Du W, Dai M, Li Z, Boons GJ, Peeters B, van K. Substrate binding by the 2nd sialic acid-binding site of influenza A virus N1 neuraminidase contributes to enzymatic activity. J Virol. 2018 Aug 8.. Abstract
submitted by kickingbird at Aug, 11, 2018 from J Virol. 2018 Aug 8. (via https://www.ncbi.nlm.nih.gov/pubmed/30089692)
The influenza A virus (IAV) neuraminidase (NA) protein plays an essential role in the release of virus particles from cells and decoy receptors. The NA enzymatic activity presumably needs to match the ... Zhao M, etc.,al. Heterosubtypic Protections against Human-Infecting Avian Influenza Viruses Correlate to Biased Cross-T-Cell Responses. MBio. 2018 Aug 7;9(4).. Abstract
submitted by kickingbird at Aug, 11, 2018 from MBio. 2018 Aug 7;9(4). (via https://www.ncbi.nlm.nih.gov/pubmed/30087171)
Against a backdrop of seasonal influenza virus epidemics, emerging avian influenza viruses (AIVs) occasionally jump from birds to humans, posing a public health risk, especially with the recent sharp increase ... Lambertz RLO, Pippel J, Gerhauser I, Kollmus H. Exchange of amino acids in the H1-haemagglutinin to H3 residues is required for efficient influenza A virus replication and pathology in Tmprss2 knock-out mice. J Gen Virol. 2018 Aug 6.. Abstract
submitted by kickingbird at Aug, 11, 2018 from J Gen Virol. 2018 Aug 6. (via https://www.ncbi.nlm.nih.gov/pubmed/30084768)
The haemagglutinin (HA) of H1N1 and H3N2 influenza A virus (IAV) subtypes has to be activated by host proteases. Previous studies showed that H1N1 virus cannot replicate efficiently in Tmprss2-/- knock-out ... Loy H, Kuok DIT, Hui KPY, Choi MHL, Yuen W. Therapeutic implications of human umbilical cord mesenchymal stromal cells in attenuating influenza A/H5N1-associated acute lung injury. J Infect Dis. 2018 Aug 2.. Abstract
submitted by kickingbird at Aug, 11, 2018 from J Infect Dis. 2018 Aug 2. (via https://www.ncbi.nlm.nih.gov/pubmed/30085072)
Background: Highly pathogenic avian influenza viruses can cause severe forms of acute lung injury (ALI) in humans, where pulmonary flooding leads to respiratory failure. Therapeutic benefits of bone-marrow ... Song L, Xiong D, Hu M, Jiao X, Pan Z. Enhanced Th1/Th2 mixed immune responses elicited by polyethyleneimine adjuvanted influenza A (H7N9) antigen HA1-2 in chickens. Poult Sci. 2018 Aug 1. Abstract
submitted by kickingbird at Aug, 11, 2018 from Poult Sci. 2018 Aug 1 (via https://www.ncbi.nlm.nih.gov/pubmed/30085299)
Influenza A (H7N9) viruses have caused severe human infections and deaths every year in China since 2013. To reduce the risk of human infection and prevent a new influenza pandemic, there is a pressing ... Grech-Angelini S, Hervé S, Rose N, Barbier N. Serological survey of influenza A viruses in domestic and wild Suidae in Corsica (France), a Mediterranean island environment.. Prev Vet Med. 2018 Sep 1;157:94-98.. Abstract
submitted by kickingbird at Aug, 11, 2018 from Prev Vet Med. 2018 Sep 1;157:94-98. (via https://www.ncbi.nlm.nih.gov/pubmed/30086855)
Corsica is a mountainous French island in the north-western Mediterranean Sea. It is a rural area, where pig farming is a major economic activity. Although no acute respiratory outbreaks due to swine influenza ... Kuchipudi SV, Nissly RH. Novel Flu Viruses in Bats and Cattle:. Vet Sci. 2018 Aug 6;5(3). Abstract
submitted by kickingbird at Aug, 11, 2018 from Vet Sci. 2018 Aug 6;5(3) (via https://www.ncbi.nlm.nih.gov/pubmed/30082582)
Influenza viruses are among the major infectious disease threats of animal and human health. This review examines the recent discovery of novel influenza viruses in bats and cattle, the evolving complexity ... Ferro S, Gitto R, Buemi MR, Karamanou S. Identification of influenza PA-Nter endonuclease inhibitors using pharmacophore- and docking-based virtual screening. Bioorg Med Chem. 2018 Jul 27.. Abstract
submitted by kickingbird at Aug, 11, 2018 from Bioorg Med Chem. 2018 Jul 27. (via https://www.ncbi.nlm.nih.gov/pubmed/30082105)
Searching for new antiviral agents, we focused our interest on the influenza PA-Nter endonuclease. Therefore, we developed a three-dimensional pharmacophore model which contains the binding features addressed ... Lyons DM, Lauring AS. Mutation and Epistasis in Influenza Virus Evolution. Viruses. 2018 Aug 3;10(8).. Abstract
submitted by kickingbird at Aug, 11, 2018 from Viruses. 2018 Aug 3;10(8). (via https://www.ncbi.nlm.nih.gov/pubmed/30081492)
Influenza remains a persistent public health challenge, because the rapid evolution of influenza viruses has led to marginal vaccine efficacy, antiviral resistance, and the annual emergence of novel strains. ... Liu J, Ren Z, Wang H, Zhao Y, Wilker PR, Yu Z. Influenza virus-like particles composed of conserved influenza proteins and GPI-anchored CCL28/GM-CSF fusion proteins enhance protective immunity against homologous and heterologous viruses. Int Immunopharmacol. 2018 Aug 3;63:119-128.. Abstract
submitted by kickingbird at Aug, 8, 2018 from Int Immunopharmacol. 2018 Aug 3;63:119-128. (via https://www.ncbi.nlm.nih.gov/pubmed/30081250)
Influenza viruses cause significant morbidity and mortality and pose a substantial threat to public health. Vaccination represents the principle means of preventing influenza virus infection. Current vaccine ... Chen TH, Liu WC, Lin CY, Liu CC, Jan JT, Spearman. Glycan-masking hemagglutinin antigens from stable CHO cell clones for H5N1 avian influenza vaccine development. Biotechnol Bioeng. 2018 Aug 6.. Abstract
submitted by kickingbird at Aug, 8, 2018 from Biotechnol Bioeng. 2018 Aug 6. (via https://www.ncbi.nlm.nih.gov/pubmed/30080931)
Refocusing of B cell responses can be achieved by preserving the overall fold of the antigen structure but selectively mutating the undesired antigenic sites with additional N-linked glycosylation motifs ... Ruan BY, Wen F, Gong XQ, Liu XM, Wang Q, Yu L. Protective efficacy of a high-growth reassortant H1N1 influenza virus vaccine against the European Avian-like H1N1 swine influenza virus in mice and pigs. Vet Microbiol. 2018 Aug;222:75-84.. Abstract
submitted by kickingbird at Aug, 8, 2018 from Vet Microbiol. 2018 Aug;222:75-84. (via https://www.ncbi.nlm.nih.gov/pubmed/30080677)
Swine influenza A viruses (SIVs) causing outbreaks of acute, highly contagious respiratory disease in pigs also pose a potential threat to public health. European avian-like H1N1 (EA H1N1) SIVs are the ... Li X, Liu B, Ma S, Cui P, Liu W, Li Y, Guo J, Chen. High frequency of reassortment after co-infection of chickens with the H4N6 and H9N2 influenza A viruses and the biological characteristics of the reassortants. Vet Microbiol. 2018 Aug;222:11-17. Abstract
submitted by kickingbird at Aug, 8, 2018 from Vet Microbiol. 2018 Aug;222:11-17 (via https://www.ncbi.nlm.nih.gov/pubmed/30080665)
H4 and H9 avian influenza viruses (AIVs) are two of the most prevalent influenza viruses worldwide. The co-existence of H4 and H9 viruses in multiple avian species provides an opportunity for the generation ... Cooper GE, Ostridge K, Khakoo SI, Wilkinson T. Human CD49a+ Lung Natural Killer Cell Cytotoxicity in Response to Influenza A Virus. Front Immunol. 2018 Jul 20;9:1671.. Abstract
submitted by kickingbird at Aug, 8, 2018 from Front Immunol. 2018 Jul 20;9:1671. (via https://www.ncbi.nlm.nih.gov/pubmed/30079068)
Influenza A virus (IAV) is a major global public health burden due to its routine evasion of immunization strategies. Natural killer (NK) cells are innate cytotoxic cells with important antiviral activity ... Dou D, Revol R, ?stbye H, Wang H, Daniels R. Influenza A Virus Cell Entry, Replication, Virion Assembly and Movement. Front Immunol. 2018 Jul 20;9:1581. Abstract
submitted by kickingbird at Aug, 8, 2018 from Front Immunol. 2018 Jul 20;9:1581 (via https://www.ncbi.nlm.nih.gov/pubmed/30079062)
Influenza viruses replicate within the nucleus of the host cell. This uncommon RNA virus trait provides influenza with the advantage of access to the nuclear machinery during replication. However, it also ... Lubna NJ, Nakamura Y, Hagiwara-Nagasawa M. Electropharmacological characterization of microminipigs as a laboratory animal using anti-influenza virus drug oseltamivir. J Toxicol Sci. 2018;43(8):507-512. Abstract
submitted by kickingbird at Aug, 8, 2018 from J Toxicol Sci. 2018;43(8):507-512 (via https://www.ncbi.nlm.nih.gov/pubmed/30078836)
We analyzed electropharmacological characteristics of microminipigs under halothane-anesthesia using anti-influenza virus drug oseltamivir, which has been known to possess multi-channel blocking properties, ... Xu J, Li S, Wang X, Liu J, Shan P, Zhou Y. Systemic and mucosal humoral immune responses induced by the JY-adjuvanted nasal spray H7N9 vaccine in mice. Emerg Microbes Infect. 2018 Aug 3;7(1):140. Abstract
submitted by kickingbird at Aug, 8, 2018 from Emerg Microbes Infect. 2018 Aug 3;7(1):140 (via https://www.ncbi.nlm.nih.gov/pubmed/30076293)
Since the first case of human avian influenza A (H7N9) virus infection in 2013, five H7N9 epidemics have occurred in China, all of which caused severe diseases, including pneumonia and acute respiratory ... Suttie A, etc.,al. Influenza A(H5N1) viruses with A(H9N2) single gene (matrix or PB1) reassortment isolated from Cambodian live bird markets. Virology. 2018 Jul 31;523:22-26. Abstract
submitted by kickingbird at Aug, 8, 2018 from Virology. 2018 Jul 31;523:22-26 (via https://www.ncbi.nlm.nih.gov/pubmed/30075357)
Live bird market surveillance for avian influenza viruses in Cambodia in 2015 has led to the detection of two 7:1 reassortant influenza A(H5N1) clade 2.3.2.1c viruses. These reassortant strains, designated ... Yamasaki M, Okada T, Sumimoto Y, Hattori N. Influenza infection presenting with pulmonary congestion: influenza myocarditis. Respirol Case Rep. 2018 Jul 30;6(7):e00352. Abstract
submitted by kickingbird at Aug, 8, 2018 from Respirol Case Rep. 2018 Jul 30;6(7):e00352 (via https://www.ncbi.nlm.nih.gov/pubmed/30073086)
Influenza myocarditis is a rare but life-threatening complication of influenza infection. Pneumonitis is a well-known complication of influenza infection, and chest computed tomography (CT) is useful for ... Agustiningsih A, Trimarsanto H, etc.,al. Evolutionary study and phylodynamic pattern of human influenza A/H3N2 virus in Indonesia from 2008 to 2010. PLoS One. 2018 Aug 1;13(8):e0201427.. Abstract
submitted by kickingbird at Aug, 5, 2018 from PLoS One. 2018 Aug 1;13(8):e0201427. (via https://www.ncbi.nlm.nih.gov/pubmed/30067808)
Influenza viruses are by nature unstable with high levels of mutations. The sequential accumulation of mutations in the surface glycoproteins allows the virus to evade the neutralizing antibodies. The ... 5159 items, 20/Page, Page[134/258][|<<] [|<] [131] [132] [133] [134] [135] [136] [137] [138] [139] [140] [>|] [>>|] |
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