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2024-4-20 16:23:50
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SIMULUNDU E, Nao N, Yabe J, Muto NA, et al. The zoonotic potential of avian influenza viruses isolated from wild waterfowl in Zambia. Arch Virol. 2014.  Abstract  
submitted by kickingbird at Jun, 16, 2014 from Arch Virol. 2014 (via http://www.ncbi.nlm.nih.gov/pubmed/24862188)
Whilst remarkable progress in elucidating the mechanisms governing interspecies transmission and pathogenicity of highly pathogenic avian influenza viruses (AIVs) has been made, similar studies focusing ...

PAN Y, Sasaki T, Kubota-Koketsu R, Inoue Y, et al. Human monoclonal antibodies derived from a patient infected with 2009 pandemic influenza A virus broadly cross-neutralize group 1 influenza viruses. Biochem Biophys Res Commun. 2014 May 22. pii: S000.  Abstract  
submitted by kickingbird at Jun, 16, 2014 from Biochem Biophys Res Commun. 2014 May 22. pii: S000 (via http://www.ncbi.nlm.nih.gov/pubmed/24858683)
Influenza viruses are a continuous threat to human public health because of their ability to evolve rapidly through genetic drift and reassortment. Three human monoclonal antibodies (HuMAbs) were generated ...

SASAKI Y, Kakisaka M, Chutiwitoonchai N, Tajima S,. Identification of a novel multiple kinase inhibitor with potent antiviral activity against influenza virus by reducing viral polymerase activity. Biochem Biophys Res Commun. 2014 May 22. pii: S000.  Abstract  
submitted by kickingbird at Jun, 16, 2014 from Biochem Biophys Res Commun. 2014 May 22. pii: S000 (via http://www.ncbi.nlm.nih.gov/pubmed/24858693)
Neuraminidase inhibitors are the only currently available influenza treatment, although resistant viruses to these drugs have already been reported. Thus, new antiviral drugs with novel mechanisms of action ...

ZHANG Y, Whittaker GR. Influenza entry pathways in polarized MDCK cells. Biochem Biophys Res Commun. 2014 May 27. pii: S000.  Abstract  
submitted by kickingbird at Jun, 16, 2014 from Biochem Biophys Res Commun. 2014 May 27. pii: S000 (via http://www.ncbi.nlm.nih.gov/pubmed/24878525)
In non-polarized cell culture models, influenza virus has been shown to enter host cells via multiple endocytic pathways, including classical clathrin-mediated endocytic routes (CME), clathrin- and caveolae-independent ...

LEUNG YH, Nicholls JM, Ho CK, Sia SF, et al. Highly pathogenic avian influenza A H5N1 and pandemic H1N1 virus infections have different phenotypes in Toll-like Receptor (TLR) 3 knock-out mice. J Gen Virol. 2014 May 30. pii: vir.0.066258-0. doi.  Abstract  
submitted by kickingbird at Jun, 16, 2014 from J Gen Virol. 2014 May 30. pii: vir.0.066258-0. doi (via http://www.ncbi.nlm.nih.gov/pubmed/24878639)
Toll-like receptors (TLR) play an important role in innate immunity to virus infections. We investigated the role of TLR3 in the pathogenesis of H5N1 and pandemic H1N1 (pH1N1) influenza virus infection ...

LUPFER C, Thomas PG, Kanneganti TD. NOD2 dependent DC activation is necessary for innate immunity and optimal CD8+ T cell responses to influenza A virus infection. J Virol. 2014 May 28. pii: JVI.01110..  Abstract  
submitted by kickingbird at Jun, 16, 2014 from J Virol. 2014 May 28. pii: JVI.01110. (via http://www.ncbi.nlm.nih.gov/pubmed/24872587)
Abstract Nucleotide oligomerization and binding domain (NOD) like-receptors (NLRs) have demonstrated importance in the innate immune response to viral infection. Recent findings have implicated NLRP3, ...

COBBIN JC, Ong C, Verity E, Gilbertson BP, et al. Influenza Virus PB1 and NA Gene Segments can Co-segregate during Vaccine Reassortment Driven by Interactions in the PB1 Coding Region. J Virol. 2014 May 28. pii: JVI.01022.  Abstract  
submitted by kickingbird at Jun, 16, 2014 from J Virol. 2014 May 28. pii: JVI.01022 (via http://www.ncbi.nlm.nih.gov/pubmed/24872588)
Abstract Egg-grown influenza vaccine yields are maximised by infection with a seed virus produced by "classical reassortment" of a seasonal isolate with a highly egg-adapted strain. Seed viruses are ...

KANG X, Wu W, Zhang C, Liu L, et al. Detection of Avian influenza A/H7N9/2013 virus by Real-Time Reverse Transcription-Polymerase Chain Reaction. J Virol Methods. 2014 May 28. pii: S0166-0934(14)0.  Abstract  
submitted by kickingbird at Jun, 16, 2014 from J Virol Methods. 2014 May 28. pii: S0166-0934(14)0 (via http://www.ncbi.nlm.nih.gov/pubmed/24880072)
The first case of avian influenza A/H7N9 infection was reported in Shanghai in mid-February 2013; by May 1, 2013, it had infected 127 people and caused 26 deaths in 10 provinces in China. Therefore, it ...

XU L, Bao L, Deng W, Zhu H, et al. Rapid adaptation of avian H7N9 virus in pigs. Virology. 2014;452-453:231-6.  Abstract  
submitted by kickingbird at Jun, 16, 2014 from Virology. 2014;452-453:231-6 (via http://www.ncbi.nlm.nih.gov/pubmed/24606700)
How the H7N9 avian influenza virus gained the distinct ability to infect humans is unclear. Pigs are an important host in influenza virus ecology because they are susceptible to infection with both avian ...

ZHANG Y, Mao H, Yan J, Zhang L, et al. Isolation and characterization of H7N9 avian influenza A virus from humans with respiratory diseases in Zhejiang, China. Virus Res. 2014 May 24. pii: S0168-1702(14)00183.  Abstract  
submitted by kickingbird at Jun, 16, 2014 from Virus Res. 2014 May 24. pii: S0168-1702(14)00183 (via http://www.ncbi.nlm.nih.gov/pubmed/24867615)
In 2013, the novel reassortant avian-origin influenza A (H7N9) virus was reported in China. Through enhanced surveillance, infection by the H7N9 virus in humans was first identified in Zhejiang Province. ...

Wang L, Cowling BJ, Wu P, Yu J, Li F, Zeng L, et a. Human Exposure to Live Poultry and Psychological and Behavioral Responses to Influenza A(H7N9), China. Emerg Infect Dis. 2014 Aug.  Abstract  
submitted by kickingbird at Jun, 5, 2014 from Emerg Infect Dis. 2014 Aug (via http://wwwnc.cdc.gov/eid/article/20/8/13-1821_article.htm)
To investigate human exposure to live poultry and changes in risk perception and behavior after the April 2013 influenza A(H7N9) outbreak in China, we surveyed 2,504 urban residents in 5 cities and 1,227 ...

SG. Vachieri, etc.,al. Receptor binding by H10 influenza viruses. Nature (2014) doi:10.1038/nature13443.  Abstract  
submitted by kickingbird at May, 30, 2014 from Nature (2014) doi:10.1038/nature13443 (via http://www.nature.com/nature/journal/vaop/ncurrent/full/natu)
H10N8 follows H7N9 and H5N1 as the latest in a line of avian influenza viruses that cause serious disease in humans and have become a threat to public health1. Since December 2013, three human cases of ...

NELSON EA, Ip M, Tam JS, Mounts AW, et al. Burden of influenza infection in hospitalised children below 6 months of age and above in Hong Kong from 2005 to 2011. Vaccine. 2014 May 13. pii: S0264-410X(14)00601.  Abstract  
submitted by kickingbird at May, 27, 2014 from Vaccine. 2014 May 13. pii: S0264-410X(14)00601 (via http://www.ncbi.nlm.nih.gov/pubmed/24837762)
The World Health Organization recommends vaccination of pregnant women for seasonal influenza that can also protect infants aged below 6 months. We estimated incidence and disease burden of influenza in ...

BYRD-LEOTIS L, Liu R, Bradley KC, Lasanajak Y, et. Shotgun glycomics of pig lung identifies natural endogenous receptors for influenza viruses. Proc Natl Acad Sci U S A. 2014 May 19..  Abstract  
submitted by kickingbird at May, 27, 2014 from Proc Natl Acad Sci U S A. 2014 May 19. (via http://www.ncbi.nlm.nih.gov/pubmed/24843157)
Influenza viruses bind to host cell surface glycans containing terminal sialic acids, but as studies on influenza binding become more sophisticated, it is becoming evident that although sialic acid may ...

LIN Z, Xu C, Liu B, Ji Y, et al. Analysis of the phylogeny of Chinese H9N2 avian influenza viruses and their pathogenicity in mice. Arch Virol. 2014 May 17..  Abstract  
submitted by kickingbird at May, 27, 2014 from Arch Virol. 2014 May 17. (via http://www.ncbi.nlm.nih.gov/pubmed/24838853)
We isolated nineteen strains of H9N2 influenza virus from farms across five northern Chinese provinces between 2001 and 2012. Sequence analysis of the genes for the two surface glycoproteins revealed that ...

POMORSKA-MOL M, Markowska-Daniel I, Kwit K, Czyzew. Immune and inflammatory response in pigs during acute influenza caused by H1N1 swine influenza virus. Arch Virol. 2014 May 21.  Abstract  
submitted by kickingbird at May, 27, 2014 from Arch Virol. 2014 May 21 (via http://www.ncbi.nlm.nih.gov/pubmed/24846450)
Swine influenza (SI) is an acute respiratory disease of pigs, caused by swine influenza virus (SIV). Little is known about the inflammatory response in the lung during acute SI and its correlation with ...

JULANDER JG, Kesler K, Van Wettere AJ, Morrey JD,. The use of plethysmography in determining the severity of lung pathology in a mouse model of minimally lethal influenza virus infection. Antiviral Res. 2014 May 14..  Abstract  
submitted by kickingbird at May, 27, 2014 from Antiviral Res. 2014 May 14. (via http://www.ncbi.nlm.nih.gov/pubmed/24837607)
To characterize the impact on lung function, we assessed plethysmography parameters in a course of infection with mouse-adapted A/Pennsylvania/14/2010 (H3N2) influenza virus. Several parameters, represented ...

ESCURET V, Collins PJ, Casalegno JS, Vachieri SG,. A novel I221 L substitution in neuraminidase confers high level resistance to oseltamivir in influenza B viruses. J Infect Dis. 2014..  Abstract  
submitted by kickingbird at May, 13, 2014 from J Infect Dis. 2014. (via http://www.ncbi.nlm.nih.gov/pubmed/24795482)
Introduction.?Influenza B viruses with a novel I221 L substitution in neuraminidase (NA) conferring high level resistance to oseltamivir were isolated from an immunocompromised patient after prolonged ...

Freidl GS, Meijer A, de Bruin E, de Nardi M, Munoz. Influenza at the animal–human interface: a review of the literature for virological evidence of human infection with swine or avian influenza viruses other than A(H5N1). Euro Surveill. 2014;19(18):pii=20793..  Abstract  
submitted by kickingbird at May, 13, 2014 from Euro Surveill. 2014;19(18):pii=20793. (via http://eurosurveillance.org/ViewArticle.aspx?ArticleId=20793)
Factors that trigger human infection with animal influenza virus progressing into a pandemic are poorly understood. Within a project developing an evidence-based risk assessment framework for influenza ...

Francesca Diane M. Liu, etc.,al. Timed Action of IL-27 Protects from Immunopathology while Preserving Defense in Influenza. PLOS Pathogens.  Abstract  
submitted by kickingbird at May, 12, 2014 from PLOS Pathogens (via http://www.plospathogens.org/article/info%3Adoi%2F10.1371%2F)
Infection with influenza virus can result in massive pulmonary infiltration and potentially fatal immunopathology. Understanding the endogenous mechanisms that control immunopathology could provide a key ...

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