Takemae N, Tsunekuni R, Uchida Y, Ito T, Saito T. Experimental infection of pigs with H1 and H3 influenza A viruses of swine by using intranasal nebulization. BMC Vet Res. 2018 Mar 27;14(1):115. Abstract
submitted by kickingbird at Apr, 2, 2018 from BMC Vet Res. 2018 Mar 27;14(1):115 (via https://www.ncbi.nlm.nih.gov/pubmed/29587842)
BACKGROUND: Experimental infection of pigs via direct intranasal or intratracheal inoculation has been mainly used to study the infectious process of influenza A viruses of swine (IAVs-S). Nebulization ... Trapp S, Soubieux D, etc.,al. Major contribution of the RNA-binding domain of NS1 in the pathogenicity and replication potential of an avian H7N1 influenza virus in chickens. Virol J. 2018 Mar 27;15(1):55. Abstract
submitted by kickingbird at Apr, 2, 2018 from Virol J. 2018 Mar 27;15(1):55 (via https://www.ncbi.nlm.nih.gov/pubmed/29587792)
BACKGROUND: Non-structural protein NS1 of influenza A viruses harbours several determinants of pathogenicity and host-range. However it is still unclear to what extent each of its two structured domains ... Cheng J, Zhang C, Tao J, Li B, Shi Y, Liu H. Effects of the S42 residue of the H1N1 swine influenza virus NS1 protein on interferon responses and virus replication. Virol J. 2018 Mar 27;15(1):57. Abstract
submitted by kickingbird at Apr, 2, 2018 from Virol J. 2018 Mar 27;15(1):57 (via https://www.ncbi.nlm.nih.gov/pubmed/29587786)
BACKGROUND: The influenza A virus non-structural protein 1 (NS1) is a multifunctional protein that plays an important role in virus replication, virulence and inhibition of the host antiviral immune response. ... Huang CG, Lee LA, Wu YC, Hsiao MJ. A pilot study on primary cultures of human respiratory tract epithelial cells to predict patients´ responses to H7N9 infection. Oncotarget. 2018 Feb 20;9(18):14492-14508. Abstract
submitted by kickingbird at Apr, 2, 2018 from Oncotarget. 2018 Feb 20;9(18):14492-14508 (via https://www.ncbi.nlm.nih.gov/pubmed/29581859)
Avian influenza A(H7N9) virus infections frequently lead to acute respiratory distress syndrome and death in humans. We aimed to investigate whether primary cultures of human respiratory tract epithelial ... Oh KH, Mo JS, Bae YJ, Lee SB, Lai VD, Wang SJ. Amino acid substitutions in low pathogenic avian influenza virus strains isolated from wild birds in Korea. Virus Genes. 2018 Mar 26. Abstract
submitted by kickingbird at Apr, 2, 2018 from Virus Genes. 2018 Mar 26 (via https://www.ncbi.nlm.nih.gov/pubmed/29582231)
Wild birds are natural hosts and reservoirs for influenza A viruses. However, many species, such as many waterfowl, are asymptomatic when infected and so facilitate the generation of viral genetic diversity. ... Manoj Kumar,etc.,al. Emergence of novel reassortant H6N2 avian influenza viruses in ducks in India. Infect Genet Evol Volume 61, July 2018. Abstract
submitted by kickingbird at Mar, 29, 2018 from Infect Genet Evol Volume 61, July 2018 (via https://www.sciencedirect.com/science/article/pii/S156713481)
The recent reports of human infection due to H6 subtype avian influenza viruses (AIV), which are prevalent in terrestrial poultry, indicate evolution of the virus to a possible pandemic strain. Here, we ... Xian Qi, Xiaofei An, etc.,al. Co-circulation of multiple genotypes of influenza A (H7N9) viruses in eastern China, 2016-2017. Arch Virol 14 March 2018. Abstract
submitted by kickingbird at Mar, 29, 2018 from Arch Virol 14 March 2018 (via https://link.springer.com/article/10.1007/s00705-018-3800-3)
Five epidemic waves of human infection with influenza A (H7N9) virus have emerged in China since spring 2013. We previously described the epidemiological characterization of the fifth wave in Jiangsu province. ... In-Won Lee,etc.,al. Comparison of the virulence and transmissibility of canine H3N2 influenza viruses and characterization of their canine adaptation factors. Emerging Microbes & Infections vol 7,2018. Abstract
submitted by kickingbird at Mar, 29, 2018 from Emerging Microbes & Infections vol 7,2018 (via https://www.nature.com/articles/s41426-017-0013-x)
Recent canine influenza outbreaks have raised concerns about the generation of pathogenic variants that may pose a threat to public health. Here, we examine avian-like H3N2 canine influenza viruses (CIVs) ... McKimm-Breschkin JL, Barrett S, Wong FYK. Identification of Indonesian clade 2.1 highly pathogenic influenza A(H5N1) viruses with N294S and S246N neuraminidase substitutions which further reduce oseltamivir susceptibility. Antiviral Res. 2018 Mar 21. Abstract
submitted by kickingbird at Mar, 29, 2018 from Antiviral Res. 2018 Mar 21 (via https://www.sciencedirect.com/science/article/pii/S016635421)
We have tested the in vitro susceptibility to the neuraminidase (NA) inhibitors of 96 highly pathogenic clade 2.1 A(H5N1) viruses from Indonesia, isolated between 2008 and 2011. HPAI virus samples obtained ... Yang W, Cummings MJ, Bakamutumaho B. Dynamics of Influenza in Tropical Africa: Temperature, Humidity, and Co-circulating (sub)types. Influenza Other Respir Viruses. 2018 Mar 23.. Abstract
submitted by kickingbird at Mar, 29, 2018 from Influenza Other Respir Viruses. 2018 Mar 23. (via https://www.ncbi.nlm.nih.gov/pubmed/29573157)
BACKGROUND: The association of influenza with meteorological variables in tropical climates remains controversial. Here we investigate the impact of weather conditions on influenza in the tropics and factors ... Moore J, Ahmed H, Antia R. High dimensional random walks can appear low dimensional: application to influenza H3N2 evolution. J Theor Biol. 2018 Mar 20. Abstract
submitted by kickingbird at Mar, 29, 2018 from J Theor Biol. 2018 Mar 20 (via https://www.ncbi.nlm.nih.gov/pubmed/29571708)
One important feature of the mammalian immune system is the highly specific binding of antigens to antibodies. Antibodies generated in response to one infection may also provide some level of cross immunity ... Abdul-Cader MS, Ehiremen G, Nagy E, Abdul-Careem. Low pathogenic avian influenza virus infection increases the staining intensity of KUL01+ cells including macrophages yet decrease of the staining intensity of KUL01+ cells using clodronate liposomes. Vet Immunol Immunopathol. 2018 Apr. Abstract
submitted by kickingbird at Mar, 29, 2018 from Vet Immunol Immunopathol. 2018 Apr (via https://www.ncbi.nlm.nih.gov/pubmed/29571516)
The effect of depletion of macrophages using clodronate liposomes as well as macrophage response following viral infections have been studied in various mouse-virus infection models, but they have not ... Nemoto M, Yamanaka T, Bannai H, Tsujimura K, Kokad. Complete Genomic Sequences of H3N8 Equine Influenza Virus Strains Used as Vaccine Strains in Japan. Genome Announc 6:e00172-18. Abstract
submitted by kickingbird at Mar, 29, 2018 from Genome Announc 6:e00172-18 (via http://genomea.asm.org/content/6/12/e00172-18)
We sequenced the eight segments of influenza A virus strains A/equine/Ibaraki/1/2007 and A/equine/Yokohama/aq13/2010, which are strains of the Florida sublineage clades 1 and 2 of the H3N8 subtype equine ... Wang J, Zeng Y, Xu S, Yang J, et al. A Naturally Occurring Deletion in the Effector Domain of H5N1 Swine Influenza Virus Nonstructural Protein 1 Regulates Viral Fitness and Host Innate Immunity. J Virol 2018 Mar 21. Abstract
submitted by kickingbird at Mar, 26, 2018 from J Virol 2018 Mar 21 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29563291/)
Nonstructural protein 1 (NS1) of influenza A virus regulates innate immune responses via various mechanisms. We previously showed that a naturally occurring deletion (the EALQR motif) in the NS1 effector ... Aljurayyan A, Puksuriwong S, Ahmed M, Sharma R, et. Activation and induction of antigen-specific T follicular helper cells (TFH) play a critical role in LAIV-induced human mucosal anti-influenza antibody response. J Virol 2018 Mar 21. Abstract
submitted by kickingbird at Mar, 26, 2018 from J Virol 2018 Mar 21 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29563292/)
There is increasing interest recently in developing intranasal vaccines against respiratory tract infections. Antibody response is critical in vaccine-induced protection and TFH is considered important ... Watanabe Y, Arai Y, Kawashita N, Ibrahim MS, et al. Characterization of H5N1 influenza virus quasispecies with adaptive hemagglutinin mutations from single-virus infections of human airway cells. J Virol 2018 Mar 21. Abstract
submitted by kickingbird at Mar, 26, 2018 from J Virol 2018 Mar 21 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29563293/)
Transmission of avian influenza (AI) viruses to mammals involves phylogenetic bottlenecks that select small numbers of variants for transmission to new host species. However, little is known about the ... Jung KI, Pyo CW, Choi SY. Influenza A virus-induced autophagy contributes to enhancement of virus infectivity by SOD1 downregulation in alveolar epithelial cells. Biochem Biophys Res Commun 2018 Mar 16. Abstract
submitted by kickingbird at Mar, 26, 2018 from Biochem Biophys Res Commun 2018 Mar 16 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29548827/)
Infection with influenza A virus (IAV) A/WSN/1933 (H1N1) causes oxidative stress and severe lung injury. We have demonstrated that the generation of reactive oxygen species (ROS) during IAV infection is ... Cao X, Liu X, Zheng S, Xu L, et al.. Isolation and characterization of an avian-origin H3N8 canine influenza virus from a dog in eastern China. Arch Virol 2018 Mar 20. Abstract
submitted by kickingbird at Mar, 26, 2018 from Arch Virol 2018 Mar 20 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29556821/)
Previous studies have shown that dogs are susceptible to influenza A viruses, and the close contact between dogs and humans poses a threat to public health. In 2015, a novel H3N8 influenza virus was isolated ... S. Yamayoshi, etc.,al. Enhanced Replication of Highly Pathogenic Influenza A(H7N9) Virus in Humans. EID Vol 24, No. 4. Abstract
submitted by kickingbird at Mar, 22, 2018 from EID Vol 24, No. 4 (via https://wwwnc.cdc.gov/eid/article/24/4/17-1509_article)
To clarify the threat posed by emergence of highly pathogenic influenza A(H7N9) virus infection among humans, we characterized the viral polymerase complex. Polymerase basic 2–482R, polymerase basic 2–588V, ... Brianne J. Lindsay, etc.,al. Morphological characterization of a plant-made virus-like particle vaccine bearing influenza virus hemagglutinins by electron microscopy. Vaccine 14 March 2018. Abstract
submitted by kickingbird at Mar, 22, 2018 from Vaccine 14 March 2018 (via https://www.sciencedirect.com/science/article/pii/S0264410X1)
Plant-made virus-like particle (VLP) vaccines that display wild-type influenza hemagglutinin (HA) are rapidly advancing through clinical trials. Produced by transient transfection of Nicotiana benthamiana, ... 5156 items, 20/Page, Page[144/258][|<<] [|<] [141] [142] [143] [144] [145] [146] [147] [148] [149] [150] [>|] [>>|] |
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