Yan LM, etc.,al. Combined use of live-attenuated and inactivated influenza vaccines to enhance heterosubtypic protection. Virology. 2018 Sep 21;525:73-82. Abstract
submitted by kickingbird at Sep, 28, 2018 from Virology. 2018 Sep 21;525:73-82 (via https://www.ncbi.nlm.nih.gov/pubmed/30248524)
The limited protection of current commerical vaccines necessitates the investigation of novel vaccine strategies for unpredictable outbreaks. To investigate the feasibility of using vaccines derived from ... Ferraris O, etc.,al. The NS Segment of H1N1pdm09 Enhances H5N1 Pathogenicity in a Mouse Model of Influenza Virus Infections. Viruses. 2018 Sep 17. Abstract
submitted by kickingbird at Sep, 26, 2018 from Viruses. 2018 Sep 17 (via https://www.ncbi.nlm.nih.gov/pubmed/30227598)
In 2009, the co-circulation of H5N1 and H1N1pdm09 raised concerns that a reassortment event may lead to highly pathogenic influenza strains. H1N1pdm09 and H5N1 are able to infect the same target cells ... Pereira CF, etc.,al. Effects of mutations in the effector domain of influenza A virus NS1 protein. BMC Res Notes. 2018 Sep 18. Abstract
submitted by kickingbird at Sep, 26, 2018 from BMC Res Notes. 2018 Sep 18 (via https://www.ncbi.nlm.nih.gov/pubmed/30227889)
OBJECTIVE: The multifunctional NS1 protein of influenza A virus has roles in antagonising cellular innate immune responses and promoting viral gene expression. To better understand the interplay between ... Tan M, etc.,al. Saliva as a source of reagent to study human susceptibility to avian influenza H7N9 virus infection. Emerg Microbes Infect. 2018 Sep 19. Abstract
submitted by kickingbird at Sep, 26, 2018 from Emerg Microbes Infect. 2018 Sep 19 (via https://www.ncbi.nlm.nih.gov/pubmed/30228261)
Avian influenza H7N9 viruses are an important public health concern due to their high mortality rate and potentials for future pandemics. We investigated human susceptibility to H7N9 viruses using recombinant ... Thompson CP, etc.,al. A naturally protective epitope of limited variability as an influenza vaccine target. Nat Commun. 2018 Sep 21;9(1):3859. Abstract
submitted by kickingbird at Sep, 26, 2018 from Nat Commun. 2018 Sep 21;9(1):3859 (via https://www.ncbi.nlm.nih.gov/pubmed/30242149)
Current antigenic targets for influenza vaccine development are either highly immunogenic epitopes of high variability or conserved epitopes of low immunogenicity. This requires continuous update of the ... Lee DH, Torchetti MK, Hicks J, Killian ML, Bahl J,. Transmission Dynamics of Highly Pathogenic Avian Influenza Virus A(H5Nx) Clade 2.3.4.4, North America, 2014~2015. Emerg Infect Dis. 2018 Oct;24(10):1840-1848.. Abstract
submitted by kickingbird at Sep, 26, 2018 from Emerg Infect Dis. 2018 Oct;24(10):1840-1848. (via https://www.ncbi.nlm.nih.gov/pubmed/30226167)
Eurasia highly pathogenic avian influenza virus (HPAIV) H5 clade 2.3.4.4 emerged in North America at the end of 2014 and caused outbreaks affecting >50 million poultry in the United States before eradication ... Diallo A, etc.,al. Immunogenicity and safety of MF59-adjuvanted and full-dose unadjuvanted trivalent inactivated influenza vaccines among vaccine-na?ve children in a randomized clinical trial in rural Senegal. Vaccine. 2018 Sep 14.. Abstract
submitted by kickingbird at Sep, 26, 2018 from Vaccine. 2018 Sep 14. (via https://www.ncbi.nlm.nih.gov/pubmed/30224199)
INTRODUCTION: Effective, programmatically suitable influenza vaccines are needed for low-resource countries.MATERIALS AND METHODS: This phase II, placebo-controlled, randomized safety and immunogenicity ... Berg J, etc.,al. Optimization of cell-laden bioinks for 3D bioprinting and efficient infection with influenza A virus. Sci Rep. 2018 Sep 17;8(1):13877.. Abstract
submitted by kickingbird at Sep, 26, 2018 from Sci Rep. 2018 Sep 17;8(1):13877. (via https://www.ncbi.nlm.nih.gov/pubmed/30224659)
Bioprinting is a new technology, which arranges cells with high spatial resolution, but its potential to create models for viral infection studies has not yet been fully realized. The present study describes ... Te Velthuis AJW, etc.,al. Mini viral RNAs act as innate immune agonists during influenza virus infection. Nat Microbiol. 2018 Sep 17.. Abstract
submitted by kickingbird at Sep, 26, 2018 from Nat Microbiol. 2018 Sep 17. (via https://www.ncbi.nlm.nih.gov/pubmed/30224800)
The molecular processes that determine the outcome of influenza virus infection in humans are multifactorial and involve a complex interplay between host, viral and bacterial factors1. However, it is generally ... Sunwoo SY, etc.,al. A Universal Influenza Virus Vaccine Candidate Tested in a Pig Vaccination-Infection Model in the Presence of Maternal Antibodies. Vaccines (Basel). 2018 Sep 14;6(3). Abstract
submitted by kickingbird at Sep, 26, 2018 from Vaccines (Basel). 2018 Sep 14;6(3) (via https://www.ncbi.nlm.nih.gov/pubmed/30223475)
The antigenically conserved hemagglutinin stalk region is a target for universal influenza virus vaccines since antibodies against it can provide broad protection against influenza viruses of different ... Li L, DeLiberto TJ, Killian ML, Torchetti MK, et a. Evolutionary pathway for the 2017 emergence of a novel highly pathogenic avian influenza A(H7N9) virus among domestic poultry in Tennessee, United States. Virology. 2018 Sep 17. Abstract
submitted by kickingbird at Sep, 24, 2018 from Virology. 2018 Sep 17 (via https://www.ncbi.nlm.nih.gov/m/pubmed/30236990/)
In March 2017, a novel highly pathogenic avian influenza A(H7N9) virus was detected at two commercial broiler breeder facilities in Tennessee, United States. In this study, a wild bird low pathogenic avian ... DeDiego ML, Chiem K, Topham DJ.. Directed selection of amino acid changes in the influenza hemagglutinin and neuraminidase affecting protein antigenicity. Vaccine. 2018 Sep 14.. Abstract
submitted by kickingbird at Sep, 24, 2018 from Vaccine. 2018 Sep 14. (via https://www.ncbi.nlm.nih.gov/m/pubmed/30224200/)
Influenza virus hemagglutinin (HA) and neuraminidase (NA) proteins elicit protective antibody responses and therefore, are used as targets for vaccination, especially the HA protein. However, these proteins ... Benton DJ, Nans A, Calder LJ, Turner J, et al. Influenza hemagglutinin membrane anchor. Proc Natl Acad Sci U S A. 2018 Sep 17. Abstract
submitted by kickingbird at Sep, 24, 2018 from Proc Natl Acad Sci U S A. 2018 Sep 17 (via https://www.ncbi.nlm.nih.gov/m/pubmed/30224494/)
Viruses with membranes fuse them with cellular membranes, to transfer their genomes into cells at the beginning of infection. For Influenza virus, the membrane glycoprotein involved in fusion is the hemagglutinin ... Gonzalez AJ, Ijezie EC, Balemba OB, Miura TA, et a. Attenuation of influenza A virus disease severity by viral co-infection in a mouse model. J Virol. 2018 Sep 19.. Abstract
submitted by kickingbird at Sep, 24, 2018 from J Virol. 2018 Sep 19. (via https://www.ncbi.nlm.nih.gov/m/pubmed/30232180/)
Influenza viruses and rhinoviruses are responsible for a large number of acute respiratory viral infections in human populations and are detected as co-pathogens within hosts. Clinical and epidemiological ... Scheller N, et al.. Pro-viral miRNAs detected in BALF extracellular vesicles of patients with influenza virus-induced ARDS. J Infect Dis. 2018 Sep 15. Abstract
submitted by kickingbird at Sep, 24, 2018 from J Infect Dis. 2018 Sep 15 (via https://www.ncbi.nlm.nih.gov/m/pubmed/30239899/)
Influenza A virus (IAV) causes severe respiratory infections and alveolar epithelial damage resulting in acute respiratory distress syndrome (ARDS). Extracellular vesicles (EV) have been shown to mediate ... Santner P, Martins JMDS, Kampmeyer C, Hartmann-Pet. Random mutagenesis analysis of the Influenza A M2 proton channel reveals novel resistance mutants. Biochemistry 2018 Sep 19.. Abstract
submitted by kickingbird at Sep, 24, 2018 from Biochemistry 2018 Sep 19. (via https://www.ncbi.nlm.nih.gov/m/pubmed/30230310/)
The influenza M2 proton channel is a major drug target, but unfortunately, the acquisition of resistance mutations greatly reduces the functional life-span of a drug in influenza treatment. New M2 inhibitors ... Louisa E. Sjaastad, Elizabeth J. Fay, Jessica K. F. Distinct antiviral signatures revealed by the magnitude and round of influenza virus replication in vivo. PNAS September 18, 2018 115 (38) 9610-9615. Abstract
submitted by kickingbird at Sep, 20, 2018 from PNAS September 18, 2018 115 (38) 9610-9615 (via http://www.pnas.org/content/115/38/9610)
Influenza virus has a broad cellular tropism in the respiratory tract. Infected epithelial cells sense the infection and initiate an antiviral response. To define the antiviral response at the earliest ... Astill J, etc.,al. A Comparison of Toll-Like Receptor 5 and 21 Ligands as Adjuvants for a Formaldehyde Inactivated H9N2 Avian Influenza Virus Vaccine in Chickens. Viral Immunol. 2018 Sep 15.. Abstract
submitted by kickingbird at Sep, 20, 2018 from Viral Immunol. 2018 Sep 15. (via https://www.ncbi.nlm.nih.gov/pubmed/30222508)
Low pathogenic avian influenza virus (AIV) infection in chickens can result in economic losses and has impacts on human health. Poultry vaccination is a tool that can be used to decrease infection and ... Poolkhet C, etc.,al. Exponential random graph models to evaluate the movement of backyard chickens after the avian influenza crisis in 2004~2005, Thailand. Prev Vet Med. 2018 Oct 1;158:71-77.. Abstract
submitted by kickingbird at Sep, 20, 2018 from Prev Vet Med. 2018 Oct 1;158:71-77. (via https://www.ncbi.nlm.nih.gov/pubmed/30220398)
The aim of this study was to use exponential random graph models (ERGMs) to explain networks of movement of backyard chickens in provinces which had been hotspots for avian influenza outbreaks in Thailand ... Phillips AM, etc.,al. Destabilized adaptive influenza variants critical for innate immune system escape are potentiated by host chaperones. PLoS Biol. 2018 Sep 17;16(9):e3000008. Abstract
submitted by kickingbird at Sep, 20, 2018 from PLoS Biol. 2018 Sep 17;16(9):e3000008 (via https://www.ncbi.nlm.nih.gov/pubmed/30222731)
The threat of viral pandemics demands a comprehensive understanding of evolution at the host-pathogen interface. Here, we show that the accessibility of adaptive mutations in influenza nucleoprotein at ... 5584 items, 20/Page, Page[148/280][|<<] [|<] [141] [142] [143] [144] [145] [146] [147] [148] [149] [150] [>|] [>>|] |
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