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2024-7-17 19:27:20
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Tharakaraman K, Raman R, Stebbins NW, Viswanathan. Antigenically intact hemagglutinin in circulating avian and swine influenza viruses and potential for H3N2 pandemic. Scientific Reports 3, Article number: 1822.  Abstract  
submitted by kickingbird at May, 14, 2013 from Scientific Reports 3, Article number: 1822 (via http://www.nature.com/srep/2013/130510/srep01822/full/srep01)
The 2009 swine-origin H1N1 influenza, though antigenically novel to the population at the time, was antigenically similar to the 1918 H1N1 pandemic influenza, and consequently was considered to be “archived” ...

Cowling BJ, Freeman G, Wong JY, Wu P, Liao Q, Lau. Preliminary inferences on the age-specific seriousness of human disease caused by avian influenza A(H7N9) infections in China, March to April 2013. Euro Surveill. 2013;18(19):pii=20475..  Abstract  
submitted by kickingbird at May, 10, 2013 from Euro Surveill. 2013;18(19):pii=20475. (via http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=2)
Introduction   In recent weeks, increasing numbers of avian influenza A(H7N9) virus infections have been identified in humans in China [1,2]. Laboratory-confirmed cases of influenza A(H7N9) infection ...

CHO KJ, Lee JH, Hong KW, Kim SH, et al.. Insight into structural diversity of influenza virus hemagglutinin. J Gen Virol. 2013.  Abstract  
submitted by kickingbird at May, 5, 2013 from J Gen Virol. 2013 (via http://www.ncbi.nlm.nih.gov/pubmed/23636824)
Influenza virus infects host cells through membrane fusion, a process mediated by the low pH-induced conformational change of the viral surface glycoprotein hemagglutinin (HA). We determined the structures ...

Zhang Y, Zhang Q, Kong H, et al. H5N1 Hybrid Viruses Bearing 2009/H1N1 Virus Genes Transmit in Guinea Pigs by Respiratory Droplet. Science DOI: 10.1126/science.1229455.  Abstract  
submitted by kickingbird at May, 5, 2013 from Science DOI: 10.1126/science.1229455 (via http://www.sciencemag.org/content/early/2013/05/01/science.1)
In the past, avian influenza viruses have crossed species’ barriers to trigger human pandemics by reassorting with mammal-infective viruses in intermediate livestock hosts. H5N1 viruses are able to infect ...

Zhang Q Y, Wang S C, Wu M L, et al. Epidemiological and risk analysis of the H7N9 subtype influenza outbreak in China at its early stage. Chinese Science Bulletin.  Abstract  
submitted by kickingbird at Apr, 30, 2013 from Chinese Science Bulletin (via http://link.springer.com/article/10.1007/s11434-013-5880-5)
Dozens of human cases infected with H7N9 subtype avian influenza virus (AIV) have been confirmed in China since March, 2013. Distribution data of sexes, ages, professions and regions of the cases were ...

ZHANG K, Zhang Z, Yu Z, Li L, et al. Domestic cats and dogs are susceptible to H9N2 Avian Influenza Virus. Virus Res. 2013 Apr 18.  Abstract  
submitted by kickingbird at Apr, 29, 2013 from Virus Res. 2013 Apr 18 (via http://www.ncbi.nlm.nih.gov/pubmed/23603563)
Replication and transmission of avian influenza virus (AIV) in domestic dogs and cats may pose a risk to humans. The susceptibility of cats and dogs to H9N2 influenza virus was evaluated by intranasally ...

MANZ B, Schwemmle M, Brunotte L. Adaptation of avian influenza A virus polymerase in mammals to overcome the host species barrier. J Virol. 2013 Apr 24.  Abstract  
submitted by kickingbird at Apr, 29, 2013 from J Virol. 2013 Apr 24 (via http://www.ncbi.nlm.nih.gov/pubmed/23616660)
Avian influenza A viruses, such as the highly pathogenic avian H5N1 viruses, sporadically enter into the human population but often do not transmit between individuals. In rare cases, however, they establish ...

CZUDAI-MATWICH V, Schnare M, Pinkenburg O. A simple and fast system for cloning influenza A virus gene segments into pHW2000- and pCAGGS-based vectors. Arch Virol. 2013 Apr 25.  Abstract  
submitted by kickingbird at Apr, 29, 2013 from Arch Virol. 2013 Apr 25 (via http://www.ncbi.nlm.nih.gov/pubmed/23615869)
The reverse genetics system for influenza A viruses described by Hoffmann et al. (Virology 267(2):310-317, 2000, Proc Natl Acad Sci USA 97(11):6108-6113, 2000, ArchVirol 146(12):2275-2289, 2001) is one ...

Planz O.. Development of cellular signaling pathway inhibitors as new antivirals against influenza. Antiviral Res. 2013 Apr 16.  Abstract  
submitted by kickingbird at Apr, 29, 2013 from Antiviral Res. 2013 Apr 16 (via http://www.ncbi.nlm.nih.gov/pubmed/23603495)
Influenza virus exploits a number of cellular signaling pathways during the course of its replication, rendering them potential targets for new therapeutic interventions. Several preclinical approaches ...

Daniel A Salmon, etc.,al. Association between Guillain-Barré syndrome and influenza A (H1N1) 2009 monovalent inactivated vaccines in the USA: a meta-analysis. The Lancet, Volume 381, Issue 9876.  Abstract  
submitted by kickingbird at Apr, 28, 2013 from The Lancet, Volume 381, Issue 9876 (via http://www.thelancet.com/journals/lancet/article/PIIS0140-67)
Background The influenza A (H1N1) 2009 monovalent vaccination programme was the largest mass vaccination initiative in recent US history. Commensurate with the size and scope of the vaccination programme, ...

Corman VM, Eickmann M, Landt O, Bleicker T, Brünin. Specific detection by real-time reverse-transcription PCR assays of a novel avian influenza A(H7N9) strain associated with human spillover infections in China. Euro Surveill. 2013;18(16):pii=20461.  Full Text  
submitted by kickingbird at Apr, 26, 2013 from Euro Surveill. 2013;18(16):pii=20461 (via http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=2)
Background An avian influenza A(H7N9) virus has emerged in south eastern China in March 2013 [1]. As of 16 April 2013, the Chinese authorities have reported 63 laboratory-confirmed human cases, 14 of ...

Li Q, Zhou L, Zhou M, etc., al.. Preliminary Report: Epidemiology of the Avian Influenza A (H7N9) Outbreak in China. N Engl J Med 2013 Apr 24.  Abstract  
submitted by kickingbird at Apr, 26, 2013 from N Engl J Med 2013 Apr 24 (via http://www.nejm.org/doi/full/10.1056/NEJMoa1304617#Top)
Background The first identified cases of avian influenza A (H7N9) virus infection in humans occurred in China during February and March 2013. We analyzed data obtained from field investigations to characterize ...

Y Chen, etc.,al. Human infections with the emerging avian influenza A H7N9 virus from wet market poultry: clinical analysis and characterisation of viral genome. The Lancet,25 April 2013.  Abstract  
submitted by kickingbird at Apr, 26, 2013 from The Lancet,25 April 2013 (via http://www.lancet.com/journals/lancet/article/PIIS0140-6736()
Background Human infection with avian influenza A H7N9 virus emerged in eastern China in February, 2013, and has been associated with exposure to poultry. We report the clinical and microbiological ...

ZHANG Y, Wang N, Cao J, Chen H, et al. Genetic characterization of H1N2 swine influenza virus isolated in China and its pathogenesis and inflammatory responses in mice.. Arch Virol. 2013.  Abstract  
submitted by kickingbird at Apr, 21, 2013 from Arch Virol. 2013 (via http://www.ncbi.nlm.nih.gov/pubmed/23591972)
In 2009, two H1N2 influenza viruses were isolated from trachea swabs of pigs in Hubei in China. We compared these sequences with the other 18 complete genome sequences of swine H1N2 isolates from China ...

HUI DS, Lee N, Chan PK. Adjunctive therapies and immunomodulatory agents in the management of severe influenza. Antiviral Res. 2013 Apr 8. pii: S0166-3542(13)0008.  Abstract  
submitted by kickingbird at Apr, 21, 2013 from Antiviral Res. 2013 Apr 8. pii: S0166-3542(13)0008 (via http://www.ncbi.nlm.nih.gov/pubmed/23578727)
In addition to neuraminidase inhibitors and other drugs that directly target viral replication, a number of adjunctive and immunomodulatory therapies are currently under evaluation for the treatment of ...

LAURSEN NS, Wilson IA. Broadly neutralizing antibodies against influenza viruses. Antiviral Res. 2013 Apr 9. pii: S0166-3542(13)0008.  Abstract  
submitted by kickingbird at Apr, 21, 2013 from Antiviral Res. 2013 Apr 9. pii: S0166-3542(13)0008 (via http://www.ncbi.nlm.nih.gov/pubmed/23583287)
Despite available antivirals and vaccines, influenza continues to be a major cause of mortality worldwide. Vaccination generally induces an effective, but strain-specific antibody response. As the virus ...

Jonges M, Meijer A, Fouchier RA, Koch G, Li J, Pan. Guiding outbreak management by the use of influenza A(H7Nx) virus sequence analysis. Euro Surveill. 2013;18(16):pii=20460..  Full Text  
submitted by kickingbird at Apr, 20, 2013 from Euro Surveill. 2013;18(16):pii=20460. (via http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=2)
The recently identified human infections with avian influenza A(H7N9) viruses in China raise important questions regarding possible source and risk to humans. Sequence comparison with an influenza A(H7N7) ...

TAFESSE FG, Sanyal S, Ashour J, Guimaraes CP, et a. Intact sphingomyelin biosynthetic pathway is essential for intracellular transport of influenza virus glycoproteins.. Proc Natl Acad Sci U S A. 2013 Apr 1.  Abstract  
submitted by kickingbird at Apr, 14, 2013 from Proc Natl Acad Sci U S A. 2013 Apr 1 (via http://www.ncbi.nlm.nih.gov/pubmed/23576732)
Cells genetically deficient in sphingomyelin synthase-1 (SGMS1) or blocked in their synthesis pharmacologically through exposure to a serine palmitoyltransferase inhibitor (myriocin) show strongly reduced ...

Baz M, Paskel M, Matsuoka Y, Zengel J, Cheng X, Ji. Replication and immunogenicity of swine, equine and avian H3 subtype influenza viruses in mice and ferrets. J Virol. 2013 Apr 10..  Abstract  
submitted by kickingbird at Apr, 14, 2013 from J Virol. 2013 Apr 10. (via http://www.ncbi.nlm.nih.gov/pubmed/23576512)
Since it is difficult to predict which influenza virus subtype will cause an influenza pandemic, it is important to prepare influenza virus vaccines against different subtypes and evaluate the safety and ...

RB Gao, B Cao,YW Hu, ZJ Feng, DY Wang, etc.,al. Human Infection with a Novel Avian-Origin Influenza A (H7N9) Virus. April 11, 2013DOI: 10.1056/NEJMoa1304459.  Abstract  
submitted by kickingbird at Apr, 12, 2013 from April 11, 2013DOI: 10.1056/NEJMoa1304459 (via http://www.nejm.org/doi/full/10.1056/NEJMoa1304459?query=fea)
Background Infection of poultry with influenza A subtype H7 viruses occurs worldwide, but the introduction of this subtype to humans in Asia has not been observed previously. In March 2013, three urban ...

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