-

nihao guest [ sign in / register ]
2024-3-29 14:02:20
Article

Sun H, Yao W, Wang K, Qian Y, et al.. Inhibition of neddylation pathway represses influenza virus replication and pro-inflammatory responses. Virology 2017;514:230-239.  Abstract  
submitted by kickingbird at Dec, 31, 2017 from Virology 2017;514:230-239 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29248752/)
The neddylation pathway belongs post-translational modifications and plays important roles in regulating viral infection and replication. To address the relationship of influenza A virus with the neddylation ...

Raymond DD, Bajic G, Ferdman J, Suphaphiphat P, et. Conserved epitope on influenza-virus hemagglutinin head defined by a vaccine-induced antibody. Proc Natl Acad Sci U S A 2017 Dec 18.  Abstract  
submitted by kickingbird at Dec, 31, 2017 from Proc Natl Acad Sci U S A 2017 Dec 18 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29255041/)
Circulating influenza viruses evade neutralization in their human hosts by acquiring escape mutations at epitopes of prevalent antibodies. A goal for next-generation influenza vaccines is to reduce escape ...

Williams JA, Gui L, Hom N, Mileant A, et al. Dissection of epitope-specific mechanisms of neutralization of influenza virus by intact IgG and Fab fragments. J Virol 2017 Dec 20.  Abstract  
submitted by kickingbird at Dec, 31, 2017 from J Virol 2017 Dec 20 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29263254/)
The neutralizing antibody (nAb) response against the influenza virus's hemagglutinin (HA) fusion glycoprotein is important for preventing viral infection, but we lack a comprehensive understanding of the ...

Zhang J, Lao G, Zhang R, Wei Z, et al. Genetic diversity and dissemination pathways of highly pathogenic H5N6 avian influenza viruses from birds in Southwestern China along the East Asian–Australian migration flyway. J Infect 2017 Dec 12.  Abstract  
submitted by kickingbird at Dec, 31, 2017 from J Infect 2017 Dec 12 (via http://www.journalofinfection.com/article/S0163-4453(17)3038)
Gao and her colleagues recently reported in this journal the increasing genetic diversity of novel H5N6 avian influenza viruses (AIVs) persisting in Guangdong Province of China, which posed the serious ...

Hornick EE, Banoth B, Miller AM, Zacharias ZR, et. Nlrp12 Mediates Adverse Neutrophil Recruitment during Influenza Virus Infection. J Immunol 2017 Dec 27.  Abstract  
submitted by kickingbird at Dec, 31, 2017 from J Immunol 2017 Dec 27 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29282312/)
Exaggerated inflammatory responses during influenza A virus (IAV) infection are typically associated with severe disease. Neutrophils are among the immune cells that can drive this excessive and detrimental ...

Bhoye D, Cherian SS. Computational analysis of the effect of polymerase acidic (PA) gene mutation F35L in the 2009 pandemic influenza A (H1N1) virus on binding aspects of mononucleotides in the endonuclease domain. Arch Virol 2017 Dec 22.  Abstract  
submitted by kickingbird at Dec, 31, 2017 from Arch Virol 2017 Dec 22 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29273880/)
An F35L mutation in the N-terminal domain of the polymerase acidic protein (PA-Nter), which contains the active site of the endonuclease, has been reported to result in higher polymerase activity in mouse-adapted ...

Yang JR, Cheng CY, Chen CY, Lin CH, et al. A virus-like particle vaccination strategy expands its tolerance to H3N2 antigenic drift by enhancing neutralizing antibodies against hemagglutinin stalk. Antiviral Res 2017;140:62-75.  Abstract  
submitted by kickingbird at Dec, 31, 2017 from Antiviral Res 2017;140:62-75 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28093338/)
Seasonal influenza viruses impact public health annually due to their continual evolution. However, the current inactivated seasonal vaccines provide poor protection against antigenically drifted viruses ...

Li-Juan Zhang, Li Xia, Shu-Lin Liu, En-Ze Sun, Qiu. A “Driver Switchover” Mechanism of Influenza Virus Transport from Microfilaments to Microtubules. ACS Nano Publication Date (Web): December 12, 2017.  Abstract  
submitted by kickingbird at Dec, 25, 2017 from ACS Nano Publication Date (Web): December 12, 2017 (via http://pubs.acs.org/doi/10.1021/acsnano.7b06926)
When infecting host cells, influenza virus must move on microfilaments (MFs) at the cell periphery and then move along microtubules (MTs) through the cytosol to reach the perinuclear region for genome ...

Chen L, Wang C, Luo J, Su W, Li M, Zhao N, Lyu W,. Histone Deacetylase 1 Plays an Acetylation-Independent Role in Influenza A Virus Replication. Front. Immunol., 12 December 2017.  Abstract  
submitted by kickingbird at Dec, 24, 2017 from Front. Immunol., 12 December 2017 (via https://www.frontiersin.org/articles/10.3389/fimmu.2017.0175)
Influenza A viruses (IAVs) take advantage of the host acetylation system for their own benefit. Whether the nucleoprotein (NP) of IAVs undergoes acetylation and the interaction between the NP and the class ...

Belser JA, Brock N, Sun X, Jones J, Zanders N, Hod. Mammalian Pathogenesis and Transmission of Avian Influenza A(H7N9) Viruses, Tennessee, USA, 2017. Emerg Infect Dis. 2018 Jan;24(1):149-152.  Abstract  
submitted by kickingbird at Dec, 24, 2017 from Emerg Infect Dis. 2018 Jan;24(1):149-152 (via https://wwwnc.cdc.gov/eid/article/24/1/17-1574_article)
Infections with low pathogenicity and highly pathogenic avian influenza A(H7N9) viruses affected poultry in 4 states in the southeastern United States in 2017. We evaluated pathogenicity and transmission ...

Y Yan, Y Du, G Wang, K Li. Non-structural protein 1 of H3N2 influenza A virus induces nucleolar stress via interaction with nucleolin. Scientific Reports 7, Article number: 17761 (2017).  Abstract  
submitted by kickingbird at Dec, 24, 2017 from Scientific Reports 7, Article number: 17761 (2017) (via http://www.nature.com/articles/s41598-017-18087-2)
The nucleolus is a stress sensor associated with cell cycle progression and a central hub for the replication of pathogenic RNA viruses. However, the role of nucleolus in influenza A virus infection ...

Luo S, et al. surveillance of live poultry markets for low pathogenic avian influenza viruses in guangxi province, southern china, from 2012~2015. Sci Rep. 2017.  Abstract  
submitted by kickingbird at Dec, 19, 2017 from Sci Rep. 2017 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29242521/)
Infections with low pathogenic avian influenza viruses (LPAIVs) can be mild or asymptomatic in poultry; however, in humans, LPAIVs can cause severe infections and death, as demonstrated by the H7N9 and ...

Herrera-Rodriguez J, Meijerhof T, Niesters HG, Stj. A novel peptide-based vaccine candidate with protective efficacy against influenza A in a mouse model. Virology 2017;515:21-28.  Abstract  
submitted by kickingbird at Dec, 18, 2017 from Virology 2017;515:21-28 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29223787/)
Current influenza vaccines mainly induce antibody responses to the variable hemagglutinin proteins of the virus strains included in the vaccine. Instead, a broadly protective influenza vaccine should aim ...

Turkington HL, Juozapaitis M, Tsolakos N, Corrales. Unexpected Functional Divergence of Bat Influenza Virus NS1 Proteins. J Virol 2017 Dec 13.  Abstract  
submitted by kickingbird at Dec, 18, 2017 from J Virol 2017 Dec 13 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29237829/)
Recently, two influenza A virus (FLUAV) genomes were identified in Central and South American bats. These sequences exhibit notable divergence from classical FLUAV counterparts, and functionally, bat FLUAV ...

Chauche C, Nogales A, Zhu H, Goldfarb D, et al. Mammalian adaptation of an avian influenza A virus involves stepwise changes in NS1. J Virol 2017 Dec 13.  Abstract  
submitted by kickingbird at Dec, 18, 2017 from J Virol 2017 Dec 13 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29237841/)
Influenza A viruses (IAVs) are common pathogens of birds that occasionally establish endemic infections in mammals. The processes and mechanisms that result in IAV mammalian adaptation are poorly understood. ...

Amodio D, Cotugno N, Macchiarulo G, Rocca S, et al. Quantitative Multiplexed Imaging Analysis Reveals a Strong Association between Immunogen-Specific B Cell Responses and Tonsillar Germinal Center Immune Dynamics in Children after Influenza Vaccination. J Immunol 2017 Dec 13.  Abstract  
submitted by kickingbird at Dec, 18, 2017 from J Immunol 2017 Dec 13 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29237774/)
Generation of Ag-specific humoral responses requires the orchestrated development and function of highly specialized immune cells in secondary lymphoid organs. We used a multiparametric approach combining ...

White MC, Lowen AC. Implications of segment mismatch for influenza A virus evolution. J Gen Virol 2017 Dec 15.  Abstract  
submitted by kickingbird at Dec, 18, 2017 from J Gen Virol 2017 Dec 15 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29244017/)
Influenza A virus (IAV) is an RNA virus with a segmented genome. These viral properties allow for the rapid evolution of IAV under selective pressure, due to mutation occurring from error-prone replication ...

Yang L, Zhu W, Li X, Chen M, et al. Genesis and Spread of Newly Emerged Highly Pathogenic H7N9 Avian Viruses in Mainland China. J Virol 2017;91.  Abstract  
submitted by kickingbird at Dec, 10, 2017 from J Virol 2017;91 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28956760/)
The novel low-pathogenic avian influenza A H7N9 viruses (LPAI H7N9 viruses) have been a threat to public health since their emergence in 2013 because of the high rates of mortality and morbidity that they ...

Iwatsuki-Horimoto K, Nakajima N, Ichiko Y, Sakai-T. Syrian hamster as an animal model for the study of human influenza virus infection. J Virol 2017 Dec 6.  Abstract  
submitted by kickingbird at Dec, 10, 2017 from J Virol 2017 Dec 6 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29212926/)
Ferrets and mice are frequently used as animal models for influenza research. However, ferrets are demanding in terms of housing space and handling, whereas mice are not naturally susceptible to infection ...

Zhong G, Le MQ, Lopes TJS, Halfmann P, et al. Mutations in the PA Protein of Avian H5N1 Influenza Viruses Affect Polymerase Activity and Mouse Virule. J Virol 2017 Dec 6.  Abstract  
submitted by kickingbird at Dec, 10, 2017 from J Virol 2017 Dec 6 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29212927/)
To study the influenza viral determinants of pathogenicity, we characterized two highly pathogenic avian H5N1 influenza viruses isolated in Vietnam in 2012 (A/duck/Vietnam/QT1480/2012; QT1480) and 2013 ...

5117 items, 20/Page, Page[146/256][|<<] [|<] [141] [142] [143] [144] [145] [146] [147] [148] [149] [150] [>|] [>>|]

Related Pages:

Browse by Category
Learn about the flu news, articles, events and more
Subscribe to the weekly F.I.C newsletter!


  

Site map  |   Contact us  |  Term of use  |  FAQs |  粤ICP备10094839号-1
Copyright ©www.flu.org.cn. 2004-2024. All Rights Reserved. Powered by FIC 4.0.1
  Email:webmaster@flu.org.cn