WESTGEEST KB, de Graaf M, Fourment M, Bestebroer T. Genetic Evolution of Neuraminidase of Influenza A (H3N2) Viruses from 1968 to 2009 and its Correspondence to Hemagglutinin. J Gen Virol. 2012. Abstract
submitted by kickingbird at Jun, 25, 2012 from J Gen Virol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22718569)
Each year, influenza viruses cause epidemics by evading preexisting humoral immunity through mutations in the major glycoproteins: the hemagglutinin (HA) and the neuraminidase (NA). In 2004, Smith et al. ... CROVILLE G, Soubies SM, Barbieri J, Klopp C, et al. Field Monitoring of Avian Influenza Viruses: Whole Genome Sequencing and Tracking of Neuraminidase Evolution Using 454 Pyrosequencing. J Clin Microbiol. 2012. Abstract
submitted by kickingbird at Jun, 25, 2012 from J Clin Microbiol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22718944)
Adaptation of avian influenza viruses (AIVs) from waterfowl to domestic poultry with a deletion in the neuraminidase (NA) stalk has already been reported. The way the virus undergoes this evolution is ... PANTIN-JACKWOOD MJ, Smith DM, Wasilenko JL, Cagle. Effect of age on the pathogenesis and innate immune responses in Pekin ducks infected with different H5N1 highly pathogenic avian influenza viruses. Virus Res. 2012. Abstract
submitted by kickingbird at May, 29, 2012 from Virus Res. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22595263)
The pathogenicity of H5N1 highly pathogenic avian influenza (HPAI) viruses in domestic ducks varies between different viruses and is affected by the age of the ducks, with younger ducks presenting a more ... STARICK E, Lange E, Grund C, Grosse Beilage E, et. Reassortants of pandemic influenza A virus H1N1/2009 and endemic porcine HxN2 viruses emerge in swine populations in Germany. J Gen Virol. 2012. Abstract
submitted by kickingbird at May, 29, 2012 from J Gen Virol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22622326)
The incursion of the human pandemic influenza A virus H1N1 (2009) (H1N1 pdm) into pig populations and its on-going co-circulation with endemic swine influenza viruses (SIV) has yielded distinct human-porcine ... KASSON PM. Receptor Binding by Influenza Virus: Using Computational Techniques to Extend Structural Data. Biochemistry. 2012. Abstract
submitted by kickingbird at May, 25, 2012 from Biochemistry. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22409249)
Influenza attaches to host cells via hemagglutinin binding of cell-surface glycans. These relatively low-affinity interactions involving flexible ligands are critical in determining tissue and host specificity, ... ZHOU JP, Ge FF, Liu J, Ju HB, et al. Epidemiological survey and genetic evolution of H9 subtype influenza viruses in Shanghai, China, from 2006 to 2010. Arch Virol. 2012. Abstract
submitted by kickingbird at May, 25, 2012 from Arch Virol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22407404)
The H9N2 influenza virus is endemic in poultry. We report its occurrence in live-poultry markets, fair-trade markets and poultry farms in the Shanghai region between September 2006 and December 2010. An ... MOON HJ, Lee JS, Choi YK, Park JY, et al. Induction of type I interferon by high-molecular poly-gamma-glutamate protects B6.A2G-Mx1 mice against influenza A virus. Antiviral Res. 2012. Abstract
submitted by kickingbird at May, 25, 2012 from Antiviral Res. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22401806)
In addition to development of vaccines and synthetic antiviral drugs, recent studies have advocated the use of natural substances that inhibit or prevent viral infections. High-molecular-weight poly-γ-glutamate ... HELDT FS, Frensing T, Reichl U. Modeling the intracellular dynamics of influenza virus replication to understand the control of viral RNA synthesis. J Virol. 2012.. Abstract
submitted by kickingbird at May, 25, 2012 from J Virol. 2012. (via http://www.ncbi.nlm.nih.gov/pubmed/22593159)
Influenza viruses transcribe and replicate their negative-sense RNA genome inside the nucleus of host cells via three viral RNA species. In the course of an infection, these RNAs show distinct dynamics ... VAN BORM S, Rosseel T, Vangeluwe D, Vandenbussche. Phylogeographic analysis of avian influenza viruses isolated from Charadriiformes in Belgium confirms intercontinental reassortment in gulls. Arch Virol. 2012.. Abstract
submitted by kickingbird at May, 25, 2012 from Arch Virol. 2012. (via http://www.ncbi.nlm.nih.gov/pubmed/22580556)
Nine influenza viruses isolated from gulls and shorebirds in Belgium (2008-2010), including H3N8, H5N2, H6N1, H11N9, H13N6, H13N8, and H16N3 subtypes, were targeted using random amplification and next-generation ... Chou YY, Vafabakhsh R, Doganay S, Gao Q, et al. One influenza virus particle packages eight unique viral RNAs as shown by FISH. Proc Natl Acad Sci U S A. 2012. Abstract
submitted by kickingbird at May, 8, 2012 from Proc Natl Acad Sci U S A. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22547828)
Influenza A virus possesses a segmented genome of eight negative-sense, single-stranded RNAs. The eight segments have been shown to be represented in approximately equal molar ratios in a virus population; ... Zhou F, Zhou J, Ma L, Song S, et al. High-yield production of a stable Vero cell-based vaccine candidate against the highly pathogenic avian influenza virus H5N1.. Biochem Biophys Res Commun. 2012.. Abstract
submitted by kickingbird at May, 8, 2012 from Biochem Biophys Res Commun. 2012. (via http://www.ncbi.nlm.nih.gov/pubmed/22554519)
Highly pathogenic avian influenza (HPAI) viruses pose a global pandemic threat, for which rapid large-scale vaccine production technology is critical for prevention and control. Because chickens are highly ... Hui-Ling Yen, Joseph Sriyal Malik Peiris. Virology: Bird flu in mammals. Nature 2012 doi:10.1038/nature11192. Abstract
submitted by kickingbird at May, 3, 2012 from Nature 2012 doi:10.1038/nature11192 (via http://www.nature.com/nature/journal/vaop/ncurrent/full/natu)
An engineered influenza virus based on a haemagglutinin protein from H5N1 avian influenza, with just four mutations, can be transmitted between ferrets, emphasizing the potential for a human pandemic to ... Masaki Imai, etc.,al. Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets. Nature 2012 doi:10.1038/nature10831. Full Text
submitted by kickingbird at May, 3, 2012 from Nature 2012 doi:10.1038/nature10831 (via http://www.nature.com/nature/journal/vaop/ncurrent/full/natu)
Highly pathogenic avian H5N1 influenza A viruses occasionally infect humans, but currently do not transmit efficiently among humans. The viral haemagglutinin (HA) protein is a known host-range determinant ... Hongjie Yu, Simon Cauchemez, Christl A. Donnelly. Transmission Dynamics, Border Entry Screening, and School Holidays during the 2009 Influenza A (H1N1) Pandemic, China. Apr 18 Emerg Infect Dis. Abstract
submitted by kickingbird at Apr, 22, 2012 from Apr 18 Emerg Infect Dis (via http://wwwnc.cdc.gov/eid/article/18/5/11-0356_article.htm)
Pandemic influenza A (H1N1) 2009 virus spread rapidly around the world in 2009. We used multiple data sources from surveillance systems and specific investigations to characterize the transmission patterns ... NORONHA JM, Liu M, Squires RB, Pickett BE, et al. Influenza Sequence Feature Variant Type (Flu-SFVT) analysis: evidence for a role of NS1 in influenza host range restriction. J Virol. 2012 Mar 7.. Abstract
submitted by kickingbird at Mar, 14, 2012 from J Virol. 2012 Mar 7. (via http://www.ncbi.nlm.nih.gov/pubmed/22398283)
Genetic drift of influenza virus genomic sequences occurs through the combined effects of sequence alterations introduced by a low fidelity polymerase and the varying selective pressures experienced as ... MAAMARY J, Pica N, Belicha-Villanueva A, Chou YY,. Attenuated influenza virus construct with enhanced hemagglutinin protein expression. J Virol. 2012. Abstract
submitted by kickingbird at Mar, 14, 2012 from J Virol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22398291)
Influenza A viruses encoding an altered viral NS1 protein have emerged as promising live attenuated vaccine platforms. A carboxy-terminal truncation in the NS1 protein compromises its interferon antagonism ... Belser JA, Gustin KM, Maines TR, Pantin-Jackwood M. Influenza Virus Respiratory Infection and Transmission Following Ocular Inoculation in Ferrets. PLoS Pathog 8(3): e1002569. doi:10.1371/journal.p. Abstract
submitted by kickingbird at Mar, 3, 2012 from PLoS Pathog 8(3): e1002569. doi:10.1371/journal.p (via http://www.plospathogens.org/article/info%3Adoi%2F10.1371%2F)
While influenza viruses are a common respiratory pathogen, sporadic reports of conjunctivitis following human infection demonstrates the ability of this virus to cause disease outside of the respiratory ... S. Tong,etc.,al. A distinct lineage of influenza A virus from bats. PNAS February 27, 2012. Abstract
submitted by kickingbird at Feb, 29, 2012 from PNAS February 27, 2012 (via http://www.pnas.org/content/early/2012/02/17/1116200109.abst)
Influenza A virus reservoirs in animals have provided novel genetic elements leading to the emergence of global pandemics in humans. Most influenza A viruses circulate in waterfowl, but those that infect ... MACDONALD LA, Aggarwal S, Bussey KA, Desmet EA, et. Molecular interactions and trafficking of influenza A virus polymerase proteins analyzed by specific monoclonal antibodies. Virology. 2012. Abstract
submitted by kickingbird at Feb, 19, 2012 from Virology. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22325937)
The influenza polymerase complex composed of PA, PB1 and PB2, plays a key role in viral replication and pathogenicity. Newly synthesized components must be translocated to the nucleus, where replication ... J Gen Virol. 2012. An influenza reassortant with polymerase of pH1N1 and NS gene of H3N2 influenza A virus is attenuated in vivo. SHELTON H, Smith M, Hartgroves LC, Stilwell P, et. Abstract
submitted by kickingbird at Feb, 19, 2012 from SHELTON H, Smith M, Hartgroves LC, Stilwell P, et (via http://www.ncbi.nlm.nih.gov/pubmed/22323532)
Influenza viruses readily mutate by accumulating point mutations and also by reassortment in which they acquire whole gene segments from another virus in a co-infected host. The NS1 gene is a major virulence ... 5146 items, 20/Page, Page[197/258][|<<] [|<] [191] [192] [193] [194] [195] [196] [197] [198] [199] [200] [>|] [>>|] |
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