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2024-7-18 5:41:46
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Zhou P, etc.,al. PB2 E627K or D701N substitution does not change the virulence of canine influenza virus H3N2 in mice and dogs. Vet Microbiol. 2018 Jul;220:67-72..  Abstract  
submitted by kickingbird at Jun, 13, 2018 from Vet Microbiol. 2018 Jul;220:67-72. (via https://www.ncbi.nlm.nih.gov/pubmed/29885803)
Recently, canine influenza virus H3N2 (CIV H3N2) has circulated continuously in the dog populations of Asia and the United States (US). As humans have close contact with pet dogs, the circulation of CIV ...

Seekings AH, etc.,al. Direct evidence of H7N7 avian influenza virus mutation from low to high virulence on a single poultry premises during an outbreak in free range chickens in the UK, 2008. Infect Genet Evol. 2018 Jun 5. pii: S1567-1348(18).  Abstract  
submitted by kickingbird at Jun, 13, 2018 from Infect Genet Evol. 2018 Jun 5. pii: S1567-1348(18) (via https://www.ncbi.nlm.nih.gov/pubmed/29883773)
H5 and H7 subtypes of low pathogenicity avian influenza viruses (LPAIVs) have the potential to evolve into highly pathogenic avian influenza viruses (HPAIVs), causing high mortality in galliforme poultry ...

Sologuren I, etc.,al. Lethal Influenza in Two Related Adults with Inherited GATA2 Deficiency. J Clin Immunol. 2018 Jun 7.  Abstract  
submitted by kickingbird at Jun, 13, 2018 from J Clin Immunol. 2018 Jun 7 (via https://www.ncbi.nlm.nih.gov/pubmed/29882021)
The pathogenesis of life-threatening influenza A virus (IAV) disease remains elusive, as infection is benign in most individuals. We studied two relatives who died from influenza. We Sanger sequenced GATA2 ...

Thomas M, etc.,al. Comparison of Porcine Airway and Intestinal Epithelial Cell Lines for the Susceptibility and Expression of Pattern Recognition Receptors upon Influenza Virus Infection. Viruses. 2018 Jun 7;10(6)..  Abstract  
submitted by kickingbird at Jun, 13, 2018 from Viruses. 2018 Jun 7;10(6). (via https://www.ncbi.nlm.nih.gov/pubmed/29880757)
Influenza viruses infect the epithelial cells of the swine respiratory tract. Cell lines derived from the respiratory tract of pigs could serve as an excellent in vitro model for studying the pathogenesis ...

Fan X, etc.,al. Intranasal inoculate of influenza virus vaccine against lethal virus challenge. Vaccine. 2018 Jun 4. pii: S0264-410X(18)30739-.  Abstract  
submitted by kickingbird at Jun, 13, 2018 from Vaccine. 2018 Jun 4. pii: S0264-410X(18)30739- (via https://www.ncbi.nlm.nih.gov/pubmed/29880240)
Vaccine adjuvants are essential for enhancing immune responses during vaccination. However, only a limited number of safe and effective adjuvants, especially mucosal adjuvants, are available for use in ...

Houlihan C, Frampton D, Ferns RB, Raffle J, et al. The use of whole genome sequencing in the investigation of a nosocomial influenza virus outbreak. J Infect Dis 2018 Jun 5.  Abstract  
submitted by kickingbird at Jun, 10, 2018 from J Infect Dis 2018 Jun 5 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29873767/)
Traditional epidemiological investigation of nosocomial transmission of influenza involves the identification of patients who have the same influenza virus type and who have overlapped in time and place. ...

Putri K, Wawegama N, Ignjatovic J, Noormohammadi A. Characterisation of the antigenic epitopes in the subunit 2 haemagglutinin of avian influenza virus H5N1. Arch Virol 2018 Jun 4.  Abstract  
submitted by kickingbird at Jun, 10, 2018 from Arch Virol 2018 Jun 4 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29869036/)
Monitoring avian influenza (AI) infection and detecting silent infection in vaccinated chickens has been challenging due to the lack of effective serological diagnostic assays to differentiate between ...

Karen A Kormuth, etc.,al. Influenza Virus Infectivity Is Retained in Aerosols and Droplets Independent of Relative Humidity. The Journal of Infectious Diseases, 07 June 2018.  Abstract  
submitted by kickingbird at Jun, 8, 2018 from The Journal of Infectious Diseases, 07 June 2018 (via https://academic.oup.com/jid/advance-article/doi/10.1093/inf)
Pandemic and seasonal influenza viruses can be transmitted through aerosols and droplets, in which viruses must remain stable and infectious across a wide range of environmental conditions. Using humidity-controlled ...

Zhang F, Wang S, Wang Y, Shang X, Zhou H, Cai L. Characterization of pseudoparticles paired with hemagglutinin and neuraminidase from highly pathogenic H5N1 influenza and avian influenza A (H7N9) viruses. Virus Res. 2018 May 31;253:20-27.  Abstract  
submitted by kickingbird at Jun, 7, 2018 from Virus Res. 2018 May 31;253:20-27 (via https://www.ncbi.nlm.nih.gov/pubmed/29859234)
The reassortment of two highly pathogenic avian influenza (HPAI) H5N1 and H7N9 viruses presents a potential challenge to human health. The hemagglutinins (HAs) and neuraminidases (NAs) of these simultaneously ...

Luo J, etc.,al. Comparative pathogenesis of H3N2 canine influenza virus in beagle dogs challenged by intranasal and intratracheal inoculation. Virus Res. 2018 May 31.  Abstract  
submitted by kickingbird at Jun, 7, 2018 from Virus Res. 2018 May 31 (via https://www.ncbi.nlm.nih.gov/pubmed/29860092)
As important companion animals, dogs may serve as intermediate hosts for transmitting influenza virus to humans. However, knowledge regarding H3N2 canine influenza virus (CIV) pathogenicity is not comprehensive, ...

Wu H, Sun N, Song W, Zhu L, Chen H, Cai Z. Identification of different hemagglutinin isoforms of influenza A virus H1N1. Rapid Commun Mass Spectrom. 2018 Jun 1.  Abstract  
submitted by kickingbird at Jun, 7, 2018 from Rapid Commun Mass Spectrom. 2018 Jun 1 (via https://www.ncbi.nlm.nih.gov/pubmed/29857349)
RATIONALE: Influenza A viruses (IAVs) still threaten human health and life. The process of virus infection involves a series of biological regulations, such as signal transduction that may be closely linked ...

Astill J, etc.,al. Examination of the effects of virus inactivation methods on the induction of antibody- and cell-mediated immune responses against whole inactivated H9N2 avian influenza virus vaccines in chickens. Vaccine. 2018 May 28. pii: S0264-410X(18)30759-X.  Abstract  
submitted by kickingbird at Jun, 7, 2018 from Vaccine. 2018 May 28. pii: S0264-410X(18)30759-X (via https://www.ncbi.nlm.nih.gov/pubmed/29853199)
Several types of avian influenza virus (AIV) vaccines exist, including live-attenuated, vectored, and whole inactivated virus (WIV) vaccines. Inactivated vaccines offer some advantages compared to other ...

Thi Nguyen D, etc.,al. Antigenic characterization of highly pathogenic avian influenza A(H5N1) viruses with chicken and ferret antisera reveals clade-dependent variation in hemagglutination inhibition profiles. Emerg Microbes Infect. 2018 May 31;7(1):100.  Abstract  
submitted by kickingbird at Jun, 7, 2018 from Emerg Microbes Infect. 2018 May 31;7(1):100 (via https://www.ncbi.nlm.nih.gov/pubmed/29855467)
Highly pathogenic avian influenza (HPAI) A(H5N1) viruses pose a significant economic burden to the poultry industry worldwide and have pandemic potential. Poultry vaccination against HPAI A(H5N1) viruses ...

Sun X, Pulit-Penaloza JA, Belser JA, Pappas C, et. Pathogenesis and transmission of genetically diverse swine-origin H3N2v influenza A viruses from multiple lineages isolated in the United States, 2011-2016. J Virol 2018 May 30.  Abstract  
submitted by kickingbird at Jun, 3, 2018 from J Virol 2018 May 30 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29848587/)
While several swine-origin influenza A H3N2 variant (H3N2v) viruses isolated from humans prior to 2011 have been previously characterized for their virulence and transmissibility in ferrets, recent genetic ...

Yang H, Carney PJ, Chang JC, Guo Z, et al. Structural and Molecular Characterization of the Hemagglutinin from the Fifth Epidemic Wave A(H7N9) Influenza Viruses. J Virol 2018 May 30.  Abstract  
submitted by kickingbird at Jun, 3, 2018 from J Virol 2018 May 30 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29848588/)
The avian influenza A(H7N9) virus continues to cause human infections in China and is a major ongoing public health concern. Five epidemic waves of A(H7N9) infection have occurred since 2013, and the recent ...

Wenda Guan, etc.,al. Clinical Correlations of Transcriptional Profile in Patients Infected with Avian Influenza H7N9 Virus. The Journal of Infectious Diseases 28 May 2018.  Abstract  
submitted by kickingbird at Jun, 2, 2018 from The Journal of Infectious Diseases 28 May 2018 (via https://academic.oup.com/jid/advance-article/doi/10.1093/inf)
BackgroundAvian influenza A (H7N9) viruses emerged in China in 2013 and caused zoonotic disease associated with a case-fatality ratio of over 30%. Transcriptional profiles in peripheral blood reflect host ...

Chen L, Lee D, Liu Y, Li W, Swayne DE, Chang J, et. Reassortant Clade 2.3.4.4 of Highly Pathogenic Avian Influenza A(H5N6) Virus, Taiwan, 2017. Emerg Infect Dis. 2018;24(6):1147-1149.  Abstract  
submitted by kickingbird at Jun, 2, 2018 from Emerg Infect Dis. 2018;24(6):1147-1149 (via https://wwwnc.cdc.gov/eid/article/24/6/17-2071_article)
A highly pathogenic avian influenza A(H5N6) virus of clade 2.3.4.4 was detected in a domestic duck found dead in Taiwan during February 2017. The endemic situation and continued evolution of various reassortant ...

Muralidharan A, Gravel C, Duran A, Larocque L, et. Identification of immunodominant CD8 epitope in the stalk domain of influenza B viral hemagglutinin. Biochem Biophys Res Commun 2018 May 21.  Abstract  
submitted by kickingbird at May, 29, 2018 from Biochem Biophys Res Commun 2018 May 21 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29792863/)
Human infections by type B influenza virus constitute about 25% of all influenza cases. The viral hemagglutinin is comprised of two subunits, HA1 and HA2. While HA1 is constantly evolving in an unpredictable ...

Ping He, etc.,al. Novel triple-reassortant influenza viruses in pigs, Guangxi, China. Emerging Microbes & Infectionsvolume 7, Article nu.  Abstract  
submitted by kickingbird at May, 29, 2018 from Emerging Microbes & Infectionsvolume 7, Article nu (via https://www.nature.com/articles/s41426-018-0088-z)
Considered a “mixing vessel” for influenza viruses, pigs can give rise to new influenza virus reassortants that can threaten humans. During our surveillance of pigs in Guangxi, China from 2013 to 2015, ...

Belser JA, Barclay W, Barr I, Fouchier RAM, Matsuy. Ferrets as Models for Influenza Virus Transmission Studies and Pandemic Risk Assessments. Emerg Infect Dis. 2018 Jun;24(6):965-971.  Abstract  
submitted by kickingbird at May, 23, 2018 from Emerg Infect Dis. 2018 Jun;24(6):965-971 (via https://www.ncbi.nlm.nih.gov/pubmed/29774862)
The ferret transmission model is extensively used to assess the pandemic potential of emerging influenza viruses, yet experimental conditions and reported results vary among laboratories. Such variation ...

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