immune surveillance through rapid genetic drift and shift. Current vaccines against influenza ...

Jeffrey Shamana, Marc Lipsitch. The El Nino–Southern Oscillation (ENSO)–pandemic Influenza connection: Coincident or causal?. Proc Natl Acad Sci, published online Jan 17.  Full Text  
submitted by kickingbird at Jan, 21, 2012 from Proc Natl Acad Sci, published online Jan 17 (via http://www.pnas.org/content/early/2012/01/11/1107485109.shor)
We find that the four most recent human influenza pandemics (1918, 1957, 1968, and 2009), all of which were first identified in boreal spring or summer, were preceded by La Ni?a conditions in the equatorial ...

Crossley B, Hietala S, Hunt T, Benjamin G, Martine. Pandemic (H1N1) 2009 in Captive Cheetah. Emerg Infect Dis. 2012 Feb.  Abstract  
submitted by kickingbird at Jan, 21, 2012 from Emerg Infect Dis. 2012 Feb (via http://wwwnc.cdc.gov/eid/article/18/2/11-1245_article.htm)
We describe virus isolation, full genome sequence analysis, and clinical pathology in ferrets experimentally inoculated with pandemic (H1N1) 2009 virus recovered from a clinically ill captive cheetah that ...

DeVries etc., al. Neuraminidase H275Y and hemagglutinin D222G mutations in a fatal case of 2009 pandemic influenza A (H1N1) virus infection. Influenza and Other Respiratory Viruses DOI: 10.11.  Abstract  
submitted by kickingbird at Jan, 21, 2012 from Influenza and Other Respiratory Viruses DOI: 10.11 (via http://onlinelibrary.wiley.com/doi/10.1111/j.1750-2659.2011.)
Oseltamivir-resistant 2009 H1N1 influenza virus infections associated with neuraminidase (NA) H275Y have been identified sporadically. Strains possessing the hemagglutinin (HA) D222G mutation have been ...

LEKCHAROENSUK P, Wiriyarat W, Petcharat N, Lekchar. Cloned cDNA of A/swine/Iowa/15/1930 internal genes as a candidate backbone for reverse genetics vaccine against influenza A viruses.. Vaccine. 2012.  Abstract  
submitted by kickingbird at Jan, 16, 2012 from Vaccine. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22230579)
Reverse genetics viruses for influenza vaccine production usually utilize the internal genes of the egg-adapted A/Puerto Rico/8/34 (PR8) strain. This egg-adapted strain provides high production yield in ...

HU Y, Jin Y, Han D, Zhang G, et al.. Mast cell-induced lung injury in mice infected with H5N1 influenza virus. J Virol. 2012..  Abstract  
submitted by kickingbird at Jan, 16, 2012 from J Virol. 2012. (via http://www.ncbi.nlm.nih.gov/pubmed/22238293)
Although an important role for mast cells in several viral infections has been demonstrated, its role in the invasion of highly pathogenic H5N1 influenza virus is unknown. In the present study, we demonstrated ...

HU H, Voss J, Zhang G, Buchy P, et al. A Human Antibody Recognizing a Conserved Epitope of H5 Hemagglutinin Broadly Neutralizes Highly Pathogenic Avian Influenza H5N1 Viruses. J Virol. 2012..  Abstract  
submitted by kickingbird at Jan, 16, 2012 from J Virol. 2012. (via http://www.ncbi.nlm.nih.gov/pubmed/22238297)
Influenza A virus infection is a persistent threat to public health worldwide, due to its ability to evade immune surveillance through rapid genetic drift and shift. Current vaccines against influenza ...

OHKURA T, Kikuchi Y, Kono N, Itamura S, et al. Epitope mapping of neutralizing monoclonal antibody in avian influenza A H5N1 virus hemagglutinin.. Biochem Biophys Res Commun. 2011.  Abstract  
submitted by kickingbird at Jan, 16, 2012 from Biochem Biophys Res Commun. 2011 (via http://www.ncbi.nlm.nih.gov/pubmed/22226969)
The global spread of highly pathogenic avian influenza A H5N1 viruses raises concerns about more widespread infection in the human population. Pre-pandemic vaccine for H5N1 clade 1 influenza viruses has ...

Trevennec, K., Leger, L., Lyazrhi, F., Baudon, E.,. Transmission of pandemic influenza H1N1 (2009) in Vietnamese swine in 2009–2010. Influenza and Other Respiratory Viruses. doi: 10.1.  Abstract  
submitted by kickingbird at Jan, 7, 2012 from Influenza and Other Respiratory Viruses. doi: 10.1 (via http://onlinelibrary.wiley.com/doi/10.1111/j.1750-2659.2011.)
Background The pandemic of 2009 was caused by an H1N1 (H1N1pdm) virus of swine origin. This pandemic virus has repeatedly infected swine through reverse zoonosis, although the extent of such infection ...

Seema S.,etc.,al. Eurasian-Origin Gene Segments Contribute to the Transmissibility, Aerosol Release, and Morphology of the 2009 Pandemic H1N1 Influenza Virus. PLoS pathogens.  Full Text  
submitted by kickingbird at Jan, 7, 2012 from PLoS pathogens (via http://www.plospathogens.org/article/info%3Adoi%2F10.1371%2F)
The epidemiological success of pandemic and epidemic influenza A viruses relies on the ability to transmit efficiently from person-to-person via respiratory droplets. Respiratory droplet (RD) transmission ...

Susanna Esposito, Cristina Daleno, Claudia Tagliab. Antibody response of healthy children to pandemic A/H1N1/2009 influenza virus. Virology Journal 2011, 8:563 doi:10.1186/1743-422X.  Abstract  
submitted by kickingbird at Jan, 7, 2012 from Virology Journal 2011, 8:563 doi:10.1186/1743-422X (via http://www.virologyj.com/content/8/1/563/abstract)
Background Little is known about the proportion of pediatric pandemic A/H1N1/2009 influenza cases who showed seroconversion, the magnitude of this seroconversion, or the factors that can affect the antibody ...

WILLIAMS TL, Pirkle JL, Barr JR.. Simultaneous quantification of hemagglutinin and neuraminidase of influenza virus using isotope dilution mass spectrometry. Vaccine. 2011 Dec 22.  Abstract  
submitted by kickingbird at Jan, 5, 2012 from Vaccine. 2011 Dec 22 (via http://www.ncbi.nlm.nih.gov/pubmed/22197963)
Influenza vaccination is the primary method for preventing influenza and its severe complications. Licensed inactivated vaccines for seasonal or pandemic influenza are formulated to contain a preset amount ...

SUGUITAN AL JR, Matsuoka Y, Lau YF, Santos CP, et. The multi-basic cleavage site of the hemagglutinin of the highly pathogenic A/Vietnam/1203/2004 (H5N1) avian influenza virus acts as a virulence factor in a host-specific manner in mammals. J Virol. 2011.  Abstract  
submitted by kickingbird at Jan, 5, 2012 from J Virol. 2011 (via http://www.ncbi.nlm.nih.gov/pubmed/22205751)
Highly pathogenic avian influenza (HPAI) viruses of the H5 and H7 subtypes typically possess multiple basic amino acids around the cleavage site (MBS) of their hemagglutinin (HA) protein, a recognized ...

VAN TT, Miller J, Warshauer DM, Reisdorf E, et al.. Pooling Nasopharyngeal/Throat Swab Specimens to Increase Testing Capacity for Influenza Viruses by PCR. J Clin Microbiol. 2011.  Abstract  
submitted by kickingbird at Jan, 5, 2012 from J Clin Microbiol. 2011 (via http://www.ncbi.nlm.nih.gov/pubmed/22205820)
Real-time PCR methodology can be applied to rapidly and accurately detect influenza viruses. During times of surge testing or enhanced pandemic surveillance, public health laboratories (PHLs) may experience ...

LIU Q, Ma J, Liu H, Qi W, et al.. Emergence of novel reassortant H3N2 swine influenza viruses with the 2009 pandemic H1N1 genes in the United States. Arch Virol. 2011..  Abstract  
submitted by kickingbird at Jan, 5, 2012 from Arch Virol. 2011. (via http://www.ncbi.nlm.nih.gov/pubmed/22198410)
Reassortant H1 swine influenza viruses (SIVs) carrying 2009 pandemic H1N1 virus (pH1N1) genes have been isolated from pigs worldwide. Seven novel reassortant H3N2 SIVs were identified from diseased pigs ...

BANTIA S, Upshaw R, Babu YS. Characterization of the binding affinities of peramivir and oseltamivir carboxylate to the neuraminidase enzyme. Antiviral Res. 2011;91:288-91.  Abstract  
submitted by kickingbird at Jan, 5, 2012 from Antiviral Res. 2011;91:288-91 (via http://www.ncbi.nlm.nih.gov/pubmed/21722670)
With the continued threat of morbidity and mortality from influenza and the development of resistance to influenza antiviral drugs, there is increasing interest in new treatments, such as the investigational ...

LEE SM, Gai WW, Cheung TK, Peiris JS, et al.. Antiviral effect of a selective COX-2 inhibitor on H5N1 infection in vitro. Antiviral Res. 2011;91:330-4..  Abstract  
submitted by kickingbird at Jan, 5, 2012 from Antiviral Res. 2011;91:330-4. (via http://www.ncbi.nlm.nih.gov/pubmed/21798291)
A selective cyclooxygenase-2 (COX-2) inhibitor has been previously shown to suppress the hyper-induced pro-inflammatory responses in H5N1 infected primary human cells. Here, we demonstrate that COX-2 inhibitors ...

Mariya V.SIVAY; Nikita Y.SILKO; Kirill A.SHARSHOV;. The role of wild goose(Anser) populations of Russia and theTibet Plateau in the spread of the avian influenza virus. Chinese Birds.  Abstract  
submitted by kickingbird at Jan, 2, 2012 from Chinese Birds (via http://www.cnki.net)
Wild birds of the orders Anseriformes and Charadriiformes represent a natural reservoir of low pathogenic avian influenza(LPAI) viruses(family Orthomyxoviridae).Wild geese(order Anseriformes)relating to ...

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