Shuk Hang Li, etc.,al. [preprint]Childhood immunological imprinting of cross-subtype antibodies targeting the hemagglutinin head domain of influenza viruses. https://doi.org/10.1101/2025.09.24.25335646. Abstract
submitted by kickingbird at Sep, 28, 2025 from https://doi.org/10.1101/2025.09.24.25335646 (via https://www.medrxiv.org/content/10.1101/2025.09.24.25335646v)
Influenza virus cross-subtype antibodies targeting the hemagglutinin (HA) head are rare. Here, we found that a large proportion of monoclonal antibodies (mAbs) isolated from individuals immunized with ... Kim YI, Jang SG, Kwon W, Kim J, Park D, Choi I, Ch. PB2 and NP of North American H5N1 virus drive immune cell replication and systemic infections. Sci Adv. 2025 Sep 26;11(39):eady1208. Abstract
submitted by kickingbird at Sep, 27, 2025 from Sci Adv. 2025 Sep 26;11(39):eady1208 (via https://www.science.org/doi/10.1126/sciadv.ady1208)
The 2022 North American outbreak of 2.3.4.4b H5N1 avian influenza virus revealed substantial mammalian adaptation and pathogenicity, yet mechanisms remain unclear. To address this knowledge gap, we investigated ... Brigleb PH, Roubidoux EK, Lazure L, Livingston B,. Repeated oral exposure to H5N1 influenza virus in pasteurized milk does not cause adverse responses to subsequent influenza infection. Sci Adv. 2025 Sep 26;11(39):eaeb3906. Abstract
submitted by kickingbird at Sep, 27, 2025 from Sci Adv. 2025 Sep 26;11(39):eaeb3906 (via https://www.science.org/doi/10.1126/sciadv.aeb3906)
In March 2024, a highly pathogenic avian influenza H5N1 (HPAI) clade 2.3.4.4b virus was identified in US dairy cows, with spillover to cats, poultry, and humans. Up to 30% of commercial pasteurized milk ... Lee J, Lee CW, Lee S, Ibrahim S, Suarez DL, Spackm. The Efficacy of Inactivated Vaccine Against H5 Clade 2.3.4.4b Highly Pathogenic Avian Influenza Virus in Turkeys. Avian Dis. 2025 Sep;69(3):288-294. Abstract
submitted by kickingbird at Sep, 27, 2025 from Avian Dis. 2025 Sep;69(3):288-294 (via https://bioone.org/journals/avian-diseases/volume-69/issue-3)
The global outbreak of clade 2.3.4.4b H5 highly pathogenic avian influenza (HPAI) has caused tremendous losses in poultry worldwide. Although turkeys are a smaller sector in poultry production compared ... Verma AK, Kumar M, Murugkar HV, Nagarajan S, Tosh. Evaluation of In-Contact Transmission Potential of H5N1 Avian Influenza Virus in House Crows (Corvus splendens). Avian Dis . 2025 Sep;69(3):237-242.. Abstract
submitted by kickingbird at Sep, 27, 2025 from Avian Dis . 2025 Sep;69(3):237-242. (via https://bioone.org/journals/avian-diseases/volume-69/issue-3)
We evaluated the infection and transmission potential of the highly pathogenic avian influenza (HPAI) H5N1 virus from infected crows (Corvus splendens) to healthy in-contact crows. Six crows were inoculated ... Yixi Wu, Minke Li, Huanhuan Li, Tianli sun, Yifan. [preprint]Cryo-EM structure of influenza polymerase bound to the cRNA promoter provides insights into the mechanism of virus replication. https://doi.org/10.1101/2025.09.23.677976. Abstract
submitted by kickingbird at Sep, 27, 2025 from https://doi.org/10.1101/2025.09.23.677976 (via https://www.biorxiv.org/content/10.1101/2025.09.23.677976v1)
Influenza virus polymerase (FluPol) synthesizes the complementary RNA (cRNA) and the viral RNA (vRNA) using distinct de novo initiation strategies during genome replication, known as internal and terminal ... Alkie TN, Embury-Hyatt C, Signore AV, Ramos D, Mof. Dairy cow- and avian-origin clade 2.3.4.4b H5N1 induce severe mastitis in lactating goats and transmission to suckling goats. Cell Rep . 2025 Sep 24;44(10):116346.. Abstract
submitted by kickingbird at Sep, 26, 2025 from Cell Rep . 2025 Sep 24;44(10):116346. (via https://www.cell.com/cell-reports/fulltext/S2211-1247(25)011)
The emergence of highly pathogenic avian influenza (HPAI) H5N1 clade 2.3.4.4b has led to unprecedented spillover and spread among US dairy cows, raising concerns about transmission to other ruminants. ... Chavoix C, Massin P, Briand FX, Louboutin K, Busso. Identification of H1N2 influenza viruses in turkeys after spillover from swine and in vitro characterization. Virus Res. 2025 Sep 21:199634. Abstract
submitted by kickingbird at Sep, 25, 2025 from Virus Res. 2025 Sep 21:199634 (via https://www.sciencedirect.com/science/article/pii/S016817022)
Influenza A viruses (IAVs) circulate among animals and humans and can cross species barriers to adapt to new hosts. In France, since 2020, a new genotype named H1avN2#E has predominated in pig farms. In ... Wang Y, Gao YD, Jiang CH, Xi Y, Yang MX, Zhang W,. Characterisation of a novel chicken-derived H3N3 avian influenza virus detected in China in 2023: Pathogenicity and immunogenicity. PLoS One. 2025 Sep 23;20(9):e0332213. Abstract
submitted by kickingbird at Sep, 25, 2025 from PLoS One. 2025 Sep 23;20(9):e0332213 (via https://journals.plos.org/plosone/article?id=10.1371/journal)
The poultry industry faces a constant threat from the mutation and transmission of avian influenza viruses (AIVs). While waterfowl and wild birds are natural hosts of H3N3 AIV, reports of H3N3 infections ... Zhu B, Fung K, Feng HH, Beatty JA, Hill F, Tse ACN. The hemagglutinin proteins of clades 1 and 2.3.4.4b H5N1 highly pathogenic avian influenza viruses exhibit comparable attachment patterns to avian and mammalian tissues. J Virol. 2025 Sep 23:e0097625. Abstract
submitted by kickingbird at Sep, 25, 2025 from J Virol. 2025 Sep 23:e0097625 (via https://journals.asm.org/doi/10.1128/jvi.00976-25)
The global spread of the A/goose/Guangdong/1/96-lineage H5N1 highly pathogenic avian influenza (HPAI) viruses has been accompanied by an expanded host range and the establishment of sustained viral transmission ... Janzen GM, Inderski BT, Chang J, Arendsee ZW, Jana. Sources and sinks of influenza A virus genomic diversity in swine from 2009 to 2022 in the United States. J Virol. 2025 Sep 23;99(9):e0054125. Abstract
submitted by kickingbird at Sep, 25, 2025 from J Virol. 2025 Sep 23;99(9):e0054125 (via https://journals.asm.org/doi/10.1128/jvi.00541-25)
Influenza A virus (IAV) in swine in the U.S. is surveilled to monitor genetic evolution to inform intervention efforts and aid pandemic preparedness. We describe data from the U.S. Department of Agriculture ... Soliani L, Mescoli A, Zanni I, Baioni L, Alborali. Human-Derived H3N2 Influenza A Viruses Detected in Pigs in Northern Italy. Viruses. 2025; 17(9):1171. Abstract
submitted by kickingbird at Sep, 23, 2025 from Viruses. 2025; 17(9):1171 (via https://www.mdpi.com/1999-4915/17/9/1171)
In recent years, the four main swine influenza A virus (IAV-S) subtypes circulating in swine in the EU have been H1avN1, H1huN2, H1N1pdm09, and H3N2. The latter emerged in 1984 from a reassortment event ... Dua A, Trehan B, Bilasy SE, Yang C, ElShamy A. Gastrointestinal Infiltration in Influenza Virus Infection: Mechanisms and Clinical Insights. Viruses. 2025; 17(9):1187. Abstract
submitted by kickingbird at Sep, 22, 2025 from Viruses. 2025; 17(9):1187 (via https://www.mdpi.com/1999-4915/17/9/1187)
Background: Influenza, a primarily respiratory illness, frequently manifests with gastrointestinal (GI) symptoms including nausea, vomiting, diarrhea, and abdominal pain. In this review, we analyze mechanisms ... Joshua Wiggins, Adthakorn Madapong, Eric A Weaver. [preprint]Dual-Route H5N1 Vaccination Induces Systemic and Mucosal Immunity in Murine and Bovine Models. https://doi.org/10.1101/2025.09.21.677614. Abstract
submitted by kickingbird at Sep, 22, 2025 from https://doi.org/10.1101/2025.09.21.677614 (via https://www.biorxiv.org/content/10.1101/2025.09.21.677614v1)
Since its discovery in U.S. dairy cattle in early 2024, the highly pathogenic H5N1 avian influenza (clade 2.3.4.4b) has spread widely among herds, causing major economic losses. This zoonotic event emphasizes ... Minxi Jiang, etc.,al. [preprint]Developing and Benchmarking One Health Genomic Surveillance Tools for Influenza A Virus in Wastewater. https://doi.org/10.1101/2025.09.19.676942. Abstract
submitted by kickingbird at Sep, 22, 2025 from https://doi.org/10.1101/2025.09.19.676942 (via https://www.biorxiv.org/content/10.1101/2025.09.19.676942v1)
Influenza A viruses (IAV) remain a persistent One Health threat, and whole-genome sequencing from wastewater offers a promising surveillance tool. However, IAV is at low abundance in wastewater, making ... Indr? Blagnyt?, etc.,al. [preprint]Phylogeographic analysis of Influenza D virus evolution. https://doi.org/10.1101/2025.09.19.677308. Abstract
submitted by kickingbird at Sep, 22, 2025 from https://doi.org/10.1101/2025.09.19.677308 (via https://www.biorxiv.org/content/10.1101/2025.09.19.677308v1)
Influenza D virus (IDV), first identified in 2011 and primarily affecting cattle, has since been detected in a wide range of mammalian hosts and geographic regions. Despite widespread circulation in domestic ... Rebecca M. Schneider, etc.,al. [preprint]The structures of tetrameric Avian Immunoglobulin A are uniquely structured to support mucosal immunity. https://doi.org/10.1101/2025.09.19.677352. Abstract
submitted by kickingbird at Sep, 22, 2025 from https://doi.org/10.1101/2025.09.19.677352 (via https://www.biorxiv.org/content/10.1101/2025.09.19.677352v1)
Birds and mammals assemble polymeric (p) forms of immunoglobulin (Ig) A, which are transported to mucosal surfaces and released as secretory (S) IgA, the predominant mucosal antibody. Mammalian SIgA, which ... Harit D, Sawant S, Spreng RL, Gurley S, Schechter. Qualification of a reporter virus microneutralization assay for evaluation of influenza specific antibodies in human clinical trials. Vaccine. 2025 Sep 19;64:127699. Abstract
submitted by kickingbird at Sep, 22, 2025 from Vaccine. 2025 Sep 19;64:127699 (via https://www.sciencedirect.com/science/article/abs/pii/S02644)
Neutralizing antibodies can block the entry of viruses into host cells. Next-generation influenza vaccines should stimulate the production of high levels of neutralizing antibodies capable of preventing ... Danuta M Skowronski, etc.,al. [preprint]Cross-reactive neuraminidase inhibition antibodies against H5N1 by consecutive influenza A imprinting cohorts of the past century: population-based serosurvey, British Columbia, Canada. https://doi.org/10.1101/2025.09.19.25336209. Abstract
submitted by kickingbird at Sep, 22, 2025 from https://doi.org/10.1101/2025.09.19.25336209 (via https://www.medrxiv.org/content/10.1101/2025.09.19.25336209v)
Background: Avian influenza of the H5N1 subtype shares substantial relatedness in its neuraminidase (NA) surface protein with human influenza A H1N1 viruses of the past century. Understanding variation ... Jun-Qing Wei, Sen Zhang, Ya- Dan Li, Shu-Yang Jian. Deep learning predicts potential reassortments of avian H5N1 with human influenza viruses. National Science Review, 2025;, nwaf396. Abstract
submitted by kickingbird at Sep, 22, 2025 from National Science Review, 2025;, nwaf396 (via https://academic.oup.com/nsr/advance-article/doi/10.1093/nsr)
Frequent infection cases with avian H5N1 influenza A viruses (IAVs) are posing pandemic risks of human/avian-reassorted IAVs. We aimed to build an attentional deep learning model named HAIRANGE, for predicting ... 6499 items, 20/Page, Page[13/325][|<<] [|<] [11] [12] [13] [14] [15] [16] [17] [18] [19] [20] [>|] [>>|] |
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